LOCUS NC_024768 9564 bp RNA linear VRL 13-AUG-2018
DEFINITION Chicken picornavirus 4 isolate 5C, complete genome.
ACCESSION NC_024768
VERSION NC_024768.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Chicken picornavirus 4
ORGANISM Chicken picornavirus 4
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Picornaviridae.
REFERENCE 1 (bases 1 to 9564)
AUTHORS Lau,S.K., Woo,P.C., Yip,C.C., Li,K.S., Fan,R.Y., Bai,R., Huang,Y.,
Chan,K.H. and Yuen,K.Y.
TITLE Chickens host diverse picornaviruses originated from potential
interspecies transmission with recombination
JOURNAL J. Gen. Virol. 95 (PT 9), 1929-1944 (2014)
PUBMED 24906980
REFERENCE 2 (bases 1 to 9564)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-SEP-2014) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 9564)
AUTHORS Lau,S.K.P., Woo,P.C.Y., Yip,C.C.Y., Li,K.S.M., Fan,R.Y.Y., Bai,R.,
Chan,K.H. and Yuen,K.Y.
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2013) Microbiology, The University of Hong Kong,
University Pathology Building, Queen Mary Hospital, Hong Kong,
China
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to KF979335.
##Assembly-Data-START##
Assembly Method :: BioEdit v. 7.1.3.0
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..9564
/organism="Chicken picornavirus 4"
/mol_type="genomic RNA"
/isolate="5C"
/host="Gallus gallus"
/db_xref="taxon:1534547"
/country="Hong Kong"
/collection_date="09-Sep-2008"
5'UTR 1..663
gene 664..8898
/locus_tag="KW71_gp1"
/db_xref="GeneID:20194306"
CDS 664..8898
/locus_tag="KW71_gp1"
/codon_start=1
/product="polyprotein"
/protein_id="YP_009054901.1"
/db_xref="GeneID:20194306"
/translation="MSSSQTHKPEDNAPLQSQQEDLAPSTAPHEKATVETTAAAVVQN
EQNVIFDNSWSDVRTIDAEIPRIVATYTWTSTQSSGDFLPVVTGSDAVETLPASPNPF
CLPNHLILSQPTSSIGLNVPAQIGLFQALFTRHALYRSGFKVEVTVNGTQFHGGSLFV
VAIPHPHVWMQSLSNTDAGTEKKWTALELVQVNQLGVFPSARLLPRNASAVTLDLPYV
GPAPQLETAALDVMYAIAILVETPLSIPTGTAPTLTVVMRVGAKDAHFFAPKPYQTPQ
SNLGGFDVPLDIPAPASLLQGLRVNTAQSAFVNTSPGSVAQIERRSRNTETSFLPART
EDWRSILSRPTLMTLVQFTAATTLGTNIFQTNVCPTGTCVTNRDTTQALPSASIKRLQ
GVPYLMQLARYFSQWRGSLTYTFEYTGPQVSSGRLLIAFLPGRIRAAKPGQGADYVET
GALLQNFTENLHVIWDLSNSTSVSITCPYAVATPWAPVVINSWQAPPLSGYSSGSLVA
VVMSPLVTPTVVAPTSTILVHLSAGPDFEMRFPAPIPVNTVPMYNGVVDQGPVVDDLP
QGEHYLTTMDSMSFQTFFNQSRFYGNFSAAPTSGTTTASSVTIPLSLISFAPSSGQLK
TAEVPVRMFAGLFTFLRADLRITVGIPFQNNLIVSYRPPTATPSTYAASGAGSPDSAA
SLLNGPSIILSTRASNMGVEFVVPFSAFASVFQTSWSQANRVDTRYNANTNQINPGDM
GTIFVASRLSSVNLTNVSVFIAFQNAEFFVPRPFPPLTSTSWDGTAPNNLERDFWEEE
DPTPVEFQSPKKTTLKIEQAKDQVARFEEYFDWLYSEIGDTISPEHALAICSAVESAI
NQCDDEVENQIAFAELPLEYPSSLPCPGVWFRGEFYRCCYLPCENRFFPQVAAHSPLP
VEHNLCELYEALRSFETMCLIDPLATSHCYSQLLHQLLESEWVIPEMKHEIRKKLVFL
LEMLSHPERIMAHWNWESCHTQAFRNLCQRMQRPLAPSAIDEDYFSGEEEAEFQAPTS
CDQKFLNLIQCYRSAMLVNPWHTFEVAYISFYDLTLREDVPQWFKDQVDDVCFENLCA
RAGDRIDVDNSVLLESYRQAFDELFSEEPDFFSDDEIEAEFQAPKPPVVAASAPKPRP
PTPLPSPVVSEDEDESEDEPDDIYVYYVDNGLYRHWGIRSKQQAISLKAHGFQCRVSY
TPEDLGNHVDYCAVGYNEWCKAVCRLGQIYDYSITHNCTDFVEEITSYQYSFQNTGYW
LAAGVVAAAVATTAIFHSVPPSWDERPFLPEKTTPRVVLVTPRRRVHKWRRATLERIV
ELKRKMLFQAPINIQLTNPAVDRAASITTTATLETLDEVKNMVPVLVNSASTVASSLS
AASASVEHLTKSMETFLENATAAIPGAVSAMESTAGELISSASKKIASIILKVIGFTL
VIFGNPSPSTIAGVIALLVAEVYDNAYLRKKMSDLAVSFTSKIKDLVGSLFGVSSCCD
EEPIFDDIDDAFHRYMLTRTETDFEFQAPSRLQEFNQGVLAMKNVEWIIEKVKELIDW
LIAKLKSKEKSSPEDYLKSRADYITDLYRDSLATASCQNVDVNLLNQRVKDTRDMLAY
CTNHRLAGAAHILSRTLANYEQTSRKLKTSTYASRPEPLVIYIHGSPGVGKSLLSNII
ASAYCKRKGVDFKTSVFAQPPGSEYFDGYTGQPVHVIDDFCQNTTGEDVKLFCQMVST
TPFVPPMAALEEKGVQYRSRLILATSNMATPQSNEIRIPGALERRCHIKVRAVLARAF
QTPAGRLDMAEAFKELGPAKSSDFKADCPYLNGAAMTLSVTRGEDRTREHMSVYDLCD
MIFDELDERDGNQTAFSNIIFQSPSQNVISFCKHVDHSPDSCYNIFIATSQGPIVHRF
DSAEDRNSWLQSQIPSLPKAGNVRCCPCKNPDCAKIQFTFKTDDEQIRSQVINFPGRE
VAEWWLRFVCGRPGSAYALESEIWPAPPIFIPTAQPIKNESIEKELKKLKKRSLISFT
ITGISAIASAIGLLIYFLRRRRDPEPQAPYSGAGGRQRQPPQQRPVPQRIVHYQAPYR
MPQIYPKVEKNCTSITFHQDSHSFDLTALFICGRTFVCNNHAFSHSHTIEIGGHKYKP
EELSPELLVRPSGVTDVVICTLPRGDERKNLVPYLLSQKDRPTNDDVLMVSRSKTIAA
NFECTNLRGRKSVCVKEFDNADEQNFHRCYTYDLKSTPGMCGAALISRNPARETLLGI
HFAGGPGVGIGVPLYKEDFAHLFQGNLKSIEHPGQPNHIPRRSALKKSPAYGAFPVKS
EPAILSQKDKRCEVDLDEVMFSKHVPDHEGWPTLEPAMAYVVEELMQKCGFSKDDPVP
MWTLEQAINGDGVMEGIDMGQSAGYPFSAQGRSRRSFFEWDGEKWQATEELKKLVDHA
LQHPDDYYYATFLKDELRPSEKVKAGKTRLVDSDSLPRILAMRMVFGPLFEAMLRKNG
SEIHSAVGCNPDVDWTRFYYEMGPDSFPYCFDLDYSCFDSSEPKVAFLLMAKYLEPYF
QHDVTPFLAAVATSKHVYGDKAYEMEGGMPSGCVGTSMFNCINNSAFIVSALIALKVS
PDSCKWICYGDDVIISTDEKALSRRIADFYSRNTNLKVTPACKSGDFPEESTFYEVSF
LKRFFVHDSHYPQLIHPYMPLEYLEQSSMWQTDGEYQQKLDSLAQLAFHAGGPDYRKF
CDTIQKKCRSRGTEVYFRPFEYYMAMWYAHFM"
mat_peptide 664..1839
/locus_tag="KW71_gp1"
/product="VP0"
/protein_id="YP_009055025.1"
misc_feature 1000..1476
/locus_tag="KW71_gp1"
/note="Picornavirus capsid protein domain_like.
Picornaviruses are non-enveloped plus-strand ssRNA animal
viruses with icosahedral capsids composed of 60 copies
each of 4 virus encoded proteins; alignment includes
picornaviridae, like poliovirus, hepatitis A...; Region:
rhv_like; cd00205"
/db_xref="CDD:119412"
misc_feature order(1009..1011,1087..1089,1093..1095,1099..1101,
1147..1149,1264..1266,1333..1335,1357..1359,1438..1440)
/locus_tag="KW71_gp1"
/note="drug-binding pocket [chemical binding]; other site"
/db_xref="CDD:119412"
misc_feature 1678..2298
/locus_tag="KW71_gp1"
/note="Picornavirus capsid protein domain_like.
Picornaviruses are non-enveloped plus-strand ssRNA animal
viruses with icosahedral capsids composed of 60 copies
each of 4 virus encoded proteins; alignment includes
picornaviridae, like poliovirus, hepatitis A...; Region:
rhv_like; cd00205"
/db_xref="CDD:119412"
misc_feature order(1768..1770,1894..1896,1900..1902,1906..1908,
1954..1956,2050..2052,2119..2121,2170..2172,2251..2253)
/locus_tag="KW71_gp1"
/note="drug-binding pocket [chemical binding]; other site"
/db_xref="CDD:119412"
mat_peptide 1840..2337
/locus_tag="KW71_gp1"
/product="VP3"
/protein_id="YP_009055026.1"
mat_peptide 2338..3081
/locus_tag="KW71_gp1"
/product="VP1"
/protein_id="YP_009055027.1"
misc_feature 2455..2988
/locus_tag="KW71_gp1"
/note="Picornavirus capsid protein domain_like.
Picornaviruses are non-enveloped plus-strand ssRNA animal
viruses with icosahedral capsids composed of 60 copies
each of 4 virus encoded proteins; alignment includes
picornaviridae, like poliovirus, hepatitis A...; Region:
rhv_like; cd00205"
/db_xref="CDD:119412"
misc_feature order(2515..2517,2593..2595,2599..2601,2605..2607,
2641..2643,2731..2733,2842..2844,2881..2883,2944..2946)
/locus_tag="KW71_gp1"
/note="drug-binding pocket [chemical binding]; other site"
/db_xref="CDD:119412"
mat_peptide 3082..4053
/locus_tag="KW71_gp1"
/product="hypothetical protein"
/protein_id="YP_009055028.1"
mat_peptide 4054..4650
/locus_tag="KW71_gp1"
/product="2A"
/protein_id="YP_009055029.1"
mat_peptide 4651..5226
/locus_tag="KW71_gp1"
/product="2B"
/protein_id="YP_009055030.1"
mat_peptide 5227..6342
/locus_tag="KW71_gp1"
/product="2C"
/protein_id="YP_009055031.1"
misc_feature 5614..5922
/locus_tag="KW71_gp1"
/note="RNA helicase; Region: RNA_helicase; pfam00910"
/db_xref="CDD:425942"
mat_peptide 6343..6792
/locus_tag="KW71_gp1"
/product="3A"
/protein_id="YP_009055032.1"
mat_peptide 6793..6873
/locus_tag="KW71_gp1"
/product="3B"
/protein_id="YP_009055033.1"
mat_peptide 6874..7479
/locus_tag="KW71_gp1"
/product="3C"
/protein_id="YP_009055034.1"
misc_feature 6973..7416
/locus_tag="KW71_gp1"
/note="3C cysteine protease (picornain 3C); Region:
Peptidase_C3; pfam00548"
/db_xref="CDD:278947"
mat_peptide 7480..8895
/locus_tag="KW71_gp1"
/product="3D"
/protein_id="YP_009055035.1"
misc_feature 7555..8844
/locus_tag="KW71_gp1"
/note="RNA-dependent RNA polymerase (RdRp) in the genus
Megrivirus of positive-sense single-stranded RNA
[(+)ssRNA] viruses, within the family Picornaviridae;
Region: Megrivirus_RdRp; cd23223"
/db_xref="CDD:438073"
misc_feature order(7795..7800,7807..7809,7816..7821,7855..7857,
7963..7965,7969..7971,8020..8022,8026..8028,8056..8058,
8089..8091,8122..8133,8368..8388,8476..8487,8626..8634,
8704..8706,8728..8730,8737..8742,8746..8754,8761..8763)
/locus_tag="KW71_gp1"
/note="putative RNA binding site [nucleotide binding];
other site"
/db_xref="CDD:438073"
misc_feature 7960..8025
/locus_tag="KW71_gp1"
/note="conserved polymerase motif F; other site"
/db_xref="CDD:438073"
misc_feature 8188..8232
/locus_tag="KW71_gp1"
/note="conserved polymerase motif A; other site"
/db_xref="CDD:438073"
misc_feature 8362..8433
/locus_tag="KW71_gp1"
/note="conserved polymerase motif B; other site"
/db_xref="CDD:438073"
misc_feature 8461..8505
/locus_tag="KW71_gp1"
/note="conserved polymerase motif C; other site"
/db_xref="CDD:438073"
3'UTR 8899..9564
ORIGIN
1 gggggctctc ccccacggcc tcttttcccg accggtctgg caaaccggac ggttatcctg
61 gttaggtgtc cgatggatgc tggaacgggg tggctatagc tgcctccttc tggcttcctt
121 tattgggcat tctagctggg ccctttgcca aaattccatc ttaatcttaa acccattttc
181 tatacccagg cttgcttgta actggtaagt tgacccactg gcttgtctta agactattct
241 ggtgttggtg gacactcctt ccacaagtaa gtattgtgga gttcatgctc gttctgaacc
301 gggaatggca caccccgtag taggatcttg cctctgccac atatacttgc gcctgttgct
361 tctagactat gggctactaa ggatgactac ggaccccttt ttgggtaatc tgtgtcaagt
421 ctactgtatc atctggtgta cgctggaaat ccttgttctg gaaactgcgt ctggaggtgg
481 tgctgaaata ttgcaagcca cagatgcatt tctggtcttg gtgccgctac taggtgttac
541 accccctgtg ggcaaatgta gaaccttggt ggacgcgtga gatgggaatc cacgcctggc
601 catagactgg ctgataagct cgcggctgat cgagttgcaa cagtaatcag ttgatttgcc
661 actatgtcgt cttctcaaac ccacaaacct gaagataatg ctcccctcca gtctcaacag
721 gaggatcttg ctccatctac agctccacat gagaaagcaa ctgtggagac aacagctgct
781 gctgttgttc agaatgaaca gaatgtcatc tttgacaatt cttggtcaga tgttaggaca
841 attgatgcag aaatacctag gattgttgct acctatactt ggacctcaac acaatcttct
901 ggtgactttc ttcccgttgt cacgggctct gatgctgtgg aaaccctccc tgcttcacca
961 aatccatttt gtctccctaa tcatctaatt ctgagtcagc ctacttcttc tattggtctt
1021 aatgtccctg cacaaatagg tctctttcaa gctctcttta cacgacatgc gctttatagg
1081 tcaggtttta aggttgaggt cacagtgaac ggtactcagt ttcacggtgg ttctcttttt
1141 gttgttgcaa tcccccaccc tcatgtttgg atgcaatcac tttctaatac agatgctgga
1201 actgagaaga aatggactgc acttgaactt gttcaggtca atcagcttgg tgtcttcccc
1261 tctgctagac ttcttccaag aaatgcctct gctgttacat tggatcttcc ttatgttggt
1321 cctgcacctc agcttgaaac tgcagccctt gatgtaatgt atgccattgc cattcttgta
1381 gagactcctc tttcaattcc tacaggaact gcccccacac taacagtggt gatgcgtgtg
1441 ggtgcgaaag atgctcattt ctttgctcca aaaccatatc agactccaca atcaaatctt
1501 ggaggttttg atgtgcccct ggatatcccc gccccagcct cactgctgca agggttacgt
1561 gttaacacag cacagtctgc tttcgttaac acatccccag ggtctgttgc gcaaattgaa
1621 agaaggtcaa gaaacacaga aactagcttc ctccctgccc ggactgaaga ttggagatct
1681 attctttcaa gacccaccct tatgactctg gtccaattta ctgctgctac aactcttgga
1741 accaatatct tccagacaaa tgtgtgtcca actggaactt gtgtcacaaa tcgtgacaca
1801 acacaagccc ttcctagtgc ttctatcaag cgacttcaag gtgtccccta ccttatgcag
1861 cttgcacgct atttttcaca atggcgtggt tccctaacct acacatttga gtacactgga
1921 cctcaggttt catctggcag actcctgatt gccttcctac caggtaggat tcgtgcggca
1981 aaaccaggac aaggtgctga ctatgtagaa actggagctc tccttcaaaa tttcacagaa
2041 aatcttcatg tcatctggga cctctctaat tctacttctg tttcaattac ctgcccctat
2101 gccgttgcta ctccctgggc tcctgttgta attaactcct ggcaagcgcc ccctctgtct
2161 ggttactcat caggatctct tgttgctgtt gtgatgtcac ctcttgtcac cccaactgtt
2221 gttgcaccca catctacgat cttggtgcat ctgtctgctg gtccagactt tgagatgcgc
2281 ttccctgcac caattcctgt gaacactgtt cccatgtaca atggggttgt ggatcaaggt
2341 cccgtcgtag atgatctccc tcagggagag cactacctca ctacaatgga ttccatgtct
2401 tttcaaacat tctttaatca gtctaggttc tatggaaatt tctcagctgc gccgacttca
2461 gggactacta ctgcaagttc ggtaaccatt ccactgtcac tgatctcatt tgctccctca
2521 tctggtcaac tgaagactgc agaagttcca gtgcgcatgt ttgctggtct tttcactttc
2581 ctgcgcgctg atctcaggat tactgtggga atccctttcc aaaacaatct gattgtttcc
2641 taccgtcctc ccactgcgac tccctcaact tatgctgctt caggagcagg ttccccggat
2701 tctgctgcat cccttctgaa tggtccttca attattcttt ctacccgcgc ttctaatatg
2761 ggtgttgagt ttgtggtccc cttctctgcc ttcgcttcag tatttcagac ctcctggtct
2821 caggcaaacc gggttgatac tcgctataat gcgaatacaa atcaaatcaa cccaggagat
2881 atgggaacta tctttgttgc atcccgcctt tcaagtgtga atctcacaaa tgtgtctgtc
2941 tttattgctt tccagaatgc tgaattcttt gttcctcgtc ccttcccccc tctcacatcc
3001 actagctggg atggcactgc tccaaacaat ctggagagag acttctggga ggaagaagat
3061 ccaactcctg tggagttcca gtctcccaag aagacaactc tgaaaattga acaagcaaaa
3121 gatcaagttg ccagatttga ggagtatttt gattggcttt attcagaaat tggagataca
3181 atttctccag aacatgctct tgctatctgt tctgctgttg agagtgcaat taatcagtgt
3241 gatgatgaag ttgaaaatca gattgccttt gctgaactcc cccttgagta cccgagttct
3301 ctcccttgtc ccggtgtttg gtttaggggt gaattttata ggtgctgtta tcttccttgc
3361 gagaacagat ttttccccca agtcgctgca cattcccctc tccctgttga gcacaatctt
3421 tgtgaactgt atgaagctct cagatctttt gaaactatgt gtttgattga tcctcttgca
3481 acttcccact gttattctca acttcttcac cagcttcttg aatcggagtg ggtgattcct
3541 gaaatgaagc atgagatcag gaagaagctg gtcttccttc ttgagatgct ctcccaccct
3601 gaaagaatta tggctcattg gaattgggaa tcctgccata ctcaggcttt caggaatctt
3661 tgccagagaa tgcagaggcc ccttgctcct agcgcaatcg atgaagacta cttctccggg
3721 gaagaggaag ctgaattcca agctcctaca tcttgtgatc aaaagtttct taatctgatt
3781 cagtgttaca gaagtgcaat gcttgtgaat ccctggcaca cctttgaagt tgcttacatc
3841 tccttttatg atctcactct ccgtgaagat gtacctcaat ggtttaaaga tcaggttgat
3901 gatgtgtgtt ttgagaatct gtgtgcaaga gccggcgatc gaatcgatgt ggataattct
3961 gtccttcttg aatcctacag acaagctttt gatgaactct tttccgaaga acccgatttc
4021 ttctctgatg atgaaattga agccgaattt caggccccta aaccccctgt tgttgctgct
4081 tctgctccaa agccccgtcc cccaaccccc cttccttctc ctgttgtttc tgaagatgaa
4141 gatgagagtg aggatgaacc tgacgatata tatgtctatt atgtagacaa tggactgtat
4201 cgtcattggg gaattcgtag caaacagcaa gcgatttccc tgaaggcaca cggctttcag
4261 tgccgtgttt cctatactcc tgaagatctt ggaaatcatg ttgattattg tgctgtgggt
4321 tataatgaat ggtgtaaggc tgtctgcaga ttaggtcaaa tttatgatta ttcaatcact
4381 cataattgca ctgactttgt tgaagaaatc acttcctatc agtattcttt ccaaaacact
4441 ggctattggc ttgctgctgg tgttgttgct gccgctgttg ctacaactgc aatctttcac
4501 tctgttcccc cctcctggga tgagaggcca tttctacccg agaaaacgac cccaagggtg
4561 gttctggtga ctcctcgccg gagggtacac aagtggagga gggcaactct tgaaaggatt
4621 gttgaactta agagaaagat gctctttcag gctccaatca atattcagct tacaaatccc
4681 gctgttgaca gagctgcctc aattaccact actgcaactc ttgaaacgct tgatgaggta
4741 aagaatatgg tgcctgtgct tgttaattct gcttctaccg tggcgtcttc tctctctgcc
4801 gcttccgctt ctgttgaaca tcttacaaaa tcaatggaaa cctttcttga gaatgcaact
4861 gctgcaatcc ccggtgctgt ttctgcaatg gaatctactg ctggtgaact tatttcctct
4921 gcttccaaga agattgcttc aattattctt aaagtgattg gttttaccct tgtgattttt
4981 ggaaatccct ccccttctac gattgctggt gtaattgctc tccttgttgc tgaagtgtat
5041 gataatgcct atcttagaaa gaagatgtct gatcttgctg tttcttttac atctaaaatt
5101 aaggatcttg taggttctct ctttggtgtg tctagttgtt gtgatgaaga acccatcttt
5161 gatgatattg atgatgcttt tcaccgctac atgcttaccc gcactgagac tgattttgag
5221 ttccaggccc cctctcgtct tcaagaattt aatcaaggtg tccttgcaat gaagaatgtt
5281 gagtggataa ttgagaaagt caaagaactt atcgattggc tgattgctaa gctcaagtcc
5341 aaggagaaat catctcccga ggactatctt aagtctagag ctgattacat tactgatctc
5401 tatcgcgatt ctcttgctac tgcctcctgt cagaatgttg atgtgaatct ccttaatcag
5461 cgtgtgaaag atactaggga tatgcttgcc tattgtacaa atcatagact tgctggtgct
5521 gctcatatcc tttctcgcac tctcgcaaat tatgaacaga cttctaggaa acttaagact
5581 tccacttatg cttctcgtcc agaacccctt gtgatttaca tccatggttc ccctggtgtt
5641 ggcaaatctc tcctttctaa tataattgcc tctgcttact gtaagagaaa gggagttgac
5701 tttaaaactt ctgtctttgc tcaacctcct ggctctgaat actttgatgg ctatactggt
5761 caacctgttc atgtgattga tgatttctgt caaaatacta ctggtgaaga tgtgaagctt
5821 ttctgtcaga tggtttctac cacccctttt gtccctccca tggctgctct tgaagaaaag
5881 ggtgttcagt atcgctctcg tctcattctt gcaacatcaa atatggcaac ccctcagtca
5941 aatgagattc ggattccagg tgctcttgag cgccgatgcc atattaaagt acgtgctgtt
6001 cttgcacgtg ctttccagac tcctgctggt cgtctggata tggctgaagc ctttaaagaa
6061 cttggacctg ctaagtcctc tgactttaaa gcagattgtc cgtatctcaa tggtgctgcc
6121 atgactctgt ctgttacaag aggcgaggat cgtactcgtg aacatatgtc tgtctatgat
6181 ctctgtgaca tgatttttga tgagcttgat gagcgtgatg gaaatcagac tgctttctct
6241 aatattatct tccaatcccc ctcccagaat gtgatctctt tctgtaagca tgttgatcat
6301 tcccctgact cttgctacaa tatttttatt gccacttccc aaggtccaat tgtacatagg
6361 tttgattctg ctgaagatag aaattcttgg ctccaatctc aaattccctc tctccctaaa
6421 gctggaaatg ttaggtgctg tccctgtaag aatcctgatt gtgcaaagat tcaattcact
6481 ttcaagactg atgatgaaca gattcgctcc caggttatta acttccctgg acgtgaggtt
6541 gccgaatggt ggcttcgttt cgtctgtggg agacctggaa gtgcctatgc actcgaaagt
6601 gagatctggc ctgctccccc tatcttcatt cctactgctc aaccaattaa gaatgaatca
6661 attgagaagg agctgaagaa gctcaagaaa aggtcactga tttcttttac aattactgga
6721 atttctgcaa ttgcttctgc tattggtctt ctgatctatt ttctgagacg aaggcgtgac
6781 cccgagcctc aggctccata ttctggagca ggaggccggc agcgccaacc gccgcaacag
6841 cggcctgtgc ctcagaggat tgtgcattat caggctccct atcgcatgcc tcagatctat
6901 cctaaagtag agaagaattg cacttcaatt acttttcatc aagattctca ttcttttgat
6961 cttactgctc tcttcatttg tggaagaact tttgtgtgta ataatcatgc cttctcccac
7021 tcccatacta ttgaaattgg aggtcataaa tataaacctg aagaactctc tccagaactt
7081 cttgttcgcc cctctggtgt gactgatgtt gtgatctgca cccttccccg tggtgatgaa
7141 agaaagaatc ttgttcccta tcttctctct cagaaggatc gtcccacgaa cgacgatgtt
7201 ctcatggtct ctagatcaaa gaccattgct gcaaattttg agtgtacaaa tctgagaggg
7261 aggaaatcag tgtgtgtgaa agaatttgac aatgctgatg aacagaactt tcaccgctgt
7321 tacacttatg atctcaaatc aacccctggt atgtgtggtg ctgcccttat ttcccgtaat
7381 cctgctcgtg aaaccctcct cggaattcac tttgctggtg gtcctggtgt tggaattggt
7441 gttcccctct ataaagaaga ttttgcccat cttttccaag gaaatctgaa atctattgaa
7501 catcctggtc aacccaatca cattccccgc cgatctgctc tgaaaaagtc tcctgcttat
7561 ggtgctttcc ccgtgaaatc tgaacctgct atcctttctc agaaagataa gagatgtgag
7621 gtagaccttg atgaagtcat gttcagtaaa catgtcccag accacgaagg ctggccgact
7681 ctcgaaccgg ctatggctta tgtggttgag gagctgatgc agaagtgtgg tttttccaag
7741 gatgatcctg ttccaatgtg gactcttgaa caggctatca atggtgatgg cgtgatggaa
7801 ggaattgaca tgggacagtc agctggatat cccttctctg ctcaggggcg ctcccgtcgg
7861 agtttctttg agtgggatgg tgagaaatgg caagctactg aagaacttaa gaagcttgtt
7921 gaccatgctc ttcaacatcc agatgactac tactatgcca cattccttaa ggatgaattg
7981 agaccttctg agaaggtgaa ggcagggaaa acccgtcttg ttgattctga ttcccttccc
8041 cgtattcttg caatgagaat ggtgtttggc cccctctttg aagctatgct cagaaagaat
8101 ggttctgaaa tccactctgc tgtaggatgt aaccctgatg ttgattggac taggttttac
8161 tatgagatgg gtcctgattc ctttccctat tgttttgatc ttgactattc ttgctttgat
8221 tcctctgaac caaaagttgc ctttcttttg atggctaaat atcttgaacc ttatttccag
8281 catgatgtta ctcccttcct tgctgcagtt gcgacatcca aacatgtcta tggagacaaa
8341 gcatatgaga tggaaggagg aatgccttct ggatgtgttg ggacaagtat gtttaactgc
8401 atcaataact ctgcttttat tgtttctgct ctgatcgcct tgaaagtttc tcctgattct
8461 tgtaagtgga tctgctatgg tgatgatgtg attatttcta cagatgagaa agctctctct
8521 cgcaggattg ctgattttta ttctaggaat accaatctga aagttactcc tgcttgcaag
8581 tctggtgact tccctgaaga atcaaccttc tatgaagttt ccttcctgaa acgcttcttt
8641 gtccatgatt cccactatcc tcagctgatc cacccctaca tgcctcttga atatctggaa
8701 caatcatcca tgtggcaaac tgatggtgaa tatcaacaga aactggactc tctggctcaa
8761 cttgctttcc atgctggcgg acctgactac agaaagtttt gtgacactat ccagaagaag
8821 tgccgctcga ggggcactga ggtttatttc aggccttttg agtactacat ggctatgtgg
8881 tacgcgcact tcatgtaaat tatgggtatt acagtttcta caatcaataa tattaatcag
8941 atttttgctg taggttctac tgttacttcc tttactcttc aatcagcttc tattattgta
9001 atgtcaatag gtgttttggt attagtgatt ttagctggtg ttgtaattta ttatttttgg
9061 aagaaacatc gtcgtgggca gagttctagg aggagagagg agaagattct ggcgcgacta
9121 attgaaaagg ggcttgtgtc ccccgatact cgtcttcctg atggtggaaa cgaggtaatt
9181 gaaagtataa agctctagct caggagttga aactgagtag ccgttggaat cggctatata
9241 aattatccaa ccctctagct caggaggatt taaactgagt acccgttgga atcgggtata
9301 taaattatct atttagttgt taagttttag tttgttaagt tttgctttaa ttaattttag
9361 tttagtcagt ttagtgtaaa agttaagttt agtaagcttt gccctcaacc cttaaggttg
9421 ttgtagcttg attaagcgaa cgaaatggga cgtatgatcc atcttggagt gggtcagacc
9481 ctggtccggg gcaataggac cactgtttcg cgtttaatcc tcaccgctta ggattagatt
9541 ttcatttgct tcactttgct tttt
//
