LOCUS NC_034242 10370 bp RNA linear VRL 24-MAY-2019
DEFINITION Ochlerotatus caspius flavivirus isolate 1608 polyprotein gene,
complete cds.
ACCESSION NC_034242
VERSION NC_034242.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Ochlerotatus caspius flavivirus
ORGANISM Ochlerotatus caspius flavivirus
Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Flasuviricetes;
Amarillovirales; Flaviviridae; Flavivirus.
REFERENCE 1 (bases 1 to 10370)
AUTHORS Ergunay,K., Litzba,N., Brinkmann,A., Gunay,F., Sarikaya,Y., Kar,S.,
Orsten,S., Oter,K., Domingo,C., Erisoz Kasap,O., Ozkul,A.,
Mitchell,L., Nitsche,A., Alten,B. and Linton,Y.M.
TITLE Co-circulation of West Nile virus and distinct insect-specific
flaviviruses in Turkey
JOURNAL Parasit Vectors 10 (1), 149 (2017)
PUBMED 28320443
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 10370)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (04-APR-2017) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 10370)
AUTHORS Ergunay,K. and Linton,Y.
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2016) Department of Medical Microbiology,
Virology Unit, Hacettepe University, Faculty of Medicine, Morpholoy
Building 3rd floor, Ankara 06100, Turkey
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to KY345399.
##Assembly-Data-START##
Assembly Method :: Geneious v. 9.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..10370
/organism="Ochlerotatus caspius flavivirus"
/mol_type="genomic RNA"
/isolate="1608"
/isolation_source="mosquito pool"
/host="Ochlerotatus caspius"
/db_xref="taxon:1244565"
/country="Turkey"
/collection_date="03-Aug-2015"
5'UTR 1..64
gene 65..10222
/gene="POLY"
/locus_tag="B6251_gp1"
/db_xref="GeneID:31652851"
CDS 65..10222
/gene="POLY"
/locus_tag="B6251_gp1"
/codon_start=1
/product="polyprotein"
/protein_id="YP_009352228.1"
/db_xref="GeneID:31652851"
/translation="MHRWRDLLPDKGKKNRSPAVRRQGGITKGVDRKIIPPSGSKERK
TGTERKVKKGVARMKPNWLSFGTGNQRSMWRQIFSVDLMEGLLLLIALMSNLYERVQR
DIADLKRRVTRLEKERSHPRKVPIMLLCGLIVVSGLSIELALDENGDVEMWADNQNIT
NYAHLIKVPADVCLAGMVITKHCPKVEKMTDLSDIDCGSTWVEFILTYTRCMVLGRET
RQKVDDKSPLTKFKEDLSTLETEAFQLLKRHAFSTILALLTLAIVLKWPIWVVVLLGF
LAWNVVKGEFVEPFLVLKHDHNTMLTTRLYPGEIAHIATPTGLLDIRVGNAGIFGGQL
FRELLRDCKVNASYSTDICPGGSQLNMEAIQGPGRVCFTAPYNRGWGTGCFKWGIGAV
ATCVELNCSSSMGVHLLTGSSVVANVSVGFHSTNDTKMLVPDAPTTLKFGKLGTVTMN
CRLGNDRIATSYYHVTDGLATGLFLKAQIDAWSGPFRMAGLTGGFDKIVKWGQVTPNE
VKVKRISEMELDWDKAITTHDGFVNTYFWCQIAVNKLVVGTFSSCKSEAQTVFSQSPW
GFEGIAEITLKEAQKSICSLPLSCVGCSLLSSKVVFLETTTKAAIHVGCGNGTSVLTV
GTTPVSIDCVVTPLSQVWRLVSHVTGRYTKLGFGGIGGVIHDILQACGWVFTWDSWKV
ILILGGLVALFIVFDRKTVLVVIIASAVVYVKADVGCGIDFDRKTYTCGRGLFIWKGI
GTYPASDHSVEFESYDFLAAYLKEQFKAERKVCIVCEDLVQCEAARKAASAVYRDLGH
PFVYVNVSSSYGRSFAEVPKRVHTVSVGVDVVEMAMMVSNNKPSGPFGDLPTSIVSWS
TAPENEDHLVLRVVTSSTPYRQVCGKAIGFQYDFVGFRRAVYGSNVQLKISKKVSIEC
PTYLAGIAVKNDRTVFTDGMFWMSSRKANDSYAIDELEMEQSHRCVWPNQYTPDMVQD
PRDNDLFVPPEWGGPRSKANHIPGYKMQISFPWDKAPIKLVDGSVPGTIVTQISKCEG
RGIPVMVDPAVNPNWCCKSCTRIFHFEVDGKLYYPMEIRPDVKEAKNKRSPVIEEPLG
DDTAETVTDWLSKTYRVPSANAEDFLNPKLILTKANAMVGEVVNLLCLALAMQVVTHT
WRHKSLARFHLCCLLFLLFGVPTVFGFVGIYTWMNILPISHGSARMCNLTIHLWAVLQ
HRSSGMFLWGQTLKLQFQTSLAGQMLLLTMQMLHQAIYAHSSMLGWGIEVFLSVIVMQ
NLYTVVDHIHPRLIAYCLLFGWRTGLCIGCGFLLMYLTKRWMTIVAASPSAGGWRSGY
RALCSSTLTLLFTAVGVVGVIASDYGGYPGASAAIAACLIAGIKMTDFLATRLSLEFV
STGQFPEGTTIEKEKETYDGTFRASFTVEGIKLLDHTEPVPLVFAISYVALGAVTCKI
HPGLGVIYAVAMVATNLPSLLQVYVLSICTNAFRSDELIGTAIASVEPELSKDFGNIP
DGIYRVNNHGIAFKSHRGVGIVKNGVFHTLMHITMNEPVTWQNKLVGPYMGNSLKDYL
CYGGNWQLPSFDPTDEVGIMVCKSDRSVEYKRHEVGKIDVDGVPHMYFTKDYGRGTSG
SPIFVNGEPVALYGFGFFLYNTYRSLVVPVPRADIEAGESAEGLVEENSSIVNKFFVD
WHPGKGKTRKVIVKHVLEAIRDSRRIVILAPTRVVMAEIMKALEESTHKAISKSMSHT
SHNGVTVACHATFTDFILAHGLSRFKAQEVIMDECHFLDPRSIAARGILEHLAQKRGV
KVVFMSATIPGREPSIGSNYEIAEQALQFPREVTSRWIGDVSEGKTVVFVPSHKVGDK
LALGSPQSISLHRNNFNTNYSIARSDDIKYVYTTDISEMGANFNATTVVDFRVAIKPK
ILNDCEVILAPTPITRSSMVQRRGRVGRQSPGRYIYPANKGTEEAANDLACWTEAQMI
LDQLDLTMMAEEAPYSNHPGAYKLVGKSFQVFKKLLEDKDDVPIWLSWKWADNAEHQY
AALFEGERLENVPRMVNTREYSSIEYKPKFIDARFERLSWEQRKLAIQFYMGTRSFLP
VGLFSKVLTQIIQAGVVNTAWKKIGDVGLVFMEGGDPHSKDESIVAWTILVGGMLCVI
ILMICVWALRIVMRMVFGSREKHSSVPTLLADSQPYLVCLVPVATHLAGVPVPVTIVV
FVILFLTFPLIYRSAGQRSYVDIDLVKWILVGGGFIIGVICWELRLLPNITSDLQSIA
HKRTRTDSSGFQQESDWGFSWFDFAQPVPTSVELTSVVITTFTMALFLNQIVGWSYEA
DWLKSYFDHKGVGHIMGGFRLDTISWGSALSSLLGTLSYASWGAIIIGMGGAMIYFFF
MVKMLKWNFTGGSTIGLENNAMRQDRETGLNRRPFHDSRRSLLYGVVIFECALWVFCF
MSVFDLVIASCVSTYCVWIIFNASSEHHRNVDLGSVCSFVGLLYATCPSQKCVQVLIR
FALSRLNITTRSLEKSATGGLGHRWKKILNAMSQDEFNAYRLYGVDETDKGDYVSRGG
LKLRELTLKYGWKPEGICVDLGCGRGGWSQHLAMDPRVTRIEAYTLGGTTRENPQPVK
TLGHNLIRFKTGVNVYNMAPTFANTIVCDIGESDPKTEVEASRTIRVLSTLGSWLEKN
PNAEFVCKVLCPYPVEVLRLLETFQHKYGGRIVRSTFSRNSSAEMYYISGGRNNIVKV
VFTTLHALIARLRTKPDKIVREPIRLPVGTRSDPGHKVKDMNPKMIATRVEKLRNEHK
DTWFIDSNHPYQSFRYVGSYVTDDINPGGQTVNPLMRKMMWPWEMVGGVVNFMMTDVS
TYAQQKVLREKVDTLSPEPPKNIKAINRLITEFQIRSYLKRGLRPRILTMEQYAENVK
SSAAIGSWSSDVPWNNVRAALSDANFHALVDEERRLHLAGDCRMCVYNTMGKKEKKPA
SMGVAKGSRTIWYMWLGSRFLEYEALGFLNEDHWVSRENLACGVGGVGVNYFGYYLQE
ISKKGKFFIADDIAGWDTRINESDLADEEHLIMSMISDTRHRALATAIFKFAYQNIVA
LFPRNHPGFGSGTVMDVVARTDQRGSGQVVTYALNTITNAKIQLGRMIEAEGLLGAPE
SVIVKWLNDNGEDRLSAMVVAGDDVVVATNNDKFSHSLDYLNLNGKIRKDIDPSLPSR
VQTNWETVEFCSHHYHLMTLRDGRRIIVPCRDQNEVIGRGRIQKGGLVTIADSACLAK
AYGQMWALYFFHRRDLRMAFMAITSSVPVDWFPEGRTSWSIHQNKEWMTTEDMLRVWN
TVWIHDNNWMEDKTEVTAWKDIPYLPKSIDIKCGSQIGSKDRATWSRELPSTVMAIRK
ILDHETRMENVYKDFLSGMGRFREDNDPMAAGVRF"
misc_feature 2216..3286
/gene="POLY"
/locus_tag="B6251_gp1"
/note="Flavivirus non-structural Protein NS1; Region:
Flavi_NS1; pfam00948"
/db_xref="CDD:279316"
misc_feature 4547..4936
/gene="POLY"
/locus_tag="B6251_gp1"
/note="Peptidase S7, Flavivirus NS3 serine protease;
Region: Peptidase_S7; cl29867"
/db_xref="CDD:453075"
misc_feature 5060..5476
/gene="POLY"
/locus_tag="B6251_gp1"
/note="N-terminal helicase domain of the DEAD-box helicase
superfamily; Region: DEAD-like_helicase_N; cl28899"
/db_xref="CDD:452890"
misc_feature order(5075..5095,5339..5341)
/gene="POLY"
/locus_tag="B6251_gp1"
/note="putative ATP binding site [chemical binding]; other
site"
/db_xref="CDD:350670"
misc_feature 5480..5872
/gene="POLY"
/locus_tag="B6251_gp1"
/note="C-terminal helicase domain of the DEAD-like
helicases; Region: DEAD-like_helicase_C; cl38915"
/db_xref="CDD:365791"
misc_feature 5837..5839
/gene="POLY"
/locus_tag="B6251_gp1"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:350171"
misc_feature 7565..8227
/gene="POLY"
/locus_tag="B6251_gp1"
/note="Cap-0 specific (nucleoside-2'-O-)-methyltransferase
of flaviviridae; Region: capping_2-OMTase_Flaviviridae;
cd20761"
/db_xref="CDD:394920"
misc_feature order(7580..7582,7589..7594,7598..7600,7949..7954,
8147..8149)
/gene="POLY"
/locus_tag="B6251_gp1"
/note="nucleic acid substrate binding site [nucleotide
binding]; other site"
/db_xref="CDD:394920"
misc_feature order(7742..7750,7757..7762,7811..7816,7889..7894,
7937..7942)
/gene="POLY"
/locus_tag="B6251_gp1"
/note="SAM binding site [chemical binding]; other site"
/db_xref="CDD:394920"
misc_feature order(7937..7939,8048..8050,8156..8158)
/gene="POLY"
/locus_tag="B6251_gp1"
/note="active site"
/db_xref="CDD:394920"
misc_feature 8465..10162
/gene="POLY"
/locus_tag="B6251_gp1"
/note="conserved catalytic core domain of RNA-dependent
RNA polymerase (RdRp) from the positive-sense
single-stranded RNA [(+)ssRNA] viruses and closely related
viruses; Region: ps-ssRNAv_RdRp-like; cl40470"
/db_xref="CDD:454764"
misc_feature 9089..9133
/gene="POLY"
/locus_tag="B6251_gp1"
/note="conserved polymerase motif A; other site"
/db_xref="CDD:438017"
misc_feature order(9314..9364,9368..9385)
/gene="POLY"
/locus_tag="B6251_gp1"
/note="conserved polymerase motif B; other site"
/db_xref="CDD:438017"
misc_feature order(9464..9475,9479..9508)
/gene="POLY"
/locus_tag="B6251_gp1"
/note="conserved polymerase motif C; other site"
/db_xref="CDD:438017"
3'UTR 10223..>10370
ORIGIN
1 gtctgattat aacggaatag ctgtttgaaa ggtgaaaatc ttttttcctg tcgtttgtat
61 caaaatgcac aggtggagag accttcttcc cgacaagggg aagaaaaatc gtagtcctgc
121 agtgaggcgg cagggcggga tcacgaaagg ggttgatcgg aagatcatcc ctccttcggg
181 atcaaaagaa agaaaaaccg gaacagagag gaaagtgaag aaaggtgtgg ctagaatgaa
241 gcccaattgg ctgtcatttg ggactggaaa tcaacgatca atgtggcgac aaattttttc
301 cgttgaccta atggaagggc tattgctatt gattgctctc atgtcgaacc tctatgagcg
361 agttcaacga gacattgcgg acctgaagag acgtgtgacg aggctggaga aagagcgttc
421 gcaccctaga aaggtgccaa taatgcttct ttgcgggctg attgtcgtat ctggactgtc
481 gattgaactg gcgcttgatg aaaatggtga cgtggaaatg tgggctgaca atcagaacat
541 tacgaactat gcccatttga taaaggtacc ggctgatgtc tgccttgcag gaatggttat
601 tacaaaacac tgtcccaagg ttgaaaagat gacggattta tctgacattg attgtggctc
661 tacatgggtg gaattcatac tgacgtacac gcggtgcatg gtcctgggaa gagagacccg
721 tcaaaaggtg gatgacaaat ccccactaac caagttcaag gaagatctgt ctactctcga
781 aacggaggcg ttccaacttc ttaagaggca cgcattttca actattctag cgttactcac
841 attggcgatc gtcttgaaat ggccaatttg ggttgtcgtc ttgttgggat tcttggcctg
901 gaacgtcgtt aaaggggagt ttgttgaacc ttttcttgtc ctcaagcatg accataatac
961 catgttaaca actcgtttgt accccggaga aattgcccat atcgccacgc caacgggctt
1021 gcttgacatc cgcgttggaa atgccgggat atttggaggc caactctttc gagaactact
1081 ccgcgattgc aaggtaaacg catcctattc aactgacatc tgcccaggtg gatctcagct
1141 gaacatggaa gctattcaag gaccaggaag ggtctgtttc acagcccctt acaatcgtgg
1201 atggggaaca ggttgtttca aatggggaat cggagctgtt gccacgtgcg ttgagctgaa
1261 ttgttctagt agtatgggcg tccatttgct tactggttca tctgtcgtag cgaatgtgtc
1321 agttggcttt cattcgacga atgacacaaa gatgctcgtt cctgacgcac ccacaacgct
1381 caagtttggt aagttgggaa ctgtgacgat gaactgccgg ctcggaaatg acagaattgc
1441 aactagttac taccatgtca ctgatggctt ggcaacaggc ttgttcttga aagcacaaat
1501 tgacgcctgg tcgggcccat ttcgtatggc aggactaact ggaggctttg acaagatcgt
1561 taagtggggg caagtgactc caaatgaagt caaggtgaag cggatctctg agatggaact
1621 ggactgggac aaggcaataa caacacatga tggtttcgta aacacgtact tttggtgcca
1681 aatagccgtg aacaagctgg ttgtgggcac tttttcttcg tgtaaaagtg aagcgcagac
1741 agtgttctct caatcccctt ggggtttcga aggaatagca gagataacac taaaggaggc
1801 ccaaaagagt atttgttcac tgcctttgtc ttgtgtgggt tgtagcttgt tgtcttccaa
1861 ggtcgtattc cttgagacaa caacaaaggc tgctatccat gttggatgtg ggaatggaac
1921 ttcggtccta acagttggga ctactcctgt gagcattgac tgtgtggtaa cgcccctgtc
1981 gcaagtgtgg aggctcgtgt cgcacgtcac cggaagatac actaagcttg ggtttggtgg
2041 aatcggtgga gtgattcatg atattctgca ggcttgtgga tgggttttca catgggactc
2101 atggaaagta attctgatcc tcggaggttt ggttgcgttg ttcatcgtgt ttgatcgtaa
2161 aactgttctc gttgtcatca ttgctagcgc cgttgtctat gtcaaagctg acgttggatg
2221 tggaattgat ttcgaccgga agacctacac ctgtggacgt gggctgttca tttggaaagg
2281 cataggaact tatccggctt cggatcattc ggtagaattc gaatcgtatg atttcctggc
2341 tgcctacctg aaggaacagt tcaaagctga acggaaagtc tgcattgtgt gcgaagattt
2401 ggtacaatgt gaagcggcgc ggaaagctgc cagcgcggtc tatcgagatc ttggacatcc
2461 ttttgtgtat gttaatgtgt cttcatcata tgggagatcg tttgctgaag taccaaagcg
2521 ggtgcacact gtcagtgttg gagttgatgt tgtggaaatg gctatgatgg tttccaataa
2581 taaaccttct gggccatttg gagatttgcc aacaagtatt gtctcttggt caactgcccc
2641 tgaaaacgaa gatcatttag ttctgagggt agtgacgtcg tccacaccat atagacaagt
2701 ctgtggtaaa gcaattggat tccagtatga tttcgtcggg ttcagaagag ctgtgtatgg
2761 atcaaacgtg cagttaaaga tctcgaagaa ggtgtcgata gaatgcccca cgtatttagc
2821 tggaattgca gtaaagaacg accgaactgt tttcactgac ggaatgtttt ggatgtcatc
2881 gcggaaagcc aacgactcat atgcaattga cgaactggag atggaacaat cgcacagatg
2941 tgtatggcca aaccagtaca cacctgatat ggttcaagac ccacgtgaca atgatctgtt
3001 cgtacctccg gaatggggag ggccccgatc aaaagccaac cacattccag gatacaaaat
3061 gcagatcagt tttccatggg acaaagctcc aataaagcta gtggatggaa gtgtgcctgg
3121 aaccatagtg acccagataa gcaagtgtga aggtcgtggt atccctgtca tggtagaccc
3181 tgcggtgaat cccaattggt gttgcaaatc ttgcaccagg attttccatt ttgaagttga
3241 tggaaagttg tactatccga tggagatacg cccagatgtc aaggaggcaa aaaacaaaag
3301 gagtccagta atcgaggaac cactaggaga tgacacggct gagacggtca cggactggct
3361 aagtaagaca tatagagttc catctgccaa tgctgaggat tttctgaacc ccaaattgat
3421 tttgacgaag gcaaacgcaa tggtggggga agtggtaaac cttctttgtc tagcattggc
3481 tatgcaagtc gtgactcaca catggagaca caaatccttg gcgcggtttc acttgtgctg
3541 tttgttgttt ctgctgtttg gtgtacccac cgtctttggc ttcgtaggga tttatacatg
3601 gatgaatatc cttccgatca gccatggctc ggcacggatg tgcaacctga ctatacatct
3661 gtgggctgta ctgcaacacc ggagctcagg catgtttctg tggggacaga cactgaaatt
3721 gcaatttcag acatccttgg ctggacagat gctacttctt accatgcaaa tgctgcatca
3781 ggccatttac gcgcactcat caatgttagg atggggtatc gaagtgttct tatcagttat
3841 tgttatgcag aacttgtaca ccgtagtcga ccatattcac ccgagattga tcgcgtattg
3901 tctgctattc ggatggagga cgggactgtg cataggatgc ggtttcttgt tgatgtactt
3961 gacgaagaga tggatgacta tcgtagcagc atcaccgagc gcgggagggt ggaggtctgg
4021 atatcgagca ttgtgttcgt ccaccctgac tcttttattt accgctgtcg gcgttgtggg
4081 agtcatcgca tcggactacg gtggatatcc gggtgcgtct gcggccatcg cggcttgctt
4141 gatagcagga atcaagatga ctgactttct tgccacgaga ttatcactgg agtttgtctc
4201 gactggacaa tttcccgaag gaacaactat cgagaaggag aaagaaacct acgatgggac
4261 atttcgcgct tcattcacag tggaagggat caagctattg gaccacacgg aaccagtacc
4321 tctggttttt gcgatttcgt atgtggctct cggagctgtg acgtgcaaaa ttcatccagg
4381 gcttggagtg atctatgctg ttgcaatggt tgccacaaac ttaccatctt tgttacaagt
4441 gtacgtgttg tcaatctgta ccaatgcctt tcggtcagat gagttgattg gaactgccat
4501 tgccagcgtt gagccggagt tgtcgaaaga ctttggcaat atcccggacg gcatatatcg
4561 tgtcaacaac catggtattg ctttcaagag ccatcgagga gttggaattg taaaaaacgg
4621 agtattccat acattgatgc acatcacgat gaatgaacca gtgacttggc aaaataagtt
4681 ggttgggccg tacatgggca attctctgaa ggactatctg tgttacggtg gaaactggca
4741 gttgccatca tttgacccca ctgacgaggt tgggataatg gtgtgcaaaa gtgacaggtc
4801 ggtagagtat aagagacatg aagttggcaa aattgatgtt gacggagttc cacacatgta
4861 tttcacaaag gactatgggc gtggaacttc tggatcacca atctttgtca acggagagcc
4921 tgttgcactg tatggatttg ggttttttct ctacaacacg tatcgatctc tagttgttcc
4981 agtcccacga gctgacatag aggctggaga aagtgctgaa gggttggttg aagaaaatag
5041 ctcaatagtg aacaagtttt ttgtggactg gcacccggga aaaggaaaaa cgcggaaagt
5101 gattgtcaag catgttctcg aagccatcag ggactcgcga aggattgtga tcctagcacc
5161 aacaagagta gtcatggctg aaataatgaa agccctcgag gaaagcactc ataaggcgat
5221 ctcgaaaagc atgtcacata caagccataa tggagttaca gttgcttgtc atgcaacatt
5281 cactgacttc attttagctc acggtttgtc tagattcaaa gctcaggagg ttatcatgga
5341 tgaatgtcac tttcttgatc cacggtcaat cgcagcgaga ggtatccttg agcacttggc
5401 gcaaaagcgc ggagttaaag tggtcttcat gagtgcaacg attcccggaa gagagccatc
5461 gattggctca aactatgaga ttgccgagca agctctccag ttcccacggg aggtcacgtc
5521 aaggtggatt ggagatgtgt cggaaggaaa gaccgttgtg tttgttccat ctcacaaagt
5581 tggggacaaa ttagcgttag gaagtccaca gtcaatctca ctgcatcgga acaatttcaa
5641 cactaactac tcgatcgcaa gaagtgatga tatcaagtat gtgtacacaa ctgatatctc
5701 ggagatgggg gcaaatttca atgccacgac ggtggttgat tttcgtgtgg ccattaaacc
5761 aaagattcta aatgactgtg aggttatttt ggcccccacc ccaatcacca ggtcatcgat
5821 ggtccagcga agaggaagag ttggtcggca aagccccggg agatacatct acccagctaa
5881 caaaggtact gaagaagcgg caaatgattt agcttgttgg acggaagccc agatgattct
5941 ggaccagttg gatttaacca tgatggctga ggaagcccct tattcaaatc atccaggagc
6001 ctacaaacta gttgggaaga gctttcaagt gttcaaaaag ctactagagg ataaagatga
6061 cgttcccata tggctgagtt ggaagtgggc tgataatgct gagcaccagt atgccgctct
6121 ctttgaaggg gagagattgg agaatgtacc aaggatggtc aatactagag agtactcatc
6181 tattgaatac aagcccaagt ttattgatgc cagatttgaa cggcttagct gggagcaaag
6241 gaaactagcc atccagttct atatgggaac ccgaagtttt ttgcctgtgg gtcttttctc
6301 caaagttctg actcagatca tccaggcagg cgtagttaac acggcctgga agaaaattgg
6361 cgatgtcggc ttggttttca tggaaggcgg agatccacat tcgaaggatg aatcaatagt
6421 tgcctggacg atcttggttg gagggatgct ttgtgtcatt attctaatga tatgtgtgtg
6481 ggcactgcga attgtcatgc gaatggtttt tggatcgcgc gaaaaacact ctagtgttcc
6541 aacactgtta gctgactctc aaccatacct ggtatgcttg gttcctgtag ccactcatct
6601 cgcgggcgtt ccagttccag tgaccatcgt cgtctttgtc atattgttct tgacatttcc
6661 cttgatttat cgaagtgctg gacaaagaag ctatgtcgac atagatctgg tgaagtggat
6721 tctcgtgggt ggaggcttca taattggagt tatttgctgg gaactgaggc tgctcccaaa
6781 tatcacctcc gacttgcagt caattgccca caaaagaact aggactgatt ccagtggatt
6841 tcagcaggaa agtgactggg ggttttcatg gtttgacttc gcccaaccgg tgccaacaag
6901 tgtcgagttg acttctgtcg tcataactac cttcacgatg gcactgttcc taaaccaaat
6961 tgtgggatgg tcatatgagg cggattggct gaaatcgtac tttgatcata aaggtgtcgg
7021 tcatattatg ggtggttttc gtctggacac aatctcgtgg ggctcagctc tcagctcact
7081 actggggacc ttgtcttacg cttcctgggg agccattata attgggatgg gtggagcaat
7141 gatctatttc tttttcatgg tgaaaatgct gaagtggaat tttacgggag gctcaaccat
7201 cggattagag aataacgcta tgagacagga ccgagaaacg ggcctcaata gaagaccatt
7261 ccacgacagt agaagatcac tgctgtatgg agttgtcatc tttgagtgtg ctctctgggt
7321 gttctgcttt atgagcgttt ttgatttggt cattgcctcg tgtgtttcca catactgtgt
7381 atggatcatc tttaacgcct caagtgagca ccataggaat gttgacctcg ggtccgtgtg
7441 tagtttcgtt ggattattgt acgccacttg tccatcacaa aagtgtgtgc aggttctcat
7501 caggtttgca ttgtccagac tgaacatcac gacaagatca ctggagaaaa gtgccacagg
7561 cggtttgggc cacagatgga agaagatact caatgcaatg tctcaggacg aattcaacgc
7621 gtataggtta tacggagtcg acgaaacaga caagggtgat tacgtctcga gaggaggcct
7681 aaagcttagg gagctgacac tgaagtatgg atggaagcca gaaggaattt gtgttgacct
7741 agggtgtgga agaggaggct ggtcccagca cttggctatg gatccaagag ttacgaggat
7801 cgaagcatac accttgggcg gaacaacgcg tgaaaatcct caacccgtga agacattagg
7861 ccacaatttg attagattca aaacaggtgt aaatgtgtac aacatggccc caacgttcgc
7921 gaacaccatt gtttgtgaca ttggtgagag cgacccaaaa acggaggtgg aagcttcaag
7981 aaccattcgt gtgttgagta ccctaggatc ttggttggag aagaatccca atgcggaatt
8041 cgtttgcaag gtgttgtgcc cgtaccccgt tgaagtctta cggctgttgg agacattcca
8101 gcacaagtat ggtggcagga tcgtacgttc aacgtttagt agaaactctt cagctgaaat
8161 gtattacatc tctggaggac ggaacaacat agtcaaagtc gtgttcacca ctctccatgc
8221 gctaatcgct agacttcgaa caaaaccgga caagattgtc agagaaccaa tccgtttgcc
8281 agttggtacc aggagcgatc caggccacaa ggttaaagac atgaacccaa aaatgattgc
8341 aacaagagta gagaagttga gaaatgagca caaggacacg tggttcattg atagcaatca
8401 tccgtaccaa tcgtttcggt acgtcggttc ttatgtcacc gatgacatca acccaggtgg
8461 acagacagtg aatcctttaa tgcgcaagat gatgtggccg tgggaaatgg ttggaggagt
8521 ggtcaacttc atgatgacgg atgtttcaac atacgctcag caaaaagttt tgagggaaaa
8581 agttgacact ctctcgcccg aaccaccaaa gaacatcaag gccatcaacc ggctcatcac
8641 tgaattccag atccgaagct acttgaaaag gggattgcgt cctcgcatcc tcaccatgga
8701 gcagtatgca gaaaatgtga aaagctcagc ggccattgga tcctggagtt ccgatgtccc
8761 atggaacaat gtgagggctg cccttagtga tgctaatttc catgcactag tggatgagga
8821 acgtcgacta cacctagcag gtgattgtag aatgtgtgtg tacaatacca tgggaaaaaa
8881 ggaaaagaaa ccagcatcta tgggagtagc caaaggatcg agaacaatct ggtacatgtg
8941 gttaggatca aggttcttgg agtatgaggc tcttgggttc ttaaacgagg accattgggt
9001 ttccagggaa aacttggcat gtggtgtagg aggtgtcgga gtcaactatt ttggctatta
9061 tcttcaagag atatccaaaa aagggaagtt cttcattgcc gacgacatcg ctggctggga
9121 taccaggatc aatgagagtg atttggctga tgaagaacat ctcatcatgt cgatgatttc
9181 ggacacaagg caccgagccc tagccacggc gattttcaag tttgcatacc agaacattgt
9241 tgctctcttc cccaggaacc accccgggtt tggaagtgga actgtgatgg acgttgtagc
9301 cagaacagat caacgaggat caggacaagt cgtgacttac gccttgaaca ccattaccaa
9361 tgccaagatt cagcttggga ggatgattga ggctgaggga ttgcttggag ccccggagtc
9421 tgtcatagta aagtggctca acgacaacgg cgaagatagg ctttcagcca tggtggtggc
9481 tggggatgac gtggttgtgg cgacaaacaa cgacaaattc tctcatagtt tggactactt
9541 gaatctcaac ggaaaaatca gaaaggacat tgacccatcc ctcccatcac gagtgcagac
9601 caactgggaa acagtggagt tttgttccca tcactaccac ctaatgactc tccgtgacgg
9661 tcggcgaatc atcgttccat gccgtgacca gaacgaagtc attggccgag gccgaattca
9721 aaagggtggt ttggtgacaa tcgcagacag tgcatgcctg gcaaaggctt atggtcagat
9781 gtgggctctg tactttttcc atcgtcgaga cctacggatg gcgtttatgg ccataacatc
9841 aagcgtcccc gtggactggt ttccggaagg aaggacttca tggtcaatac atcagaacaa
9901 ggagtggatg accacagagg acatgttgag agtgtggaat acggtttgga ttcatgacaa
9961 caattggatg gaggacaaaa ctgaagtgac cgcctggaaa gatataccct atctaccaaa
10021 atctattgac atcaagtgtg gaagccaaat aggaagtaag gatcgagcta cttggtcacg
10081 tgaattgcct tcaactgtca tggcaattag gaagattcta gaccacgaga ccaggatgga
10141 aaatgtctac aaagattttt tgagtggtat ggggcggttc agggaggaca atgatccaat
10201 ggcggccgga gttcggtttt aatacttgac tagtaaaaat ttttacgctt ttgacgacga
10261 tttttaaata ctttgaccca ttgcagcaga gatttatctc gggggagtta cgcccctcca
10321 ttgccagtag agtttgcatg tctctataaa catgacgttc tgactgacta
//
