LOCUS       NC_004178               3183 bp ds-RNA     linear   VRL 13-AUG-2018
DEFINITION  Infectious bursal disease virus segment A, complete sequence.
ACCESSION   NC_004178
VERSION     NC_004178.1
DBLINK      BioProject: PRJNA485481
KEYWORDS    RefSeq; VP2-4-3 polyprotein; VP5 protein.
SOURCE      Infectious bursal disease virus (Gumboro virus)
  ORGANISM  Infectious bursal disease virus
            Viruses; Riboviria; Orthornavirae; Birnaviridae; Avibirnavirus;
            Avibirnavirus gumboroense.
REFERENCE   1  (bases 1 to 3183)
  AUTHORS   Brown,M.D. and Skinner,M.A.
  TITLE     Coding sequences of both genome segments of a European 'very
            virulent' infectious bursal disease virus
  JOURNAL   Virus Res. 40 (1), 1-15 (1996)
   PUBMED   8725117
REFERENCE   2  (bases 1 to 3183)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2004) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 3183)
  AUTHORS   Skinner,M.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-NOV-1995) M.A. Skinner, Institute for Animal Health,
            Compton Laboratory, Near Newbury, Berkshire, RG20 7NN, UK
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from X92760.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..3183
                     /organism="Infectious bursal disease virus"
                     /mol_type="genomic RNA"
                     /strain="Very virulent strain"
                     /isolate="UK661"
                     /db_xref="taxon:10995"
                     /segment="A"
                     /lab_host="Gallus gallus (light Sussex)"
                     /note="serotype: I"
     gene            84..533
                     /locus_tag="IBDVsAgp1"
                     /db_xref="GeneID:956508"
     CDS             84..533
                     /locus_tag="IBDVsAgp1"
                     /codon_start=1
                     /product="VP5 protein"
                     /protein_id="NP_690837.1"
                     /db_xref="UniProtKB/TrEMBL:Q82634"
                     /db_xref="GeneID:956508"
                     /translation="MLSLMVSRDQTNDRSDDKPARSNPTDCSVHTEPSDANNRTGVHS
                     GRHPREAHSQVRDLDLQFDCGGHRVRANCLFPWLPWLNCGCSLHTAEQWELQVRSDAP
                     DCPEPTGQLQLLQASESESHSEVKHTPWWRLCTKWHHKRRDLPRKPE"
     misc_feature    126..530
                     /locus_tag="IBDVsAgp1"
                     /note="Birnavirus VP5 protein; Region: Birna_VP5;
                     pfam03042"
                     /db_xref="CDD:281092"
     gene            130..3168
                     /locus_tag="IBDVsAgp2"
                     /db_xref="GeneID:956509"
     CDS             130..3168
                     /locus_tag="IBDVsAgp2"
                     /codon_start=1
                     /product="VP2-4-3 polyprotein"
                     /protein_id="NP_690838.1"
                     /db_xref="UniProtKB/TrEMBL:Q82635"
                     /db_xref="GeneID:956509"
                     /translation="MTNLQDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETST
                     YNLTVGDTGSGLIVFFPGFPGSIVGAHYTLQSNGNYKFDQMLLTAQNLPASYNYCRLV
                     SRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLV
                     GEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSS
                     QYQAGGVTITLFSANIDAITSLSIGGELVFQTSVQGLILGATIYLIGFDGTAVITRAV
                     AADNGLTAGTDNLMPFNIVIPTSEITQPITSIKLEIVTSKSGGQAGDQMSWSASGSLA
                     VTIHGGNYPGALRPVTLVAYERVATGSVVTVAGVSNFELIPNPELAKNLVTEYGRFDP
                     GAMNYTKLILSERDRLGIKTVWPTREYTDFREYFMEVADLNSPLKIAGAFGFKDIIRA
                     LRRIAVPVVSTLFPPAAPLAHAIGEGVDYLLGDEAQAASGTARAASGKARAASGRIRQ
                     LTLAADKGYEVVANLFQVPQNPVVDGILASPGILRGAHNLDCVLREGATLFPVVITTV
                     EDAMTPKALNSKMFAVIEGVREDLQPPSQRGSFIRTLSGHRVYGYAPDGVLPLETGRV
                     YTVVPIDGVWDDSIMLSKDPIPPIVGSSGNLAIAYMDVFRPKVPIHVAMTGALNAYGE
                     IENVSFRSTKLATAHRLGLKLAGPGAFDVNTGSNWATFIKRFPHNPRDWDRLPYLNLP
                     YLPPNAGRQYDLAMAASEFKETPELESAVRAMEAAANVDPLFQSALSVFMWLEENGIV
                     TDMANFALSDPNAHRMRNFLANAPQAGSKSQRAKYGTAGYGVEARGPTPEGAQREKDT
                     RISKKMETMGIYFATPEWVALNGHRGPSPGQLKYWQNTREIPDPNEDYLDYVHAEKSR
                     LASEGQILRAATSIYGAPGQAEPPQAFIDEVAKVYEVNHGRGPNQEQMKDLLLTAMEM
                     KHRNPRRAPPKPKPKPNVPTQRPPGRLGRWIRAVSDEDLE"
     misc_feature    154..1485
                     /locus_tag="IBDVsAgp2"
                     /note="Birnavirus VP2 protein; Region: Birna_VP2;
                     pfam01766"
                     /db_xref="CDD:280020"
     misc_feature    1489..2295
                     /locus_tag="IBDVsAgp2"
                     /note="Birnavirus VP4 protein; Region: Birna_VP4;
                     pfam01768"
                     /db_xref="CDD:280022"
     misc_feature    2347..3051
                     /locus_tag="IBDVsAgp2"
                     /note="Birnavirus VP3 protein; Region: Birna_VP3;
                     pfam01767"
                     /db_xref="CDD:426418"
ORIGIN      
        1 gatacgatcg gtctgacccc gggggagtca ccctgggaca ggctggcaag gccttgttcc
       61 aggatggaac tcctccttct acaatgctat cattgatggt tagtagagat cagacaaacg
      121 atcgcagcga tgacaaacct gcaagatcaa acccaacaga ttgttccgtt catacggagc
      181 cttctgatgc caacaaccgg accggcgtcc attccggacg acaccctaga gaagcacact
      241 ctcaggtcag agacctcgac ctacaatttg actgtggggg acacagggtc agggctaatt
      301 gtctttttcc ctggcttccc tggctcaatt gtgggtgctc actacacact gcagagcaat
      361 gggaactaca agttcgatca gatgctcctg actgcccaga acctaccggc cagctacaac
      421 tactgcaggc tagtgagtcg gagtctcaca gtgaggtcaa gcacactccc tggtggcgtt
      481 tatgcactaa atggcaccat aaacgccgtg accttccaag gaagcctgag tgaactgaca
      541 gatgttagct acaatgggtt gatgtctgca acagccaaca tcaacgacaa aatcgggaac
      601 gtcctagtag gggaaggggt aaccgtcctc agcttaccca catcatatga tcttgggtat
      661 gtgagactcg gtgaccccat tcccgctata gggctcgacc caaaaatggt agcaacatgt
      721 gacagcagtg acaggcccag agtctacacc ataactgcag ccgacgatta ccaattctca
      781 tcacagtacc aagcaggtgg ggtaacaatc acactgttct cagctaatat cgatgccatc
      841 acaagcctca gcatcggggg agaactcgtg tttcaaacaa gcgtccaagg ccttatactg
      901 ggtgctacca tctaccttat aggctttgat gggactgcgg taatcaccag agctgtggcc
      961 gcagacaatg ggctgacggc cggcactgac aaccttatgc cattcaatat tgtgattcca
     1021 accagcgaga taacccagcc aatcacatcc atcaaactgg agatagtaac ctccaaaagt
     1081 ggtggtcagg cgggggatca gatgtcatgg tcagcaagtg ggagcctagc agtgacgatc
     1141 cacggtggca actatccagg ggccctccgt cccgtcacac tagtagccta cgaaagagtg
     1201 gcaacaggat ctgtcgttac ggtcgccggg gtgagcaact tcgagctgat cccaaatcct
     1261 gaactagcaa agaacctggt cacagaatac ggccgatttg acccaggagc catgaactac
     1321 acaaaattga tactgagtga gagggaccgt cttggcatca agaccgtatg gccaacaagg
     1381 gagtacactg actttcgcga gtacttcatg gaggtggccg acctcaactc tcccctgaag
     1441 attgcaggag catttggctt caaagacata atccgggccc taaggaggat agctgtgccg
     1501 gtggtctcta cactgttccc acccgccgct cccctagccc atgcaattgg ggaaggtgta
     1561 gactacctgc tgggcgatga ggcacaggct gcttcaggaa ctgctcgagc cgcgtcagga
     1621 aaagcaagag ctgcctcagg ccgcataagg cagctaactc tcgccgccga caaggggtac
     1681 gaggtagtcg cgaatctgtt ccaggtgccc cagaatcctg tagtcgacgg gattctcgct
     1741 tcacccggga tactccgcgg tgcacacaac ctcgactgcg tgttgagaga gggtgccacg
     1801 ctattccctg tggtcatcac gacagtggaa gatgccatga cacccaaagc actgaacagc
     1861 aaaatgtttg ctgtcattga aggcgtgcga gaagatctcc aacctccatc tcaaagagga
     1921 tccttcatac gaactctctc cggacataga gtctatggat atgctccaga tggggtactt
     1981 ccactggaga ctgggagagt ttacaccgtg gtcccaatag atggtgtctg ggacgacagc
     2041 attatgctgt ccaaagaccc catacctcct attgtgggaa gcagcggaaa cctagccata
     2101 gcttacatgg atgtgtttcg acccaaagtc cccatccatg tggccatgac aggagccctc
     2161 aacgcctatg gcgagattga gaatgtgagc tttagaagca ccaagctcgc cactgcacac
     2221 cgacttggcc tcaagttggc tggtcccggt gcatttgacg tgaacaccgg gtccaactgg
     2281 gcgacgttta tcaaacgttt tcctcacaat ccacgcgact gggacaggct cccctacctc
     2341 aaccttccat accttccacc caatgcagga cgccagtacg acctggccat ggccgcttca
     2401 gagttcaaag agacccccga actcgagagc gccgtcagag ccatggaagc agcagccaac
     2461 gtggacccac tgttccaatc tgcgctcagc gtgttcatgt ggctggaaga gaatgggatt
     2521 gtgactgata tggccaactt cgcactcagc gacccgaacg cccatcggat gcgcaatttt
     2581 ctcgcaaacg caccacaagc aggcagcaag tcgcaaagag ccaagtacgg gacagcaggc
     2641 tacggagtgg aggcccgggg ccccactcca gagggagcac agagggaaaa agacacacgg
     2701 atctcaaaga agatggagac tatgggcatc tactttgcaa caccagaatg ggtagcactc
     2761 aatgggcacc gggggccaag ccccggccag ctgaagtact ggcagaacac acgagaaata
     2821 cctgatccaa acgaggacta cctagactac gtgcatgcag agaagagccg gttggcgtca
     2881 gaaggacaaa tcctaagggc agctacgtcg atctacgggg ctccaggaca ggcagagcca
     2941 ccccaagcct tcatagacga agtcgccaaa gtctatgaag tcaaccatgg gcgtggcccc
     3001 aaccaagaac agatgaaaga tctgctcttg actgcgatgg agatgaagca tcgcaatccc
     3061 aggcgggccc caccaaagcc caagccaaaa cccaatgttc caacacagag accccctggt
     3121 cggttgggcc gctggatcag ggctgtctct gatgaggacc ttgagtgagg ctcctgggag
     3181 tct
//