GenomeNet

Database: RefSeq
Entry: NP_001030765
LinkDB: NP_001030765
Original site: NP_001030765 
LOCUS       NP_001030765             278 aa            linear   PLN 14-FEB-2019
DEFINITION  glyoxylate reductase 1 [Arabidopsis thaliana].
ACCESSION   NP_001030765
VERSION     NP_001030765.1
DBLINK      BioProject: PRJNA116
            BioSample: SAMN03081427
DBSOURCE    REFSEQ: accession NM_001035688.1
KEYWORDS    RefSeq.
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (residues 1 to 278)
  AUTHORS   Salanoubat,M., Lemcke,K., Rieger,M., Ansorge,W., Unseld,M.,
            Fartmann,B., Valle,G., Blocker,H., Perez-Alonso,M., Obermaier,B.,
            Delseny,M., Boutry,M., Grivell,L.A., Mache,R., Puigdomenech,P., De
            Simone,V., Choisne,N., Artiguenave,F., Robert,C., Brottier,P.,
            Wincker,P., Cattolico,L., Weissenbach,J., Saurin,W., Quetier,F.,
            Schafer,M., Muller-Auer,S., Gabel,C., Fuchs,M., Benes,V.,
            Wurmbach,E., Drzonek,H., Erfle,H., Jordan,N., Bangert,S.,
            Wiedelmann,R., Kranz,H., Voss,H., Holland,R., Brandt,P.,
            Nyakatura,G., Vezzi,A., D'Angelo,M., Pallavicini,A., Toppo,S.,
            Simionati,B., Conrad,A., Hornischer,K., Kauer,G., Lohnert,T.H.,
            Nordsiek,G., Reichelt,J., Scharfe,M., Schon,O., Bargues,M.,
            Terol,J., Climent,J., Navarro,P., Collado,C., Perez-Perez,A.,
            Ottenwalder,B., Duchemin,D., Cooke,R., Laudie,M., Berger-Llauro,C.,
            Purnelle,B., Masuy,D., de Haan,M., Maarse,A.C., Alcaraz,J.P.,
            Cottet,A., Casacuberta,E., Monfort,A., Argiriou,A., flores,M.,
            Liguori,R., Vitale,D., Mannhaupt,G., Haase,D., Schoof,H., Rudd,S.,
            Zaccaria,P., Mewes,H.W., Mayer,K.F., Kaul,S., Town,C.D., Koo,H.L.,
            Tallon,L.J., Jenkins,J., Rooney,T., Rizzo,M., Walts,A.,
            Utterback,T., Fujii,C.Y., Shea,T.P., Creasy,T.H., Haas,B.,
            Maiti,R., Wu,D., Peterson,J., Van Aken,S., Pai,G., Militscher,J.,
            Sellers,P., Gill,J.E., Feldblyum,T.V., Preuss,D., Lin,X.,
            Nierman,W.C., Salzberg,S.L., White,O., Venter,J.C., Fraser,C.M.,
            Kaneko,T., Nakamura,Y., Sato,S., Kato,T., Asamizu,E., Sasamoto,S.,
            Kimura,T., Idesawa,K., Kawashima,K., Kishida,Y., Kiyokawa,C.,
            Kohara,M., Matsumoto,M., Matsuno,A., Muraki,A., Nakayama,S.,
            Nakazaki,N., Shinpo,S., Takeuchi,C., Wada,T., Watanabe,A.,
            Yamada,M., Yasuda,M. and Tabata,S.
  CONSRTM   European Union Chromosome 3 Arabidopsis Sequencing Consortium;
            Institute for Genomic Research; Kazusa DNA Research Institute
  TITLE     Sequence and analysis of chromosome 3 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 408 (6814), 820-822 (2000)
   PUBMED   11130713
REFERENCE   2  (residues 1 to 278)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2019) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 278)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
REFERENCE   4  (residues 1 to 278)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
            The reference sequence is identical to AEE77022.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Arabidopsis thaliana"
                     /db_xref="taxon:3702"
                     /chromosome="3"
                     /ecotype="Columbia"
     Protein         1..278
                     /product="glyoxylate reductase 1"
                     /calculated_mol_wt=29388
     Region          1..274
                     /region_name="MmsB"
                     /note="3-hydroxyisobutyrate dehydrogenase or related
                     beta-hydroxyacid dehydrogenase [Lipid transport and
                     metabolism]; COG2084"
                     /db_xref="CDD:224995"
     Region          1..150
                     /region_name="NAD_binding_2"
                     /note="NAD binding domain of 6-phosphogluconate
                     dehydrogenase; pfam03446"
                     /db_xref="CDD:281445"
     Region          153..273
                     /region_name="NAD_binding_11"
                     /note="NAD-binding of NADP-dependent 3-hydroxyisobutyrate
                     dehydrogenase; pfam14833"
                     /db_xref="CDD:291499"
     CDS             1..278
                     /gene="GLYR1"
                     /locus_tag="AT3G25530"
                     /gene_synonym="ATGHBDH; AtGLYR1; GHBDH; glyoxylate
                     reductase 1; GLYOXYLATE REDUCTASE 1; GR1"
                     /coded_by="NM_001035688.1:80..916"
                     /inference="Similar to RNA sequence,
                     EST:INSD:DR257435.1,INSD:BP589640.1,INSD:EH908296.1,
                     INSD:AV562967.1,INSD:EL181052.1,INSD:EL179064.1,
                     INSD:AV567204.1,INSD:EL308724.1,INSD:EL158453.1,
                     INSD:EH875945.1,INSD:ES143764.1,INSD:AI100000.1,
                     INSD:AV810222.1,INSD:BP625190.1,INSD:EH974963.1,
                     INSD:AV782696.1,INSD:EL252894.1,INSD:CB258349.1,
                     INSD:ES094439.1,INSD:BP790528.1,INSD:BP586913.1,
                     INSD:EH963044.1,INSD:AV793161.1,INSD:AV788961.1,
                     INSD:EL024665.1,INSD:AV789781.1,INSD:EH919090.1,
                     INSD:ES101387.1,INSD:AV562975.1,INSD:CF773924.1,
                     INSD:AV790659.1,INSD:ES120061.1,INSD:ES013890.1,
                     INSD:EL256237.1,INSD:ES170155.1,INSD:EL266453.1,
                     INSD:EH882102.1,INSD:ES123139.1,INSD:EH860892.1,
                     INSD:AV545347.1,INSD:BP597614.1,INSD:EL311622.1,
                     INSD:EL259054.1,INSD:EH919500.1,INSD:EH934201.1,
                     INSD:ES031775.1,INSD:ES013933.1,INSD:EG471940.1,
                     INSD:EL260988.1,INSD:ES148247.1,INSD:BP668116.1,
                     INSD:BP585362.1,INSD:EL194453.1,INSD:CB257821.1,
                     INSD:EL062550.1,INSD:EL194313.1,INSD:BP561081.2,
                     INSD:EL039976.1,INSD:ES052819.1,INSD:ES015220.1,
                     INSD:ES125756.1,INSD:BP580050.1,INSD:AV797777.1,
                     INSD:ES041925.1,INSD:EH836369.1,INSD:AI997789.1,
                     INSD:ES139744.1,INSD:ES070273.1,INSD:BE527217.1,
                     INSD:AV784788.1"
                     /note="glyoxylate reductase 1 (GLYR1); FUNCTIONS IN:
                     3-hydroxybutyrate dehydrogenase activity, phosphogluconate
                     dehydrogenase (decarboxylating) activity; INVOLVED IN:
                     response to oxidative stress; LOCATED IN: cytosol;
                     EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15
                     growth stages; CONTAINS InterPro DOMAIN/s:
                     6-phosphogluconate dehydrogenase, NAD-binding
                     (InterPro:IPR006115), 6-phosphogluconate dehydrogenase,
                     C-terminal-like (InterPro:IPR008927), Dehydrogenase,
                     multihelical (InterPro:IPR013328), 3-hydroxyacid
                     dehydrogenase/reductase (InterPro:IPR015815),
                     NAD(P)-binding domain (InterPro:IPR016040),
                     3-hydroxyisobutyrate dehydrogenase-related, conserved site
                     (InterPro:IPR002204); BEST Arabidopsis thaliana protein
                     match is: glyoxylate reductase 2 (TAIR:AT1G17650.1); Has
                     35333 Blast hits to 34131 proteins in 2444 species: Archae
                     - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991;
                     Plants - 531; Viruses - 0; Other Eukaryotes - 9610
                     (source: NCBI BLink)."
                     /db_xref="GeneID:822139"
                     /db_xref="TAIR:AT3G25530"
                     /db_xref="Araport:AT3G25530"
ORIGIN      
        1 mevgflglgi mgkamsmnll kngfkvtvwn rtlskcdelv ehgasvcesp aevikkckyt
       61 iamlsdpcaa lsicegkgyi dmstvdaets lkineaitgk ggrfvegpvs gskkpaedgq
      121 liilaagdka lfeesipafd vlgkrsfylg qvgngakmkl ivnmimgsmm nafseglvla
      181 dksglssdtl ldildlgamt npmfkgkgps mnkssyppaf plkhqqkdmr lalalgdena
      241 vsmpvaaaan eafkkarslg lgdldfsavi eavkfsre
//
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