LOCUS NC_039194 16236 bp RNA linear VRL 24-AUG-2018
DEFINITION Avian paramyxovirus 6 strain APMV-6/Goose/FarEast/4440/2003,
complete genome.
ACCESSION NC_039194
VERSION NC_039194.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Avian metaavulavirus 6 (APMV-6)
ORGANISM Avian metaavulavirus 6
Viruses; Riboviria; Orthornavirae; Negarnaviricota;
Haploviricotina; Monjiviricetes; Mononegavirales; Paramyxoviridae;
Avulavirinae; Metaavulavirus; Metaavulavirus hongkongense.
REFERENCE 1 (bases 1 to 16236)
AUTHORS Usachev,E.V. and Prilipov,A.G.
TITLE APMV-6 isolated from domestic goose at Far East of Russian
Federation
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 16236)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (24-AUG-2018) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 16236)
AUTHORS Usachev,E.V. and Prilipov,A.G.
TITLE Direct Submission
JOURNAL Submitted (22-APR-2007) Molecular Genetic, Ivanovsky Virology
Institute, Gamalei, Moscow 123098, Russian Federation
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to EF569970.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..16236
/organism="Avian metaavulavirus 6"
/mol_type="genomic RNA"
/strain="APMV-6/Goose/FarEast/4440/2003"
/host="domestic goose"
/db_xref="taxon:2560316"
/country="Russia"
/collection_date="2003"
gene 128..1525
/gene="NP"
/locus_tag="D1Y17_gp1"
/db_xref="GeneID:37626931"
CDS 128..1525
/gene="NP"
/locus_tag="D1Y17_gp1"
/codon_start=1
/product="nucleocapsid protein"
/protein_id="YP_009512944.1"
/db_xref="GeneID:37626931"
/translation="MSSVFTDYAKLQDALVAPSKRKVDSAPSGLLRVGIPVCVLLSED
PEERWSFVCFCMRWVVSDSATEAMRVGAMLSILSAHASNMRSHVALAARCGDADINIL
EVEAIDHQNQTIRFTGRSNVTDGRARQMYAIAQDLPPSYNNGSPFVNRDIEDNYPTDM
SELLNMVYSVATQIWVAAMKSMTAPDTSSESEGRRLAKYIQQNRVIRSTILAPATRGE
CTRIIRSSLVIRHFLITEIKRATSMGSNTTRYYATVGDAAAYFKNAGMAAFFLTLRFG
IGTKYSTLAVSALSADMKKLQSLIRVYQSKGEDGPYMAFLEDSDLMSFAPGNYPLMYS
YAMGVGSILEASIARYQFARSFMNDTFYRLGVETAQRNQGSLDENLAKELQLSGAERR
AVQELVTSLDLAGEAPVPQRQPTFLNDQEYEDDPPARRQRIEDTPDDDGASQAPPTPG
AGLTPYSDNASGLDI"
misc_feature 338..1492
/gene="NP"
/locus_tag="D1Y17_gp1"
/note="Paramyxovirus nucleocapsid protein; Region:
Paramyxo_ncap; pfam00973"
/db_xref="CDD:395775"
gene 1687..2979
/gene="P"
/locus_tag="D1Y17_gp2"
/db_xref="GeneID:37626925"
CDS 1687..2979
/gene="P"
/locus_tag="D1Y17_gp2"
/codon_start=1
/product="phosphoprotein"
/protein_id="YP_009512945.1"
/db_xref="GeneID:37626925"
/translation="MDFSNDQEIAELLELSSDVIKSIQHAETQPAHTVGKSAIRKGNT
SELRAAWEAETQPTQTENKSEEHPEQTARDPDSKGNTGNSQPRSNAEETPQSESHDRQ
VAAPPPDTTIGVNGTNGLEAALKKLEKQGKGPGKGQVDRNTPQRDPTTASGSKKGKGG
EPRSNALHQGYPQGTNLILPTQRPSHARLAQQASQEITRHALQPQDSGGIEGNSPFLG
DTASASWPSGATQSVHLSHLNPEHSNAFAGDALEYASTVATIVETLKFVVSRLEALEN
RVAELTKFVSPIQQIKADMQIVKTSCAVIEGQLATVQILEPGHSSIRSLEEMKQYTKP
GIVVQTGMTQDISAVMRDGTIVKDALARPVNPDKWSATINAQSTTMKVTQEDIKTVYT
LLDNFGITGPKRAKIEAELANVSDRDALVRIKKRVMNA"
misc_feature 1687..1860
/gene="P"
/locus_tag="D1Y17_gp2"
/note="N-terminal region of Paramyxovirinae phosphoprotein
(P); Region: Soyouz_module; pfam14313"
/db_xref="CDD:316803"
misc_feature 2506..2970
/gene="P"
/locus_tag="D1Y17_gp2"
/note="C-terminal domain of Measles virus phosphoprotein
and related proteins; Region: MEV_P-protein-C_like;
cl03936"
/db_xref="CDD:413868"
gene 3235..4335
/gene="M"
/locus_tag="D1Y17_gp3"
/db_xref="GeneID:37626926"
CDS 3235..4335
/gene="M"
/locus_tag="D1Y17_gp3"
/codon_start=1
/product="matrix protein"
/protein_id="YP_009512946.1"
/db_xref="GeneID:37626926"
/translation="MATSELNLYIDKDSPQVRLLAFPIIMKPKENGVRELQPQLRTQY
LGDITGGKKSAIFVNCYGFVEDHGGRDSGFSPISEESKGSTVTAACITLGSIEYDSDI
KEVAKACYNLQVSVRMSADSTQKVVYTINAKPALLFSSRVVRAGGCVVAAEGAIKCPE
KMTSDRLYKFRVMFVSLTFLHRSSLFKVSRTVLSMRNSALIAVQAEVKLGFDLPLDHP
MAKYLSKEDGQLFATVWVHLCNFKRTDRRGVDRSVENIRNKVRAMGLKLTLCDLWGPT
LVCEATGKMSKYALGFFSETKVGCHPIWKCNSTVAKIMWSCTTWIASAKAIIQASSAR
ALLTSEDIEAKGAISTDKKKTDGFNPFIKTAK"
misc_feature 3256..4275
/gene="M"
/locus_tag="D1Y17_gp3"
/note="Viral matrix protein; Region: Matrix; pfam00661"
/db_xref="CDD:395535"
gene 4598..6265
/gene="F"
/locus_tag="D1Y17_gp4"
/db_xref="GeneID:37626927"
CDS 4598..6265
/gene="F"
/locus_tag="D1Y17_gp4"
/codon_start=1
/product="fusion protein"
/protein_id="YP_009512947.1"
/db_xref="GeneID:37626927"
/translation="MGARLGPLTMAPGRYVIIFNLILLHRAVSLDNSRLLQQGIMSAT
EREIKVYTNSITGSIAVRLIPNLPQEVLKCSAGQIKSYNDTLNRIFTPIKANLERLLA
TPSMLEDNQNPAPEPRLIGAIIGTAALGLATAAQVTAALALNQAQDNAKAILNLKESI
TKTNEAVLELKDATGQIAIALDKTQRFINDNILPAINNLTCEVAGAKVGVELSLYLTE
LSTVFGSQITNPALSTLSIQALMSLCGNDFNYLLNLMGAKHSDLGALYEANLINGRII
QYDQASQIMVIQVSVPSISSISGLRLTELFTLSIETPVGEGKAVVPQFVVESGQLLEE
IDTQACTLTDTTAYCTIVRTKPLPELVAQCLRGDESRCQYTTGIGMLESRFGVFDGLV
IANCKATICRCLAPEMIITQNKGLPLTVISQETCKRILIDGVTLQIEAQVSGSYSRNI
TVGNSQIAPSGPLDISSELGKVNQSLSNVEDLIDQSNQLLNRVNPNIVNNTAIIVTIV
LLVLLVLWCLALTISILYVSKHAVRMIKTVPNPYVMQAKSPGSATQF"
misc_feature 4688..6103
/gene="F"
/locus_tag="D1Y17_gp4"
/note="Fusion glycoprotein F0; Region: Fusion_gly;
pfam00523"
/db_xref="CDD:395418"
gene 6542..6970
/gene="SH"
/locus_tag="D1Y17_gp5"
/db_xref="GeneID:37626928"
CDS 6542..6970
/gene="SH"
/locus_tag="D1Y17_gp5"
/codon_start=1
/product="small hydrophobic protein"
/protein_id="YP_009512948.1"
/db_xref="GeneID:37626928"
/translation="MRPQVAVWALRLLATGLAMISLVFCLNQVIMQVLIRDIGDLLTS
SEIKTTRETLREHLSSITLFMSFALTCSISGCVLSLVALYPSKNINGTNTQPQVEEAR
SENLSHSSMHTINRPATPPPPYYVAIQLSAEMQPGYHPGD"
gene 7122..8963
/gene="HN"
/locus_tag="D1Y17_gp6"
/db_xref="GeneID:37626929"
CDS 7122..8963
/gene="HN"
/locus_tag="D1Y17_gp6"
/codon_start=1
/product="hemagglutinin-neuraminidase"
/protein_id="YP_009512949.1"
/db_xref="GeneID:37626929"
/translation="MASSSDMRQSQATLYEGDPNSKRTWRTVYRVITILLDITVLCVG
IVAVVRMSTITTKDIDNSISSSITSLSADYQPIWSDTHQKVNSIFKEVGITIPVTLDK
MQVEMGTAVNIITDAVRQLQGVNGSAGFSITNSPEYSGGIDTLIYPLNSLNGKALAVS
DLLEHPSFIPAPTTSHGCTRIPTFHLGYRHWCYSHNTIESGCHDAEESIMYVSMGAVG
VGHRGRPVFTTSAATILDDGRNRKSCSIIANPNGCDVLCSLVKQTENEDYADPTPTPM
IHGRLHFNGTYTESELNPGLFNNHWVAQYPAVGSGVVSHGKLFFPLYGGISPKSKLFN
ELKSFAYFTHNAELKCENLTERQKEDLYNAYRPGKIAGSLWAQGVVTCNLTNLADCKV
AIANTSTMMMAAEGRLQLVQDRIVFYQRSSSWWPVLIYYDIPISDLISADHLGIVNWT
PYPQSKFPRPTWTKGVCEKPAICPAVCVTGVYQDIWVVSIGSQSNETVVVGGYLDAAA
ARQDPWIAAANQYNWLVRRRLFTSQTEAAYSSTTCFRNTKQDRVFCLTIMEVTDNLLG
DWRIAPLLYEVTVADKQQGNRNYAPMRRMGTDKFQYYTPGDKYTPQH"
misc_feature 7617..8849
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Hemagglutinin-neuraminidase (HN) of parainfluenza
virus 5, Newcastle disease virus, and related
paramyxoviridiae; Region: HN; cd15469"
/db_xref="CDD:271233"
misc_feature order(7629..7646,7716..7718,7752..7754,7779..7781,
7785..7787,7821..7823,7827..7829,8805..8816,8826..8828,
8832..8840)
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:271233"
misc_feature 7656..7832
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Sialidase propeller 1 [structural motif]; Region:
Sialidase propeller 1"
/db_xref="CDD:271233"
misc_feature order(7659..7661,7731..7733,8334..8336,8379..8381,
8649..8651,8733..8735,8796..8798)
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="active site"
/db_xref="CDD:271233"
misc_feature order(7659..7661,7911..7913,8034..8036,8088..8090,
8226..8231,8334..8336,8379..8381,8385..8387,8553..8555,
8649..8651,8733..8735)
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="receptor binding site [chemical binding]; other
site"
/db_xref="CDD:271233"
misc_feature 7839..7997
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Sialidase propeller 2 [structural motif]; Region:
Sialidase propeller 2"
/db_xref="CDD:271233"
misc_feature 8022..8321
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Sialidase propeller 3 [structural motif]; Region:
Sialidase propeller 3"
/db_xref="CDD:271233"
misc_feature 8325..8486
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Sialidase propeller 4 [structural motif]; Region:
Sialidase propeller 4"
/db_xref="CDD:271233"
misc_feature 8559..8711
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Sialidase propeller 5 [structural motif]; Region:
Sialidase propeller 5"
/db_xref="CDD:271233"
misc_feature 8727..8849
/gene="HN"
/locus_tag="D1Y17_gp6"
/note="Sialidase propeller 6 [structural motif]; Region:
Sialidase propeller 6"
/db_xref="CDD:271233"
gene 9278..16003
/gene="L"
/locus_tag="D1Y17_gp7"
/db_xref="GeneID:37626930"
CDS 9278..16003
/gene="L"
/locus_tag="D1Y17_gp7"
/codon_start=1
/product="large polymerase protein"
/protein_id="YP_009512950.1"
/db_xref="GeneID:37626930"
/translation="MDPQVQIHHIIKPECHLNSPVVEKKLTLLWKLTGLPLPPDLNSC
VTHKDVTWDEVLRLEANLTKELRQLVRGLTNRMHERGEFIDSYKPLCHPRTLSWLTNI
SLIKSDNILAGHKKMLVRIGGMLHEQTDQLFVTLGRKLAGDPCLFHQLGHLAGCPPNS
RFEEQVGGCSLWSPISDPALVTGGEYANCVYAWYLIRQTMRYMALQRKQTRVQSQQNV
LIGSDTIVGIHPELVIITGIRDRTFTCLTFDMVLMYADVVEGRAMTKLVALTEPTMVE
VIQRVEKLWFLVDSIFEEIGGAGYNIVASLESLAYGAVQLWDKSLEHAGEFFSFNLTE
IRSELENHLDPGMAFRVVEQVRLLYTGLSVNQAGEMLCILRHWGHPLLCAVKAAKKVR
ESMCAPKLTSLDTTLKVLAFFIADIINGHRRSHSGLWPSVRQESLVSPLLQNLYRESA
ELQYAIVLKHYREVSLIEFQKSIDFDLVEDLSVFLKDKAICRPKSNWLAVFRKSLLPG
HLKDKLQSEGPSNRLLLDFLQSSEFDPAKEFEYVTSLEYLQDPEFCASYSLKEREVKT
DGRIFAKMTRKMRNCQVLLESLLACHICDYFKENGVVQEQISLTKSLLAMSQLAPRVS
EYQGRVLRSTDRCSRATATPGQDTSPGEGVRRRKTIIASFLTTDLQKYCLNWRYTVVK
PFAQRLNQLFGIPHGFEWIHLRLMNTTMFVGDPHNVPQFSSTHDLESQENDGIFIVSP
RGGIEGLCQKMWTMISIAAIHLAATESGCRVASMVQGDNQAIAITTEIEEGEDASVAS
IRLKEISERFFRVFREINRGIGHNLKVQETIHSESFFVYSKRIFFEGKILSQLLKNAS
RLVLVSETVGENCVGNCSNISSTVARLIENGLDKRVAWGLNIMMIVKQILFDIDFSLE
PEPSQGLIHAIRQDPNNIKNISITPAQLGGLNFLALSRLFTRNIGDPVSSAMADMKFY
IQVGLLSPHLLRNAIFREPGDGTWTTLCADPYSLNQPYVQLPTSYLKKHTQRMLLTAS
TNPLLQGTRVENQYIEEERLAKFLLDRELVMPRVAHTVFETTVAGRRKHLQGLIDTTP
TIIKYALHHHPISFKKSMLISSYSADYIMSFIDTIATVEYPKRDTMKLWNRGLIGVDT
CAVTLADYARTYSWWEILKGRSIKGVTTPDTLELCSGSLIEQGHPCAQCTMGDESFSW
FFLPGNIDIERPDFSRVAQRIAYVGSKTEERRAASLTTIKGMSTHLRAALRGASVYIW
AYGDSDKNWDDATKLANTRCVISEDHLRALCPIPSSANIQHRLMDGISVTKFTPASLA
RVSSYIHISNDRHQSRIDGQVIESNVIFQQVMLLGLGIFETFHPLSHRFVTNPMTLHL
HTGYSCCIREADNGDFLESPASVPDMTITTGNKFLFDPMPIQDDDAAKLQVSSFKYCE
MGLEVLDPPGLVTLLSLVTARISIDTSIGESAYNSIHNDAIVSFDNSINWISEYTYCD
LRLLAVAMAREFCDNLSYQLYYLRVKGRRAIRDYIRQALSRIPGLQLANIALTISHPG
IWARLRLIGAVSAGNSPISATVNYPAAVCELILWGYDQYTAQLLDGYELEIIVPNYKD
DDLNRKVEHILARRACLLSLLCEYPGKYPNIKDLEPIEKCTALSDLNKLWMATDHRTR
ECFSGISQIFDSPKLNPFITNLYFLSRKLLNAIRSSTDCRAYVENLYEDIDIELTSLT
EVVPLGEDDQMITGPLRFDLELKELTPDFTITWCCFDSTAALMSRCINHATEGAERYI
RRTVGTASTSWYKAAGILTTPGFLNLPKGNGLYLAESSGAIMTVMEHLVCSNKIWYNT
LFSNELNPPQRNFGPNPIQFEESIVGKHIAAGIPCKAGHVQEFEVLWREVDEETDLTS
MRCVNFIMSKVEQHSCHIVCCDLELAMGTPLEVAQSAYTHIITLALHCLMISGKLVLK
LYFSQNALLHHVLSLLLVLPFHVTIHTNGYCSHRGSEGYIIATRTGVALGSNVSQVLG
SVTEMVRKGQTLVPVKVLTAISNGFKTVSSSLGRLRGELYSPSCSIPQSATDMFLIQL
GGKVQSDWNTNSRGYRVGDTELVLQDIISILSTLLKEIIHVRESRESVDRVLLLGAYN
LQVSGKVRTMAAAATRNILHLHIVRLIGDSMSNIRRLVPLLDKGFIVISDMYSVKDFL
RKTESPKYFLNKLGKSEIAQIFEVESKIILSRAEIKNILKMIGIVAKQHSE"
misc_feature 9317..12646
/gene="L"
/locus_tag="D1Y17_gp7"
/note="Mononegavirales RNA dependent RNA polymerase;
Region: Mononeg_RNA_pol; pfam00946"
/db_xref="CDD:395756"
misc_feature 13022..15988
/gene="L"
/locus_tag="D1Y17_gp7"
/note="mRNA capping enzyme, paramyxovirus family; Region:
paramyx_RNAcap; TIGR04198"
/db_xref="CDD:275046"
ORIGIN
1 accaaacaag gaaaccatat gcttggggaa tttacgagaa cgcttataaa atcgtgaggg
61 ggaagctggt ggactccggg tccggagtcg gtggacctga gtctagtagc ttccctgctg
121 tgccaagatg tcgtcggtgt tcactgacta cgctaagctg caagatgccc ttgtggcccc
181 ttcaaaaagg aaggtggata gtgcaccaag cggattgtta agggttggga tccctgtgtg
241 tgtcctactc tccgaggatc ctgaagaacg atggagcttt gtttgctttt gcatgaggtg
301 ggtggtgagc gattcagcca cagaggcaat gcgtgttggt gcaatgctat ctatcctcag
361 cgcacacgcc agcaacatgc ggagccatgt cgcacttgca gcaagatgtg gcgacgccga
421 catcaacata cttgaggttg aggcaattga ccaccaaaac cagaccattc gtttcactgg
481 gcgcagcaat gtgactgacg ggagagcacg ccagatgtat gcgattgccc aagatctgcc
541 tccctcctat aacaatggta gcccttttgt aaatagagac attgaggaca attatccgac
601 cgacatgtct gagctgctca acatggttta cagtgttgca actcaaatct gggtggcagc
661 tatgaagagc atgactgctc cagacacatc ctcagagtct gaagggaggc ggttggccaa
721 atacatccag caaaacagag tgatccggag tacgatttta gctcctgcaa ctcgcggtga
781 atgcacccgg ataatacgga gctccctagt catccgccac tttctaataa ctgagatcaa
841 gcgtgccaca tcaatgggtt ccaacacgac gagatattat gccacagttg gggatgctgc
901 agcttacttc aagaacgcgg gtatggctgc attcttctta actctgcggt ttggaattgg
961 gaccaagtac tccacacttg cagtttcagc gctgtccgcc gacatgaaga aactccagag
1021 cttgatccga gtataccaga gcaaaggtga ggatggaccc tatatggcat ttctggaaga
1081 ctccgacctt atgagcttcg cccctggaaa ctatccactc atgtattcat atgcaatggg
1141 agtagggtcc attcttgagg caagtattgc tcgatatcag tttgctcgat cattcatgaa
1201 tgacacgttc tatcgattgg gtgttgaaac tgcacaacga aaccaaggtt cacttgatga
1261 gaatctagcg aaggagctgc aactatctgg ggccgaacgg agggcagtgc aggaacttgt
1321 gaccagcctg gacctagctg gagaggcccc agtgccccag cgtcaaccaa cattcctcaa
1381 tgaccaggag tatgaggatg atccccccgc caggagacag agaattgagg atactccaga
1441 cgatgacgga gccagtcaag ctccacccac accaggagca ggtctcaccc catactctga
1501 taatgccagt ggcctggaca tctaaacgac cagtacttag tataacaatt gatcaaggtt
1561 aatccaaagt atgcaaatcc aatactccaa tcgataacaa gatcacatgt agactttaag
1621 aaaaaacaag ggtgaggggg aagttcctgg tacgcgggct gggcccatag tgactcagct
1681 agcaccatgg acttctccaa tgaccaggag attgcagaat tactcgagct gagttcggat
1741 gtgataaaga gcatccaaca tgccgagacc cagccagcac acactgtcgg caaatctgcc
1801 attcggaaag gaaatacatc cgagctgcga gcagcctggg aagccgagac acaaccaacc
1861 caaacagaaa acaagtctga ggaacaccca gagcaaactg cccgggatcc cgacagcaag
1921 ggcaacacag gaaattcgca accacgatcc aacgcagagg agacacccca atcagaaagt
1981 cacgacaggc aagtcgctgc tccaccccca gacaccacaa taggggttaa cgggaccaat
2041 gggcttgaag ctgctctaaa aaagctagaa aaacaaggga aaggtcccgg gaaaggccaa
2101 gtggatcgca acacccctca gagagatcca accactgcct cgggttcaaa aaaggggaaa
2161 gggggcgagc caaggagcaa tgccctccat cagggttacc cacaggggac caacttgatc
2221 ctgcccactc agaggccctc tcatgccaga ctggcgcagc aagcatcaca ggagataact
2281 cgccatgcgc tgcaacccca ggactccggc ggcatagaag ggaattctcc atttcttgga
2341 gacacggcca gtgcatcctg gccgagtggt gcaacccagt ctgtgcacct gtcacacctg
2401 aacccagagc attcaaatgc atttgcggga gatgccctcg agtatgcatc aactgtcgca
2461 acgatagtgg agactctgaa atttgtagtt agcaggttag aagcacttga aaatagggtg
2521 gcggagctca ccaaatttgt ctctcccatt cagcaaatca aagcagacat gcagattgta
2581 aagacatcct gcgctgtcat tgagggccaa cttgccacag tgcaaatatt ggagccgggc
2641 cactcatcga ttcgctcact tgaggagatg aagcaataca ccaagccagg aattgtcgtc
2701 caaacaggga tgactcaaga cataagcgcc gtcatgaggg acggcacgat cgtaaaagat
2761 gctcttgctc gcccagttaa tccggacaag tggtcagcaa caatcaatgc tcaatcaaca
2821 acaatgaagg taacccaaga agatataaag acggtgtata cactattgga caattttggc
2881 atcactggcc caaaaagagc gaaaattgag gcggaattgg ctaatgtcag tgaccgggac
2941 gcactagtaa ggattaagaa acgtgttatg aatgcataag cagccaaaaa atcacaacaa
3001 ttagtacaga tggcctccca atgtcacatc atgattctat tgtcaaatca cagcattctt
3061 tcttcctgat cacacccaac aatttgcttt ggacaccctt gacactgatt aataaaaaag
3121 tgagggggaa ctggtggtgt ccggactggg caacccaggg tcacccggtc cgaaccaaac
3181 acccgccagt tcctccaccg gcacagcgca ccactgactg caccgacccc aaccatggcc
3241 acgtcagaac tcaacctcta tatcgacaag gactcacccc aggtgagatt gctagcattc
3301 cccatcatca tgaaacccaa agaaaatggg gttagagagc tgcaaccgca actgaggact
3361 cagtacctcg gtgacatcac cggaggaaag aaaagcgcga tatttgtgaa ttgctatggg
3421 ttcgttgaag atcacggggg gcgagacagc ggattctcac ccatcagtga agaatccaaa
3481 ggatcgacag tcactgcagc ctgcatcact cttggcagca tcgagtatga tagtgacatc
3541 aaggaagtgg caaaggcctg ctataatctt caggtgtcag ttaggatgtc cgctgattca
3601 actcagaagg ttgtttacac aatcaatgct aaacctgcac tgttgttctc ctcccgtgtt
3661 gtcagagctg ggggttgtgt ggttgcagca gagggtgcaa tcaagtgccc cgagaagatg
3721 acatccgatc gcctttacaa gttccgcgta atgtttgttt cattgacctt cttacatcgc
3781 agcagccttt tcaaagttag ccgtacggtg ctgtcaatga ggaattctgc tctaatagca
3841 gtacaggccg aagtgaagct gggattcgat ctgccactag accatccaat ggcaaaatat
3901 ctgagcaaag aggatggaca gctctttgcg actgtgtggg tacatttgtg caacttcaag
3961 cgcacagaca gacggggagt agaccgatcg gtggagaaca tcagaaacaa agtacgggcc
4021 atggggctga agctcacctt gtgtgatctg tggggtccca cacttgtttg tgaagctaca
4081 gggaagatga gcaagtacgc gctaggtttc ttctcggaga ccaaggttgg ctgtcatcca
4141 atctggaaat gcaactcgac tgtcgcgaag atcatgtggt catgcacaac ctggatcgca
4201 tcagcaaagg ccatcataca ggcctcctct gctcgtgccc tgttgacatc agaggacata
4261 gaagccaagg gagccatctc cactgacaaa aagaaaacag atgggtttaa tcccttcatc
4321 aagacagcaa agtagtcatc tgaatctcat cagtgaaccc actggcatat gttcagctgt
4381 gccttccttg ataatcacta aatcaatacg cagagtgctc tttgattaag atctcgattg
4441 ttccaataag tggatcattt atactttgaa gattgaactt cctaactatt ccttccttag
4501 aagtccagtc atattaatca aaaaaatcag tttgctggta aagtcgtata ctgcaggatc
4561 caatacctct caccaatgag tagctgaggg ggaaggcatg ggagcccgac tggggccctt
4621 aacaatggca cccggccggt atgtgatcat tttcaatctc atccttctcc atagggccgt
4681 ctcactagac aattcaaggt tactgcagca ggggatcatg agtgcgaccg agagagaaat
4741 taaagtgtac acgaactcca taaccggaag tattgctgtg agattaattc ccaacttacc
4801 tcaagaagtg cttaagtgct ccgctgggca gatcaaatcg tacaatgaca cccttaaccg
4861 aatttttaca cctattaagg cgaaccttga gaggttactg gccacaccaa gtatgcttga
4921 agacaaccag aaccctgctc cagaacctcg tctgattgga gcaattatag gcacagcagc
4981 actggggttg gcaacagcag ctcaggttac agctgccctt gcccttaacc aggcccagga
5041 taatgccaag gccatcttga acctcaaaga gtccataaca aagacaaacg aggctgtgct
5101 tgagcttaaa gatgcaacag ggcaaattgc aatagcgcta gataagactc aaagattcat
5161 aaatgacaat atcttaccgg cgattaataa tctgacatgt gaagtagcag gtgctaaagt
5221 aggtgtggaa ctgtcattat acttgaccga gttaagcact gtgtttggat cgcagataac
5281 caatccagca ctctcaactt tatccattca agccctcatg tcactctgtg gtaatgattt
5341 taattacctc ctgaatctaa tgggggccaa acactctgat ctgggtgcac tttatgaggc
5401 aaacttaatc aatggcagaa tcattcagta tgaccaagca agccaaatca tggttattca
5461 ggtctccgtg cccagcatat catcaatttc ggggttgcga ctgacagagt tgttcactct
5521 gagcattgaa acaccggtcg gcgagggcaa ggcagtagta ccccagtttg ttgtggaatc
5581 tggccagctt cttgaagaga ttgacaccca ggcatgcaca ctcactgaca ccactgctta
5641 ttgtactata gttagaacaa aaccattacc ggaactagtc gcacaatgcc tccgagggga
5701 tgagtctaga tgccaatata cgactggaat aggtatgctt gaatctcgat ttggggtgtt
5761 tgatggactt gttattgcta attgtaaggc caccatctgc cgatgtctag cccctgagat
5821 gataataact caaaacaagg gactccctct cacagtcata tcacaagaga cttgcaagag
5881 aatcctgata gatggagtta ctctacagat cgaagctcaa gttagtgggt cgtattccag
5941 gaatataaca gtcgggaaca gccaaattgc cccatccgga ccccttgaca tctcaagcga
6001 actcgggaag gtcaaccaaa gtctatctaa tgtcgaagat ctcattgacc agagcaatca
6061 gctcttaaat agggtgaatc caaacatagt aaacaacacc gcaatcatag tcacaatagt
6121 actgctagtc ctcttggtat tatggtgttt ggccctaacg attagtatcc tgtatgtatc
6181 aaaacacgct gtgcggatga taaagacagt tccgaatccg tatgtaatgc aagcaaagtc
6241 gccgggaagt gccacacagt tctaacaata tagctggtcc tgatgattaa accatatacc
6301 tgattacatg ataaaaatat gtcgagggat gacattgatg agacccctta ttctctctca
6361 aactaagaca gtaatccatc tagaatgcaa tgatcctact tcctttactt taatcaaaaa
6421 atgcagaata atctaacagc ccaaccaaac tacccagaaa gaaacgcctg aggggggaag
6481 gaggttgact gcaacctcaa ttgatcagag gttgtagtat taattctcca taaccctcaa
6541 gatgagacca caagtggcgg tttgggcttt gcgcttattg gccaccggcc tagctatgat
6601 ctccttagtg ttctgcctga accaggtaat tatgcaggtg ctaattaggg acattgggga
6661 cttgttgaca tcctcagaaa taaagactac acgtgagaca ctgcgtgagc atctctcatc
6721 tattactctt ttcatgtcgt ttgcgctgac ttgctcaata agtgggtgcg ttcttagcct
6781 ggttgcatta tatccaagca agaacattaa tggcactaac actcagccac aagtagagga
6841 ggccagatcg gagaacctgt ctcactcttc catgcacaca atcaataggc cagcgacccc
6901 tcccccaccg tattatgtag caatacaact cagcgctgag atgcaacctg ggtaccatcc
6961 aggtgattga tcctcctagc atgttggcag agtctacccc accaagatct gttcttgtac
7021 cacttttttg atttaagaaa aaattgtgat ttatataaaa acataatggc tgagggggaa
7081 gcctggtgtc accgctggtg accatttccc agccggtggc aatggcttcc tcaagcgata
7141 tgaggcagag tcaggcaact ttatatgagg gtgaccctaa tagcaaaagg acatggagga
7201 ccgtgtaccg ggttatcacc atattgttgg atataaccgt cctttgtgtc ggcatagtgg
7261 cagtagtcag gatgtcaacc attacgacaa aggatattga taacagtatt tcatcgtcca
7321 ttacttccct gagtgccgat taccagccaa tatggtcaga tacccatcag aaagtcaaca
7381 gtattttcaa ggaagtcgga atcactatcc ccgtcacact cgacaagatg caagtggaaa
7441 tgggaacagc agttaacata atcactgatg ctgtaaggca actacaagga gtcaatgggt
7501 cagcaggatt tagcattacc aattcaccag aatatagtgg agggatagac acactgatat
7561 accctcttaa ctcacttaat gggaaggctt tagccgtatc agacctactg gaacatccga
7621 gcttcatacc agcgcctacc acctctcatg gttgcacccg cattcctaca ttccacctag
7681 gataccgtca ttggtgttat agtcacaaca caatagaatc tggttgtcac gatgcagaag
7741 aaagcattat gtacgtatct atgggtgcgg taggggtcgg ccatcgtggg agacccgtgt
7801 ttacgacaag tgcagcaaca atcctagatg atggaaggaa caggaaaagt tgtagcatca
7861 tagcaaaccc taatgggtgt gatgtcttgt gcagcttggt taagcaaaca gagaacgagg
7921 actacgctga ccctacaccg accccaatga tccacggtag gctccacttc aatggcacgt
7981 acaccgagtc tgaactcaac cctggcctat ttaataatca ttgggtcgct caatatccag
8041 cagttggcag cggtgtcgtc agccacggga aactattctt tccgctttac ggagggatat
8101 caccgaagtc aaaactgttc aacgagctta agtcatttgc ttacttcacc cataatgccg
8161 aattgaaatg tgagaacctg acagagagac aaaaagaaga tctatataac gcatataggc
8221 ctgggaaaat agcaggatct ctctgggctc aaggggttgt aacatgtaat ctgaccaatc
8281 tagctgattg taaagttgca attgcgaaca cgagcaccat gatgatggct gccgagggga
8341 ggttacaact tgtgcaagat aggattgtct tctaccaaag atcctcatca tggtggccag
8401 tcctaatata ttatgatatc cctattagtg accttatcag tgccgatcat ttagggatag
8461 taaactggac tccatatcca caatctaaat ttccgaggcc cacctggaca aagggcgtat
8521 gcgagaaacc ggcaatatgt cccgctgtgt gtgtaacggg tgtttaccag gatatttggg
8581 tagtcagtat agggtcccag agcaatgaga ctgttgtggt tggcggatac ttagatgctg
8641 cagcagcccg tcaggatcca tggattgcag cagccaacca gtataactgg ctggttaggc
8701 gtcgcctttt tacatctcag actgaagcag catactcatc aaccacttgc ttcagaaaca
8761 cgaagcagga tagagtgttc tgcctgacta taatggaagt tacagacaac ctactcggag
8821 actggaggat cgccccgctg ttatatgagg ttactgtggc tgataagcaa cagggtaatc
8881 gcaattacgc gccaatgaga aggatgggga cggataagtt ccaatattat acaccaggtg
8941 ataaatatac tcctcagcat tgatgactca ctgcagcttg tacataacaa ttctcttgct
9001 tcctctattt gcagagtaaa tcagaagaat gacggtcggt gattgaccga acttaattag
9061 atggtgacat acagcccgca ttcatcttga tttaataaaa aactggggag ctgttataac
9121 atggcagact gacggggcaa gacccgcgga gacaaagaat gcagtgaggg ggaaggcagg
9181 ctgggatcac gtcccagctg tagccttccc cgattcaatc tacttagtat cgacaagtca
9241 attctgctca cagaggtcat ctgaaagggt tgttgtgatg gatccacaag tccaaataca
9301 ccacatcatc aagccagagt gccatctcaa ctcacctgtg gtggagaaga aactgacgct
9361 attatggaag ctcacaggtt taccgttgcc acctgacctt aatagttgcg ttacacacaa
9421 ggatgtgacg tgggatgaag tgctccggtt ggaggctaat ttgacaaagg aattacggca
9481 attggtgcga ggcctgacca atagaatgca tgaaagaggg gagtttattg actcatataa
9541 acctttatgc catccacgta cgttaagttg gttgactaat atcagcttga ttaagagtga
9601 caacattcta gcaggccata agaaaatgct agtccggatt ggcggtatgt tgcatgaaca
9661 aacagaccaa ttgtttgtca ctcttggcag gaaattagca ggtgaccctt gcttgttcca
9721 tcaactaggc cacctagctg gatgtccacc caattccaga tttgaggaac aggtaggagg
9781 ctgcagtttg tggtcaccca taagcgatcc agccctggtc acaggtggtg aatatgccaa
9841 ctgtgtgtat gcgtggtact taatacgtca aaccatgcgg tacatggccc tccagagaaa
9901 gcaaacaaga gtgcaatcac agcagaatgt cctaattgga tcagatacaa tcgtgggaat
9961 tcatccagaa ctagtgataa ttactggaat tagagacagg acattcacct gtttgacttt
10021 tgatatggtg ctaatgtacg cagatgtggt ggaaggccgt gccatgacaa agttggtcgc
10081 actcaccgag ccgacaatgg tagaagtcat tcagagagtc gaaaaattgt ggttcctagt
10141 tgacagcatc tttgaggaaa tcggtggtgc aggttacaat attgttgcat ctctggagag
10201 cttggcatat ggtgctgttc aactgtggga taaatcactg gaacatgctg gtgagttttt
10261 ctcattcaat cttactgaga taaggagtga gctagagaac catttagatc ctggtatggc
10321 atttagagta gttgagcagg tgcggttgct atatactgga ctgagtgtga accaagcagg
10381 tgaaatgtta tgcattttac gtcactgggg gcatcccttg ctgtgcgctg tgaaggcggc
10441 aaagaaagtc agagaatcga tgtgtgcacc gaaattaacc tctctagata ccacactcaa
10501 agtgttagca ttctttattg cagatattat caatggacat agacggtcac attcagggtt
10561 atggccaagt gtcagacaag agtcacttgt gtccccattg ctccagaacc tctatagaga
10621 atccgccgag cttcagtacg cgattgtgct taagcactat agagaagtat cccttattga
10681 attccaaaaa agtattgatt ttgacttagt tgaagatctg agcgtgttcc ttaaggataa
10741 agccatctgt cgaccaaaga gtaactggtt agctgtattc aggaagtccc tactccccgg
10801 acatttgaaa gataagctgc aatctgaggg cccttctaac cggcttctgc ttgatttttt
10861 gcaatcaagc gaatttgacc cggctaagga gttcgagtac gtgacatcac tggagtatct
10921 tcaggaccca gagttctgcg catcttattc cttaaaggaa agggaagtca agactgatgg
10981 gcgcatattt gcaaaaatga ctagaaaaat gaggaactgt caagtcttgc tagagagttt
11041 gctcgcatgc cacatatgcg attatttcaa agagaacgga gtagtacaag agcaaatcag
11101 cttaacgaaa tcactgcttg cgatgtcgca acttgctcct cgtgtgtctg agtatcaagg
11161 gagagttctc cgttcaactg ataggtgcag tagagctaca gctacacctg ggcaggacac
11221 aagcccaggc gagggggtca ggcgacggaa aacgattata gcatcattct tgactactga
11281 cctacagaaa tattgtctca attggaggta cactgtagta aaaccttttg cacagaggct
11341 taaccagtta tttgggatac cccacggctt tgagtggatt cacctccgct tgatgaatac
11401 gaccatgttt gtaggagacc cacataatgt ccctcagttt tcatcaacac atgacttaga
11461 atcccaagaa aatgatggaa tatttattgt atcacctcgg ggtggtatag aagggctatg
11521 ccaaaaaatg tggaccatga tctccattgc ggcaattcat ctagcagcca cagaatcagg
11581 ttgtcgggtt gcatctatgg tccaagggga caatcaagca attgcaatca ccacagagat
11641 cgaagagggt gaggacgcat ccgtagcatc aataaggtta aaagaaatat ctgagaggtt
11701 ttttagagtg ttcagagaga taaacagagg tatagggcac aacttaaaag tccaagaaac
11761 aattcatagt gagtcattct tcgtgtactc gaaacggatc ttctttgagg ggaagatcct
11821 cagtcaacta ctaaaaaatg caagtaggtt agtgttggta tccgagaccg tgggtgagaa
11881 ttgtgtcggc aattgctcaa atatcagttc cacagttgct aggctcattg aaaatggatt
11941 ggataagaga gtcgcatggg ggctcaatat catgatgatc gtaaaacaaa ttctttttga
12001 cattgatttc tccttggagc ctgaaccatc tcaaggcttg attcatgcta ttcgccaaga
12061 tccaaacaac ataaaaaaca tctctatcac tcctgctcaa ttgggtggat taaattttct
12121 agccctatct cggctattta caaggaacat aggagacccc gtctcgtcag ccatggcaga
12181 tatgaagttc tacatacagg tcggattatt atcccctcat ctgctaagga atgcaatttt
12241 tagggaaccc ggagatggaa cgtggacaac actgtgcgcc gacccgtact cattaaacca
12301 accatatgtg caattgccaa cgtcgtactt aaaaaagcac acacaacgca tgctgctcac
12361 tgcctcaaca aatcctttat tgcaaggcac ccgagtagag aatcagtaca ttgaggaaga
12421 aagactagca aagttccttc tggatcgaga actggttatg ccacgtgtgg cgcatacagt
12481 ctttgagacc actgttgccg ggagacgaaa gcatctgcaa ggattgattg acaccacacc
12541 gaccattatt aaatatgccc ttcatcacca ccctatttct ttcaagaaaa gcatgctgat
12601 atcatcttac tcagctgact acattatgtc gttcatcgat actatcgcaa cagtggaata
12661 cccaaagcgt gacaccatga agctctggaa cagaggacta ataggtgtcg acacctgcgc
12721 ggtcacactt gcggattacg caagaacata ttcgtggtgg gagatcctaa agggaaggtc
12781 gataaaggga gttaccacac ctgatacatt agaactttgc tctgggagct taatagagca
12841 aggccatccg tgtgctcagt gcacaatggg tgatgaatcc ttttcatggt tcttcctccc
12901 aggaaatatt gatattgaaa ggccagactt ttctagggtg gcccagagaa tcgcttatgt
12961 cggctcaaag acggaagaaa ggcgggcagc ttcactgaca acaatcaaag ggatgtcaac
13021 tcaccttagg gcggcattaa gaggagcgag tgtttacatc tgggcgtatg gagacagtga
13081 caagaattgg gacgatgcta ccaagctcgc taacacaaga tgtgtaatat ctgaagacca
13141 tctacgtgcc ctttgtccaa tcccaagttc agcaaacata cagcatagac tgatggatgg
13201 aataagtgta acgaagttca ctcccgcgtc tctagcaagg gtgtcatcat atattcatat
13261 ttcaaatgac cggcatcaga gtagaattga cggtcaagtg atcgaatcaa atgtgatttt
13321 ccaacaggtt atgcttctcg gtctcggcat ttttgagaca tttcaccctt tgtctcacag
13381 gtttgtgact aaccccatga cactccactt acacacaggg tactcatgtt gcataagaga
13441 agctgataat ggtgatttct tagaatcccc ggctagtgta ccagacatga ctatcacgac
13501 tggcaataag tttctttttg accccatgcc catccaggat gacgatgctg caaaactaca
13561 ggtatcttca ttcaagtact gtgagatggg ccttgaagtg cttgacccac caggacttgt
13621 aaccttacta tccctagtga ctgcacgcat ctctattgat acatccatag gggagagcgc
13681 gtacaactcg atacacaatg atgctattgt atcattcgac aattccatca actggatatc
13741 tgagtacacg tactgcgatc ttagactact ggcagtagca atggctcggg agttttgcga
13801 caatctctct tatcagcttt actatctgag agttaaaggg cgacgggcaa tccgggatta
13861 tatccgtcaa gccctctcga ggataccagg gttacagctc gctaatatag ccttgactat
13921 atctcatccg ggaatttggg caagactgag gctaatcggg gcagtaagtg ctgggaatag
13981 ccccattagt gcaaccgtaa attatcctgc tgctgtgtgt gagctcatac tatggggtta
14041 tgaccaatat actgcacaac tactagatgg ttatgaatta gaaatcatag tcccaaatta
14101 taaggatgat gacttgaaca ggaaagttga acatatatta gcaagacggg cttgtctgct
14161 gagtctactg tgtgagtatc caggaaaata cccgaacatc aaagaccttg aacctattga
14221 gaaatgcact gccctgtctg acctgaataa attgtggatg gcgacagatc acagaactcg
14281 ggaatgtttt tcagggatat ctcagatatt tgattcaccc aagttaaatc cattcatcac
14341 taatctttac ttcttgagta ggaagctgct caatgcaatt agaagcagca cggactgtag
14401 ggcctacgtt gaaaaccttt atgaagatat tgacattgaa ctaacatctc tcactgaggt
14461 tgtaccctta ggagaggatg atcaaatgat cactgggcct ctgcgctttg accttgaact
14521 aaaagaactc accccagatt ttactatcac ttggtgttgc tttgactcca cggcagcact
14581 gatgtcacgg tgcattaatc atgccacaga aggtgcagag cgctacatcc gaagaacggt
14641 cgggacagct tcaacatctt ggtacaaagc agcaggaata ttaactacac ctggcttcct
14701 caacctccct aaaggcaatg gattgtatct cgctgagtca tcaggggcca ttatgactgt
14761 gatggagcat cttgtctgct ctaataaaat ctggtataac accttgttta gcaatgagct
14821 caacccacct cagaggaatt tcggtcctaa cccaattcag tttgaagaaa gtattgtggg
14881 gaaacacatt gcagctggga ttccttgcaa ggcaggacac gtgcaagagt tcgaggtact
14941 ctggagagag gtagatgaag agacagatct gacatccatg agatgtgtga attttatcat
15001 gtcgaaagtt gaacagcact cgtgtcatat tgtatgctgt gatttagaat tggctatggg
15061 aactcccctg gaagtggccc aatctgcata tacacacatc ataaccctcg ccttacattg
15121 cctaatgatt agcggaaaat tagtactgaa gttgtatttc tcacaaaatg ccttattaca
15181 ccatgttctc tccttgttac ttgtattacc atttcatgta acaatccaca ctaatgggta
15241 ttgctctcac cgaggctctg aagggtatat catcgccacg aggacagggg ttgctctggg
15301 ttcaaatgtg tcccaggtac taggcagtgt gactgagatg gtacggaaag gtcagaccct
15361 tgtccccgta aaggtactta cagcgatctc caatggattt aaaactgtat caagctcttt
15421 aggcaggctt aggggtgagc tctattcgcc atcgtgtagc attccgcagt cggctacaga
15481 catgttcctc attcaacttg gagggaaggt gcagtcagat tggaatacaa actctcgagg
15541 ctatagagtg ggtgataccg aactcgtatt acaggacatt atatcaatat tgagcacact
15601 actaaaagaa ataatacatg taagggaatc cagggagtca gtggacaggg tgctgttgct
15661 tggggcatac aacctgcaag tatccggaaa agtaagaaca atggctgcgg ctgcaacaag
15721 aaacatattg catctccata tagttagact tattggggac tcaatgtcca atataaggag
15781 actagtacct ctgctagata agggctttat agtaatatca gacatgtata gtgtgaaaga
15841 tttcttgaga aaaactgagt cccctaagta cttcttgaac aagcttggca agagcgagat
15901 tgcacagata tttgaggtag agtccaagat tattctgagc agggcagaga tcaagaatat
15961 tttgaaaatg atagggattg tagcaaaaca gcactcagag taatctcttc aactttgcgc
16021 cgcttgaatc ctgaactgtg gacgcgcacg cttaagcgca ccagcctgac gtgacgattg
16081 atataatcct tggtatgaat caccaatcat ctggaactca cttacttccc gaaatcaccc
16141 atagaccggt atcggtatcg gagattatta tttaataaaa aacctggaaa gtcaacaagg
16201 atcatagtca aaaagcttat gatttccttg tttggt
//
