LOCUS NC_001445 9741 bp ss-RNA linear VRL 13-AUG-2018
DEFINITION Plum pox virus, complete genome.
ACCESSION NC_001445
VERSION NC_001445.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Plum pox virus
ORGANISM Plum pox virus
Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
Patatavirales; Potyviridae; Potyvirus.
REFERENCE 1 (bases 1 to 9741)
AUTHORS Maiss,E., Timpe,U., Brisske,A., Jelkmann,W., Casper,R., Himmler,G.,
Mattanovich,D. and Katinger,H.W.
TITLE The complete nucleotide sequence of plum pox virus RNA
JOURNAL J. Gen. Virol. 70 (PT 3), 513-524 (1989)
PUBMED 2732699
REFERENCE 2 (bases 1 to 9741)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2000) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from D13751.
cDNA prepared by primer extension was used to determine the 5'
terminus.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..9741
/organism="Plum pox virus"
/mol_type="genomic RNA"
/isolate="PPV-NAT"
/db_xref="taxon:12211"
/clone="pPPV-NAT[274, 31, 47, 232, 65]"
/note="PPV-NAT genome excluding the 3' poly-A tail;
propagated in Nicotiana clevelandii"
misc_feature 14..25
/note="conserved sequence for potyvirus"
gene 147..9524
/locus_tag="PlPVgp1"
/db_xref="GeneID:1494049"
CDS 147..9524
/locus_tag="PlPVgp1"
/codon_start=1
/product="polyprotein"
/protein_id="NP_040807.1"
/db_xref="GeneID:1494049"
/translation="MSTIVFGSFTCHLDAAIHQDNADRLAKAWTRPENRQVSNAHLLC
RRAAESLINTYESATASAWKGLEEKLQPMFAKREFSKTVTKRKGLRCFKESSEKFIEK
KLRKQYQEERERLQFLNGPDAIVNQISVDKCEASVRVPSPHIIEKPSFVTPSMKKKVV
FKKVRMSEASLQLFMRRVAANAKANGQKVEIIGRKRVVGNYTTKSRLTYFRTHVRHLD
GSKPRYDLVLDEATKKILQLFANTSGFHHVHKKGEVTPGMSGFVVNPMNLSDPMQVYD
TDLFIVRGKHNSILVDSRCKVSKKQSNEIIHYSDPGKQFSDGFTNSFMQCKLRETDHQ
CTSDLDVKECGYVAALVCQAIIPCGKITCLQCAQKYSYMSQQEIRDRFSTVIEQHEKT
VMDNYPQFSHVLAFLKRYRELMRVENQNYEAFKDITHMIGERKEAPFSHLNKINELII
KGGMMSAQDYIEASDHLRELARYQKNRTENIRSGSIKAFRNKISSKAHVNMQLMCDNQ
LDTNGNFVWGQREYHAKRFFRNYFDVIDVSEGYRRHIVRENPRGIRKLAIGNLVMSTN
LAALRKQLLGEECIHFEVSKECTSKRGENFVYQCCCVTHEDGTPLESEIISPTKNHLV
VGNSGDSKYVDLPTAKGGAMFIAKAGYCYINIFLAMLININEDEAKSFTKTVRDTLVP
KLGTWPSMMDLATACHFLAVLYPETRNAELPRILVDHEAKIFHVVDSFGSLSTGMHVL
KANTINQLISFASDTLDSNMKTYLVGGLEVDKCDEFKNVKLLIRSIYKPQIMEQVLKE
EPYLLLMSVLSPGVLMALFNSGSLEKATQYWITRSHSLAAITSMLSALAAKVSLASTL
NAQMSVIDEHAAVLYDSVFVGTQPYASYMMAVKTLERMKARTESDHTLNDLGFSVLRQ
ATPHLVEKSYLQELEQAWKELSWSEKFSAILESQRWRKHIPKPFIPKDGADLGGRYDI
SVRSLLGNQYKRLRDVVRWKRDDVVCYTYQSMGKLFCKAIGISPSFLPSTLKMLDMLI
VFSLLLSIGATCNSMVNEHKHLKQLAADREDKKRFKRLQVLYTRLSEKVGCTPTADEF
LEYVGDENPDLLKHAEDLIGDGQVVVHQSKRDSQANLERVVAFVALVMMLFDSERSDG
VYKILNKLKGIMGSVDRAVHHQSLDDIEDILDEKKLTVDFVLQSNEVAPTVPFDSTFE
KWWMNQLETGNVIPHYRTEGHFLEFTRENAAHIANEVMHGSHQDILIRGAVGSGKSTG
LPFHLSKKGHVLLIEPTRPLAENVCKQLRGQPFNVNPTLRMRGMSTFGSTPITVMTSG
YALHFLANNPTYLDNYKCIIFDECHVHDASAMAFRCLLSEYSYPGKILKVSATPPGHE
VEFKTQKEVKVIVEESLSFQQFVSNLGTGCNSDILKHGVNVLVYVASYNEVDTLSKLL
TDRSFKVSKVDGRTMKVGNVEIPTSGTQAKPHFVVATNIIENGVTLDIDVVVDFGLKV
VPVLDIDNRLVRYTKKSISYGERIQRLGRVGRNKPGAALRIGFTEKGLTQIPPIIATE
AAFLCFTYGLPVMTNGVSTSLLAMCTVKQARTMQQFELSPFYTVALVRFDGTMHQEIF
RLLKSYRLRDSEVILNKLAIPNSNVCGWMSVRDYKRQGCNLDLDENIRVPFYVKDIPE
TLHERIWQAVETHKSDAGFGRICSSSACKIAYTLQTDIHSIPRTIKIIDALLEQERTK
QAHFRAMTSQSCSSSNFSLSSITSAIRSKYAKDHTEENIGVLQMAKSQLLEFKNLNID
PSYPELIRNFGALECVHHQTKEGVSKALQLKGHWNKRLITRDATLMLGVLGGGAWMIF
SYLRDSFKEEVIHQGFNRRQRQKLKFRQARDNRMAREVYGDDSTMEAYFGSAYSKKGK
SKGKTRGMGTKTRKFVNMYGYDPTDYNFVRFVDPLTGHTLDESPLMDINLVQEHFSQI
RNDYIGDDKITMQHIMSNPGIVAYYIKDATQKALKVDLTPHNPLRVCDKTATIAGFPE
REFELRQTGHPVFVEPNAIPKINEEGDEEVDHESKSLFRGLRDYNPIASSICQLNNSS
GARQSEMFGLGFGGLIVTNQHLFKRNDGELTIRSHHGEFVVKDTKTLKLLPCKGRDIV
IIRLPKDFPPFPRRLQFRTPTTEDRVCLIGSNFQTKSISSTMSETSATYPVDNSHFWK
HWISTKDGHCGLPIVSTRDGSILGLHSLANSTNTQNFYAAFPDNFETTYLSNQDNDNW
IKQWRYNPDEVCWGSLQLKRDIPQSPFTICKLLTDLDGEFVYTQSKTTHWLRDRLEGN
LKAVGACPGQLVTKHVVKGKCTLFETYLLTHPEEHEFFRPLMGAYQKSALNKDAYVKD
LMKYSKPIVVGAVDCDQFERAVDVVISMLISKGFEECNYVTDPDDIFSALNMKAAVGA
LYSGKKRDYFENVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEKVEANKTRS
FTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLKALPEGWIYCD
ADGSQFDSSLSPYLINAVLNIRLAFMEEWDIGEQMLSNLYTEIVYTPIATPDGTIVKK
FKGNNSGQPSTVVDNTLMVILAMTYSLLKLGHHPDTHDCICRYFVNGDDLVLAVHPAY
ESIYDELQEHFSQLGLNYTFTTKTENKEELWFMSHKGVLYDDMYIPKLEPERIVSILE
WDRSNEPIHRLEAICASMVEAWGYKELLREIRKFYSWVLEQAPYNALSKDGKAPYIAE
TALKKLYTDTEASETEIERYLEAFYDNINDDGESNVVVHQADEREDEEEVDALQPPPV
IQPAPRTTAPMLNPIFTPATTQPATKPVSQVSGPQLQTFGTYSHEDASPSNSNALVNT
NRDRDVDAGSTGTFTVPRLKAMTSKLSLPKVKGKAIMNLNHLAHYSPAQVDLSNTRAP
QSCFQTWYEGVKRDYDVTDDEMSIILNGLMVWCIENGTSPNINGMWVMMDGETQVEYP
IKPLLDHAKPTFRQIMAHFSNVAEAYIEKRNYEKAYMPRYGIQRNLTDYSLARYAFDF
YEMTSTTPVRAREAHIQMKAAALRNVQNRLFGLDGNVGTQEEDTERHTAGDVNRNMHN
LLGMRGV"
mat_peptide 147..1070
/locus_tag="PlPVgp1"
/product="P1 protein"
/note="protease"
/protein_id="NP_734339.1"
mat_peptide 1071..2444
/locus_tag="PlPVgp1"
/product="HC-Pro protein"
/protein_id="NP_734340.1"
misc_feature 1137..2444
/locus_tag="PlPVgp1"
/note="Helper component proteinase; Region: Peptidase_C6;
pfam00851"
/db_xref="CDD:279223"
mat_peptide 2445..3494
/locus_tag="PlPVgp1"
/product="P3 protein"
/protein_id="NP_734341.1"
misc_feature 2487..3803
/locus_tag="PlPVgp1"
/note="Protein P3 of Potyviral polyprotein; Region:
Potyvirid-P3; pfam13608"
/db_xref="CDD:290339"
mat_peptide 3495..3650
/locus_tag="PlPVgp1"
/product="6K1 protein"
/protein_id="NP_734342.1"
mat_peptide 3651..5555
/locus_tag="PlPVgp1"
/product="CI protein"
/protein_id="NP_734343.1"
misc_feature 3810..4346
/locus_tag="PlPVgp1"
/note="DEAD-like helicases superfamily; Region: DEXDc;
smart00487"
/db_xref="CDD:214692"
misc_feature order(3912..3929,4170..4172)
/locus_tag="PlPVgp1"
/note="putative ATP binding site [chemical binding]; other
site"
/db_xref="CDD:350670"
misc_feature 4383..4730
/locus_tag="PlPVgp1"
/note="Helicase conserved C-terminal domain; Region:
Helicase_C; pfam00271"
/db_xref="CDD:425571"
misc_feature 4803..5624
/locus_tag="PlPVgp1"
/note="Potyviridae polyprotein; Region: Poty_PP;
pfam08440"
/db_xref="CDD:285618"
mat_peptide 5556..5714
/locus_tag="PlPVgp1"
/product="6K2 protein"
/protein_id="NP_734344.1"
mat_peptide 5715..6293
/locus_tag="PlPVgp1"
/product="NIa-VPg protein"
/protein_id="NP_734345.1"
misc_feature 6288..6989
/locus_tag="PlPVgp1"
/note="Peptidase family C4; Region: Peptidase_C4;
pfam00863"
/db_xref="CDD:279235"
mat_peptide 6294..7022
/locus_tag="PlPVgp1"
/product="NIa-Pro protein"
/protein_id="NP_734346.1"
mat_peptide 7023..8576
/locus_tag="PlPVgp1"
/product="NIb protein"
/protein_id="NP_734347.1"
misc_feature 7506..8213
/locus_tag="PlPVgp1"
/note="catalytic core domain of RNA-dependent RNA
polymerase (RdRp) in the family Potyviridae of
positive-sense single-stranded RNA [(+)ssRNA] viruses;
Region: ps-ssRNAv_Potyviridae_RdRp; cd23175"
/db_xref="CDD:438025"
misc_feature 7749..7793
/locus_tag="PlPVgp1"
/note="conserved polymerase motif A; other site"
/db_xref="CDD:438025"
misc_feature 7944..8015
/locus_tag="PlPVgp1"
/note="conserved polymerase motif B; other site"
/db_xref="CDD:438025"
misc_feature 8055..8099
/locus_tag="PlPVgp1"
/note="conserved polymerase motif C; other site"
/db_xref="CDD:438025"
mat_peptide 8577..9521
/locus_tag="PlPVgp1"
/product="coat protein"
/protein_id="NP_734348.1"
misc_feature 8817..9515
/locus_tag="PlPVgp1"
/note="Potyvirus coat protein; Region: Poty_coat;
pfam00767"
/db_xref="CDD:279151"
gene <2912..3208
/locus_tag="PlPVgp2"
/db_xref="GeneID:12983948"
CDS <2912..3208
/locus_tag="PlPVgp2"
/codon_start=1
/product="PIPO"
/protein_id="YP_006393317.1"
/db_xref="GeneID:12983948"
/translation="KLSPGIGASLERVKLVGKILCNLGIAAMAKTYTKTFHPKRRRRF
RRQVRHLRSVITWQPVQTPERRSPMEKRRCGLLYIPVDGEAILQSHRNLTKFSS"
regulatory 9649..9653
/regulatory_class="polyA_signal_sequence"
ORIGIN
1 aaaatataaa aactcaacac aacatacaaa attttatgca atcaaatcaa tctcaagcta
61 tcaaaatttt tcgaatctca cttgaaagat caaaaatcaa caaagaaaat tccttaattt
121 ctttactaaa tttactgcaa gtcaagatgt caaccattgt atttggctca ttcacttgcc
181 acctcgatgc agctatccac caggataatg cagacagatt ggcaaaggcc tggacccgtc
241 cagagaaccg ccaagtcagt aacgcgcatc tactgtgccg aagagcggca gaaagtctca
301 taaacacata tgagagtgca acagctagtg cttggaaagg gctggaagag aagttgcagc
361 ctatgtttgc taagcgtgag tttagcaaaa cagtcacaaa gagaaaaggg cttcggtgct
421 tcaaagaaag ctctgagaag tttattgaga agaagctcag gaaacagtat caagaggagc
481 gtgagagact ccaattcctc aacggtccgg atgcaatagt caaccaaatc agtgttgaca
541 aatgtgaagc ttcagtacgg gtaccatccc ctcatattat tgagaaacct agctttgtaa
601 caccatcaat gaaaaagaag gtggtgttta agaaggttag gatgtccgag gcatcactac
661 aactttttat gaggagggtt gctgcaaacg ccaaggcaaa tggacaaaaa gttgagatca
721 tagggcgtaa gcgtgtagtc ggtaactaca caacgaaaag tcgcctgaca tactttcgca
781 cacatgttcg gcacttggat ggttcaaaac cacgctatga tcttgtgttg gacgaggcaa
841 ccaagaagat tctgcaactg tttgcaaaca caagcggttt ccaccatgtc cataagaaag
901 gggaggtaac accaggaatg agcggatttg tggtaaatcc catgaatcta tcggacccaa
961 tgcaagtgta tgacacggat ctttttatag ttcgtggaaa acacaactct attcttgttg
1021 actcacggtg taaggtttct aaaaagcaga gcaatgagat aatccactac tcagacccag
1081 gcaaacaatt ttcggatggt ttcaccaatt catttatgca gtgcaagcta cgcgaaactg
1141 atcatcagtg cacatctgac ctggacgtga aggagtgtgg ttatgtcgca gcacttgtgt
1201 gccaagcgat aatcccttgc ggaaaaatca cgtgtctgca atgtgctcaa aagtattctt
1261 acatgtcaca acaggaaata cgtgatagat tttcgacagt aattgagcag catgagaaaa
1321 cagtgatgga taactatcca caattttcac atgttctcgc ttttctaaag agatatcgtg
1381 aactaatgcg cgtggaaaat cagaattatg aagctttcaa ggatatcacg cacatgatag
1441 gcgagcgtaa agaagcacct ttttcccatc tcaacaaaat caatgaatta atcattaagg
1501 gtggtatgat gagcgcacaa gactatatag aagcctcgga tcatctacgc gaactagcgc
1561 gatatcagaa gaatcgcacg gagaacatta ggagcggatc tataaaggct ttcaggaata
1621 aaatctcatc aaaagcacat gtcaatatgc agcttatgtg tgacaatcaa cttgatacta
1681 atggcaattt cgtgtgggga cagagagagt atcatgctaa acgcttcttt aggaattact
1741 tcgatgtgat cgatgttagc gagggctaca gacgtcatat tgttcgtgaa aatcctagag
1801 gtatccgcaa attggccatt ggcaaccttg ttatgtcaac aaatctggca gcactacgta
1861 agcagctctt gggtgaagag tgcattcatt ttgaggtctc aaaggaatgc actagcaagc
1921 gaggggaaaa ctttgtatac caatgttgct gtgtcacaca cgaagacggc acaccactgg
1981 agtctgaaat aataagtcca acaaagaatc atttagttgt tggtaactca ggtgattcga
2041 agtatgtgga tttgcccaca gcaaaaggag gtgcaatgtt catagcaaag gcaggttatt
2101 gttacattaa cattttcctt gctatgctga tcaacataaa tgaagatgaa gcaaaaagtt
2161 tcacaaagac agtgcgtgac actcttgtac ctaagcttgg aacatggcca tcgatgatgg
2221 acttagctac agcttgccac tttctcgcag ttctctatcc agaaactcgg aatgctgagc
2281 ttccacgaat actcgttgat cacgaagcaa aaatctttca tgtagttgac tcattcggat
2341 cactgtcaac tggaatgcat gttttgaaag cgaacacaat caatcagctt attagctttg
2401 ctagtgatac attggattca aatatgaaaa catacctggt tggaggtctt gaagtggata
2461 agtgtgacga attcaaaaat gtaaagctct tgatcagaag catttacaag ccacaaatca
2521 tggaacaggt gcttaaggaa gaaccatatt tactgctcat gagcgttttg tcacctggcg
2581 tcttgatggc gctgttcaat agtggttcat tggagaaagc cacacaatat tggatcacac
2641 gatctcatag cttggcagcg atcacatcaa tgttatcagc acttgcagcc aaagtttcac
2701 tcgcaagtac actgaatgca cagatgagtg tcattgacga acatgcagca gttctatatg
2761 atagtgtttt tgttggaacg cagccatacg catcctacat gatggcagtg aaaactttgg
2821 aaaggatgaa agcacggacg gaatccgatc acactttaaa tgacttagga ttctcagtac
2881 tcagacaggc aacaccccac ttggtagaaa aaagttatct ccaggaattg gagcaagctt
2941 ggaaagagtt aagctggtcg gaaaaattct ctgcaatctt ggaatcgcag cgatggcgaa
3001 aacatatacc aaaacctttc atcccaaaag acggcgcaga tttaggaggc aggtacgaca
3061 tctccgttcg gtcattactt ggcaaccagt acaaacgcct gagagacgta gtccgatgga
3121 aaagagacga tgtggtttgc tatacatacc agtcgatggg gaagctattt tgcaaagcca
3181 tcggaatctc accaagtttt cttcctagca ctctcaaaat gcttgacatg ctcatcgtgt
3241 tcagtctctt gctttcaata ggagccacgt gcaactcaat ggtcaatgag cataaacatc
3301 ttaagcaact tgccgccgat cgggaagata agaaaagatt caaaagattg caagtcttat
3361 acacgaggtt atcagagaaa gttggttgca caccaacagc agatgaattc ctggagtatg
3421 tgggagatga aaaccctgat ttactgaaac atgcagagga tctgattggg gatggtcaag
3481 ttgttgttca tcaaagtaag agagactcac aagcaaattt ggaacgggtt gtagcatttg
3541 tagctctcgt tatgatgctg tttgactcgg agcgaagtga cggcgtgtac aagattctca
3601 ataaactcaa aggcattatg ggaagtgtcg accgggctgt tcatcatcag agcttggacg
3661 atatagaaga catactggat gagaagaagc tcacagtcga ttttgtactg caaagtaacg
3721 aagttgcacc aactgtccca tttgactcaa cttttgagaa atggtggatg aatcaacttg
3781 agacaggaaa tgtgattcca cactacagga ctgaaggaca tttccttgaa ttcacacgag
3841 aaaatgcagc gcacattgcg aatgaagtca tgcatggctc acatcaagat atcttaattc
3901 gtggagcagt tggatcgggc aaatcaactg gattgccatt ccacttaagc aagaagggcc
3961 acgtcctgct aattgaaccc accaggccgc tagctgagaa tgtgtgcaag cagttgcgag
4021 gtcaaccatt caatgtcaat cctacactgc gcatgcgtgg gatgagcacc tttggatcaa
4081 ctccaatcac tgtgatgaca agcggttacg cactgcactt cttggcaaac aatccaactt
4141 atttggacaa ctataagtgc atcatttttg atgaatgtca cgtgcatgat gcatcagcaa
4201 tggcatttag atgtcttctt tcggagtatt catacccggg aaagatactg aaggtctcag
4261 cgacaccccc tggacatgaa gttgaattca aaacacagaa ggaggtgaag gtcattgttg
4321 aggaatcttt gtcattccag cagtttgttt ccaatctcgg cacaggttgc aatagcgata
4381 ttctcaagca tggggtcaat gtgttggtct atgtcgcaag ttacaatgag gttgacacac
4441 taagcaaatt gctcacagac aggagcttca aagtttcaaa agtcgatggg cgaactatga
4501 aagtcggcaa tgttgagata ccaacgagtg gcactcaggc caaaccgcat ttcgtggttg
4561 caacaaatat cattgaaaat ggagtcacat tggacattga tgtggttgtg gacttcggtt
4621 tgaaagtcgt gcctgtattg gacattgaca atcgtctcgt tcgatacacg aagaagagca
4681 tcagttatgg agaaaggatt caaagattgg ggcgagttgg tcgaaacaaa ccaggagcag
4741 cacttcgtat tggatttaca gagaaaggac tcactcaaat acctccaata atcgcaacag
4801 aagcagcttt tctatgtttc acttatggtt tgccagttat gactaacggt gtgtcaacga
4861 gcttactagc gatgtgcact gtcaagcaag cacggacgat gcaacagttt gaattatccc
4921 cgttctacac agtggcgttg gttcgatttg acgggacaat gcaccaggaa atttttcgat
4981 tgctcaagag ctatagactg cgtgactcag aggtaatctt aaacaagttg gctataccaa
5041 acagcaacgt atgtgggtgg atgagtgttc gtgactacaa acgacaaggc tgtaacttgg
5101 acttggatga aaacattcgt gtaccgtttt acgtgaaaga catccctgaa actttgcacg
5161 agagaatatg gcaagcggta gaaacccaca aatctgatgc aggattcgga aggatctgta
5221 gttcgagtgc gtgcaaaatt gcgtatacgt tacagacaga catccactcc attcctcgga
5281 caattaaaat catcgacgca ctgttggagc aagagagaac aaagcaagca cacttcagag
5341 ctatgaccag tcaatcctgc tcaagttcaa atttctctct gtcaagcatc acctcagcca
5401 ttcgctcaaa atacgccaaa gaccatacgg aagaaaacat tggtgttctc caaatggcga
5461 agtctcagtt gctagaattc aagaacctga acattgatcc aagttatcct gaacttatcc
5521 gcaactttgg cgccttagaa tgtgtgcacc atcaaacaaa ggaaggagtt tcaaaggcgc
5581 tacaacttaa ggggcattgg aataaacgac tcatcactcg tgacgcaaca ttaatgcttg
5641 gagttcttgg tggaggggca tggatgattt tcagttattt gagggatagc ttcaaagaag
5701 aagttattca ccaaggtttc aatcgtaggc aaagacaaaa attgaaattc aggcaagccc
5761 gagataacag aatggccagg gaagtgtatg gtgacgattc aactatggag gcatactttg
5821 gttctgcata ctcaaagaaa ggaaagagca aaggaaagac tagagggatg ggaacgaaaa
5881 cacgcaaatt tgtgaacatg tacgggtacg atcctacaga ctacaacttt gttcgctttg
5941 ttgatccatt gactggtcac accctggacg aaagtcctct tatggacatc aacttggtgc
6001 aggaacactt ctcgcagatt cgcaatgatt acatcggaga tgacaaaatc accatgcagc
6061 acataatgtc aaatccaggt attgtcgcat actatatcaa ggatgcgacg cagaaagccc
6121 tcaaggtgga cctcactcca cacaacccat tgcgtgtatg tgacaaaact gcaactattg
6181 caggatttcc agagagagag tttgaattga ggcagacagg acacccagtt tttgttgaac
6241 ctaatgcaat cccaaagatc aatgaagagg gggacgaaga agttgaccac gaaagtaaat
6301 cactgtttag aggcctgaga gactacaatc caatcgcaag ctcgatatgc caattgaata
6361 actcatctgg tgctagacaa agtgaaatgt ttggacttgg ctttgggggt ttaattgtca
6421 cgaatcagca tttgttcaaa aggaatgacg gagagctaac aatccgatcg catcatgggg
6481 aattcgtagt gaaggacaca aaaactctca aactgcttcc ttgcaaaggt cgggacatag
6541 tgatcatcag attaccaaag gacttccctc cttttccgag gaggttgcag ttccgcaccc
6601 cgacgactga ggacagagtt tgtttaattg gttcaaattt ccaaacgaag agcatttcaa
6661 gcaccatgtc ggaaacaagc gcaacatatc cagttgataa cagtcatttc tggaaacact
6721 ggattagtac gaaggatggt cattgcggat tacccatcgt gagcactcga gatggcagta
6781 ttcttgggct acacagtctt gcaaattcaa cgaacaccca gaatttctat gcagctttcc
6841 ctgacaactt cgagaccaca tacttgtcaa atcaagacaa tgataactgg ataaagcagt
6901 ggcgatacaa tccggatgaa gtttgctggg gatccctaca gctcaagagg gacattccac
6961 agagtccgtt tacaatttgt aaactgctaa cggatcttga tggggaattt gtttacactc
7021 agtccaaaac tacacattgg ctcagagata gattagaagg aaatttgaaa gcagttggag
7081 cctgccctgg gcagttggtt actaagcatg tcgttaaagg caaatgtaca ctctttgaaa
7141 catacctgtt gactcatcca gaggagcacg aattctttcg acctttaatg ggagcatacc
7201 aaaagagtgc tctaaataag gacgcatacg tcaaagatct gatgaagtat tcaaaaccaa
7261 tcgtcgttgg tgcagttgac tgtgatcaat ttgaacgtgc tgttgatgtg gtcatctcga
7321 tgctaatttc caaaggtttt gaagaatgta attacgtcac tgatccagat gacatattct
7381 cagcacttaa catgaaagca gcagttggcg ctttgtacag tggaaagaaa agggactatt
7441 ttgagaacgt gtcagaccag gacaaggaaa gtttcgtgcg agctagttgc aaacgtttgt
7501 tcatgggaaa gaaaggagtg tggaatggct ctttgaaggc agaattgcgc cctaaagaga
7561 aggtagaggc taataaaact cgatcattca cagcagcacc gattgatacc cttctggggg
7621 gaaaagtgtg cgttgatgac ttcaataatc agttttacag cctgaattta cattgtccat
7681 ggagcgttgg gatgacaaaa ttcagaggtg gttgggacaa actgcttaaa gcactgccag
7741 aaggatggat ttactgtgat gccgatggct ctcaatttga cagttccctc tcaccgtact
7801 taatcaatgc agttctcaat attcgtctgg catttatgga agaatgggac attggtgaac
7861 aaatgctttc aaacctgtat acggagattg tatatacacc aattgctaca ccagatggca
7921 ctattgttaa gaagttcaag ggaaacaata gtggtcaacc ctcgacagtt gttgacaata
7981 cactcatggt tattttggca atgacatatt cactccttaa gcttggacac catccggata
8041 cacacgattg catttgtcgg tactttgtga atggtgatga tcttgtcctc gcagtgcacc
8101 cagcatacga gagcatttat gatgagcttc aagaacactt ttcccaactt ggattgaatt
8161 acacattcac cacaaagact gaaaacaagg aagagctgtg gtttatgtca cataaaggcg
8221 ttctctacga tgacatgtac attcccaagc tggagcctga gaggattgta tcaatacttg
8281 aatgggacag atcaaatgag ccaatccatc gattggaggc aatttgtgca tcaatggtgg
8341 aagcgtgggg ttataaggag ctgctgaggg agatccgaaa attttacagt tgggttcttg
8401 aacaagcacc atacaatgct ctttcaaaag atggaaaagc cccgtacatt gcggagacag
8461 cactgaagaa gctttacact gacactgaag catccgagac agaaattgag cgatatcttg
8521 aagcttttta cgacaacatt aacgatgatg gtgagtccaa cgttgttgtg caccaagctg
8581 acgaaagaga agacgaggag gaagttgatg cacttcaacc acctccagtc atacagcctg
8641 caccccggac tacggcgcca atgctcaacc ccattttcac gccagcaaca actcaaccag
8701 caacaaaacc agtttcacag gtgtcaggac ctcaactgca aacttttgga acatatagtc
8761 atgaggatgc atcacctagc aactcaaacg cgctagtcaa cacaaacaga gacagggatg
8821 tcgatgcagg atcaactgga acttttacag tgccacgttt gaaggcaatg acttcgaaac
8881 tatctctgcc aaaggtgaag ggaaaggcta ttatgaactt gaaccatttg gcacattata
8941 gtcctgcaca ggttgacttg tcaaacacga gagctccgca gtcttgtttc caaacttggt
9001 atgaaggagt taagcgagac tatgatgtca cggacgatga aatgagcatc attttaaatg
9061 gtcttatggt ttggtgcata gagaatggaa catccccgaa tatcaatgga atgtgggtga
9121 tgatggatgg ggaaacacaa gtggagtatc caataaagcc attgttggat catgcgaaac
9181 ccacttttag acaaattatg gcacatttca gtaacgtggc tgaagcgtat attgaaaaac
9241 gaaattatga aaaagcatac atgccaaggt atggaattca gcgcaacctg acagactaca
9301 gcctcgccag atatgccttt gatttttacg aaatgacttc aacgacaccc gtacgggcac
9361 gtgaagctca tatccaaatg aaggcagcag cattgagaaa tgttcaaaat cgtttatttg
9421 gcttggatgg aaacgtcgga acacaagaag aggacacaga gagacacacc gctggtgatg
9481 ttaatcgcaa catgcacaac ctcctcggta tgaggggagt gtagtggtct cggtatctat
9541 cataaactct acctgggtga gagtctaacc atccagttgt ttttagattc ctgttagcat
9601 ccttttctcc gctttaatag cagtacattc agtgaggttt tacctccata tgtgctagtc
9661 tgttattgtc gaacacaggc ccttgtatct gatgtagcga gtgtttcact ccattcgggt
9721 tatagttctt gtgcaagaga c
//
