GenomeNet

Database: RefSeq
Entry: NP_001009025
LinkDB: NP_001009025
Original site: NP_001009025 
LOCUS       NP_001009025             154 aa            linear   PRI 17-FEB-2019
DEFINITION  superoxide dismutase [Cu-Zn] [Pan troglodytes].
ACCESSION   NP_001009025 XP_531539
VERSION     NP_001009025.1
DBSOURCE    REFSEQ: accession NM_001009025.1
KEYWORDS    RefSeq.
SOURCE      Pan troglodytes (chimpanzee)
  ORGANISM  Pan troglodytes
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pan.
REFERENCE   1  (residues 1 to 154)
  AUTHORS   Fukuhara R, Tezuka T and Kageyama T.
  TITLE     Structure, molecular evolution, and gene expression of primate
            superoxide dismutases
  JOURNAL   Gene 296 (1-2), 99-109 (2002)
   PUBMED   12383507
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB087266.1.
            On Jan 6, 2005 this sequence version replaced XP_531539.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB087266.1, CB295510.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01120800, SAMN01120804
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..154
                     /organism="Pan troglodytes"
                     /db_xref="taxon:9598"
                     /chromosome="21"
                     /map="21"
     Protein         1..154
                     /product="superoxide dismutase [Cu-Zn]"
                     /EC_number="1.15.1.1"
                     /note="Cu,Zn-superoxide dismutase; superoxide dismutase 1,
                     soluble (amyotrophic lateral sclerosis 1 (adult))"
                     /calculated_mol_wt=15805
     Site            2
                     /site_type="acetylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylalanine. {ECO:0000250|UniProtKB:P00442};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            4
                     /site_type="modified"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-succinyllysine. {ECO:0000250|UniProtKB:P08228};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            order(6,8,18,20,51..53,114..115)
                     /site_type="other"
                     /note="E-class dimer interface [polypeptide binding]"
                     /db_xref="CDD:238186"
     Site            10
                     /site_type="modified"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-succinyllysine. {ECO:0000250|UniProtKB:P08228};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Region          11..150
                     /region_name="Sod_Cu"
                     /note="Copper/zinc superoxide dismutase (SODC); pfam00080"
                     /db_xref="CDD:306566"
     Site            order(31,89)
                     /site_type="other"
                     /note="P-class dimer interface [polypeptide binding]"
                     /db_xref="CDD:238186"
     Site            order(47,49,64,81,84,121)
                     /site_type="active"
                     /db_xref="CDD:238186"
     Site            order(47,49,64,121)
                     /site_type="other"
                     /note="Cu2+ binding site [ion binding]"
                     /db_xref="CDD:238186"
     Site            order(64,72,81,84)
                     /site_type="other"
                     /note="Zn2+ binding site [ion binding]"
                     /db_xref="CDD:238186"
     Site            92
                     /site_type="modified"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-succinyllysine. {ECO:0000250|UniProtKB:P08228};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            99
                     /site_type="phosphorylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine. {ECO:0000250|UniProtKB:P00441};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            103
                     /site_type="phosphorylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine. {ECO:0000250|UniProtKB:P00441};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            106
                     /site_type="phosphorylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine. {ECO:0000250|UniProtKB:P07632};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            108
                     /site_type="phosphorylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine. {ECO:0000250|UniProtKB:P08228};
                     propagated from UniProtKB/Swiss-Prot (P60052.2)"
     Site            123
                     /site_type="acetylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine, alternate.
                     {ECO:0000250|UniProtKB:P00441}; propagated from
                     UniProtKB/Swiss-Prot (P60052.2)"
     Site            123
                     /site_type="modified"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-succinyllysine, alternate.
                     {ECO:0000250|UniProtKB:P00441}; propagated from
                     UniProtKB/Swiss-Prot (P60052.2)"
     Site            137
                     /site_type="acetylation"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine, alternate.
                     {ECO:0000250|UniProtKB:P08228}; propagated from
                     UniProtKB/Swiss-Prot (P60052.2)"
     Site            137
                     /site_type="modified"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-succinyllysine, alternate.
                     {ECO:0000250|UniProtKB:P08228}; propagated from
                     UniProtKB/Swiss-Prot (P60052.2)"
     CDS             1..154
                     /gene="SOD1"
                     /coded_by="NM_001009025.1:1..465"
                     /db_xref="GeneID:449637"
                     /db_xref="VGNC:VGNC:14681"
ORIGIN      
        1 matkavcvlk gdgpvqgiin feqkesngpv kvwgsikglt eglhgfhvhe fgdntagcts
       61 agphfnplsr khggpkdeer hvgdlgnvta dkdgvadvsi edsvislsgd hciigrtlvv
      121 hekaddlgkg gneestktgn agsrlacgvi giaq
//
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