GenomeNet

Database: RefSeq
Entry: NP_001092210
LinkDB: NP_001092210
Original site: NP_001092210 
LOCUS       NP_001092210             280 aa            linear   VRT 27-JAN-2019
DEFINITION  succinate dehydrogenase [ubiquinone] iron-sulfur subunit,
            mitochondrial precursor [Danio rerio].
ACCESSION   NP_001092210 XP_690641
VERSION     NP_001092210.1
DBSOURCE    REFSEQ: accession NM_001098740.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Danio.
REFERENCE   1  (residues 1 to 280)
  AUTHORS   Cao F, Wu P, Huang L, Li H, Qian L, Pang S and Qiu L.
  TITLE     Short-term developmental effects and potential mechanisms of
            azoxystrobin in larval and adult zebrafish (Danio rerio)
  JOURNAL   Aquat. Toxicol. 198, 129-140 (2018)
   PUBMED   29529468
REFERENCE   2  (residues 1 to 280)
  AUTHORS   Cheng ZX, Chu X, Wang SN, Peng XX and Li H.
  TITLE     Six genes of ompA family shuffling for development of polyvalent
            vaccines against Vibrio alginolyticus and Edwardsiella tarda
  JOURNAL   Fish Shellfish Immunol. 75, 308-315 (2018)
   PUBMED   29438846
REFERENCE   3  (residues 1 to 280)
  AUTHORS   Yao H, Yu J, Zhou Y, Xiang Q and Xu C.
  TITLE     The embryonic developmental effect of sedaxane on zebrafish (Danio
            rerio)
  JOURNAL   Chemosphere 197, 299-305 (2018)
   PUBMED   29360593
REFERENCE   4  (residues 1 to 280)
  AUTHORS   Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A,
            Choudhary JS, Emes RD and Grant SG.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 280)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 280)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   7  (residues 1 to 280)
  AUTHORS   Cambier S, Gonzalez P, Mesmer-Dudons N, Brethes D, Fujimura M and
            Bourdineaud JP.
  TITLE     Effects of dietary methylmercury on the zebrafish brain:
            histological, mitochondrial, and gene transcription analyses
  JOURNAL   Biometals 25 (1), 165-180 (2012)
   PUBMED   21947502
REFERENCE   8  (residues 1 to 280)
  AUTHORS   Lerebours A, Adam-Guillermin C, Brethes D, Frelon S, Floriani M,
            Camilleri V, Garnier-Laplace J and Bourdineaud JP.
  TITLE     Mitochondrial energetic metabolism perturbations in skeletal
            muscles and brain of zebrafish (Danio rerio) exposed to low
            concentrations of waterborne uranium
  JOURNAL   Aquat. Toxicol. 100 (1), 66-74 (2010)
   PUBMED   20701985
REFERENCE   9  (residues 1 to 280)
  AUTHORS   Sato Y, Hashiguchi Y and Nishida M.
  TITLE     Temporal pattern of loss/persistence of duplicate genes involved in
            signal transduction and metabolic pathways after teleost-specific
            genome duplication
  JOURNAL   BMC Evol. Biol. 9, 127 (2009)
   PUBMED   19500364
  REMARK    Publication Status: Online-Only
REFERENCE   10 (residues 1 to 280)
  AUTHORS   Cambier S, Benard G, Mesmer-Dudons N, Gonzalez P, Rossignol R,
            Brethes D and Bourdineaud JP.
  TITLE     At environmental doses, dietary methylmercury inhibits
            mitochondrial energy metabolism in skeletal muscles of the zebra
            fish (Danio rerio)
  JOURNAL   Int. J. Biochem. Cell Biol. 41 (4), 791-799 (2009)
   PUBMED   18765295
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC142799.1.
            On Jun 20, 2007 this sequence version replaced XP_690641.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC142799.1, EH435712.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Danio rerio"
                     /db_xref="taxon:7955"
                     /chromosome="22"
                     /map="22"
     Protein         1..280
                     /product="succinate dehydrogenase [ubiquinone] iron-sulfur
                     subunit, mitochondrial precursor"
                     /EC_number="1.3.5.1"
                     /note="Iron-sulfur subunit of complex II; Succinate
                     dehydrogenase [ubiquinone] iron-sulfur subunit,
                     mitochondrial"
                     /calculated_mol_wt=29075
     transit_peptide 1..25
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Mitochondrion. {ECO:0000250}; propagated from
                     UniProtKB/Swiss-Prot (A5PL98.1)"
                     /calculated_mol_wt=2683
     mat_peptide     26..280
                     /product="Succinate dehydrogenase [ubiquinone] iron-sulfur
                     subunit, mitochondrial"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (A5PL98.1)"
                     /calculated_mol_wt=29075
     Region          40..271
                     /region_name="sdhB"
                     /note="succinate dehydrogenase iron-sulfur subunit;
                     Reviewed; PRK05950"
                     /db_xref="CDD:235652"
     Region          40..146
                     /region_name="Fer2_3"
                     /note="2Fe-2S iron-sulfur cluster binding domain;
                     pfam13085"
                     /db_xref="CDD:289830"
     Site            order(88..89,92,95,97..100)
                     /site_type="active"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     Region          184..257
                     /region_name="Fer4_17"
                     /note="4Fe-4S dicluster domain; pfam13534"
                     /db_xref="CDD:290268"
     CDS             1..280
                     /gene="sdhb"
                     /gene_synonym="fj46d06; Ip; wu:fj46d06"
                     /coded_by="NM_001098740.1:13..855"
                     /db_xref="GeneID:562149"
                     /db_xref="ZFIN:ZDB-GENE-030131-8005"
ORIGIN      
        1 maavcfslsr ccsavhrpav tavrfaqtaa apaaqprikk fqiyrwdpdt vgdkprmqty
       61 eidlntcgpm vldalikikn emdstltfrr scregicgsc amninggntl aclnkidtnt
      121 skvtkiyplp hmyvvkdlvp dmsnfyaqyk siepylkkkd esqqgkqqyl qsvedrqkld
      181 glyecilcac cstscpsyww nadkylgpav lmqayrwmid srddftedrl sklqdpfsly
      241 rchtimnctr tcpkglnpgk aiaeikkmmv tykqkdavaa
//
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