GenomeNet

Database: RefSeq
Entry: NP_001098423
LinkDB: NP_001098423
Original site: NP_001098423 
LOCUS       NP_001098423             280 aa            linear   MAM 02-APR-2025
DEFINITION  succinate dehydrogenase [ubiquinone] iron-sulfur subunit,
            mitochondrial precursor [Sus scrofa].
ACCESSION   NP_001098423
VERSION     NP_001098423.1
DBSOURCE    REFSEQ: accession NM_001104953.1
KEYWORDS    RefSeq.
SOURCE      Sus scrofa (pig)
  ORGANISM  Sus scrofa
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae;
            Sus.
REFERENCE   1  (residues 1 to 280)
  AUTHORS   An,Q.C. and Liu,G.Y.
  TITLE     Molecular cloning, sequence identification, and tissue expression
            profile analysis of three novel porcine genes: SDHB, SNRPA and
            CRYBB1
  JOURNAL   Mol Biol Rep 36 (4), 683-690 (2009)
   PUBMED   18360780
  REMARK    GeneRIF: tissue expression analysis indicated that that swine SDHB,
            SNRPA and CRYBB1 gene were differentially expressed in tissues
            including fat, lung, muscle, small intestine, kidney, large
            intestine, spleen and liver
REFERENCE   2  (residues 1 to 280)
  AUTHORS   Huo,X., Su,D., Wang,A., Zhai,Y., Xu,J., Li,X., Bartlam,M., Sun,F.
            and Rao,Z.
  TITLE     Preliminary molecular characterization and crystallization of
            mitochondrial respiratory complex II from porcine heart
  JOURNAL   FEBS J 274 (6), 1524-1529 (2007)
   PUBMED   17480203
  REMARK    GeneRIF: The gene sequences of each complex II subunit were
            measured by RT-PCR. N-terminal sequencing work was performed to
            identify the mitochondrial targeting signal peptide of each
            subunit.
REFERENCE   3  (residues 1 to 280)
  AUTHORS   Uenishi,H., Eguchi-Ogawa,T., Shinkai,H., Okumura,N., Suzuki,K.,
            Toki,D., Hamasima,N. and Awata,T.
  TITLE     PEDE (Pig EST Data Explorer) has been expanded into Pig Expression
            Data Explorer, including 10 147 porcine full-length cDNA sequences
  JOURNAL   Nucleic Acids Res 35 (Database issue), D650-D653 (2007)
   PUBMED   17145712
REFERENCE   4  (residues 1 to 280)
  AUTHORS   Kullberg,M., Nilsson,M.A., Arnason,U., Harley,E.H. and Janke,A.
  TITLE     Housekeeping genes for phylogenetic analysis of eutherian
            relationships
  JOURNAL   Mol Biol Evol 23 (8), 1493-1503 (2006)
   PUBMED   16751257
REFERENCE   5  (residues 1 to 280)
  AUTHORS   Sun,F., Huo,X., Zhai,Y., Wang,A., Xu,J., Su,D., Bartlam,M. and
            Rao,Z.
  TITLE     Crystal structure of mitochondrial respiratory membrane protein
            complex II
  JOURNAL   Cell 121 (7), 1043-1057 (2005)
   PUBMED   15989954
REFERENCE   6  (residues 1 to 280)
  AUTHORS   Uenishi,H., Eguchi,T., Suzuki,K., Sawazaki,T., Toki,D., Shinkai,H.,
            Okumura,N., Hamasima,N. and Awata,T.
  TITLE     PEDE (Pig EST Data Explorer): construction of a database for ESTs
            derived from porcine full-length cDNA libraries
  JOURNAL   Nucleic Acids Res 32 (Database issue), D484-D488 (2004)
   PUBMED   14681463
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ915498.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ915498.1, AK232406.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN02364669, SAMN02364670
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Sus scrofa"
                     /db_xref="taxon:9823"
                     /chromosome="6"
                     /map="6"
     Protein         1..280
                     /product="succinate dehydrogenase [ubiquinone] iron-sulfur
                     subunit, mitochondrial precursor"
                     /EC_number="1.3.5.1"
                     /note="Iron-sulfur subunit of complex II; Succinate
                     dehydrogenase [ubiquinone] iron-sulfur subunit,
                     mitochondrial; malate dehydrogenase [quinone] iron-sulfur
                     subunit"
                     /calculated_mol_wt=28725
     transit_peptide 1..28
                     /note="Mitochondrion; propagated from UniProtKB/Swiss-Prot
                     (Q007T0.1)"
                     /calculated_mol_wt=2878
     mat_peptide     29..280
                     /product="Succinate dehydrogenase [ubiquinone] iron-sulfur
                     subunit, mitochondrial. /id=PRO_0000343799"
                     /note="propagated from UniProtKB/Swiss-Prot (Q007T0.1)"
                     /calculated_mol_wt=28725
     Region          29..271
                     /region_name="PLN00129"
                     /note="succinate dehydrogenase [ubiquinone] iron-sulfur
                     subunit"
                     /db_xref="CDD:215067"
     Site            51
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:Q9CQA3; propagated from
                     UniProtKB/Swiss-Prot (Q007T0.1)"
     Site            55
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:Q9CQA3; propagated from
                     UniProtKB/Swiss-Prot (Q007T0.1)"
     Region          146..218
                     /region_name="Interaction with SDHAF1.
                     /evidence=ECO:0000250|UniProtKB:P21912"
                     /note="propagated from UniProtKB/Swiss-Prot (Q007T0.1)"
     CDS             1..280
                     /gene="SDHB"
                     /gene_synonym="Ip"
                     /coded_by="NM_001104953.1:1..843"
                     /db_xref="GeneID:414412"
                     /db_xref="RGD:14076668"
                     /db_xref="VGNC:VGNC:92659"
ORIGIN      
        1 maavvavslk rwfpattlgg aclqacrgaq taaataprik kfaiyrwdpd ktgdkphmqt
       61 yeidlnncgp mvldalikik neidstltfr rscregicgs camninggnt lactrridtn
      121 ldkvskiypl phmyvikdlv pdlsnfyaqy ksiepylkkk desqegkqqy lqsieerekl
      181 dglyecilca ccstscpsyw wngdkylgpa vlmqayrwmi dsrddfteer laklqdpfsl
      241 yrchtimnct gtcpkglnpg kaiaeikkmm atykekkasa
//
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