LOCUS NC_012038 8542 bp ss-RNA linear VRL 13-AUG-2018
DEFINITION Helleborus net necrosis virus, complete genome.
ACCESSION NC_012038
VERSION NC_012038.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Helleborus net necrosis virus
ORGANISM Helleborus net necrosis virus
Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
REFERENCE 1 (bases 1 to 8542)
AUTHORS Eastwell,K.C., duToit,L.J. and Druffel,K.L.
TITLE Helleborus net necrosis virus: a new Carlavirus associated with
'black death' of Helleborus spp.
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 8542)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (04-FEB-2009) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 8542)
AUTHORS Eastwell,K.C., duToit,L.J. and Druffel,K.L.
TITLE Direct Submission
JOURNAL Submitted (09-SEP-2008) Department of Plant Pathology, Washington
State University, 24106 North Bunn Road, Prosser, WA 99350, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from FJ196835.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..8542
/organism="Helleborus net necrosis virus"
/mol_type="genomic RNA"
/strain="G5"
/isolation_source="Helleborus X hybridus"
/db_xref="taxon:592206"
/country="USA"
5'UTR 1..58
gene 59..5929
/locus_tag="HHNV_gp1"
/db_xref="GeneID:7412081"
CDS 59..5929
/locus_tag="HHNV_gp1"
/note="ORF I"
/codon_start=1
/product="putative replicase polyprotein"
/protein_id="YP_002574614.1"
/db_xref="GeneID:7412081"
/translation="MALTYRSPIENVLTTFTTTEQSSISAPAVKWYKDHEAEHFALFN
YALPESAKQRLWQSGLYLSPFSALPHSHPVCKTLENYMLYTVLPTYVDNTFYFVGIKN
HKLEFLKQRRKHVNLVESLNRYVTSADKFRYPNDFVIARSEEICGLKRHQRFLSNPSL
KTLLPDVVAKSQKNLFFHDEIHYWDYDSLTTFLEIVKPNKLVCTMVYPPELLVGAKES
LNPWCYHFEVQGDSFRFYPDGVRTEGYTQPLAGGNLLKANSIVLADGTTYGVDLLCSK
FAHHLIGLSKGESKFPVDRAFGDFDAVSAEGLKKICARVQGAIPISYGTISRIYRYLR
TLNKPDTQSAMAKLSQLLPEPSGYEIKFVQDFSKLVINTPVTQTMFTNNYCEAMLQSL
IASAPPILGKYFSKFAALTLDKFIEELKPLTFNLKLREYKSTSNCNIDYFDFAADLEP
QTVLQLLDDGFQSSRMFYGERTRALYYCNEPSFSCFDFDDSVLERTLTAYFVNAHGSE
SQVRFSLGRLKHFSCAFLRKCSLTAQACWGVTTEMLLRIRKRVEAILVRFYNFSFFLE
PSVWFAETKRRRSVRYINATDEIPTGLFCRNDLHKSVIGELILKRQARTPAEIPIAPV
NENHTEALTMLELEPDSDSDDGVALPETIQSFTCKCGCILPFFNVIGADLCILPTPDK
LKGRTAGWYSKDGRPYSYNGGAHKSLGWPIWLDTFLELNAHGYGPFDSVLVQEYSNDS
GIGYHADNEEIFKPEGAILTMSIRGSASFGLKCSAGECGFEHLECTSFVMPSGLQQTH
KHRVFGTKGNRISLTFRMLRDSAYLSSDGSDNGLGSDHDEEDHADFTESSETFGVKLD
LRKTHPLNAFKPIEVPADGDCFWHAVGYLIGLNGSEVKKAVAERSKVELKANAELTAQ
MGNKVFAENEAFAAACVLLDISITFIISDEGHSVIFNKEGSTLMLYIKLQNTHCSPLL
PRNDCVIVAGASALSRPVKDVYKVLMRREHSLIFKQLCAGEGLSLMLLGQFFSIFDIH
AYINFEGEHMEVNESGSLKRCFTVEQEHIAHNVKMGCSAIAPTMTGSNNAVSLKSLKV
LKACGTELVYTVEEERARRLADSLHSGTTGAVCSSLFNGTPNLLQGLNPDWEARNVVA
ILGTFGSGKSTLFKDLFKRNPGKLICFVSPRRSLAQEIKESVFGKCTSPDGKFKIVRN
KKNCNFNVCTFETFLKLAKGLKAGHTLVLDEIQLYPPGYLDLVACLVPRSCHLFVVGD
PCQSNYDSEGDRSIFSGAASDIHKMLANAKYKFVTRSRRFFNKTFSGRLPCAMDDSKL
VVSEEYFMARSFEEVRSFSKVFTEVFLVPGFDEKKIIKAHFPNCENILTFGESTGRTF
EYGSILITQSGFSVCEQRWITALSRFSRNLLFLNLTEASFEAIAENMDDRALGKFFTQ
SASIDDLRKILPGEPHFADYYVPKLGKDHCVREDKLAGDPWLKTMVFLGQEEDVEKSE
IEEAILAEPWFKTHLPLCEMESVRASWVQNFKAKENREVRKGYLVSDQFTDEHSKNRG
KILTNAAERFEAIYPRHKNSDTVTFLMAVKKRLRFSKPMVECAKLNEARGYGKYLLDN
FLKFVPLKAQHNPEFMARSVRDFEEKKTSKSAATIENHSGRSCRDWLADVGLIFMKSQ
ICTKFDNRFRVAKAAQSIVCFQHSVLCRFAPYMRYIEMKLQEALPKNFYIHSGKGLEE
LNKWVLGGNFRGICTESDYEAFDASQDQHIVAFELACMEYLGLPKDLIADYCYIKTHL
GSKLGSFAIMRFSGEASTFLFNTMANMLFTFLRYELTGKEFISFAGDDMCASKRLRVS
VEHESFLGKLKLKAKVNFTTNPTFCGWCLTTDGIFKKPQLVFERLCIAKETNNLANCI
DNYAIEISYAYKLGEAAVRHMSIEDMESYYNCVRIIIKNKHLLKSDVAKTFANGSS"
misc_feature 185..1120
/locus_tag="HHNV_gp1"
/note="Viral methyltransferase; Region: Vmethyltransf;
pfam01660"
/db_xref="CDD:396298"
misc_feature <2114..2503
/locus_tag="HHNV_gp1"
/note="2OG-Fe(II) oxygenase superfamily; Region:
2OG-FeII_Oxy; cl21496"
/db_xref="CDD:451274"
misc_feature 2657..2980
/locus_tag="HHNV_gp1"
/note="OTU (ovarian tumor) domain of the
potexviruses/carlaviruses RNA replication protein family;
Region: OTU_RDRP-like; cd22792"
/db_xref="CDD:438613"
misc_feature order(2687..2689,2786..2788,2795..2797,2816..2827,
2906..2908,2945..2947,2954..2962)
/locus_tag="HHNV_gp1"
/note="putative polypeptide substrate binding site
[polypeptide binding]; other site"
/db_xref="CDD:438613"
misc_feature 2978..3241
/locus_tag="HHNV_gp1"
/note="Carlavirus endopeptidase; Region: Peptidase_C23;
pfam05379"
/db_xref="CDD:283122"
misc_feature <3341..>3544
/locus_tag="HHNV_gp1"
/note="thiol reductant ABC exporter, CydD subunit; Region:
CydD; TIGR02857"
/db_xref="CDD:274323"
misc_feature 3512..>3868
/locus_tag="HHNV_gp1"
/note="Viral (Superfamily 1) RNA helicase; Region:
Viral_helicase1; pfam01443"
/db_xref="CDD:366646"
misc_feature 4868..5821
/locus_tag="HHNV_gp1"
/note="catalytic core domain of RNA-dependent RNA
polymerase (RdRp) in the family Betaflexiviridae of
positive-sense single-stranded RNA [(+)ssRNA] viruses, in
the order Tymovirales; Region: Betaflexiviridae_RdRp;
cd23245"
/db_xref="CDD:438095"
misc_feature 5273..5317
/locus_tag="HHNV_gp1"
/note="conserved polymerase motif A; other site"
/db_xref="CDD:438095"
misc_feature 5441..5512
/locus_tag="HHNV_gp1"
/note="conserved polymerase motif B; other site"
/db_xref="CDD:438095"
misc_feature 5528..5572
/locus_tag="HHNV_gp1"
/note="conserved polymerase motif C; other site"
/db_xref="CDD:438095"
gene 5960..6664
/locus_tag="HHNV_gp2"
/db_xref="GeneID:7412076"
CDS 5960..6664
/locus_tag="HHNV_gp2"
/note="ORF II"
/codon_start=1
/product="triple gene block protein 1"
/protein_id="YP_002574615.1"
/db_xref="GeneID:7412076"
/translation="MDYLVNKLYKNKDFERTTLPLSSPIVINCVPGAGKSTFIKDLID
SDSRFVGLTFGAVPNPDLSSRGIISIKDYQPKSGDLVLIDEYTEGDHSNLNALALFGD
PLQSNSKHPKPPAHFVATFSHRFGEKTAKLLRDLDFHVHAEGADQVTLGNLYDLDPIG
QIVAVEPEVIALLCKHNCDFLDLKQARGKTFDRVTFYCAESNITPELRADYFVGLTRH
RKELLILNPYAALSTT"
misc_feature 6032..6637
/locus_tag="HHNV_gp2"
/note="Viral (Superfamily 1) RNA helicase; Region:
Viral_helicase1; pfam01443"
/db_xref="CDD:366646"
gene 6642..6968
/locus_tag="HHNV_gp3"
/db_xref="GeneID:7412077"
CDS 6642..6968
/locus_tag="HHNV_gp3"
/note="ORF III"
/codon_start=1
/product="triple gene block protein 2"
/protein_id="YP_002574616.1"
/db_xref="GeneID:7412077"
/translation="MPLSPPPDHSRSFLALAVGLTCAICLFALTRSTLPHVGDNLHSL
PHGGCYRDGTKQIYYGKPASRVPSSNLFGGFGFTTAVLIAVILAGLTIYKGRRTVVCH
SCRCSH"
misc_feature 6654..6959
/locus_tag="HHNV_gp3"
/note="Plant viral movement protein; Region:
Plant_vir_prot; pfam01307"
/db_xref="CDD:279627"
gene 6956..7159
/locus_tag="HHNV_gp4"
/db_xref="GeneID:7412078"
CDS 6956..7159
/locus_tag="HHNV_gp4"
/note="ORF IV"
/codon_start=1
/product="triple gene block protein 3"
/protein_id="YP_002574617.1"
/db_xref="GeneID:7412078"
/translation="MQSLSCFIIAAAGSCILGYLLLERLFAVNDPCTVHISGESVRII
GCAFTPDFIEYARTLKPFDHGFV"
misc_feature 6977..7147
/locus_tag="HHNV_gp4"
/note="7kD viral coat protein; Region: 7kD_coat;
pfam02495"
/db_xref="CDD:396861"
gene 7226..8155
/locus_tag="HHNV_gp5"
/db_xref="GeneID:7412079"
CDS 7226..8155
/locus_tag="HHNV_gp5"
/note="ORF V"
/codon_start=1
/product="capsid protein"
/protein_id="YP_002574618.1"
/db_xref="GeneID:7412079"
/translation="MPTEQEIEQQRRTAEAQQIERNRRSNTETQQQQRQATPPRRQQA
LDLEDEEQAVGLEKTLLDRFLKLKEFNLNNLTATRLVNSGFETGRPKARVAASMRGDM
ANIFTSPTLDTLQALPWNPVSSRLATAEELAKISAKIEALGFPRDQLAKLFWDVSRYC
ASNSSSPYSDPKGVIEFDGGAITRDAALAVIRDISSLRRVCRSYSKIVWNYMLVNAQP
PEDWQAKGFTENTKYAAFDFFDSIMNSAAIQPAEGLIRKPTPEEIIANETHKRLALDR
ASSNRRFANYSAEVTGGKFGRELKRSYRGSESD"
misc_feature 7412..7567
/locus_tag="HHNV_gp5"
/note="Carlavirus coat; Region: Flexi_CP_N; pfam08358"
/db_xref="CDD:149427"
misc_feature 7592..8011
/locus_tag="HHNV_gp5"
/note="Viral coat protein; Region: Flexi_CP; pfam00286"
/db_xref="CDD:425583"
gene 8155..8481
/locus_tag="HHNV_gp6"
/db_xref="GeneID:7412080"
CDS 8155..8481
/locus_tag="HHNV_gp6"
/note="ORF VI"
/codon_start=1
/product="putative nucleic acid binding protein"
/protein_id="YP_002574619.1"
/db_xref="GeneID:7412080"
/translation="MRIRDQKRALCSVFSFYCGNNRNDADVVGLIMSFVLSNAVGFGT
SNYAKKRRARQVNRCWRCYRVIGGLCLPKNCNGVTCTPTSSNIASFILTGHRVLDTRS
RRSRCH"
misc_feature 8200..8427
/locus_tag="HHNV_gp6"
/note="Carlavirus putative nucleic acid binding protein;
Region: Carla_C4; pfam01623"
/db_xref="CDD:250753"
3'UTR 8482..8542
ORIGIN
1 ggataaacac aactcggcat aattcggctt aattcaaaac aatcaagtca attacgtaat
61 ggcactcaca tacaggagtc ccatcgagaa tgtgctaaca acatttacaa caactgagca
121 gagctccatc tctgctccag cagttaaatg gtacaaagat cacgaggccg agcactttgc
181 cttattcaat tacgcgctcc ctgagtcagc taaacagcga ctatggcaaa gcggtctgta
241 tctaagtcca ttttccgcgc taccccacag ccacccagtg tgtaaaacct tagaaaatta
301 tatgctgtac actgtacttc ccacttatgt agataatacc ttttatttcg tagggataaa
361 gaatcacaaa ttagaatttc tgaagcaaag acgaaaacac gtcaatctcg tcgaaagcct
421 aaatcggtat gtaacgagtg ctgataaatt caggtatcca aatgactttg tcattgctag
481 gagtgaagaa atttgcggcc tcaagaggca tcagagattc ttatcaaatc cttcactcaa
541 aacgctgctg ccggatgtcg ttgcaaaatc gcaaaagaat cttttctttc acgatgaaat
601 acactactgg gattatgaca gtttaacgac cttcttggaa atcgtcaaac cgaacaagct
661 tgtatgcaca atggtctacc cccctgaact cttagttggt gctaaagaga gcctgaatcc
721 ttggtgctac cattttgagg tgcaaggtga ttctttccgg ttttatcctg atggagtgag
781 aacggaagga tatacccaac ctcttgcggg tggcaatcta ctgaaagcaa actccattgt
841 cttggctgat ggcacaacat atggggtgga tcttctatgc agcaagtttg cgcaccattt
901 gattggtctt tccaagggtg agtcaaaatt tcctgtggac cgcgcctttg gagattttga
961 tgctgtcagc gccgagggat taaagaagat ctgcgcgagg gtgcaaggtg ccatacctat
1021 atcttacgga acaatttcaa ggatttatag gtatttgcgc acgctaaaca agcctgatac
1081 ccaatctgcg atggctaaac taagtcagct actccctgaa ccaagtgggt atgagatcaa
1141 atttgtgcag gacttcagca agctggtcat caacactcct gtgacgcaaa caatgttcac
1201 gaacaattac tgtgaggcaa tgttacaaag tcttattgca agtgctccgc caattcttgg
1261 aaagtacttc agtaaatttg ccgctcttac ccttgataaa ttcattgagg agttaaaacc
1321 tttaaccttc aatttgaaac tcagggagta taaaagcaca agtaattgca acatcgatta
1381 tttcgacttt gcggctgatc tggagccaca gacggttttg cagctgctag atgacggctt
1441 tcaaagctct agaatgtttt atggtgagcg cacacgagcg ctttattact gcaatgagcc
1501 aagtttttca tgtttcgatt ttgatgattc tgttttagag cggaccctta ccgcttattt
1561 tgttaacgca catggaagtg agtcccaagt aagatttagt ctcgggcgtt taaagcactt
1621 ttcgtgtgca ttcttgcgga agtgctcact aactgcccaa gcatgctggg gtgtgacaac
1681 tgaaatgctg cttaggatta ggaaaagggt cgaagcgatc cttgttagat tttacaattt
1741 tagcttcttt ttagaacctt ccgtctggtt tgcggaaaca aaacggaggc gcagtgtgcg
1801 ctatataaac gcaacggatg aaatccccac aggtctattc tgccgtaatg atctgcacaa
1861 aagtgtcatc ggggaactta ttttgaaacg ccaagcgaga acccctgctg aaatccccat
1921 tgcgcccgtt aatgaaaacc acactgaggc tcttactatg ctggaattag agcctgattc
1981 tgatagcgat gatggcgtgg ctttacctga aactatccaa agtttcactt gtaagtgtgg
2041 ttgcattttg ccctttttta acgtcattgg agctgatttg tgcattctac ctacgcctga
2101 taaactaaaa ggtcgcactg caggttggta ctcaaaagat ggaaggccat actcatacaa
2161 tggtggggct cacaaatctc ttggatggcc gatctggctt gatacattct tggaattaaa
2221 tgctcacggg tacggtccct ttgattcggt actagtgcag gagtattcga atgattctgg
2281 catcggctac cacgcagata acgaggagat ttttaagccg gagggtgcga tcctgactat
2341 gtctatccgc ggtagcgctt ccttcggttt gaaatgctcc gctggcgagt gcggttttga
2401 gcaccttgaa tgcacctctt tcgttatgcc cagcggtttg caacaaacgc acaaacatcg
2461 ggttttcgga actaaaggca atcggatatc ccttacattt cgcatgttga gggatagtgc
2521 atacctgagc tccgatggga gtgacaatgg tttgggatct gaccatgacg aagaagatca
2581 cgctgacttt actgagtctt ctgaaacttt cggggttaaa ctcgatctgc gaaagacaca
2641 cccattgaac gctttcaagc ccattgaagt gcccgctgac ggagattgtt tttggcatgc
2701 tgtaggctac cttataggct taaatggcag tgaagtgaag aaagctgtag ctgagagatc
2761 caaagtagaa ctaaaggcta atgcagagct cactgcgcaa atggggaata aggtttttgc
2821 tgaaaatgaa gcctttgctg cagcttgtgt gctcctcgat attagcataa cttttataat
2881 aagtgatgag gggcacagtg tcatcttcaa caaagaagga tccactctaa tgctctacat
2941 caaactccag aatactcact gcagtccact tttgcctagg aatgactgtg tgattgtcgc
3001 aggtgcatca gctttatcaa ggcctgtgaa ggacgtctac aaagtgctaa tgcggcgcga
3061 gcactctcta attttcaaac agctctgcgc tggggaaggt ctcagtttga tgcttcttgg
3121 gcagttcttc tccatcttcg atattcacgc atatattaat ttcgaaggtg aacacatgga
3181 ggtgaacgaa agtggcagtt taaaacgctg ctttacagtt gagcaggagc atatcgcaca
3241 caatgtcaaa atgggctgca gtgctatcgc acccacgatg actggtagca acaatgctgt
3301 aagcttgaaa agcctcaagg ttctgaaagc atgcgggact gagttggtgt acactgtcga
3361 ggaagagcga gcacgtcgat tagccgatag tttacacagt ggaaccacgg gagctgtctg
3421 ttcttcactc ttcaatggta cgccaaatct cttgcaaggg ttgaatcccg attgggaagc
3481 gaggaatgta gtggccatac taggtacatt tggctctggg aaaagcacct tattcaagga
3541 tttgttcaaa aggaatcccg gaaagctaat atgctttgtt tcaccaagaa gaagtctggc
3601 gcaggaaatc aaagagagcg tgtttggaaa gtgcacttca cccgatggta aattcaaaat
3661 tgtgagaaat aagaaaaact gtaacttcaa tgtctgcact tttgagacat ttctcaaatt
3721 ggccaaaggt ttgaaagcgg ggcacaccct agtcctggac gaaattcaat tgtacccacc
3781 tggctatttg gatcttgttg cttgtttggt tcccaggagt tgtcaccttt ttgtcgttgg
3841 ggatccctgt caaagtaatt atgacagtga aggtgaccgc agcattttct caggggccgc
3901 aagtgacata cacaaaatgc ttgctaacgc aaagtacaaa ttcgtgacta gaagtcggag
3961 gtttttcaac aaaacttttt ccgggaggct gccatgcgct atggatgata gcaaattggt
4021 cgtatctgag gaatatttca tggctcggag ttttgaagaa gtccgtagct ttagcaaggt
4081 ttttactgaa gtcttcctag tgcctggttt tgacgagaag aagatcatca aagcgcattt
4141 ccccaattgc gaaaatatct taacatttgg ggagtcaact ggtagaactt ttgaatacgg
4201 ctccattctg atcacgcaaa gtggctttag cgtgtgcgag caaagatgga taactgcact
4261 ctccagattc tctagaaatt tactcttctt aaatttgacc gaggcgagct tcgaggccat
4321 tgctgagaac atggatgatc gtgcacttgg gaaatttttc acacagagtg cttcaatcga
4381 tgacttacgg aaaatattgc ccggggaacc acattttgcg gattactatg taccaaagct
4441 tggcaaagac cactgcgtta gagaggataa gcttgctggt gatccttggt tgaaaacaat
4501 ggtgttcctt ggccaagaag aggatgttga aaagtcagag attgaagaag cgatattggc
4561 tgaaccatgg ttcaaaactc acctccccct ctgtgagatg gaaagtgtgc gagcttcttg
4621 ggtccaaaat ttcaaagcaa aagaaaacag agaagtgcgc aaaggctatc tcgtgagcga
4681 tcaatttaca gatgagcact caaaaaatag gggaaaaata ctcacaaatg ccgctgagcg
4741 ctttgaagcc atttacccaa ggcacaaaaa cagcgatact gttacttttc ttatggccgt
4801 gaagaagcgc ttaagatttt ctaaacctat ggttgagtgc gctaagctaa atgaggctag
4861 aggctacgga aagtatctac ttgacaattt cttgaaattt gtgccgttga aagcccagca
4921 caatcctgaa ttcatggcca ggagtgtgag agatttcgaa gaaaagaaga caagtaagag
4981 tgcagcaaca atagaaaacc attctggacg ctcttgtagg gattggctag cagatgtggg
5041 gcttatattt atgaagtccc agatttgcac caaattcgac aacagattcc gtgtggccaa
5101 agctgcgcaa tcgatagttt gcttccagca ttcagtactg tgtcgattcg ccccatatat
5161 gaggtacatc gagatgaaac tacaggaagc cctgccgaag aacttctata ttcatagcgg
5221 caagggcttg gaagagttga acaaatgggt gcttggtggt aatttccggg gtatttgcac
5281 cgaatctgac tatgaagctt ttgatgcaag ccaagaccag cacatagtgg cttttgagct
5341 ggcttgcatg gaatacctcg gactaccaaa agacctcatt gccgactatt gctacatcaa
5401 aacgcacctg ggttccaaat tggggtcttt cgcaattatg cgcttctctg gggaggctag
5461 cacttttctt ttcaatacca tggcaaacat gttattcact ttcctgcggt acgagttgac
5521 tgggaaagag ttcattagtt tcgctgggga tgacatgtgc gcctctaaga ggttgagggt
5581 aagcgttgag catgagagct ttctagggaa actaaaattg aaagcaaaag tcaacttcac
5641 taccaaccca actttttgcg ggtggtgtct tacaaccgat gggatcttta aaaaacccca
5701 actagttttc gagaggctgt gcatagctaa agaaaccaat aacctggcta attgcattga
5761 taattacgca attgagattt cctatgctta caaacttggg gaagccgcag ttaggcacat
5821 gagcattgag gatatggaaa gttattacaa ctgtgtgcga ataattatca agaacaaaca
5881 cctgctcaag tcggacgttg caaagacctt tgcaaatggg agttcttagg tttagcttag
5941 gttttagcta taatattgaa tggattatct agtgaataaa ttgtataaga ataaagattt
6001 tgaacgcacc actttgccac tcagctctcc aattgttatt aattgtgtgc ctggtgcagg
6061 caagagtacg ttcattaagg acttaatcga ttccgattct cgttttgtgg gtttaacctt
6121 cggtgccgta cccaaccctg atctgagctc tcgcggcatc atttccatta aagattacca
6181 acccaaatct ggagatctgg tattgatcga cgaatatacc gagggtgatc attccaactt
6241 gaacgcgttg gctttgtttg gagacccact tcagagcaat tctaagcacc ccaaaccacc
6301 tgcgcacttc gttgctactt tctcacatcg ttttggggaa aaaactgcta aattactccg
6361 cgacctagat ttccacgttc acgctgaggg tgctgatcaa gttacccttg gtaatcttta
6421 cgatttggac ccaattgggc agattgtggc tgtcgaacct gaggtgatcg ctctactttg
6481 caagcataat tgcgatttct tggatctcaa acaggccagg ggtaaaactt ttgatcgggt
6541 gaccttctac tgcgctgaga gtaatataac tcccgagctg cgcgcggatt actttgttgg
6601 tttaaccagg cacaggaagg agttgttgat cttaaatcca tatgccgctc tctccaccac
6661 ctgatcactc taggagtttt cttgcactgg ccgttggtct tacttgtgct atttgcttgt
6721 tcgctctaac tagatctaca ttgccacacg tgggtgataa tttgcattcg ttaccacacg
6781 ggggttgtta tcgtgacggc actaaacaga tatactacgg aaaacctgcc agtcgggtac
6841 cttctagtaa cctcttcggt ggctttggct tcactaccgc ggttctaatt gctgtcatac
6901 tcgctggtct gaccatctac aaagggcgac gcacggttgt ttgtcactcc tgcagatgca
6961 gtcattaagt tgcttcatca ttgctgccgc aggttcatgc atacttggct atctactact
7021 agaacgactg tttgccgtta acgacccttg caccgtgcat attagcggag agtccgttag
7081 gattattggc tgtgctttca cacctgattt tatagaatac gcgagaacac tcaagccgtt
7141 tgaccacggg tttgtttaac cttaggtttg cggttgcgtc tttcgaatta cagtgatagg
7201 gaataataag acaaggtcaa gacgaatgcc gactgaacag gaaatcgaac aacagcggcg
7261 aactgctgag gcgcaacaaa ttgaacgcaa ccggaggagt aatacggaaa cgcagcaaca
7321 acaaaggcag gccacacccc cgagaaggca gcaggcactt gatttggagg atgaagaaca
7381 ggctgttggg ctcgaaaaga cactactcga tagatttctt aagcttaaag agttcaactt
7441 aaataatcta actgcaacgc gccttgtaaa ctctggcttc gagactggac gtcccaaagc
7501 gcgtgtagcc gcttccatgc gaggggacat ggcgaacatt ttcaccagtc ctacacttga
7561 cacgctgcag gccctgcctt ggaatcctgt ctcatctcgt ttggctaccg ccgaagaact
7621 ggccaaaatt tcagctaaga ttgaagcgct gggcttcccc agggatcaat tggccaaact
7681 cttctgggat gtgagtcgat actgcgctag caatagttcc tcaccttata gcgacccaaa
7741 aggagtcatc gaatttgacg gaggagcaat cactcgtgat gctgcattgg cagtcatccg
7801 agatattagc tctttgcgta gggtatgtcg cagttactcc aaaatcgttt ggaactacat
7861 gctggttaac gcgcagcctc cggaggattg gcaagctaag ggtttcaccg agaacaccaa
7921 atacgcagcc tttgacttct tcgatagcat catgaactcg gcagctatac agccagcaga
7981 ggggcttatt cgtaaaccaa cgcctgaaga aattattgct aacgagactc acaaacgctt
8041 ggcgcttgac agggcttctt cgaatcggag atttgctaat tattctgctg aagtcactgg
8101 ggggaaattc ggacgagaat tgaagaggag ttaccgcggt tctgagagcg actaatgagg
8161 atcagagatc agaaacgtgc tttgtgtagt gtgttttcct tctattgtgg aaataaccgc
8221 aatgatgcgg acgttgttgg tttgattatg tcgtttgtgt tatccaacgc tgttggcttt
8281 ggaacgtcga actacgcgaa aaaacgtaga gcacgtcaag tcaacagatg ttggcgttgt
8341 tatcgcgtca tcggtggact ctgtctacct aaaaattgta atggtgtcac ttgtacccct
8401 acatcatcaa atattgcaag ctttatcctg accgggcata gagtactcga cacccgctcc
8461 aggaggagtc gttgccacta aaacttaatt aatgatatgt cgtggaacgt ttaaaataaa
8521 tttgctttta atatattttt gc
//
