LOCUS NC_004366 4152 bp ss-RNA linear VRL 13-AUG-2018
DEFINITION Tobacco bushy top virus, complete genome.
ACCESSION NC_004366
VERSION NC_004366.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Tobacco bushy top virus (TBTV)
ORGANISM Tobacco bushy top virus
Viruses; Riboviria; Orthornavirae; Kitrinoviricota;
Tolucaviricetes; Tolivirales; Tombusviridae; Calvusvirinae;
Umbravirus; Umbravirus nicotianae.
REFERENCE 1 (bases 1 to 4152)
AUTHORS Mo,X.H., Qin,X.Y., Wu,J., Yang,C., Wu,J.Y., Duan,Y.Q., Li,T.F. and
Chen,H.R.
TITLE Complete nucleotide sequence and genome organization of a Chinese
isolate of tobacco bushy top virus
JOURNAL Arch. Virol. 148 (2), 389-397 (2003)
PUBMED 12557001
REFERENCE 2 (bases 1 to 4152)
AUTHORS Mo,X., Qin,X., Tan,Z., Li,T., Wu,J. and Chen,H.
TITLE First Report of Tobacco Bushy Top Disease in China
JOURNAL Plant Dis. 86, 74 (2002)
REFERENCE 3 (bases 1 to 4152)
AUTHORS Mo,X., Qin,X., Wu,J., Li,T. and Chen,H.
TITLE Direct Submission
JOURNAL Submitted (30-JUN-2015) Biotechnology Lab., Yunnan Academy of
Tobacco Science, Keyi Road, Kunming City, Yunnan Province 650106,
P.R. China
REMARK Amino acid sequence updated by submitter
REFERENCE 4 (bases 1 to 4152)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2002) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (bases 1 to 4152)
AUTHORS Mo,X., Qin,X., Wu,J., Li,T. and Chen,H.
TITLE Direct Submission
JOURNAL Submitted (19-APR-2002) Biotechnology Lab., Yunnan Academy of
Tobacco Science, Keyi Road, Kunming City, Yunnan Province 650106,
P.R. China
REMARK Sequence update by submitter
REFERENCE 6 (bases 1 to 4152)
AUTHORS Mo,X., Qin,X., Wu,J., Li,T. and Chen,H.
TITLE Direct Submission
JOURNAL Submitted (25-JUL-2001) Biotechnology Lab., Yunnan Academy of
Tobacco Science, Keyi Road, Kunming City, Yunnan Province 650106,
P.R. China
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence is identical to
AF402620.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..4152
/organism="Tobacco bushy top virus"
/mol_type="genomic RNA"
/isolate="Ch"
/db_xref="taxon:184020"
/country="China"
gene 11..2607
/locus_tag="TBTVgp2"
/db_xref="GeneID:955935"
CDS join(11..952,952..2607)
/locus_tag="TBTVgp2"
/ribosomal_slippage
/note="orf1-fs"
/codon_start=1
/product="RNA-dependent RNA polymerase"
/protein_id="NP_733848.2"
/db_xref="GeneID:955935"
/translation="MEFINKIKQLLAMNFKPSKGVMSREELREAFDPTWELLITQARV
TNEVSRQCEDWYTLAVPTTYRLPELAVEEAVREKNIAREVAVKCPPEDPIPAIPQGSQ
PVPLVMSSERSSQDAEREALDEIWGLPTPESHPLPKYFERRYQALARTCEKDYSNWQI
VPYTGGPRVLREEDVLPMASGVIPLPPPPPKASVIGAVLGLITRLTKVAGEVKSRLSV
PPREPSPTCIGLEQVAGEPMGYMNAHSVAMELRARYGVQPATAANLQLGNRVAREILE
KQCGATRDMVFILGHLATTLWFTPTMVDLALQCGPKDFLLGDVVARRGVETKVKTKIH
PKIRVLRAARPRPVERVSYQIDVVRPCADFGVHNNSLNNLVRGVNERVFYTDHKRKEP
RRPSAGSFDKIDISEIKAFRVQPWTLEEVVDSYTGSQRVRYGQAVESLAVTPLSRNDA
RVKTFVKAEKINFTAKPDPAPRVIQPRDPRFNACFAKYTKPLEPLLYKQLGKLYQFPC
IAKGFNAVETGEIVAKKWKCFSDPVCVGLDASRFDQHVSCDALRFTHSVYKRFVKGRE
VNKLLSWMYKNHALGSAKDGFVKYEVEGCRMSGDMDTALGNCVLMVLMTRQLCKNLSI
PHELMNNGDDCIVIFDRQYLSTFQDAVEPWFRELGFTMKVEEPVYHLERVDFCQTRPV
YDGKKWRMVRHISSIAKDCCSVIDWEQLPAWWNAIGECGIAVAGGIPIHNSFLRWLLR
SGESNPDLLKHGAWKNEGLAWYRMGMDLSHERHVSDEARASFHTAFGIEPSMQVALEQ
IYDSLPAPTIGGKRARVCKPGEMVLVDSLPPRHFNDYFQDVGIGGSSSDYVVPGTHEF
EPGTLWTQC"
misc_feature 1012..2427
/locus_tag="TBTVgp2"
/note="catalytic core domain of RNA-dependent RNA
polymerase (RdRp) in the subfamily Calvusvirinae of
positive-sense single-stranded RNA [(+)ssRNA] viruses;
Region: Calvusvirinae_RdRp; cd23234"
/db_xref="CDD:438084"
misc_feature 1606..1650
/locus_tag="TBTVgp2"
/note="conserved polymerase motif A; other site"
/db_xref="CDD:438084"
misc_feature 1795..1866
/locus_tag="TBTVgp2"
/note="conserved polymerase motif B; other site"
/db_xref="CDD:438084"
misc_feature 1885..1929
/locus_tag="TBTVgp2"
/note="conserved polymerase motif C; other site"
/db_xref="CDD:438084"
gene 11..958
/locus_tag="TBTVgp1"
/db_xref="GeneID:955937"
CDS 11..958
/locus_tag="TBTVgp1"
/note="orf1"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_733847.1"
/db_xref="GeneID:955937"
/translation="MEFINKIKQLLAMNFKPSKGVMSREELREAFDPTWELLITQARV
TNEVSRQCEDWYTLAVPTTYRLPELAVEEAVREKNIAREVAVKCPPEDPIPAIPQGSQ
PVPLVMSSERSSQDAEREALDEIWGLPTPESHPLPKYFERRYQALARTCEKDYSNWQI
VPYTGGPRVLREEDVLPMASGVIPLPPPPPKASVIGAVLGLITRLTKVAGEVKSRLSV
PPREPSPTCIGLEQVAGEPMGYMNAHSVAMELRARYGVQPATAANLQLGNRVAREILE
KQCGATRDMVFILGHLATTLWFTPTMVDLALQCGPKDFC"
gene 2757..3470
/locus_tag="TBTVgp3"
/db_xref="GeneID:955934"
CDS 2757..3470
/locus_tag="TBTVgp3"
/note="orf3"
/codon_start=1
/product="hypothetical protein"
/protein_id="NP_733849.1"
/db_xref="GeneID:955934"
/translation="MSTIINVNTHPQGRYERGAAQRSIRGSDVKGARGIKPRRSNPPS
GRKQGGNDPTAATQKSRKNRQRPETVPPHETHGGTFIHREGCGGVHAPHPGRCWRRGR
NLGPRQHATTPKQRWAPRKISDERRAQVDSILSPLLDTLKLSSEGGAPELLHCIGVLR
RELRRRREPVQPVHNVGTEDRVRSAQLSDEAPQSNANLQTSGEGQSVLPNPDSGGTEK
CNVESVCNNCDRAPTTNKW"
misc_feature 2757..3443
/locus_tag="TBTVgp3"
/note="Umbravirus long distance movement (LDM) family;
Region: Umbravirus_LDM; pfam04817"
/db_xref="CDD:113583"
gene 2773..3507
/locus_tag="TBTVgp4"
/db_xref="GeneID:955936"
CDS 2773..3507
/locus_tag="TBTVgp4"
/note="orf4"
/codon_start=1
/product="movement protein"
/protein_id="NP_733850.1"
/db_xref="GeneID:955936"
/translation="MSTLIHKADTKEELLNALYGEVTLRELEESNLGVLTPHRAENKV
VMTPLLPPRSQGRIASVLKRFRPTKHTGGLLFIEKVVVVFTPHIPDDAGGEVEIWVHD
NMLPHLNSVGPRVRFPMSGGPRLIAFYPPYSIPLSCQVRGAPRSYFIVSEYSGVNFVA
GASPFSLYIMWEPKIECVAHNYLMRPPKAMPICRHLVKDSLSSLTLTQGALKSAMSNR
YATTATGLPPPTSGEQDMEVVSHPPG"
misc_feature 2791..3396
/locus_tag="TBTVgp4"
/note="3A/RNA2 movement protein family; Region: 3A;
pfam00803"
/db_xref="CDD:279181"
ORIGIN
1 aggttacgat atggagttca tcaacaagat aaagcaattg ttggcaatga atttcaagcc
61 ctcaaagggc gtaatgtctc gggaggagct ccgtgaagct ttcgatccca cttgggagct
121 cctcatcaca caggcccgtg tcaccaatga ggtgtcacgc cagtgtgagg attggtacac
181 tctagctgta cccaccacct accgcttgcc agagttggcg gtagaagagg ctgtgcgtga
241 aaagaacata gcgcgagagg tggcggtcaa gtgcccccct gaggacccga ttcctgcaat
301 cccgcagggg tcacagcctg tccccttggt gatgagctct gaacgctcta gccaggatgc
361 cgagcgtgag gcgctcgatg agatatgggg gctccccact cccgagtcac atcctctgcc
421 caagtacttc gagcggcgct accaggcgct ggctcggacc tgcgagaagg actactccaa
481 ctggcagatt gtaccctaca cgggtgggcc acgcgtgctg agagaggagg acgtgctacc
541 aatggcttcg ggggttatac ccttgccacc acccccccct aaggcttctg taatcggagc
601 agtcttgggg ctgattaccc gccttaccaa ggtggcgggg gaggtgaaga gcaggctgag
661 cgtaccgccg cgggagccct cgcccacttg cattggctta gagcaggtgg ctggtgagcc
721 catgggctac atgaatgcac actctgtggc catggagttg cgggctaggt acggagtcca
781 gcccgccaca gctgcgaact tgcagcttgg aaaccgggtg gccagggaaa tcctggaaaa
841 acagtgcggg gccacccgcg acatggtgtt catactcggg cacctcgcca ccaccttgtg
901 gttcacccct accatggtgg acttggccct tcaatgtggg cccaaggatt tttgctaggg
961 gatgtggtcg ctcggagggg tgtagaaact aaagtgaaga cgaaaatcca ccccaaaatc
1021 cgagtgctta gggcggcccg tccccggccc gtagaaagag tgtcgtacca aatcgacgtg
1081 gtgcggccct gtgctgactt tggagtccac aacaactccc tcaacaattt agtgcgaggg
1141 gttaacgagc gggtgttcta cacagaccac aagaggaaag agccccgcag accttcagct
1201 ggtagttttg acaagattga catcagcgag ataaaagcgt tcagagtcca gccgtggact
1261 ctcgaggagg tcgttgacag ctacacgggt agccagaggg tgcggtatgg acaagctgtt
1321 gaatccttag cagtaacgcc cctctcacga aacgacgccc gggtcaaaac atttgtaaag
1381 gcggaaaaga taaacttcac cgccaagccc gacccggctc ctcgcgtaat ccagccgcgg
1441 gatccaaggt tcaatgcctg ctttgccaaa tacacaaagc ccttggaacc cctcctatac
1501 aagcagctgg gtaagcttta ccagttccca tgcatcgcaa aaggctttaa cgccgtagag
1561 accggagaga tagtagccaa gaagtggaag tgcttcagtg accctgtctg tgtgggttta
1621 gatgcctccc ggtttgacca gcatgtgtca tgcgatgcac tacggttcac ccatagcgtg
1681 tacaaacggt tcgtgaaggg cagggaagtg aacaagttgc tttcctggat gtacaaaaac
1741 cacgctctgg gaagtgcgaa ggacggattc gtcaagtacg aggtggaagg ctgtcggatg
1801 agtggggata tggatacagc cctagggaat tgtgtcctga tggtcctcat gactaggcaa
1861 ctatgcaaga acctctccat accgcacgaa ctgatgaaca acggcgacga ctgcatagtt
1921 atatttgaca ggcagtacct gtccaccttt caggatgcag tcgagccttg gtttagggag
1981 ctagggttta caatgaaggt cgaggagcca gtctaccatc tcgaaagagt agatttttgc
2041 cagacccgcc ccgtgtatga cggcaagaag tggagaatgg tcaggcatat ctcaagtata
2101 gcgaaggatt gctgttcagt cattgactgg gaacagttac cggcttggtg gaacgccatt
2161 ggagaatgtg gcattgccgt ggctggtggt atacccatac acaacagctt cttgagatgg
2221 ctcctgagat caggtgagag caaccctgat ctcctgaagc atggcgcatg gaaaaatgag
2281 ggcctagcgt ggtaccggat gggcatggac ctatcccatg agagacacgt tagtgatgaa
2341 gcgcgcgcca gcttccacac tgcctttgga atcgaaccat ccatgcaggt cgcattagag
2401 cagatctatg actcattgcc tgctcccacc attggtggga aacgagccag agtgtgtaaa
2461 cctggtgaaa tggtattggt tgattcactc ccaccgcggc actttaatga ttacttccag
2521 gatgttggaa taggggggag tagcagtgat tacgttgtcc cggggaccca cgagttcgaa
2581 ccggggacgt tgtggacaca atgctagtca attgagtcag ccaggcatat ggttgcaagc
2641 gctggggact tagtccataa aaccactggt aaagagcctc cagtaggcag gcccgccttg
2701 atgagtctta acgagtggac acccgggtag ccgcggacaa tgcccgacgg gtttcaatgt
2761 ctacgatcat aaatgtcaac actcatccac aaggcagata cgaaagagga gctgctcaac
2821 gctctatacg gggaagtgac gttaagggag ctcgaggaat caaacctcgg cgttctaacc
2881 ccccatcggg ccgaaaacaa ggtggtaatg accccactgc tgccacccag aagtcaagga
2941 agaatcgcca gcgtcctgaa acggttccgc cccacgaaac acacgggggg acttttattc
3001 atagagaagg ttgtggtggt gttcacgccc cacatcccgg acgatgctgg cggagaggta
3061 gaaatctggg tccacgacaa catgctacca cacctaaaca gcgttgggcc ccgcgtaaga
3121 tttccgatga gcggagggcc caggttgata gcattttatc ccccctactc gataccctta
3181 agttgtcaag tgaggggggc gccccggagc tacttcattg tatcggagta ctccggcgtg
3241 aacttcgtcg caggcgcgag cccgttcagc ctgtacataa tgtgggaacc gaagatagag
3301 tgcgtagcgc acaactatct gatgaggccc cccaaagcaa tgccaatttg cagacatctg
3361 gtgaaggaca gtctgtcctc cctaaccctg actcaggggg cactgaaaag tgcaatgtcg
3421 aatcggtatg caacaactgc gaccgggctc ccaccaccaa caagtggtga gcaggatatg
3481 gaggtagtgt cccatcctcc aggctaaatt ggacacaaaa cggagctaga tttagtgttg
3541 caattgctag accgttagcc actacgccag acagtgcgat aactgaggtc gtctatgacc
3601 cacagggtgc catcctgtgc aatttccaac ccttggcagg ggtgatccta gaggacgcgg
3661 gcattgactt gcctggggat gcttctagtt acataccgga gtggttgata gacctctgtg
3721 taaggaaaca ggtgtgagac tggatcctgg gaaacaggct gggatggtcc cgtaagttcg
3781 ggcggtgccc ttcgggggta accccaccgc cgacgtatca cctcacacgc tgttggccga
3841 taagccgagg tgttggaacc gcaccactct ggaggttccc tctccttatg aggtggaggc
3901 acagcacgcc ttaagtgtct gcgatccggc gttcacgtgc cggtggtccc cctagttaac
3961 gtggtgccac agtctgtggt aggggcagct ggtcggattc cagcagaaac caagtagcaa
4021 atggacgttg ctacctcgag cctagagtca tgggcccgca tcgacgtttg cggtaactca
4081 cagcgggcga taatagctgt tgagaatgtc ggttcctgac ttagcgggag atgagcactt
4141 tctctcgcgc cc
//
