LOCUS       NP_001004790             399 aa            linear   VRT 17-DEC-2022
DEFINITION  ubiquitin-like modifier-activating enzyme 5 [Xenopus tropicalis].
ACCESSION   NP_001004790
VERSION     NP_001004790.1
DBSOURCE    REFSEQ: accession NM_001004790.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (residues 1 to 399)
  AUTHORS   Rana AA, Collart C, Gilchrist MJ and Smith JC.
  TITLE     Defining synphenotype groups in Xenopus tropicalis by use of
            antisense morpholino oligonucleotides
  JOURNAL   PLoS Genet 2 (11), e193 (2006)
   PUBMED   17112317
REFERENCE   2  (residues 1 to 399)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC074525.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC074525.1, CR760171.2 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Xenopus tropicalis"
                     /db_xref="taxon:8364"
                     /chromosome="6"
                     /map="6"
     Protein         1..399
                     /product="ubiquitin-like modifier-activating enzyme 5"
                     /note="ubiquitin-activating enzyme E1-domain containing 1;
                     UFM1-activating enzyme; Ubiquitin-activating enzyme 5;
                     Ubiquitin-activating enzyme E1 domain-containing protein
                     1"
                     /calculated_mol_wt=44332
     Region          48..293
                     /region_name="ThiF_MoeB_HesA_family"
                     /note="ThiF_MoeB_HesA. Family of E1-like enzymes involved
                     in molybdopterin and thiamine biosynthesis family. The
                     common reaction mechanism catalyzed by MoeB and ThiF, like
                     other E1 enzymes, begins with a nucleophilic attack of the
                     C-terminal carboxylate of MoaD...; cd00757"
                     /db_xref="CDD:238386"
     Site            order(76,78,80,100,102,111,123,177,183)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:238386"
     Site            order(80,178..180,184,202..203,209,211,278,282,289,
                     291..292)
                     /site_type="other"
                     /note="substrate interface [chemical binding]"
                     /db_xref="CDD:238386"
     Region          331..343
                     /region_name="UFM1-interacting sequence (UIS).
                     /evidence=ECO:0000250|UniProtKB:Q9GZZ9"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6GLG7.1)"
     CDS             1..399
                     /gene="uba5"
                     /gene_synonym="ube1dc1"
                     /coded_by="NM_001004790.1:228..1427"
                     /db_xref="GeneID:448010"
                     /db_xref="Xenbase:XB-GENE-955661"
ORIGIN      
        1 meklieelrs rvseleeelh rvrngeqvhe ghrakintms aevvdsnpys rlmalkrmgi
       61 vedyekirtf tvavvgvggv gsvtaemltr cgigklllfd ydkvemanmn rlffqphqag
      121 lskveaaeht lrninpdvqf evhnynittl dnfqhfmdri skgglkegtp vdlvlscvdn
      181 fearmainta cnelvqiwme sgvsenavsg hiqlikpget acfacapplv vaanidektl
      241 kregvcaasl pttmgvvagm lvqnvlkyll nfgtvsfylg ynamqdffpt mamkpnpqcg
      301 dkycrkqqee fklkeaarpk qepivvkeee ivhedndwgi elvsevseee lkaasgpvpe
      361 lpegikvayt vpiteptsgf ivedseqsld elmaqmknl
//