LOCUS NC_023425 6654 bp RNA linear VRL 01-FEB-2022
DEFINITION Avian hepatitis E virus, complete genome.
ACCESSION NC_023425
VERSION NC_023425.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Avian hepatitis E virus
ORGANISM Avian hepatitis E virus
Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
Hepelivirales; Hepeviridae; Orthohepevirinae; Avihepevirus;
Avihepevirus magniiecur.
REFERENCE 1 (bases 1 to 6654)
AUTHORS Huang,F.F., Sun,Z.F., Emerson,S.U., Purcell,R.H., Shivaprasad,H.L.,
Pierson,F.W., Toth,T.E. and Meng,X.J.
TITLE Determination and analysis of the complete genomic sequence of
avian hepatitis E virus (avian HEV) and attempts to infect rhesus
monkeys with avian HEV
JOURNAL J. Gen. Virol. 85 (PT 6), 1609-1618 (2004)
PUBMED 15166445
REFERENCE 2 (bases 1 to 6654)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2014) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 6654)
AUTHORS Huang,F.F., Sun,Z.F., Emerson,S.U., Purcell,R.H., Shivaprasad,H.L.,
Pierson,W.F., Toth,T.E. and Meng,X.J.
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2004) Department of Biomedical Sciences and
Pathobiology, College of Veterinary Medicine, Virginia Polytechnic
Institute and State University, 1410 Price's Fork Road, Blacksburg,
VA 24060, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to AY535004.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..6654
/organism="Avian hepatitis E virus"
/mol_type="genomic RNA"
/db_xref="taxon:2907992"
/country="USA"
gene 25..4620
/locus_tag="BA77_gp1"
/db_xref="GeneID:18263429"
CDS 25..4620
/locus_tag="BA77_gp1"
/note="includes functional domains like methyltransferase,
helicase and RdRp"
/codon_start=1
/product="non-structural polyprotein"
/protein_id="YP_009001465.1"
/db_xref="GeneID:18263429"
/translation="MDVSQFAESKGVKTALEAAALAAANTALRNARVVTPYLTQQQTK
NLLELFRGAQLRFEPRDNWAHPVQRVVHDALEQYVRRAAGPNCLEVGAHPRSINRHQA
SHRCFLPPVGRDEQRWQVAPRRGLCNLIRRALLNGVKVAREFCQLGFGACSHQCEVGI
ALYSLHDMRPADVACAMARHNMRTMYVVLHLPEEAMLPPGSYSNKFYNTVNTADKCII
TYADDSCAGYVHKREVLQDWITTTGVSGRHPMLIERVRAIGCHFVLLCTATQPCPMPY
TPYPSSNTVYVRNVYGPALGAGLFTPKCCVDATFYPVPRRVWQRLMMFGTTLDDDAFC
CSRLLTYLRGISTKVTVGNIVANEGWQPEEQQLTAVAIAAYLTVCHQRWVRTQGIARG
VRRLQAEHAQQFWFKVWELFTNTGTVPGYSAGFYRQLATWISGGLTIDFERRVFDKRV
KCGCCCVCERRPADPGCLCIDDFPDGANGLVKLKKWPIRAGTKSAVSKWAQVRVRADS
TEDLIDLSVPKLLTLKELAAAAIRKQPSAPPSLHILDRRPVGDPRRPVNCAPPAVSAG
PVPAPPGNPVIESVQGSGAGGPEVSESQPGLTPTREVTNMPLPPQRGQEEVLAVLPSG
ARVIVGNLLDVAADWLVNPANRDHQPGGGLCGMFHRRWPHLWPVCGEVQDLPTGPVIF
QQGPPKVIHAPGPDYRIKPDPDGLRRVYAVVHQAHGTVASPLISAGIYRAPARESFEA
WAATARDGDLLVVQRSMAQHIRDFVLNEGRHRPRELHVDRAMADMVNYGLATEPEPYN
ELVKGVEVAPMTVKYALIAGVPGSGKSSSVDHRGAVVITPTKTLAREWSARGATAVTP
HVAASAAPEGRVIVDEAYAIPPHLLVASLRRARDVVMLGDPHQIPALDFDGRCLTSAV
DLGLQPTSWRTVSHRCPWDVCIFLRTDYPTITTTSRVLRSVVFTGETIGQKIVFTQVA
KQSNPGSITVHEAQGSTFDQTTIIATLDARGLIASSRAHAIVALTRHRERCSVIDVGG
VLVEIGVTDAMFNNIEMQLVRPDAAAPAGVLRAPDDTVDGLLDIPPAHTDVAAVLTAE
AIGHAPLELAAINPPGPVLEQGLLYMPARLDGRDEVVKLQLSDTVHCRLAAPTSRLAV
INTLVGRYGKATKLPEVEYDLMDTIAQFWHHIGPINPSTLEYAEMCEAMLSKGQDGSL
IVHLDLQDADCSRITFFQKDCAKFTLDDPVAHGKVGQGISAWPKTLCALFGPWFRAIE
KHLVAGLPPGYYYGDLYTEADLHRSVLCAPAGHLVFENDFSEFDSTQNNVSLDLECEL
MRRFGMPDWMVALYHLVRSYWLLVAPKEALRGCWKKHSGEPGTLLWNTVWNMTVLHHV
YEFDRPSVLCFKGDDSVVVCESVRARPEGVSLVADCGLKMKDKTGPCGAFSNLLIFPG
AGVVCDLLRQWGRLTDKNWGPDIQRMQDLEQACKDFVARVVTQGKEMLTIQLVAGYYG
VEVGMVEVVWGALKACAAARETLVTNRLPVLNLSKED"
misc_feature 1936..2271
/locus_tag="BA77_gp1"
/note="X-domain (or Mac1 domain) of viral non-structural
protein 3 and related macrodomains; Region:
Macro_X_Nsp3-like; cd21557"
/db_xref="CDD:438957"
misc_feature order(1951..1959,1969..1989,2191..2196,2200..2214)
/locus_tag="BA77_gp1"
/note="ADP-ribose binding site [chemical binding]; other
site"
/db_xref="CDD:438957"
misc_feature 2467..3105
/locus_tag="BA77_gp1"
/note="Viral (Superfamily 1) RNA helicase; Region:
Viral_helicase1; pfam01443"
/db_xref="CDD:366646"
misc_feature 3481..4302
/locus_tag="BA77_gp1"
/note="catalytic core domain of RNA-dependent RNA
polymerase (RdRp) in the family Hepeviridae of
positive-sense single-stranded RNA [(+)ssRNA] viruses;
Region: Hepeviridae_RdRp; cd23259"
/db_xref="CDD:438109"
misc_feature 3910..3954
/locus_tag="BA77_gp1"
/note="conserved polymerase motif A; other site"
/db_xref="CDD:438109"
misc_feature 4090..4161
/locus_tag="BA77_gp1"
/note="conserved polymerase motif B; other site"
/db_xref="CDD:438109"
misc_feature 4177..4221
/locus_tag="BA77_gp1"
/note="conserved polymerase motif C; other site"
/db_xref="CDD:438109"
gene 4654..4917
/locus_tag="BA77_gp2"
/db_xref="GeneID:18263427"
CDS 4654..4917
/locus_tag="BA77_gp2"
/note="unknown function"
/codon_start=1
/product="cytoskeleton related protein"
/protein_id="YP_009001466.1"
/db_xref="GeneID:18263427"
/translation="MCLSCQFWCLECQESGVGCRCVDCCSCLQCAAGCQGAPKRSQPE
AGVASAAVTIQPSGALNNAPREPSAPPLSQTLSPRQVLARYQM"
gene 4707..6527
/locus_tag="BA77_gp3"
/db_xref="GeneID:18263428"
CDS 4707..6527
/locus_tag="BA77_gp3"
/note="structural protein"
/codon_start=1
/product="capsid protein"
/protein_id="YP_009001467.1"
/db_xref="GeneID:18263428"
/translation="MSLCRLLLMLAMCCGVSRGSQTLPAGGRRGQRRRDNSAQWSTQQ
RPEGAVGPAPLTDVVTAAGTRTVPDVDQAGAVLVRQYNLVTSPLGLATLGSTNALLYA
APVSPLMPLQDGTTSNIMSTESSNYAQYRVQGLTVRWRPVVPNAVGGFSISMAYWPQT
TSTPTSIDMNSITSTDVRVVLQPGSAGLLTIPHERLAYKNNGWRSVETVSVPQEDATS
GMLMVCVHGTPWNSYTNSVYTGPLGMVDFAIKLQLRNLSPGNTNARVTRVKVTAPHTI
KADPSGATITTAAAARFMADVRWGLGTAEDGEIGHGILGVLFNLADTVLGGLPSTLLR
AASGQYMYGRPVGNANGEPEVKLYMSVEDAVNDKPIMVPHDIDLGTSTVTCQDYGNQH
VDDRPSPAPAPKRALGTLRSGDVLRITGSMQYVTNAELLPQSVSQGYFGAGSTMMVHN
LITGVRAPASSVDWTKATVDGVQVKTVDASSGSNRFAALPAFGKPAVWGPQGAGYFYQ
YNSTHQEWIYFLQNGSSVVWYAYTNMLGQKSDTSILFEVRPIQASDQPWFLAHHTGGD
DCTTCLPLGLRTCCRQAPEDQSPETRRLLDRLSRTFPSPP"
misc_feature 4974..5852
/locus_tag="BA77_gp3"
/note="Astrovirus capsid protein precursor; Region:
Astro_capsid_N; pfam03115"
/db_xref="CDD:367340"
ORIGIN
1 gcatgacccc atgccagggt aagaatggac gtctcgcagt ttgcagagtc caagggggtt
61 aagactgcac tagaagcggc cgctctagct gcagccaata ccgccctgcg aaatgcgcgg
121 gtggtaaccc cctatcttac ccaacagcag actaagaatc tgctggagct gttccgtggt
181 gctcagttgc ggtttgagcc acgcgacaac tgggcgcacc ctgtgcagcg ggtcgtgcat
241 gatgcccttg agcagtatgt acgccgcgca gcggggccca attgcctgga ggtcggcgct
301 catccacgct ccattaatag gcatcaagcc tcgcaccgct gcttcttacc cccagttggg
361 cgtgatgagc agcggtggca ggtagcacca cggaggggtc tttgcaacct aatccgtcgc
421 gcgctgctca atggtgtcaa ggtggcgcgt gagttttgtc agttagggtt cggtgcctgc
481 tctcaccagt gtgaggtggg catagctctt tacagcttac acgacatgcg tcctgcggac
541 gtggcgtgtg cgatggcccg tcataacatg cgcactatgt acgtcgtatt gcatctacct
601 gaggaggcaa tgttaccacc agggtcctac tcaaacaagt tctacaacac agtgaacaca
661 gcggataaat gcattataac gtatgctgac gattcttgcg cggggtatgt gcacaagcgt
721 gaggtattac aggactggat aacgacaaca ggcgtttctg gtcggcatcc catgctaatt
781 gagcgggtca gggccatagg ttgccatttt gtgctgttgt gcactgcaac ccagccctgc
841 cccatgccgt atacgcctta cccgtcctca aacaccgtgt acgttaggaa tgtttacggg
901 cccgcgctgg gtgccggtct ttttacaccc aaatgttgtg ttgatgccac gttctaccct
961 gtgcccaggc gtgtgtggca gcggctgatg atgtttggta ccacacttga tgatgacgcc
1021 ttctgttgct cgcgcctgct aacttattta cgtgggattt caaccaaggt gacagtaggt
1081 aacattgtgg ccaatgaggg ctggcaaccg gaggagcagc agcttacggc tgtcgctata
1141 gctgcatacc ttactgtctg tcatcaaagg tgggtgcgca cacagggcat agctcggggt
1201 gtgaggcgct tacaggctga acatgcacag cagttctggt ttaaagtctg ggagttgttc
1261 accaacaccg gcactgtgcc cgggtattcg gccgggtttt atcgccagct cgccacatgg
1321 attagtggcg gccttaccat tgactttgaa cggcgtgttt tcgacaagcg tgtgaagtgt
1381 gggtgctgtt gcgtctgcga gcgccgtcct gctgaccccg ggtgcttgtg cattgacgat
1441 ttccccgatg gtgcgaacgg gctagtgaag ttgaaaaagt ggccgatacg agctggtacg
1501 aagtctgcag ttagcaagtg ggctcaagtc agggtccggg ctgatagcac ggaggatttg
1561 attgatctga gcgtgcccaa actactcaca cttaaagaac tcgccgctgc agcaatacgc
1621 aagcaaccgt ccgccccgcc atcattgcac attttggacc gccgaccggt aggtgatccc
1681 aggcgccccg ttaactgcgc accaccggcc gtctccgctg gccctgtacc ggcacccccg
1741 ggtaatcctg ttattgagtc tgttcagggg tcgggggctg gcggacctga ggtcagtgag
1801 tcccagcctg gcttgactcc gacgcgcgag gttactaata tgcccttgcc gccacagcgt
1861 ggtcaagagg aggtcctcgc cgtgttgcca tcgggggcgc gcgtcatcgt gggtaaccta
1921 ttggacgttg ccgccgactg gcttgttaac ccggctaatc gagaccatca gcccggaggc
1981 gggttgtgtg gcatgttcca ccgtcgctgg ccgcacttgt ggcctgtttg cggcgaggtc
2041 caggatttgc ccacgggccc ggtgattttc caacaggggc cacctaaggt tattcacgcc
2101 cctggcccgg actaccgtat taagcctgac cccgacggcc tccgcagagt atacgctgtt
2161 gtgcaccagg cgcatggcac ggtagctagc ccgttaatta gcgccgggat ataccgggca
2221 ccggcccggg aatcatttga ggcctgggcg gccaccgccc gtgatggtga cctactggtt
2281 gtgcagcgtt caatggctca gcacatcagg gactttgtgt tgaatgaggg tcgtcataga
2341 cctagggagc ttcatgttga ccgggctatg gctgacatgg ttaattatgg gctggcaacc
2401 gagcccgagc cgtacaatga gcttgtgaag ggcgttgagg ttgcgcctat gactgtgaaa
2461 tacgcgctta tagctggtgt cccaggcagc ggcaagtcgt cgtctgttga ccatcgtggg
2521 gctgttgtta ttacacccac caagacgttg gcacgtgagt ggtccgcgcg tggggccacg
2581 gctgttacac cccacgttgc agcaagtgca gcccccgagg gcagggtgat tgtggacgag
2641 gcgtatgcta tcccgccgca cctgcttgtg gcgtcccttc gtcgggcgcg cgatgttgtt
2701 atgttggggg atccgcacca gataccagca ttggatttcg atggacgctg tttaacgagc
2761 gccgttgatc ttgggttgca gcctaccagc tggcgcaccg tatcccaccg ttgcccttgg
2821 gacgtttgta tatttttgcg tactgattat ccgactatca ccacaaccag tagggtgctg
2881 cggtctgttg tgtttaccgg tgaaaccatt ggtcagaaga tagtgtttac ccaggtggcc
2941 aagcagtcga accccgggtc cataacggtc catgaggcgc agggcagtac ttttgatcag
3001 actactataa tcgccacgtt agatgctcgt ggccttatag cttcatctcg cgcgcatgcc
3061 atagttgcgc taacccgcca ccgggagcgc tgtagtgtga ttgatgttgg tggggtgctg
3121 gtcgagattg gagttactga tgccatgttt aacaatatcg aaatgcagct tgtgcgacct
3181 gatgctgcag cccctgccgg ggtgctacga gccccagacg acaccgtgga tggcttgttg
3241 gacatacccc cggcccacac tgatgtagcg gcggtgttaa cagctgaggc gattgggcat
3301 gcgccccttg aattggccgc cataaatcca cccgggcctg tattggagca gggcctatta
3361 tacatgccgg ccaggcttga tgggcgtgat gaggttgtta agctccagct gtcggatact
3421 gtacactgcc gcctggctgc acccactagc cgtcttgcgg tgattaacac attggttggg
3481 cggtacggta aagccactaa gctgcctgag gttgaatatg acttaatgga cactattgcg
3541 cagttctggc atcatatcgg accaatcaac ccctcaacac tggagtatgc agagatgtgc
3601 gaggccatgc ttagtaaggg ccaggatggg tccttgattg tacatctgga tttacaggat
3661 gctgattgtt ctcgcataac attcttccag aaggactgcg ctaaatttac gctggatgac
3721 cctgttgcac acggtaaagt gggacagggg atatctgcgt ggccgaaaac tttgtgtgca
3781 cttttcggcc cctggttccg ggctatagag aagcaccttg tggctgggtt acccccaggt
3841 tattactatg gggacctgta cacggaagcc gatctgcatc gttctgtgct ttgcgcgcct
3901 gctggtcacc ttgtttttga gaatgatttc tcagagtttg actcaacgca gaataatgtg
3961 tcccttgatc tcgaatgtga attgatgcgc aggtttggga tgcccgattg gatggtagcc
4021 ttgtaccatc ttgttcgatc atactggctc ttggttgccc cgaaagaagc ccttcgtggc
4081 tgttggaaaa aacactctgg tgagccgggc acccttttgt ggaatacagt ttggaacatg
4141 actgtgttgc atcatgttta tgagtttgat cgaccaagtg tgttgtgttt caaaggtgat
4201 gatagtgtcg ttgtctgtga atcggtgcgc gcccgtccag agggcgttag tctcgtggca
4261 gactgcgggc taaaaatgaa ggacaagacc ggcccgtgtg gcgccttttc caacctgctg
4321 atcttcccgg gagctggtgt tgtctgcgac ctgttacggc agtggggccg cttgactgac
4381 aagaactggg ggcccgacat tcagcggatg caggaccttg agcaagcgtg taaggatttt
4441 gttgcacgtg ttgtaactca gggtaaagag atgttgacca tccagcttgt ggcgggttat
4501 tatggtgtgg aagttggtat ggttgaggtg gtttgggggg ctttgaaggc ctgcgccgca
4561 gcccgcgaga ccctagtgac caacaggttg ccggtactaa acttatctaa ggaggactga
4621 acaaataaca atcattatgc agtctgcgcg tccatgtgcc ttagctgcca gttctggtgt
4681 ttggagtgcc aggaaagtgg ggtgggatgt cgctgtgtag attgttgctc atgcttgcaa
4741 tgtgctgcgg ggtgtcaagg ggctcccaaa cgctcccagc cggaggcagg cgtggccagc
4801 gccgccgtga caattcagcc cagtggagca ctcaacaacg ccccgaggga gccgtcggcc
4861 ccgcccctct cacagacgtt gtcaccgcgg caggtactcg cacggtacca gatgtagatc
4921 aagccggtgc cgtgctggtg cgccagtata atctagtgac cagcccgtta ggcctggcca
4981 cccttggtag caccaatgcc ttgctttatg ccgcaccggt gtcaccgtta atgccgcttc
5041 aggacggcac gacgtctaat atcatgagca cggagtctag caactatgct caataccgtg
5101 tacagggcct aactgtccgc tggcgcccag ttgtgccaaa tgcggtgggc ggcttctcta
5161 taagcatggc ctattggccc cagacaacat ccacccctac aagcattgac atgaattcca
5221 tcacgtccac tgacgtccgt gtggtgcttc agccgggctc tgctggtttg ctgactatac
5281 cacatgagcg tttggcgtat aagaacaatg gttggcggtc cgtcgaaacg gtatccgtcc
5341 cacaggagga tgccacgtcc ggcatgctca tggtttgtgt ccacgggacc ccctggaata
5401 gttataccaa tagtgtttac accgggccgc ttggtatggt tgattttgcc ataaagttac
5461 agctaaggaa cttgtcgccc ggtaatacaa atgccagggt cacccgtgtg aaggtgacgg
5521 ccccacatac catcaaggct gacccatctg gtgctaccat aacaacagca gctgcggcca
5581 ggtttatggc ggatgtgcgt tggggcttgg gcactgctga ggatggcgaa attggtcacg
5641 gcatccttgg tgttctgttt aacctggcgg acacagtttt aggtggcttg ccctcgacac
5701 tgctgcgggc ggcgagtggt cagtacatgt acggccggcc tgtggggaac gcgaacggcg
5761 agcctgaggt gaaactgtat atgtcggttg aggatgccgt taacgataaa cctattatgg
5821 tcccccatga catcgacctc gggaccagca ctgtcacctg ccaggactat gggaatcagc
5881 atgtggatga ccgcccatcc ccggccccgg cccctaagcg agctttgggc accctaaggt
5941 caggggatgt gttgcgtatt actggctcca tgcagtatgt gactaacgcc gagttgttac
6001 cgcagagtgt gtcacagggg tactttgggg ccggcagcac catgatggtg cataatttga
6061 tcactggtgt gcgcgccccc gccagttcag tcgactggac gaaggcaaca gtggatgggg
6121 tccaggtgaa gactgtcgat gctagttctg ggagtaatag gtttgcagcg ttacctgcat
6181 ttggaaagcc agctgtgtgg gggccccagg gcgctgggta tttctaccag tataacagca
6241 cccaccagga gtggatttat tttcttcaga atggtagctc cgtggtttgg tatgcatata
6301 ctaatatgtt gggccagaag tcagatacat ccattctttt tgaggtccgg ccaatccaag
6361 ctagtgatca gccttggttt ttggcacacc acactggcgg cgatgactgt accacctgtc
6421 tgcctctggg gttaagaaca tgttgccgcc aggcgccaga agaccagtca cctgagacgc
6481 gccggctcct agaccggctt agtaggacat tcccctcacc accctaatgt cgtggttttg
6541 gggttttagg ttgattttct gtatctgggc gtaattgccc ctatgtttaa tttattgtga
6601 tttttataac tgttcatttg attatttatg aaatcctccc atctcgggca tagt
//
