GenomeNet

Database: RefSeq
Entry: NP_001004728
LinkDB: NP_001004728
Original site: NP_001004728 
LOCUS       NP_001004728             315 aa            linear   PRI 21-SEP-2019
DEFINITION  olfactory receptor 5A1 [Homo sapiens].
ACCESSION   NP_001004728 XP_166899
VERSION     NP_001004728.1
DBSOURCE    REFSEQ: accession NM_001004728.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 315)
  AUTHORS   Malnic B, Godfrey PA and Buck LB.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
REFERENCE   2  (residues 1 to 315)
  AUTHORS   Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R,
            Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach
            H, Lancet D and Shamir R.
  TITLE     DEFOG: a practical scheme for deciphering families of genes
  JOURNAL   Genomics 80 (3), 295-302 (2002)
   PUBMED   12213199
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB065804.1.
            On Sep 19, 2004 this sequence version replaced XP_166899.3.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. The nomenclature assigned to the
            olfactory receptor genes and proteins for this organism is
            independent of other organisms. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     Protein         1..315
                     /product="olfactory receptor 5A1"
                     /note="olfactory receptor, family 5, subfamily A, member 1
                     pseudogene; olfactory receptor OR11-249"
                     /calculated_mol_wt=35021
     Site            8
                     /site_type="glycosylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-linked (GlcNAc...) asparagine. {ECO:0000255};
                     propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Site            29..52
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Region          34..311
                     /region_name="7tm_4"
                     /note="Olfactory receptor; cl21561"
                     /db_xref="CDD:304433"
     Region          44..293
                     /region_name="7tm_1"
                     /note="7 transmembrane receptor (rhodopsin family);
                     pfam00001"
                     /db_xref="CDD:278431"
     Site            61..82
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Site            104..123
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Site            143..161
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Site            199..222
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Site            240..262
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     Site            276..295
                     /site_type="transmembrane region"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGJ0.1)"
     CDS             1..315
                     /gene="OR5A1"
                     /gene_synonym="OR11-249; OR5A1P; OST181"
                     /coded_by="NM_001004728.1:1..948"
                     /db_xref="CCDS:CCDS31561.1"
                     /db_xref="GeneID:219982"
                     /db_xref="HGNC:HGNC:8319"
ORIGIN      
        1 msitkawnss svtmfillgf tdhpelqall fvtflgiylt tlawnlalif lirgdthlht
       61 pmyfflsnls fidicyssav apnmltdffw eqktisfvgc aaqffffvgm glseclllta
      121 maydryaais spllyptimt qglctrmvvg ayvggflssl iqassifrlh fcgpniinhf
      181 fcdlppvlal scsdtflsqv vnflvvvtvg gtsflqllis ygyivsavlk ipsaegrwka
      241 cntcashlmv vtllfgtalf vylrpsssyl lgrdkvvsvf yslvipmlnp liyslrnkei
      301 kdalwkvler kkvfs
//
DBGET integrated database retrieval system