LOCUS NC_038922 2428 bp RNA linear VRL 24-AUG-2018
DEFINITION Avian sarcoma virus CT10 genomic sequence.
ACCESSION NC_038922
VERSION NC_038922.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq; complete genome; crk oncogene; gag gene; gag-crk fusion
protein.
SOURCE Avian sarcoma virus CT10
ORGANISM Avian sarcoma virus CT10
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus.
REFERENCE 1 (bases 1 to 2428)
AUTHORS Mayer,B.J., Hamaguchi,M. and Hanafusa,H.
TITLE A novel viral oncogene with structural similarity to phospholipase
C
JOURNAL Nature 332 (6161), 272-275 (1988)
PUBMED 2450282
REFERENCE 2 (bases 1 to 2428)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (24-AUG-2018) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 2428)
AUTHORS Mayer,B.J.
TITLE Direct Submission
JOURNAL Submitted (14-MAR-1988) Mayer B.J., The Rockefeller University,
1230 York Avenue, New York, NY 10021, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to Y00302.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..2428
/organism="Avian sarcoma virus CT10"
/mol_type="genomic RNA"
/strain="CT10"
/db_xref="taxon:11878"
gene 379..1701
/locus_tag="D1T39_gp1"
/db_xref="GeneID:37619590"
CDS 379..1701
/locus_tag="D1T39_gp1"
/codon_start=1
/product="p47(gag-crk)"
/protein_id="YP_009508242.1"
/db_xref="GOA:P05433"
/db_xref="InterPro:IPR000980"
/db_xref="InterPro:IPR001452"
/db_xref="InterPro:IPR004028"
/db_xref="InterPro:IPR010999"
/db_xref="InterPro:IPR012344"
/db_xref="UniProtKB/Swiss-Prot:P05433"
/db_xref="GeneID:37619590"
/translation="MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSD
LYSPRSWDPITAALTQRAMELGKSGELKTWGLVLGALEAAREEQEQVTSEQAKFWLGL
GGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYYCG
AAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPRGAEQPRAGRGAGHRGLR
RPAGRGQRVRPAGGAALMAGQFDSEDRGSWYWGRLSRGDAVSLLQGQRHGTFLVRDSG
SIPGDFVLSVSESSRVSHYIVNSLGPAGGRRAGGEGPGAPGLNPTRFLIGDQVFDSLP
SLLEFYKIHYLDTTTLIEPVSRSRQNSGVILRQEEVEYVRALFDFKGNDDGDLPFKKG
DILKIRDKPEEQWWNAEDMDGKRGMIPVPYVEKCRPSSASVSTLTGGR"
mat_peptide 379..1002
/locus_tag="D1T39_gp1"
/product="gag polypeptide"
/protein_id="YP_009509090.1"
misc_feature 382..639
/locus_tag="D1T39_gp1"
/note="Retroviral M domain; Region: Retro_M; pfam02813"
/db_xref="CDD:280904"
misc_feature 1096..1452
/locus_tag="D1T39_gp1"
/note="Src homology 2 domain found in cancer-related
signaling adaptor protein CRK; Region: SH2_CRK_like;
cd09926"
/db_xref="CDD:198180"
misc_feature order(1141..1143,1195..1197,1258..1260,1264..1266)
/locus_tag="D1T39_gp1"
/note="phosphotyrosine binding pocket [polypeptide
binding]; other site"
/db_xref="CDD:198180"
misc_feature order(1261..1263,1396..1398)
/locus_tag="D1T39_gp1"
/note="hydrophobic binding pocket [polypeptide binding];
other site"
/db_xref="CDD:198180"
misc_feature 1489..1653
/locus_tag="D1T39_gp1"
/note="N-terminal Src Homology 3 domain of Ct10 Regulator
of Kinase adaptor proteins; Region: SH3_CRK_N; cd11758"
/db_xref="CDD:212692"
misc_feature order(1507..1515,1522..1524,1582..1584,1588..1593,
1633..1635,1639..1644)
/locus_tag="D1T39_gp1"
/note="C-terminal SH3 interface [polypeptide binding];
other site"
/db_xref="CDD:212692"
misc_feature order(1507..1509,1513..1515,1534..1536,1582..1584,
1588..1593,1633..1635,1639..1644)
/locus_tag="D1T39_gp1"
/note="peptide ligand binding site [polypeptide binding];
other site"
/db_xref="CDD:212692"
misc_feature 1002..1688
/locus_tag="D1T39_gp1"
/product="transduced crk polypeptide"
ORIGIN
1 gccattttac ctcccaccac attggtgtgc acctgggttg atggccggac cgttgagtcc
61 ctaacgattg cgaacacctg catgaagcga aaggcttcat ttggtgaccc cgacgtgatc
121 gttagggaat agtggtcggc cacagacggc gtggcgatcc tgtcctcatc cgtctcgctt
181 attcggggag cggacgatga ccctagtaga gggggctgcg gcttaggagg gcagaagctg
241 agtgacgtcg gagggagctc tactgcaggg gccaagataa cctaccgaga actcagagag
301 tcgttggaag acgggaagga agcccgacga ctgagcagtc caccccaggc gtgattctgg
361 tcgcccggtg gatcaagcat ggaagccgtc ataaaggtga tttcgtccgc gtgtaaaacc
421 tattgcggga aaacctctcc ttctaagaag gaaatagggg ccatgttgtc cctgttacaa
481 aaggaagggt tgcttatgtc tccctcagac ttatattccc cgaggtcctg ggatcccatt
541 accgcggcac tcacccagcg ggcaatggaa cttgggaaat cgggagagtt aaaaacctgg
601 ggattggttt tgggggcatt ggaagcggct cgagaggaac aggaacaggt tacatctgag
661 caagcaaagt tttggttggg attaggggga gggagggtct ctcccccagg tccggaatgc
721 atcgagaaac cagcaacgga gcggcgaatc gacaaggggg aggaagtggg agaaacaact
781 gtgcagcgag atgcgaagat ggcgccggag gaaacggcca cacctaaaac cgttggcaca
841 tcctgctatt attgcggagc agctattggc tgtaattgcg ccacagcctc ggctcctcct
901 cctccttatg tggggagtgg tttgtatcct tccctggcgg gggtgggaga gcagcagggc
961 caggggggtg acacacctcg gggggcggaa cagccaaggg ctgggcgcgg agcggggcac
1021 cgcgggctgc ggcggcccgc ggggcggggg cagcgagtgc ggcctgcggg tggggcggcc
1081 ctcatggccg ggcagttcga ctccgaggac cgggggagct ggtactgggg gcggctgagc
1141 cggggcgacg cggtgtcgct gctgcagggg caacgccacg ggaccttcct ggtgcgcgac
1201 tcgggctcca tccccggcga cttcgtgctc tcggtgtccg agagctcccg cgtctcgcac
1261 tacatcgtca acagcctggg gccggcggga ggccggaggg ccggcggcga gggccctggg
1321 gccccggggt tgaatcccac cagatttcta ataggtgacc aggtgtttga ttctttgcca
1381 tctttactgg aattctacaa aatacactat ttggacacta caaccttgat agaaccagtt
1441 tcccgatcca ggcagaacag tggcgttatc ctcaggcagg aggaagttga atatgtgcga
1501 gctctctttg actttaaggg aaacgatgac ggagatcttc catttaagaa aggagacata
1561 ctgaaaatcc gggataaacc tgaagagcaa tggtggaatg cagaagacat ggatggaaag
1621 aggggaatga tacctgttcc ttacgtcgag aagtgtagac cttcctctgc ttcagtatct
1681 actctgactg gaggtcgctg agtagtgcgc gagcaaaatt taagctacaa cagggcaagg
1741 cttggccgat aattgcatga agaaatttgc ttaggcgctt tgcgctgctc cgcgatgtac
1801 gggttaatgc ttctgtagaa attgtttggc attaggcgta ttgcgctgct ccgcgatgta
1861 cgggttaggt ataatatgaa gtttgactga ggggaccatg atgtgtatag gcgtcaagcg
1921 gggcttcggt tgtacgcaga caggggtccc ctcagaaagt agaggtgctt ctgcataggg
1981 agggggaaat gttgccacat agtcatcgtt gcataagtat tgccacatag tcatcgttac
2041 ataagggtca gaggctgctt gaagtcctaa aaagggaaag gcagaacatc tggaatgcca
2101 ttggtagcag ctagatcacc cgatgggtgt aactgaaaga tcattggtga caggatatcg
2161 cctcatgggc agggctaaag ctatgcatga ttatataagt acccttatgt cacgatgaca
2221 cagcaatatg ccttataagg aaaaaaaggc actgtacacg ttgattggtg gaagtaaggt
2281 ggtatgatcg tggtatgatc gtgccttatt aggaaggcaa cagacgggtc tgacatggat
2341 tggacgatct ccttagttcc gcattgcaga gatagtgtat ttaagtgcct agcctgatac
2401 aataaacgcc attttacctc ccaccaca
//
