LOCUS NC_001408 7286 bp ss-RNA linear VRL 13-AUG-2018
DEFINITION Avian leukosis virus - RSA, complete genome.
ACCESSION NC_001408
VERSION NC_001408.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Avian leukosis virus - RSA
ORGANISM Avian leukosis virus - RSA
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus;
Avian leukosis virus.
REFERENCE 1 (bases 1 to 7286)
AUTHORS Bieth,E. and Darlix,J.L.
TITLE Complete nucleotide sequence of a highly infectious avian leukosis
virus
JOURNAL Nucleic Acids Res. 20 (2), 367 (1992)
PUBMED 1311072
REFERENCE 2 (bases 1 to 7286)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2000) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 7286)
AUTHORS Bieth,E.
TITLE Direct Submission
JOURNAL Submitted (24-AUG-1990) CRBGC du CNRS, 118 route de Narbonne,
Toulouse 31062 Cedex, France
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to M37980.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..7286
/organism="Avian leukosis virus - RSA"
/mol_type="genomic RNA"
/db_xref="taxon:363745"
5'UTR 1..371
misc_feature 1..21
/note="5' terminal redundancy"
misc_feature 1
/note="CAP site"
regulatory 10..41
/regulatory_class="ribosome_binding_site"
misc_feature 22..101
/note="U5 region"
repeat_region 91..101
/note="5'imperfect repeat"
/rpt_type=terminal
misc_feature 102..371
/note="leader sequence"
protein_bind 102..120
/bound_moiety="primer"
misc_feature 210..270
/note="dimer promoting sequence"
misc_feature 218..248
/note="encapsidation element"
regulatory 331..371
/regulatory_class="ribosome_binding_site"
gene 372..6872
/gene="env"
/locus_tag="ALVgp01"
/db_xref="GeneID:1491907"
CDS join(372..388,5069..6872)
/gene="env"
/locus_tag="ALVgp01"
/codon_start=1
/product="envelope protein"
/protein_id="NP_040548.1"
/db_xref="GeneID:1491907"
/translation="MEAVIKAFLTGYPGKTSKKDSKEKPLATSKKDPEKTPLLPTRVN
YILIIGVLVLCEVTGVRADVHLLEQPGNLWITWANRTGQTDFCLSTQSATSPFQTCLI
GIPSPISEGDFKGYVSDNCTTLGTDRLVSSADFTGGPDNSTTLTYRKVSCLLLKLNVS
MWDEPHELQLLGSQSLPNITNIAQISGITGGCVGFRPQGVPWYLGWSRQEATRFLLRH
PSFSKSTEPFTVVTADRHNLFMGSEYCGAYGYRFWNMYNCSQVGRQYRCGNARSPRPG
LPEIQCTRRGGKWVNQSQEINESEPFSFTVNCTASSLGNASGCCGKAGTILPGKWVDS
TQGSFTKPKALPPAIFLICGDRAWQGIPSRPVGGPCYLGKLTMLAPKHTDILKVLVNS
SRTGIRRKRSTSHLDDTCSDEVQLWGPTARIFASILAPGVARAQALREIERLACWSVK
QANLTTSFLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDVAGMCCFNLSDHSES
IQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCL
PCLLQIVCGNIRKMINNSISYHTEYKKLQKACGQPESRIV"
misc_feature 5520..6257
/gene="env"
/locus_tag="ALVgp01"
/note="Avian retrovirus envelope protein, gp85; Region:
Avian_gp85; pfam03708"
/db_xref="CDD:281671"
misc_feature 6390..6605
/gene="env"
/locus_tag="ALVgp01"
/note="heptad repeat 1-heptad repeat 2 region (ectodomain)
of the transmembrane subunit of Rous sarcoma virus (RSV),
and related domains; Region: RSV-like_HR1-HR2; cd09949"
/db_xref="CDD:197372"
misc_feature order(6390..6398,6402..6407,6411..6416,6420..6428,
6432..6440,6444..6449,6453..6461,6465..6491,6495..6503,
6528..6533,6540..6542,6549..6560,6564..6566,6582..6584,
6591..6596,6603..6605)
/gene="env"
/locus_tag="ALVgp01"
/note="homotrimer interface [polypeptide binding]; other
site"
/db_xref="CDD:197372"
misc_feature 6390..6503
/gene="env"
/locus_tag="ALVgp01"
/note="HR1; other site"
/db_xref="CDD:197372"
misc_feature 6471..6521
/gene="env"
/locus_tag="ALVgp01"
/note="immunosuppressive region; other site"
/db_xref="CDD:197372"
misc_feature 6477..6479
/gene="env"
/locus_tag="ALVgp01"
/note="Cl binding site [ion binding]; other site"
/db_xref="CDD:197372"
misc_feature 6522..6545
/gene="env"
/locus_tag="ALVgp01"
/note="CX(6)C motif; other site"
/db_xref="CDD:197372"
misc_feature 6579..6605
/gene="env"
/locus_tag="ALVgp01"
/note="HR2; other site"
/db_xref="CDD:197372"
gene 372..2474
/gene="MAp19"
/locus_tag="ALVgp02"
/db_xref="GeneID:1491902"
misc_feature 372..2474
/gene="MAp19"
/locus_tag="ALVgp02"
/note="3' imperfect repeat; matrix protein"
gene 372..1029
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/db_xref="GeneID:1491911"
CDS join(372..387,674..1029)
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/codon_start=1
/product="trans-acting factor"
/protein_id="NP_040549.1"
/db_xref="GeneID:1491911"
/translation="MEAVIREGGSLPQVRSASRNQQRSGESTKGRKWEKQLRSEMRRW
RRRKWPHLKPLAHPAISAEQLLAVIAPQPRPLLLLMWGVVCILPWRGWESSRARGVTH
LGGRNSQGRSQGTRVWPLGRP"
protein_bind 423..440
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/bound_moiety="nucleocapsid"
protein_bind 502..511
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/bound_moiety="nucleocapsid"
misc_feature 512..540
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/note="dimer linkage structure"
misc_feature 536..556
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/note="dimer linkage structure"
misc_feature 701..792
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/note="negative splicing regulator"
protein_bind 805..818
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/bound_moiety="nucleocapsid"
misc_feature 817..876
/gene="trans-acting factor"
/locus_tag="ALVgp03"
/note="enhancer domain"
gene 837..902
/gene="p2"
/locus_tag="ALVgp04"
/db_xref="GeneID:1491909"
protein_bind 880..897
/gene="p2"
/locus_tag="ALVgp04"
/bound_moiety="nucleocapsid"
gene 903..1088
/gene="p10"
/locus_tag="ALVgp05"
/db_xref="GeneID:1491908"
gene 1836..2102
/gene="NCp12"
/locus_tag="ALVgp06"
/db_xref="GeneID:1491903"
misc_feature 1836..2102
/gene="NCp12"
/locus_tag="ALVgp06"
/note="nucleocapsid protein"
protein_bind 1941..1948
/gene="NCp12"
/locus_tag="ALVgp06"
/bound_moiety="nucleocapsid"
gene 2103..2474
/gene="PRp15"
/locus_tag="ALVgp07"
/db_xref="GeneID:1491904"
misc_feature 2103..2474
/gene="PRp15"
/locus_tag="ALVgp07"
/note="neutral protease large subunit"
protein_bind 2388..2400
/gene="PRp15"
/locus_tag="ALVgp07"
/bound_moiety="nucleocapsid"
gene <2495..5182
/gene="pol"
/locus_tag="ALVgp08"
/db_xref="GeneID:1491910"
CDS <2495..5182
/gene="pol"
/locus_tag="ALVgp08"
/codon_start=1
/product="polymerase"
/protein_id="NP_040550.1"
/db_xref="GeneID:1491910"
/translation="TVALHLAIPLKWKPDHTPVWIDQWPLPEGKLVALTQLVEKELQL
GHIEPSLSCWNTPVFVIRKASGSYRLLHDLRAVNAKLVPFGAVQQGAPVLSALPRGWP
LMVLDLKDCFFSIPLAEQDREAFAFTLPSVNNQAPARRFQWKVLPQGMTCSPTICQLV
VGQVLEPLRLKHPSLRMLHYMDDLLLAASSHDGLEAAGEEVISTLERAGFTISPDKIQ
REPGVQYLGYKLGSTYVAPVGLVAEPRIATLWDVQKLVGSLQWLRPALGIPPRLMGPF
YEQLRGSDPNEAREWNLDMKMAWREIVQLSTTAALERWDPALPLEGAVARCEQGAIGV
LGQGLSTHPRPCLWLFSTQPTKAFTAWLEVLTLLITKLRASAVRTFGKEVDILLLPAC
FREDLPLPEGILLALRGFAGKIRSSDTPSIFDIARPLHVSLKVRVTDHPVPGPTAFTD
ASSSTHKGVVVWREGPRWEIKEIADLGASVQQLEARAVAMALLLWPTTPTNVVTDSAF
VAKMLLKMGQEGVPSTAAAFILEDALSQRSAMAAVLHVRSHSEVPGFFTEGNDVADSQ
ATFQAYPLREAKDLHTALHIGPRALSKACNISMQQAREVVQTCPHCNSAPALEAGVNP
RGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAAQHHWATAIA
VLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNSQGQAMVERANRLLKDKIR
VLAEGDGFMKRIPTSKQGELLAKAMYALNHFERGENTKTPIQKHWRPTVLTEGPPVKI
RIETGEWEKGWNVLVWGRGYAAVKNRDTDKVIWVPSRKVKPDVTQKDEVTKKDEASPL
FAGISDWIPWEDEQEGLQGETASNKQERPGEDTLAANES"
misc_feature 2546..3184
/gene="pol"
/locus_tag="ALVgp08"
/note="Reverse transcriptases (RTs) from retroviruses
(Rtvs). RTs catalyze the conversion of single-stranded RNA
into double-stranded viral DNA for integration into host
chromosomes. Proteins in this subfamily contain long
terminal repeats (LTRs) and are...; Region: RT_Rtv;
cd01645"
/db_xref="CDD:238823"
misc_feature order(2564..2569,2669..2671,2681..2683,2699..2701,
2705..2713,2717..2719,2726..2728,2750..2752,2756..2761,
2765..2767,2813..2830,2936..2941,2945..2947,2954..2956,
3032..3034,3038..3043,3170..3175)
/gene="pol"
/locus_tag="ALVgp08"
/note="active site"
/db_xref="CDD:238823"
misc_feature order(2564..2569,2705..2713,2717..2719,2726..2728,
2750..2752,2756..2761,2765..2767,2939..2941,2945..2947,
2954..2956,3032..3034,3170..3175)
/gene="pol"
/locus_tag="ALVgp08"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:238823"
misc_feature order(2681..2683,2699..2701,2813..2830,2936..2938,
3038..3040)
/gene="pol"
/locus_tag="ALVgp08"
/note="dNTP binding site [chemical binding]; other site"
/db_xref="CDD:238823"
misc_feature order(2783..2794,3020..3022,3026..3028,3047..3049,
3053..3055,3161..3163)
/gene="pol"
/locus_tag="ALVgp08"
/note="NNRTI binding site [active]"
/db_xref="CDD:238823"
misc_feature 3227..3367
/gene="pol"
/locus_tag="ALVgp08"
/note="Reverse transcriptase thumb domain; Region:
RVT_thumb; pfam06817"
/db_xref="CDD:429135"
misc_feature 3830..4207
/gene="pol"
/locus_tag="ALVgp08"
/note="Ribonuclease H-like superfamily, including RNase H,
HI, HII, HIII, and RNase-like domain IV of spliceosomal
protein Prp8; Region: RNase_H_like; cl14782"
/db_xref="CDD:449355"
misc_feature order(3842..3853,3932..3937,3944..3946,4007..4009,
4127..4129,4196..4198)
/gene="pol"
/locus_tag="ALVgp08"
/note="RNA/DNA hybrid binding site [nucleotide binding];
other site"
/db_xref="CDD:259998"
misc_feature 4229..4336
/gene="pol"
/locus_tag="ALVgp08"
/note="Integrase Zinc binding domain; Region:
Integrase_Zn; pfam02022"
/db_xref="CDD:426567"
misc_feature 4379..4660
/gene="pol"
/locus_tag="ALVgp08"
/note="Integrase core domain; Region: rve; pfam00665"
/db_xref="CDD:425808"
misc_feature 2495..5179
/gene="pol"
/locus_tag="ALVgp08"
/note="reverse transcriptase beta-subunit"
misc_feature 2495..4210
/gene="pol"
/locus_tag="ALVgp08"
/note="reverse transcriptase alpha-subunit"
protein_bind 2950..2964
/gene="pol"
/locus_tag="ALVgp08"
/bound_moiety="nucleocapsid"
gene 4211..5179
/gene="INp32"
/locus_tag="ALVgp09"
/db_xref="GeneID:1491901"
misc_feature 4211..5179
/gene="INp32"
/locus_tag="ALVgp09"
/note="integrase"
protein_bind 4747..4758
/gene="INp32"
/locus_tag="ALVgp09"
/bound_moiety="nucleocapsid"
gene 5244..6260
/gene="SU"
/locus_tag="ALVgp10"
/db_xref="GeneID:1491905"
misc_feature 5244..6260
/gene="SU"
/locus_tag="ALVgp10"
/note="surface protein"
protein_bind 5712..5727
/gene="SU"
/locus_tag="ALVgp10"
/bound_moiety="nucleocapsid"
protein_bind 6187..6201
/gene="SU"
/locus_tag="ALVgp10"
/bound_moiety="nucleocapsid"
gene 6261..6869
/gene="TM"
/locus_tag="ALVgp11"
/db_xref="GeneID:1491906"
misc_feature 6261..6869
/gene="TM"
/locus_tag="ALVgp11"
/note="transmembrane protein"
protein_bind 6414..6425
/gene="TM"
/locus_tag="ALVgp11"
/bound_moiety="nucleocapsid"
repeat_region 7037..7047
/note="3'imperfect repeat"
/rpt_type=terminal
ORIGIN
1 gccatttgac cattcaccac attggtgtgc acctgggttg atggccggac cgttgattcc
61 ctgacgacta cgagcacctg catgaagcag aaggcttcat ttggtgaccc cgacgtgata
121 gttagggaat agtggtcggc cacagacggc gtggcgatcc tgtctccatc cgtctcgtct
181 atcgggaggc gagttcgatg accctggtgg agggggctgc ggcttaggga ggcagaagct
241 gagtaccgtc ggagggagct ccagggcccg gagcgactga cccctgccga gaactcagag
301 ggtcgtcgga agacggagag tgagcccgac gaccacccca ggcacgtctt tggtcggcct
361 gcggatcaag catggaagcc gtcattaagg tgatttcgtc cgcgtgtaaa acctattgcg
421 ggaaaatctc tccttctaag aaggaaatag gggccatgtt gtccctgtta caaaaggaag
481 ggttgcttat gtctccctca gatttatatt ccccggggtc ctgggatccc atcactgcgg
541 cgctctccca gcgggcaatg gtacttggga aatcgggaga gttaaaaacc tggggattgg
601 ttttgggggc attgaaggcg gctcgagagg aacaggttac atctgagcaa gcaaagtttt
661 ggttgggatt agggggaggg agggtctctc ccccaggtcc ggagtgcatc gagaaaccag
721 caacggagcg gcgaatcgac aaaggggagg aagtgggaga aacaactgcg cagcgagatg
781 cgaagatggc gccggagaaa atggccacac ctaaaaccgt tggcacatcc tgctatcagt
841 gcggaacagc tactggctgt aattgcgcca cagcctcggc ccctcctcct ccttatgtgg
901 ggagtggttt gtatccttcc ctggcggggg tgggagagca gcagggccag gggggtgaca
961 caccttgggg ggcggaacag ccaagggcgg agccagggca cgcgggtctg gcccctgggc
1021 cggccctgac tgactgggca aggatcaggg aggagcttgc gagtacaggt ccgcccgtgg
1081 tggccatgcc tgtagtgatt aagacagagg gacccgcctg gacccctctg gagccaaaat
1141 tgatcacaag actggctgat acggtcagga ccaagggctt acgatccccg atcactatgg
1201 cagaagtgga agcgctcatg tcctccccgt tgctgccgca tgacgtcacg aatctaatga
1261 gagtgatttt aggacctgcc ccatatgcct tatggatgga cgcttgggga gtccaactcc
1321 agacggttat agcggcagcc actcgcgacc cccgacaccc agcgaacggt caagggcggg
1381 gggaacggac taacttggat cgattaaagg gcttagctga tgggatggtg ggcaacccac
1441 agggtcaggc cgcattatta agaccggggg aattggttgc tattacggcg tcggctctcc
1501 aggcgtttag agaagttgcc cggctggcgg aacctgcagg tccatgggcg gacatcacgc
1561 agggaccatc tgagtccttt gttgattttg ccaatcggct tataaaggcg gttgaggggt
1621 cagatctccc gccttccgcg cgggctccgg tgatcattga ctgctttagg cagaagtcac
1681 agccagatat tcagcagctt atacgggcag caccctccac gctgaccacc ccaggagaga
1741 taatcaaata tgtgctagac aggcagaaga ttgcccctct tacggatcaa ggcatagccg
1801 cggccatgtc gtctgctatc cagcccttag ttatggcagt agtcaataga gagagggatg
1861 gacaaactgg gtcgggtggt cgtgcccgag ggctctgcta cacttgtgga tccccgggac
1921 attatcaggc gcagtgcccg aaaaaacgaa agtcaggaaa cagccgtgag cgatgtcagc
1981 tgtgtgacgg gatgggacac aacgctaaac agtgcagaag gcgggatggc aaccagggcc
2041 aacgcccagg aaaaggcctc tcttcggggt cgtggcccgt ctctgagcag cctgccgtct
2101 cgttagcgat gacaatggaa cataaagatc gccccttggt tagggtcatt ctgactaaca
2161 ctgggagtca tccggtcaaa cagcgttcgg tgtatatcac cgcgctgttg gactctggag
2221 cggacatcac tattatttca gaggaggact ggcccaccga ttggccagtg atggaggccg
2281 cgaacccgca gatccatggg ataggagggg gaattcccat gcgaaaatcc cgggatatga
2341 tagaggtggg ggttattaac cgagacgggt ctttggagcg acccctgctc ctcttccccg
2401 cagtagctat ggttagaggg agtatcctag gaagagattg tctgcagggc ctagggctcc
2461 gcttgacaaa tttataggga gggccactgt tcttactgtt gcgctacatc tggctattcc
2521 gctcaaatgg aagccagacc acacgcctgt gtggattgac cagtggcccc ttcctgaagg
2581 taaacttgta gcgctaacgc aattagtgga aaaagaatta cagttaggac atatagaacc
2641 ttcacttagt tgttggaaca cacctgtctt tgtgatccgg aaggcttccg ggtcttatcg
2701 cttattgcat gacttgcgcg ctgttaacgc caagcttgtt ccttttgggg ccgtccaaca
2761 gggggcgcca gttctctccg cgctcccgcg tggctggccc ctgatggtcc tagacctcaa
2821 ggattgcttc ttttctattc ctcttgcgga acaagatcgc gaagcttttg catttacgct
2881 cccctctgtg aataaccagg cccccgctcg aagattccaa tggaaggtct tgccccaagg
2941 gatgacctgt tctcccacta tctgtcagtt ggtggtgggt caggtacttg agcccttgcg
3001 actcaagcac ccatctctgc gcatgttgca ttatatggat gatcttttgc tagccgcctc
3061 aagtcatgat gggttggaag cggcagggga ggaggttatc agtacattgg aaagagccgg
3121 gttcaccatt tcgcctgata agatccagag ggaacccgga gtacaatatc ttgggtacaa
3181 gttaggcagt acgtatgtag cacccgtagg cctggtagca gaacccagga tagccacctt
3241 gtgggatgtt caaaagctgg tggggtcact tcagtggctt cgcccagcgt taggaatccc
3301 gccacgactg atgggcccct tctatgagca gttacgaggg tcagatccta acgaggcgag
3361 ggaatggaat ctagacatga aaatggcctg gagagagatc gtacagctta gcaccactgc
3421 tgccttggaa cgatgggacc ctgccctgcc tttggaggga gcggtcgcta ggtgtgaaca
3481 gggggcaata ggggtcctgg gacagggact gtccacacac ccaaggccat gtttgtggtt
3541 attctccacc caacccacca aggcgtttac tgcttggtta gaagtgctca cccttttgat
3601 tactaagcta cgcgcttcgg cagtgcgaac ctttggcaag gaggttgata tcctcctgtt
3661 gcctgcatgc tttcgggagg accttccgct cccggagggg atcctgttag cccttagggg
3721 gtttgcagga aaaatcagga gtagtgacac gccatctatt tttgacattg cgcgtccact
3781 gcatgtttct ctgaaagtga gggtcaccga ccaccctgta ccgggaccca ctgcctttac
3841 cgacgcctcc tcaagcaccc ataaaggggt ggtagtctgg agggagggcc caaggtggga
3901 gataaaagaa atagctgatt tgggggcaag tgtacaacaa ctggaagcac gcgctgtggc
3961 catggcactt ctgctgtggc cgacaacgcc cactaatgta gtgactgact ccgcgtttgt
4021 cgcgaaaatg ttactcaaga tgggacagga gggagtcccg tctacagcgg cggcttttat
4081 tttagaggat gcgttaagcc aaaggtcagc catggccgcc gttctccacg tgcggagtca
4141 ttctgaagtg ccagggtttt tcacagaagg aaatgacgtg gcagatagcc aagccacctt
4201 tcaagcgtat cccttgagag aggctaaaga tcttcatact gctctccata ttggaccccg
4261 cgcgctatcc aaagcgtgta atatatctat gcagcaggct agggaggttg ttcagacctg
4321 cccgcattgt aattcagccc ctgcgttgga ggccggggta aaccctaggg gtttgggacc
4381 cctacagata tggcagacag actttacgct tgagcctaga atggcccccc gttcctggct
4441 cgctgttact gtggataccg cctcatcggc gatagtcgta actcagcatg gccgtgtcac
4501 atcggttgct gcacaacatc attgggccac ggctatcgcc gttttgggaa gaccaaaggc
4561 cataaaaaca gataatgggt cctgtttcac gtctaaatcc acgcgagagt ggctcgcgag
4621 atgggggata gcacacacca ccgggattcc gggtaattcc cagggtcaag ctatggtaga
4681 gcgggccaac cggctcctga aagataagat ccgtgtgctt gcggaggggg acggctttat
4741 gaaaagaatc cccaccagca aacaggggga actactagcc aaggcaatgt atgccctcaa
4801 tcactttgag cgcggtgaaa acacaaaaac accgattcaa aaacactgga gacctaccgt
4861 tcttacagaa ggacccccgg ttaaaatacg aatagagaca ggggagtggg aaaaaggatg
4921 gaatgtgctg gtctggggac gaggttatgc agctgtgaaa aacagggaca ctgataaggt
4981 tatttgggta ccctctcgga aagttaaacc ggatgtcacc caaaaggatg aggtgactaa
5041 gaaagatgag gcgagccctc tttttgcagg catttctgac tggataccct gggaagacga
5101 gcaagaagga ctccaaggag aaaccgctag caacaagcaa gaaagacccg gagaagacac
5161 ccttgctgcc aacgagagtt aattatattc tcattattgg tgtcctggtc ttgtgtgagg
5221 ttacgggggt aagagctgat gtccacttac tcgagcagcc agggaacctt tggattacat
5281 gggccaaccg tacaggccaa acggattttt gcctctctac acagtcagcc acctcccctt
5341 ttcaaacatg tttgataggt atcccgtccc ctatttccga aggtgatttt aagggatacg
5401 tctctgataa ttgcaccacc ttgggaactg atcggttagt ctcgtcagcc gactttactg
5461 gcggacctga caacagtacc accctcactt atcggaaggt ctcatgcttg ttgttaaagc
5521 tgaatgtctc tatgtgggat gagccacatg aactacagct gttaggttcc cagtctctcc
5581 ctaacattac taatattgct cagatttccg gtataaccgg gggatgcgta ggtttcagac
5641 cacaaggggt tccttggtat ctaggttggt ctagacagga ggccacgcgg tttctcctta
5701 gacacccctc tttctctaaa tccacggaac cgtttacggt ggtgacagcg gataggcaca
5761 atctttttat ggggagtgag tactgcggtg catatggcta cagattttgg aacatgtata
5821 actgctcaca ggtggggcgg cagtaccgct gtggtaatgc gcgcagcccc cgcccgggtc
5881 ttcctgaaat ccagtgtaca aggagaggag gcaaatgggt taatcaatca caggaaatta
5941 atgagtcgga gccgttcagc tttacggtga actgtacagc tagtagtttg ggtaatgcca
6001 gtgggtgttg cggaaaagca ggcacgattc tcccgggaaa gtgggtcgac agcacacaag
6061 gtagtttcac caaaccaaaa gcgctaccac ccgcaatttt cctcatttgt ggggatcgcg
6121 catggcaagg aattcccagt cgtccggtag ggggcccctg ctatttaggc aagcttacca
6181 tgttagcacc taagcataca gatattctca aggtgcttgt caattcatcg cggacaggta
6241 taagacgtaa acgaagcacc tcacacctgg atgatacatg ctcagatgaa gtgcagcttt
6301 ggggtcctac agcaagaatc tttgcatcta tcttagcccc gggggtagca cgtgcgcaag
6361 ccttaagaga aattgagaga ctagcctgtt ggtccgttaa acaggctaac ttgacaacat
6421 cattcctcgg ggacttattg gatgatgtca cgagtattcg acacgcggtc ctgcagaacc
6481 gagcggctat tgacttcttg cttctggctc acggccatgg ctgtgaggac gttgccggaa
6541 tgtgttgttt caatctgagt gatcacagtg agtctataca gaagaagttc cagctaatga
6601 aggaacatgt caataagatc ggcgtggaca gcgacccaat cggaagttgg ctgcgaggat
6661 tattcggggg aataggggaa tgggccgttc atttgctgaa aggactgctt ttggggcttg
6721 tagttatttt gttgctagta gtgtgcctgc cttgcctttt gcaaatcgta tgcggtaaca
6781 tcagaaagat gattaataac tccatcagct accacacgga atataagaag ctgcaaaagg
6841 cctgtgggca gcctgaaagc agaatagtat aaggcagtac atgggtggtg gtatagcgct
6901 tgcgagtcgg gttgtaacgg ggcatggctt aactaagggg actatggcat gtataggcgc
6961 aaagcggggc ttcggttgta cgcggttagg agtcccctca ggatatagta gtttcgcttt
7021 tgcataggga gggggaaatg tagtcttatg caatactctt gtagtcttgc aacatggtaa
7081 cgatgagtta gcaacatgcc ttacaaggag agaaaaagca ccgtgcatgc cgattggtgg
7141 aagtaaggtg gtacgatcgt gccttattag gaaggcaaca gacgggtctg acatggattg
7201 gacgaaccac tgaattccgc attgcagaga tattgtattt aagtgcctag ctcgatacaa
7261 taaacgccat ttgaccattc accaca
//
