LOCUS NC_039231 13373 bp RNA linear VRL 24-AUG-2018
DEFINITION Avian pneumovirus strain LAH A, complete genome.
ACCESSION NC_039231
VERSION NC_039231.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Avian metapneumovirus
ORGANISM Avian metapneumovirus
Viruses; Riboviria; Orthornavirae; Negarnaviricota;
Haploviricotina; Monjiviricetes; Mononegavirales; Pneumoviridae;
Metapneumovirus; Metapneumovirus avis.
REFERENCE 1 (bases 1 to 13373)
AUTHORS Naylor,C.J., Brown,P.A., Edworthy,N., Ling,R., Jones,R.C.,
Savage,C.E. and Easton,A.J.
TITLE Development of a reverse-genetics system for Avian pneumovirus
demonstrates that the small hydrophobic (SH) and attachment (G)
genes are not essential for virus viability
JOURNAL J. Gen. Virol. 85 (PT 11), 3219-3227 (2004)
PUBMED 15483235
REFERENCE 2 (bases 1 to 13373)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (24-AUG-2018) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 13373)
AUTHORS Naylor,C.J. and Easton,A.J.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-2004) Biological Sciences, University of Warwick,
Gibbet Hill Road, Coventry, West Midlands CV4 7AL, UK
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to AY640317.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..13373
/organism="Avian metapneumovirus"
/mol_type="genomic RNA"
/strain="LAH A"
/db_xref="taxon:38525"
/country="United Kingdom"
gene 42..1240
/gene="N"
/locus_tag="D1Y46_gp1"
/db_xref="GeneID:37627240"
mRNA 42..1240
/gene="N"
/locus_tag="D1Y46_gp1"
/product="N"
/db_xref="GeneID:37627240"
CDS 56..1231
/gene="N"
/locus_tag="D1Y46_gp1"
/note="nucleoprotein"
/codon_start=1
/product="N"
/protein_id="YP_009513220.1"
/db_xref="GeneID:37627240"
/translation="MSLESIRLSDLEYKHAILEDSQYTIRRDVGATTAITPSELQPQV
STLCGMVLFAKHTDYEPAAEVGMQYISTALGADRTQQILKNSGSEVQGVMTKIVTLSA
EGSVRKREVLNIHDVGVGWADDVERTTREAMGAMVRDKVQLTKNQKPSALDAPVILLC
IGALIFTKLASTVEVGLETAIRRASRVLSDAISRYPRMDIPRIAKSFFELFEKKVYYR
NLFIEYGKALGSTSTGSRMESLFVNIFMQAYGAGQTMLRWGVIARSSNNIMLGHVSVQ
AELRQVSEVYDLVRKMGPESGLLHLRQSPKAGLLSLTNCPNFASVVLGNAAGLGIIGM
YKGRAPNLELFAAAESYARTLRENNKINLAALGLTDDEREAATSYLGGDDERSSKFE"
misc_feature 56..1210
/gene="N"
/locus_tag="D1Y46_gp1"
/note="Pneumovirus nucleocapsid protein; Region:
Pneumo_ncap; pfam03246"
/db_xref="CDD:397378"
gene 1244..2104
/gene="P"
/locus_tag="D1Y46_gp2"
/db_xref="GeneID:37627232"
mRNA 1244..2104
/gene="P"
/locus_tag="D1Y46_gp2"
/product="P"
/db_xref="GeneID:37627232"
CDS 1257..2093
/gene="P"
/locus_tag="D1Y46_gp2"
/note="phosphoprotein"
/codon_start=1
/product="P"
/protein_id="YP_009513221.1"
/db_xref="GeneID:37627232"
/translation="MSFPEGKDILMMGSEAAKMADAYQRSLRNTSAGGRSISGEPINT
IAEKVPLPPLCNPTTPKGSCIKPNKAPVPKVKEIESIYPKLPTAPVATDTETSTSTES
AEKSKKVKFDNPKVGKYTKLEEEALELLSDPEEDNDEKSSILTFEEKDTASTSIEARL
EAIEEKLSMILGMLKTLNIATAGPTAARDGIRDAMIGMREELINSIMTEAKDKIAEMM
KEEDTQRAKIGDGSVKLTEKAKELNKILEDQSSSGESESEEESGESESDEEESDIYNL
DL"
misc_feature 1266..2003
/gene="P"
/locus_tag="D1Y46_gp2"
/note="Pneumovirus phosphoprotein; Region:
Pneumo_phosprot; pfam02478"
/db_xref="CDD:280615"
gene 2106..2929
/gene="M"
/locus_tag="D1Y46_gp3"
/db_xref="GeneID:37627233"
mRNA 2106..2929
/gene="M"
/locus_tag="D1Y46_gp3"
/product="M"
/db_xref="GeneID:37627233"
CDS 2119..2883
/gene="M"
/locus_tag="D1Y46_gp3"
/note="matrix protein"
/codon_start=1
/product="M"
/protein_id="YP_009513222.1"
/db_xref="GeneID:37627233"
/translation="MESYIIDTYQGVPYTAAVQVDLIEKDSNPATLTVWFPLFQSSTP
APVLLDQLKTLSITTQYTASPEGPVLQVNAAAQGAAMSALPKKFAVSAAVALDEYSRL
EFGTLTVCDVRSIYLTTLKPYGMVSKIMTDVRSVGRKTHDLIALCDFIDIEKGVPITI
PAYIKAVSIKNSESATVEAAISGEADQAITQARIAPYAGLILIMTMNNPKGIFKKLGA
GMQVIVELGPYVQAESLGKICKTWNHQRTRYVLRSR"
misc_feature 2119..2874
/gene="M"
/locus_tag="D1Y46_gp3"
/note="Pneumovirus matrix protein; Region: Pneumo_matrix;
pfam03393"
/db_xref="CDD:308800"
gene 2932..4571
/gene="F"
/locus_tag="D1Y46_gp4"
/db_xref="GeneID:37627234"
mRNA 2932..4571
/gene="F"
/locus_tag="D1Y46_gp4"
/product="F"
/db_xref="GeneID:37627234"
CDS 2944..4560
/gene="F"
/locus_tag="D1Y46_gp4"
/note="fusion protein"
/codon_start=1
/product="F"
/protein_id="YP_009513223.1"
/db_xref="GeneID:37627234"
/translation="MDVRICLLLFLISNPSSCIQETYNEESCSTVTRGYKSVLRTGWY
TNVFNLEIGNVENITCNDGPSLIDTELVLTKNALRELKTVSADQVAKESRLSSPRRRR
FVLGAIALGVATAAAVTAGVALAKTIRLEGEVKAIKNALRNTNEAVSTLGNGVRVLAT
AVNDLKEFISKKLTPAINQNKCNIADIKMAISFGQNNRRFLNVVRQFSDSAGITSAVS
LDLMTDDELVRAINRMPTSSGQISLMLNNRAMVRRKGFGILIGVYDGTVVYMVQLPIF
GVIETPCWRVVAAPLCRKRRGNYACILREDQGWYCTNAGSTAYYPNKDDCEVRDDYVF
CDTAAGINVALEVDQCNYNISTSKYPCKVSTGRHPVSMVALTPLGGLVSCYESVSCSI
GSNKVGIIKQLGKGCTHIPNNEADTITIDNTVYQLSKVVGEQRTIKGAPVVNNFNPIL
FPVDQFNVALDQVFESIDRSQDLIDKSNDLLGADAKSKAGIAIAIVVLVILGIFFLLA
VIYYCSRVRKTKPKHDYPATTGHSSMAYVS"
misc_feature 3016..4428
/gene="F"
/locus_tag="D1Y46_gp4"
/note="Fusion glycoprotein F0; Region: Fusion_gly;
pfam00523"
/db_xref="CDD:395418"
gene 4574..5360
/gene="M2"
/locus_tag="D1Y46_gp5"
/db_xref="GeneID:37627235"
mRNA 4574..5360
/gene="M2"
/locus_tag="D1Y46_gp5"
/product="M2-1"
/db_xref="GeneID:37627235"
CDS 4587..5147
/gene="M2"
/locus_tag="D1Y46_gp5"
/codon_start=1
/product="M2-1"
/protein_id="YP_009513224.1"
/db_xref="GeneID:37627235"
/translation="MSRRNPCRYEIRGKCNRGSSCTFNHNYWSWPDHVLLVRANYMLN
QLLRNTDRTDGLSLISGAGREDRTQDFVLGSANVVQNYIEGNTTITKSAACYSLYNII
KQLQENDVKTSRDSMLEDPKHVALHNLILSYVDMSKNPASLINSLKRLPREKLKKLAK
IILQLSAGPESDNASGNTLQKGDSNN"
misc_feature 4593..4661
/gene="M2"
/locus_tag="D1Y46_gp5"
/note="Zinc finger C-x8-C-x5-C-x3-H type (and similar);
Region: zf-CCCH; pfam00642"
/db_xref="CDD:425793"
misc_feature 4671..5111
/gene="M2"
/locus_tag="D1Y46_gp5"
/note="Pneumovirus matrix protein 2 (M2); Region:
Pneumovirus_M2; pfam06436"
/db_xref="CDD:399442"
gene 5104..5325
/gene="M2"
/locus_tag="D1Y46_gp6"
/note="copy 2"
/db_xref="GeneID:37627236"
CDS 5104..5325
/gene="M2"
/locus_tag="D1Y46_gp6"
/codon_start=1
/product="M2-2"
/protein_id="YP_009513225.1"
/db_xref="GeneID:37627236"
/translation="MPVVIPCRRVTAIIKCNALGLCMVRKIYDYSIASWSDLIEEVAN
MVLIDHINRKQCVECRKDLEFIAIYTSYN"
gene 5365..5962
/gene="SH"
/locus_tag="D1Y46_gp7"
/db_xref="GeneID:37627237"
mRNA 5365..5962
/gene="SH"
/locus_tag="D1Y46_gp7"
/product="SH"
/db_xref="GeneID:37627237"
CDS 5378..5902
/gene="SH"
/locus_tag="D1Y46_gp7"
/note="small hydrophobic protein"
/codon_start=1
/product="SH"
/protein_id="YP_009513226.1"
/db_xref="GeneID:37627237"
/translation="MTSTVNLGSDTASKWTVIKSRCNSCCRILVSCAAVICAILALIF
LVATIGLSVKLAFTVQEVHNCKQKLSGASTTTAAIYTTPSTMIEALQTNQLKLTTNER
RSTPPDCLVEKKLCEGEVRYLKTKGCLGAREGEDLNCIDLVVECVGKPCGHNEDYKEC
ICTNNGTATKCCYN"
gene 5967..7194
/gene="G"
/locus_tag="D1Y46_gp8"
/db_xref="GeneID:37627238"
mRNA 5967..7194
/gene="G"
/locus_tag="D1Y46_gp8"
/product="G"
/db_xref="GeneID:37627238"
CDS 5982..7157
/gene="G"
/locus_tag="D1Y46_gp8"
/note="attachment protein"
/codon_start=1
/product="G"
/protein_id="YP_009513227.1"
/db_xref="GeneID:37627238"
/translation="MGSKLYMVQGTSAYQTAVGFWLDIGRRYILAIVLSAFGLTCTVT
IALTVSVIVEQSVLEECRNYNGGDRDWWSTTQEQPTTAPSATPAGNYGGLQTARTRKS
ESCLHVQISYGDMYSRSDTVLGGFDCMGLLVLCKSGPICQRDNQVDPTALCHCRVDLS
SVDCCKVNKISTNSSTTSEPQKTNPAWPSQDNTDSDPNPQGITTSTATLLSTSLGLML
TSKTGTHKSGPPQALPGSNTNGKTTTDRELGSTNQPNSTTNGQHNKHTQRMTLPPSYD
NTRTILQHTTPWEKTFSTYKPTHSPTNESDQSLPTTQNSINCEHFDPQGKEKICYRVG
SYNSNITKQCRIDVPLCSTYNTVCMKTYYTEPFYCWRRIWRCLCDDGVGLVEWCCTS"
misc_feature 5982..7154
/gene="G"
/locus_tag="D1Y46_gp8"
/note="Pneumovirinae attachment membrane glycoprotein G;
Region: Pneumo_att_G; pfam05539"
/db_xref="CDD:114270"
gene 7235..13333
/gene="L"
/locus_tag="D1Y46_gp9"
/db_xref="GeneID:37627239"
mRNA 7235..13333
/gene="L"
/locus_tag="D1Y46_gp9"
/product="L"
/db_xref="GeneID:37627239"
CDS 7244..13258
/gene="L"
/locus_tag="D1Y46_gp9"
/note="large polymerase subunit"
/codon_start=1
/product="L"
/protein_id="YP_009513228.1"
/db_xref="GeneID:37627239"
/translation="MEISDESVVNVYLPDSYLKGVISFSETNAIGSCVLNRPYIKDDY
TAHVAMTNPVIEHQRLRALFKSLTISREYRVVEPLMIQKELLKVAAGARLKKLKKWLG
RSKDISEVKLKMVTDWLKLSQTPGRGKIIDRIQVENLPDWLEHWFDSWLILNDVIQSY
RCLEVSQTSAILRKSSLNFFFAVSSFGCIIISRKSRRICFCTYNQLLTWKDLALSRFN
ANLCVWVSNCLNSAQDGLGLRSKLVGELLNRLYCETDELLSITGNEGYGIVKEFEGFI
MSEILRMTEHAQFSVRFRNTLLNGIADKIGKMRAAYRRRTQNTSVEHHRYPGEHEMLE
ATGRVLRIIKLLVNNEIANAAEMYFIFRIFGHPMVEEREAMDAVRDNSETAKILSLVA
LTEMRGAFILRVIKGFVGNYKRWPKIKNPSTLSRRWKMYMNAKTYPSNLELCVEDFLE
LAGISFCQEFYVPSQTSLEMVLNDKAISPPKSLIWSVYPRNYLPQNIQDRFRLESLDR
LEHERTRRVLEFYLKDANFKQSDLKKYVVGQEYLNDKEHVVSLTGKERELSVGRMFAM
QPGKQRQVQILAEKLLSDNIVPFFPETLTRYGDLELQRIMELKSELSSTKKRKSDSYN
NYIARASIVTDLSKFNQAFRYETTSVCADVADELHGTQSLFCWLHLTVSSTTMICTYR
HAPPDTGGIYDIDQIPEQSGLYRFHMGGIEGWCQKMWTMEAISLLDVVSVRNRVQLTS
LLNGDNQSIDVSKPVRLTGAQTEIQADYSLAIKMLTAVRDAYYNIGHKLKEGETYVSR
DLQFMSKTIQSEGVMYPAAIKKVLRVGPWINTILDDIKTSMEAIGSLCQELEFRGESF
VTSLIVRNFWLYIQCFVEAKDHSLAGAQISNELNRTLTKVKRFFRLADESSTVNLFMN
IPMQLGGGDPVVVYRSFYRRTPDFLTEVLTHMELLLTAIEMDRGVYMNFFLTLLNTCK
NDRATLTTLMRDPQAIGSERQAKVTSEINRTAVTSVLSLAPNPLFSDSAVHFSQNEEE
IGTVMEDISPVYPHGLRVVYEAFPFHKAEKVVNMIAGTKSITNILQRTSAISGVDIDR
AVHMMLLNLGLLGRILESGPITDTIDLRSNNRILCCQLSKRIREMSWDGLEIVGVSSP
SMLSSLDINYVTIAQKPGIIVEKFSAEKTTRGKRGPKAPWVGSSTQEKKLVAVYNRQA
LSKEQKDQLETIGKIRWVYKGVTGLRRLLNLICLGTLGLPYKLLKPLLPRFMSVNFLH
RLAVSSRPMEFPSSVPAYRTTNFHFDTSPINKRLSERFGNEDINLVFQNAISCGISVM
CVVEQLTGRSPKQVLLEPIVEDIDIMSAPNFQGHLNFKSVRKIVTDQHIFNPDHIDLV
MLGKLLLPTVRSNINNNKPATENFFNGNNIVEALTSCLACHWCTVLILLTTENSIFQK
EWGDGFITDHAFINFTWFLMSFKTYLLCHWQTEKNKTLGIVEDPIDRLIRVDNSFWRM
MSKVFLEPKVKRRLMLYDTSVLNVLGSISFKNWFVSRLRTVDYMEIPWIVNAEGDIVE
QKPVTEYLKIMAAGVHVKVIMLSYSDMAHAMTRLLRCKNMQDNVPTIKKTVSPTDVTP
SVDPTRALLLFPKVIFSKLTTFNATCSTAKQSGSNLTKNYMTLMPWHHINRYNFVHSS
TGCKVSVKGCIGKLITKLELRIIYFIGEGAGNLMSRTACEYPNLKFVYRSLKDANDHH
HPTEYVRVMGSISRIIDLGEGLAMEATDATKREHWDFIHRVCKDPLLLTICDAELKNM
EDVLHLVIQWRKHVLSCNICTSYGTNVYMFVKYHAQSEAKKLPHFVRVVSIYIMQGSK
LSGSECYMLLTLGHQNMAPCYGEVRSAKSIMALTSTFKHPCRLDKSAIEANLKSLAPG
LTLPLSEPAMQKYLLDLSSLSGIKNTGATIGGSKVVEKKWALCKVSNIVKWLSHVLKM
PKGDLNYDFFEVIENTYPDMVKLLDNLNPSELKKLVKVTGYILGTK"
misc_feature 7286..10522
/gene="L"
/locus_tag="D1Y46_gp9"
/note="Mononegavirales RNA dependent RNA polymerase;
Region: Mononeg_RNA_pol; pfam00946"
/db_xref="CDD:395756"
misc_feature 10868..13249
/gene="L"
/locus_tag="D1Y46_gp9"
/note="mRNA capping enzyme, paramyxovirus family; Region:
paramyx_RNAcap; TIGR04198"
/db_xref="CDD:275046"
ORIGIN
1 acgagaaaaa aacgcattca agcaggttct agaaaaataa tgggacaagt caaaaatgtc
61 tcttgaaagt attagactca gtgacttgga gtacaaacat gcaattcttg aagactctca
121 gtatacaatt agaagggatg ttggtgctac cactgcgatc acaccttccg aactgcagcc
181 gcaagtatcc acattatgcg gtatggtgtt gtttgcaaaa cacaccgact atgagcctgc
241 agcagaggta ggcatgcagt acattagtac tgctctagga gctgatagaa ctcaacaaat
301 actgaaaaat tccggtagtg aagtacaggg tgttatgacc aagattgtaa cactttcggc
361 agagggttct gtcagaaagc gagaggtgct aaacattcac gatgtgggtg ttgggtgggc
421 tgatgatgtc gaaaggacta caagagaagc aatgggagca atggttaggg ataaagtgca
481 actcacaaag aatcaaaagc cgtctgcctt ggatgctccc gttattctat tatgcattgg
541 tgccctcatt ttcaccaagt tggcctcaac tgttgaagta ggccttgaaa ctgctatccg
601 gcgtgcctca agggtattaa gcgatgccat atcacggtac cccaggatgg acataccaag
661 gattgccaaa tcattctttg aattgtttga gaagaaggtg tattacagaa atctatttat
721 tgaatacggt aaggcactcg gaagtacatc caccggaagc aggatggaga gcctgtttgt
781 gaatattttt atgcaagctt atggggcagg gcaaacaatg ctgcgctggg gtgtcattgc
841 acgatcctcc aacaatataa tgttgggcca tgtatctgtc caagctgagt tgaggcaagt
901 atctgaggtc tatgacctag tgaggaaaat gggacctgag tcagggttac tacacttacg
961 ccagagtccc aaagcgggtc ttttatcatt gaccaactgt cccaattttg ccagtgttgt
1021 cctcgggaac gccgccgggc ttggtattat aggcatgtac aaaggtcgag cccccaacct
1081 tgagctgttt gctgctgctg aaagttatgc acggacattg agagagaaca acaagatcaa
1141 cctagcggcc ttagggctca ctgatgatga gagggaagca gcaacatcct acctaggggg
1201 agatgatgag agatcatcca aatttgagta attaaaaaaa tatgggacaa gtaacaatgt
1261 ctttccctga aggcaaggat attctaatga tgggcagcga ggctgcaaaa atggccgatg
1321 cctatcaaag atcactaagg aacacctctg ctggaggtcg ttctattagt ggggagccta
1381 ttaacacaat tgctgaaaag gtgccattac cccctttgtg caaccccacc acaccaaagg
1441 gatcatgtat aaaacctaac aaagctcctg tccccaaggt caaagaaata gaatctatat
1501 atccaaaact cccgactgct ccagttgcca ctgacactga gacttctacc agtactgagt
1561 ctgcagaaaa gtctaaaaag gtcaagtttg acaaccccaa agtaggaaaa tatactaaac
1621 tggaagaaga ggcactagag ctgttgtcag atcctgaaga agataatgat gaaaagtcat
1681 caatattgac atttgaagaa aaagatacag catctacctc tattgaagca agattagaag
1741 caatagaaga aaagttgagc atgatattgg gcatgctcaa aacattgaat attgcaactg
1801 ctggcccaac cgccgccaga gatgggatac gtgatgcaat gatagggatg agagaagagc
1861 tgatcaacag catcatgaca gaggctaaag acaaaattgc agaaatgatg aaagaagagg
1921 acacccagag ggcaaaaata ggagatggta gcgtgaagct taccgaaaaa gccaaagagt
1981 tgaacaaaat cctagaagac cagagctcaa gtggagagtc agagagtgaa gaagagagtg
2041 gagagtctga atctgatgag gaagagagcg acatatacaa tcttgatctg tagttatgaa
2101 aaaatgggac aagtcaaaat ggagtcctat ataattgaca cttatcaggg ggttccctac
2161 actgcagccg ttcaggttga cctcattgaa aaagactcta accctgcaac actgactgta
2221 tggtttcccc tattccagtc aagtacgcct gccccagtgt tattagatca actgaaaact
2281 ttatcaatca ccacccagta cacagcatcc ccggaaggcc ctgtgctcca agtcaatgca
2341 gcagcccaag gtgccgccat gtctgcacta cctaagaaat ttgccgtcag tgctgcagta
2401 gcacttgacg agtacagtag gttggaattc gggacattga ctgtgtgtga tgtgaggtcc
2461 atttatctga ctaccttgaa gccatatggc atggtctcca aaataatgac agatgtgagg
2521 tctgttggga ggaagactca tgacttgatc gcattgtgtg attttataga catagagaaa
2581 ggggtgccca taaccatacc tgcatatatt aaagctgtct ctatcaagaa ctcagaatca
2641 gccactgtgg aagctgcaat aagtggggaa gcagaccagg ctataactca agcaaggata
2701 gctccatatg cagggctgat cttgattatg accatgaaca accctaaagg gatctttaag
2761 aaattgggtg caggtatgca agttatagta gaactggggc cgtatgtaca agcagagagt
2821 ctgggaaaaa tctgcaagac atggaatcat caacgaacca ggtatgtact gaggtcacgt
2881 tgagggtacc ctaaagcata gatctgttaa tgttatagtc aataaaaaat tgggacaagt
2941 aggatggatg taagaatctg tctcctattg ttccttatat ctaatcctag tagctgcata
3001 caagaaacat acaatgaaga atcctgcagt actgtaacta ggggttataa gagtgtgtta
3061 aggacagggt ggtatacgaa tgtatttaac ctcgaaatag ggaatgttga gaacatcact
3121 tgcaatgatg gacccagcct aattgacact gagttagtac tcacaaagaa tgctttgagg
3181 gagctcaaaa cagtgtcagc tgatcaagtg gctaaggaaa gcagactatc ctcacccagg
3241 agacgtagat ttgtactggg tgcaattgca cttggtgttg cgacagctgc tgccgtaaca
3301 gctggtgtag cacttgcaaa gacaattaga ttagagggag aggtgaaggc aattaagaat
3361 gccctccgga acacaaatga ggcagtatcc acattaggga atggtgtgag ggtactagca
3421 actgcagtca atgacctcaa agaatttata agtaaaaaat tgactcctgc tattaaccag
3481 aacaaatgca atatagcaga tataaagatg gcaattagtt ttggccaaaa taacagaagg
3541 ttcctgaatg tggtgaggca attctctgat agtgcaggta tcacatcagc tgtgtctctt
3601 gatttaatga cagatgatga acttgttaga gcaattaaca gaatgccaac ttcatcagga
3661 cagattagtt tgatgttgaa caatcgtgcc atggttagaa ggaaggggtt tggtatattg
3721 attggtgttt atgatggaac ggtcgtttat atggtacaac tgcccatatt cggcgtgatt
3781 gagacacctt gttggagggt ggtggcagca ccactctgta ggaaacgccg cggcaattat
3841 gcttgtatac tgagagaaga tcaagggtgg tactgtacaa atgctggctc tacagcttat
3901 tatcctaata aagatgattg tgaggtaagg gatgattatg tattttgtga cacagcagct
3961 ggcattaatg tggccctaga agttgaccag tgcaactata acatatcgac ttctaaatac
4021 ccatgcaaag tcagcacagg tagacaccct gtcagtatgg tagccttaac ccccctaggg
4081 ggtctagtgt cttgttatga gagtgtaagt tgctccatag gtagcaataa agtagggata
4141 ataaaacagc taggcaaagg gtgcacccac attcccaaca acgaagctga cacgataacc
4201 attgataaca ctgtgtacca attgagcaag gttgtaggcg aacagaggac cataaaagga
4261 gctccagttg tgaacaattt taacccaata ttattccctg tggatcagtt caatgttgca
4321 cttgaccaag tatttgagag tatagataga tctcaggact taatagataa gtctaacgac
4381 ttgctaggtg cagatgccaa gagcaaggct ggaattgcta tagcaatagt agtgctagtc
4441 attctaggaa tcttcttttt acttgcagtg atatattact gttccagagt ccggaagacc
4501 aaaccaaagc atgattaccc ggccacgaca ggtcatagca gcatggctta tgtcagttaa
4561 gttatttaaa attgggacaa gtgaagatgt ctaggcgaaa tccctgcaga tatgaaatac
4621 ggggcaaatg caacagggga tcatcctgta catttaacca taattattgg tcctggcctg
4681 atcatgtgct cttagtcaga gcaaactaca tgcttaacca attattgaga aacacagaca
4741 ggacagatgg cctatccttg atatcagggg caggacgaga agatagaacc caggattttg
4801 ttctaggatc tgccaatgtt gtacagaatt atatagaagg gaacacaaca atcaccaaat
4861 cagcagcctg ctacagcctg tacaacatta taaaacagct ccaggaaaat gatgtgaaaa
4921 catccagaga ttcaatgctt gaagacccta aacatgtggc gctacacaat ctgatactat
4981 cttatgttga tatgagtaaa aatccggcaa gtttgatcaa cagcctcaag cggcttccca
5041 gagaaaaact caaaaagctt gccaagatca tactacagct atctgcaggg ccagagagtg
5101 acaatgccag tggtaatacc ctgcagaagg gtgacagcaa taattaagtg caatgcactt
5161 ggattgtgta tggttcgtaa gatatatgat tatagtattg cgagctggag tgatttaata
5221 gaggaagtag ccaatatggt cctaatagat cacatcaata ggaaacaatg tgtggagtgt
5281 cgaaaagatc ttgagtttat agctatatat acctcatata attagttaat taaaaccaat
5341 taagctataa gtccaaaaaa gggtgggaca agtcataatg acttctaccg tcaaccttgg
5401 gtcagacact gcttcaaaat ggacagtgat caagtcaagg tgcaattctt gctgcaggat
5461 cttggtgagt tgtgctgctg tgatttgtgc aatcttagct ttgatcttcc ttgttgctac
5521 gatcggattg tctgtgaaac tggcattcac agtgcaggag gtccacaact gcaagcagaa
5581 gttatcagga gcgagcacaa ctacagctgc aatctatact accccaagta caatgataga
5641 ggcactacag acaaatcaac ttaaactgac aaccaatgaa agacgtagta ctccccctga
5701 ctgcctggta gagaaaaaat tgtgcgaagg tgaggtcagg tatctcaaaa ctaaaggctg
5761 cttgggagca cgagagggtg aagatttgaa ttgtatagat ttagtggtgg agtgtgttgg
5821 gaaaccctgt ggtcacaacg aggattacaa ggaatgcata tgcaccaaca atgggacagc
5881 aactaagtgc tgctacaact aatgaatttt gacaacacta gtgccaaata ataggcaaca
5941 gtattattta tttacaaaga aaggtcggga caagtatctc aatggggtcc aaactatata
6001 tggttcaggg caccagtgca tatcaaactg cagtggggtt ctggctggac atcgggagga
6061 ggtacatatt ggctatagtc ctatcagctt tcgggctgac ctgcacagtc actattgcac
6121 tcactgttag cgtcatagtt gaacagtcag tgttagagga gtgcagaaac tacaatggag
6181 gagatagaga ttggtggtca accacccagg agcagccaac tactgcacca agtgcgactc
6241 cagcaggaaa ttatggagga ttacaaacgg ctcgaacaag aaagtctgaa agctgtttgc
6301 atgtgcaaat ttcttatggt gatatgtata gccgcagtga tactgtactg ggtggttttg
6361 attgtatggg cttattggtt ctttgcaaat caggaccaat ttgtcagcga gataatcaag
6421 ttgacccaac agccctctgc cactgcaggg tagatctttc aagtgtggac tgctgcaagg
6481 tgaacaagat tagcactaac agcagcacca cctctgagcc ccagaagacc aacccggcat
6541 ggcctagcca agacaacaca gactccgatc caaatcctca aggcataacc accagcacag
6601 ccactctgct ctcaacaagc ctgggcctca tgctcacatc gaagactggg acacacaaat
6661 cagggccccc ccaagccttg ccggggagca acaccaacgg aaaaacaacc acagaccgag
6721 aactagggtc cacaaaccaa ccaaattcaa ccactaatgg gcaacataat aaacacaccc
6781 aacgaatgac actcccgcca agttacgaca acacaagaac tatcctccag cacacaacac
6841 cctgggaaaa gacattcagt acatacaagc ccacacactc tccgaccaac gaatcagatc
6901 aatccctccc cacaactcaa aacagcatca actgtgaaca ttttgacccc caaggcaagg
6961 aaaaaatctg ctacagagta ggttcttaca actccaatat tacaaagcaa tgcagaattg
7021 atgtgccttt gtgttccact tataacacag tgtgcatgaa aacatactat accgaaccat
7081 tctactgttg gaggcgtatc tggcgttgct tgtgtgatga cggagttggt ctggttgagt
7141 ggtgttgcac tagttaacta aaaatgaaca catatatatc tgataataaa aaaacacatc
7201 agatagtcta aaacaattaa aagaatgaaa aacaaggacc aatatggaaa tatccgatga
7261 gtccgtcgta aatgtctatc tgcctgactc ttacttaaag ggggtcattt cattcagtga
7321 gaccaatgca attggatcat gtgtactcaa ccggccatac attaaggatg actatacagc
7381 acatgttgca atgactaatc cagtgattga acaccagagg ttgagggccc tcttcaagag
7441 tcttaccatt agcagagaat atcgagtggt cgaacctctt atgatccaga aggagctgct
7501 aaaagttgca gcaggtgcaa gactaaagaa actcaagaaa tggttgggta gaagcaagga
7561 tataagtgaa gtcaaattga aaatggtgac tgattggctt aaactgtcac agacaccagg
7621 aaggggaaaa ataatagatc gtattcaagt ggagaactta cctgactggc tggagcactg
7681 gtttgattct tggttgatat tgaatgacgt catccagtct tataggtgtt tggaagtatc
7741 ccaaaccagt gctatattac ggaaaagtag cctgaacttc ttttttgctg tttcttcttt
7801 cgggtgtata atcataagtc gcaagagtag aagaatatgt ttttgtacct acaatcaact
7861 cctgacttgg aaggaccttg ccttgagcag atttaatgca aacttgtgtg tgtgggtgag
7921 caattgctta aatagtgccc aagacggcct tggattaagg agcaaattag ttggtgagtt
7981 actcaaccga ttgtactgtg agactgatga gttattgagc atcactggca atgaggggta
8041 tgggattgta aaggaatttg aaggattcat tatgagcgaa atattgcgga tgactgaaca
8101 tgcacaattc agtgtaaggt tccggaatac gctattgaat ggcatagctg ataaaatagg
8161 gaagatgaga gctgcatacc gaaggcggac acagaacaca tctgttgagc atcatagata
8221 cccaggcgag catgaaatgc tggaagcaac agggagagtg ctgagaataa ttaagcttct
8281 ggtgaataat gagattgcta atgctgcaga gatgtatttt atattccgca tattcggaca
8341 tcctatggta gaagaaaggg aggctatgga tgcagtgagg gataacagtg aaactgcaaa
8401 aatcttaagt ctggtggccc ttacggagat gaggggggcc ttcattctga gagtgatcaa
8461 aggtttcgta gggaactaca aaagatggcc aaagataaag aatccatcaa cattgagtcg
8521 aaggtggaag atgtacatga atgcaaaaac atacccaagc aatcttgaat tgtgtgtgga
8581 agacttcttg gagctcgctg ggatcagttt ttgccaagaa ttctatgtac ctagccagac
8641 cagtttggag atggtactga atgataaagc aatatctcct cccaaatctc tcatatggtc
8701 cgtgtatcca cgtaactacc ttccgcaaaa catacaagac agattcaggt tggagtctct
8761 tgacagacta gagcatgagc gcaccaggag ggtgctagag ttctacttaa aagatgctaa
8821 ttttaagcaa agtgatctca aaaaatatgt tgtaggtcaa gagtacttga atgacaaaga
8881 gcatgtggtc tccttaacag gaaaagaaag ggaactaagt gtaggtcgta tgtttgcaat
8941 gcaacctgga aagcaaagac aggtgcagat ccttgctgag aaattgttat cagataacat
9001 agtgccattt ttcccagaga cattgactag gtatggagat ctagaattac aaagaatcat
9061 ggaactcaag tccgaactat cgtctacaaa aaaacggaaa agtgatagct acaataatta
9121 tatagcaaga gcttcaatag tgactgattt gagcaagttt aaccaagcct ttagatacga
9181 gactacttca gtgtgtgctg atgttgcaga cgaactgcat gggactcaaa gccttttctg
9241 ctggttacat ctgactgtat cctccacaac catgatctgc acttatagac atgctccccc
9301 tgacacaggt ggaatctacg acatagacca gataccggag caaagtggac tgtataggtt
9361 ccacatgggt ggcatagaag gctggtgcca aaagatgtgg accatggaag caatatcact
9421 ccttgatgtg gtgtctgtga ggaatcgggt gcagctcaca tcactgctga atggggacaa
9481 ccagtctata gatgtgagta aacctgtgcg actcacaggt gctcaaactg aaatacaggc
9541 tgattatagc cttgccatca agatgttaac tgctgtaagg gatgcctact ataacatagg
9601 acacaagttg aaggaagggg agacttatgt ttcaagagac ctccagttta tgagcaagac
9661 cattcaatca gaaggcgtaa tgtatcctgc tgcaattaag aaggttctgc gagtgggtcc
9721 ctggataaac acaatactgg atgacatcaa gactagtatg gaagctattg gaagtctctg
9781 tcaagagtta gaatttcgag gggagtcatt tgtgactagt cttatagttc ggaatttctg
9841 gttgtacatc cagtgctttg tcgaggcaaa agatcatagc ttagcaggtg cacaaatatc
9901 caatgagctt aatagaactt taaccaaagt taagagattc ttcaggttag cagatgagag
9961 cagcactgtt aacttgttca tgaacatacc aatgcagttg gggggagggg accctgttgt
10021 tgtttatagg agtttttata gacggacacc agattttttg acagaggtgt taacacacat
10081 ggagttacta ctaacagcaa tagagatgga tagaggagtt tatatgaact tcttcttaac
10141 actgttgaac acatgcaaaa atgatagagc cactcttacc acactgatga gagaccctca
10201 agctattggg tcagaaaggc aggctaaggt aacaagcgaa attaatagaa cagcagtaac
10261 tagtgtgctc agccttgcac caaacccctt gttcagtgat agtgctgtgc atttcagtca
10321 gaatgaggaa gaaataggca cagttatgga ggatatatca cctgtctacc cacatggact
10381 gagagtggtg tatgaagcat tcccattcca caaagctgaa aaagttgtaa acatgattgc
10441 cggaaccaaa tccataacaa atatcctcca aagaacttct gctataagtg gtgtagatat
10501 tgacagagca gtccacatga tgttgctcaa cttgggcctg ttgggtagaa tacttgagtc
10561 tggacctatc actgacacaa tagatctgag gagcaacaat cggattcttt gttgtcagct
10621 ttccaaaaga ataagagaaa tgtcatggga tgggttggag attgtcggtg tatcatctcc
10681 aagcatgttg tctagcttag atattaatta tgttacaata gcacagaagc caggtatcat
10741 tgtagaaaaa ttctcagctg aaaaaacaac aagagggaaa agaggtccga aagcaccatg
10801 ggtaggttca agcacacaag agaaaaaatt ggtagctgtt tacaacagac aggccttatc
10861 gaaagaacaa aaagaccaat tagaaaccat aggcaaaatc aggtgggtct acaaaggcgt
10921 tactggcctc cgacgtcttc taaacttaat atgcttagga acactgggtc ttccatataa
10981 gctgttaaaa ccacttctac ctcggtttat gagcgtcaat ttcctacaca ggcttgcagt
11041 gagcagcagg cctatggagt tcccatcatc agtaccggcg tatagaacta caaactttca
11101 ttttgacact agtcctataa acaagcggtt gagtgagaga tttggcaatg aggacattaa
11161 ccttgtgttc caaaatgcta taagttgtgg aattagtgtc atgtgtgtgg ttgaacaatt
11221 gactgggcgt agccctaaac aagtgttact agaacctatc gtagaagata ttgacataat
11281 gtccgcccct aatttccagg gccacctgaa tttcaagagt gtaagaaaga ttgtgactga
11341 tcaacatatc tttaatccgg accacatcga cttggttatg cttgggaagt tgttattacc
11401 aactgtccgt agcaatataa ataacaacaa accagcaact gaaaacttct ttaatggtaa
11461 caacatagta gaggcactaa caagctgtct tgcttgccac tggtgcactg ttttgattct
11521 actcactact gagaatagta ttttccagaa agagtgggga gatggattca taacagacca
11581 tgccttcata aacttcacat ggttccttat gagcttcaaa acttatctcc tatgccattg
11641 gcaaactgaa aagaacaaga cattggggat agtagaggat cccatagaca ggcttatcag
11701 agtagacaat agcttttggc ggatgatgag caaggtgttc ctggaaccca aagtaaaaag
11761 aagacttatg ctttacgata catctgtatt gaatgttctg ggtagtatca gtttcaaaaa
11821 ctggtttgtt agccggttaa gaacagtaga ctacatggag atcccatgga ttgtcaatgc
11881 tgagggtgac atagtcgagc aaaaacctgt cactgaatat ttgaaaataa tggctgcagg
11941 tgtccatgta aaagtcataa tgcttagtta ctccgatatg gcacatgcta tgacacgctt
12001 gctaaggtgc aagaacatgc aagacaatgt gcccaccata aagaaaacag tatctccaac
12061 tgatgtcaca ccctctgtag accccactcg ggccctactg ctgttcccga aagtcatctt
12121 tagtaagttg accactttca atgcaacatg cagtacagct aagcagtctg gcagcaattt
12181 gacaaaaaac tacatgactt taatgccttg gcaccacatc aaccgttata actttgtcca
12241 tagctccaca gggtgtaagg taagtgtaaa gggatgtata ggcaagttga taacaaaact
12301 tgaactaaga attatctact tcatcggtga gggagctggg aatcttatgt ccagaactgc
12361 atgtgaatac cctaatctaa agtttgtata caggagtctg aaagatgcca atgatcatca
12421 tcatcccaca gagtatgtgc gtgtaatggg gagtatcagc agaataatcg accttggtga
12481 agggttggca atggaagcaa ctgatgcaac taagagagaa cattgggatt ttatccacag
12541 agtgtgcaaa gatcctcttc tgctaaccat ctgtgatgct gaactaaaaa acatggagga
12601 cgtcctgcat ttagtgatac agtggaggaa acatgtacta tcttgtaaca tatgcacatc
12661 atatgggact aatgtgtaca tgtttgttaa gtatcatgca caatctgaag caaagaagct
12721 accacatttt gtccgagtag tttcaatata tatcatgcaa gggagtaaac tatcaggatc
12781 ggaatgttat atgttgttaa cattaggtca ccagaacatg gcaccttgct acggagaggt
12841 taggtctgcg aaatcaatca tggctttgac aagtactttt aaacacccct gtagactaga
12901 caaatctgcc atcgaggcca acctgaaatc actagcacct gggttgacac tgccacttag
12961 tgagcctgct atgcaaaagt acttgttgga tctttcaagc ttaagtggaa ttaagaacac
13021 gggggcaacc attgggggaa gcaaagtggt agagaagaag tgggctttgt gcaaagtgtc
13081 aaatatagtg aagtggttaa gtcacgttct gaaaatgccc aaaggtgatt taaattacga
13141 ttttttcgag gtgatagaaa acacataccc agacatggtg aagctattgg acaacttaaa
13201 cccgtcggag ttgaaaaagc tcgtcaaagt caccgggtac atcctgggca caaagtaata
13261 aagcaatatc aactcaacac ataattatca cctgaaacac aactgacctt aaatgaatgt
13321 tagttaataa aaactaaaag ctaaaaattt gatgaatacg gtttttttct cgt
//
