LOCUS NP_001009547 699 aa linear ROD 04-AUG-2023
DEFINITION a disintegrin and metalloprotease domain 26b precursor [Mus
musculus].
ACCESSION NP_001009547 XP_356073
VERSION NP_001009547.1
DBSOURCE REFSEQ: accession NM_001009547.2
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (residues 1 to 699)
AUTHORS Grayson P and Civetta A.
TITLE Positive selection in the adhesion domain of Mus sperm Adam genes
through gene duplications and function-driven gene complex
formations
JOURNAL BMC Evol Biol 13, 217 (2013)
PUBMED 24079728
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 699)
AUTHORS Choi I, Oh J, Cho BN, Ahnn J, Jung YK, Han Kim D and Cho C.
TITLE Characterization and comparative genomic analysis of intronless
Adams with testicular gene expression
JOURNAL Genomics 83 (4), 636-646 (2004)
PUBMED 15028286
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AK015931.1 and AC134907.5.
On Jan 12, 2005 this sequence version replaced XP_356073.2.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data because no single transcript was available
for the full length of the gene. The extent of this transcript is
supported by transcript alignments and paralogous data.
##Evidence-Data-START##
Transcript exon combination :: AK015931.1, SRR5189685.16469.1
[ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN00849384, SAMN01766828
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..699
/organism="Mus musculus"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="8"
/map="8 23.99 cM"
Protein 1..699
/product="a disintegrin and metalloprotease domain 26b
precursor"
/calculated_mol_wt=76336
sig_peptide 1..22
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
/calculated_mol_wt=2668
Region 29..147
/region_name="Pep_M12B_propep"
/note="Reprolysin family propeptide; pfam01562"
/db_xref="CDD:460254"
Region 195..383
/region_name="ZnMc_adamalysin_II_like"
/note="Zinc-dependent metalloprotease; adamalysin_II_like
subfamily. Adamalysin II is a snake venom zinc
endopeptidase. This subfamily contains other snake venom
metalloproteinases, as well as membrane-anchored
metalloproteases belonging to the ADAM family; cd04269"
/db_xref="CDD:239797"
Site order(329..330,333,339)
/site_type="active"
/db_xref="CDD:239797"
Region 401..473
/region_name="Disintegrin"
/note="pfam00200"
/db_xref="CDD:459709"
Region 477..613
/region_name="ACR"
/note="ADAM Cysteine-Rich Domain; smart00608"
/db_xref="CDD:214743"
CDS 1..699
/gene="Adam26b"
/coded_by="NM_001009547.2:306..2405"
/db_xref="CCDS:CCDS22268.1"
/db_xref="GeneID:382007"
/db_xref="MGI:MGI:3588304"
ORIGIN
1 mflkfclwtm fffsawspig hakysslpev vtplrvtvtr gnntspgwls yslniggqrh
61 iitmkpkknl msrnlillty tqqgdlleqr pfvpndcyyh gyvdedpesl vilntcfgsl
121 qgtleingtt yeimpkssts tfehlaykmd ngdsepspmr cglseeeiaq qrklrernap
181 tllqiphenw wthhrfieyf vvidhkqyvh rnnnittciq dmlqivngvn gyylqidtdv
241 vltaleiwne knyinvelsi fkvlgdfctw kqnmfgnrir hdiihllvrq gyglylglay
301 ladvctpync gvssflsdvm sdmahivahe mghnlgmkhd gigctcglkd clmapyktns
361 pkfsncsyee mysvvtkrsc lydipealvt nltvcgnkvv eegeecdcgs tesclqdpcc
421 ssdcvlkpga qcafglccqd cqflktgtvc reeknecdlp ewcngtsaec pgdvykadgi
481 pcsgegycyk mechqrdeqc rkifgngsrs adeicymemn rrgdrfgncg ndsskykice
541 ladvlcgriq cenviqlpqr rnhetvhyth fsnvtcwtmd yhfgitiddi gavsdgtaca
601 pyhicvdrkc vsksdlvsnc ttklchmqgv cnnknhchct ntweppdcql rghggsldsg
661 ppplhvpnss wafyfisfft illvitislv gitkrvkmn
//