LOCUS NP_001098423 280 aa linear MAM 09-DEC-2018
DEFINITION succinate dehydrogenase [ubiquinone] iron-sulfur subunit,
mitochondrial precursor [Sus scrofa].
ACCESSION NP_001098423
VERSION NP_001098423.1
DBSOURCE REFSEQ: accession NM_001104953.1
KEYWORDS RefSeq.
SOURCE Sus scrofa (pig)
ORGANISM Sus scrofa
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
Sus.
REFERENCE 1 (residues 1 to 280)
AUTHORS An QC and Liu GY.
TITLE Molecular cloning, sequence identification, and tissue expression
profile analysis of three novel porcine genes: SDHB, SNRPA and
CRYBB1
JOURNAL Mol. Biol. Rep. 36 (4), 683-690 (2009)
PUBMED 18360780
REMARK GeneRIF: tissue expression analysis indicated that that swine SDHB,
SNRPA and CRYBB1 gene were differentially expressed in tissues
including fat, lung, muscle, small intestine, kidney, large
intestine, spleen and liver
REFERENCE 2 (residues 1 to 280)
AUTHORS Huo X, Su D, Wang A, Zhai Y, Xu J, Li X, Bartlam M, Sun F and Rao
Z.
TITLE Preliminary molecular characterization and crystallization of
mitochondrial respiratory complex II from porcine heart
JOURNAL FEBS J. 274 (6), 1524-1529 (2007)
PUBMED 17480203
REMARK GeneRIF: The gene sequences of each complex II subunit were
measured by RT-PCR. N-terminal sequencing work was performed to
identify the mitochondrial targeting signal peptide of each
subunit.
REFERENCE 3 (residues 1 to 280)
AUTHORS Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D,
Hamasima N and Awata T.
TITLE PEDE (Pig EST Data Explorer) has been expanded into Pig Expression
Data Explorer, including 10 147 porcine full-length cDNA sequences
JOURNAL Nucleic Acids Res. 35 (Database issue), D650-D653 (2007)
PUBMED 17145712
REFERENCE 4 (residues 1 to 280)
AUTHORS Kullberg M, Nilsson MA, Arnason U, Harley EH and Janke A.
TITLE Housekeeping genes for phylogenetic analysis of eutherian
relationships
JOURNAL Mol. Biol. Evol. 23 (8), 1493-1503 (2006)
PUBMED 16751257
REFERENCE 5 (residues 1 to 280)
AUTHORS Sun F, Huo X, Zhai Y, Wang A, Xu J, Su D, Bartlam M and Rao Z.
TITLE Crystal structure of mitochondrial respiratory membrane protein
complex II
JOURNAL Cell 121 (7), 1043-1057 (2005)
PUBMED 15989954
REFERENCE 6 (residues 1 to 280)
AUTHORS Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H,
Okumura N, Hamasima N and Awata T.
TITLE PEDE (Pig EST Data Explorer): construction of a database for ESTs
derived from porcine full-length cDNA libraries
JOURNAL Nucleic Acids Res. 32 (Database issue), D484-D488 (2004)
PUBMED 14681463
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from DQ915498.1.
##Evidence-Data-START##
Transcript exon combination :: DQ915498.1, AK232406.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN02364669, SAMN02364670
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
gene product(s) localized to mito. :: inferred from homology
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..280
/organism="Sus scrofa"
/db_xref="taxon:9823"
/chromosome="6"
/map="6"
Protein 1..280
/product="succinate dehydrogenase [ubiquinone] iron-sulfur
subunit, mitochondrial precursor"
/EC_number="1.3.5.1"
/note="Iron-sulfur subunit of complex II; Succinate
dehydrogenase [ubiquinone] iron-sulfur subunit,
mitochondrial"
/calculated_mol_wt=28725
transit_peptide 1..28
/experiment="experimental evidence, no additional details
recorded"
/note="Mitochondrion; propagated from UniProtKB/Swiss-Prot
(Q007T0.1)"
/calculated_mol_wt=2878
mat_peptide 29..280
/product="Succinate dehydrogenase [ubiquinone] iron-sulfur
subunit, mitochondrial"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q007T0.1)"
/calculated_mol_wt=28725
Region 41..272
/region_name="sdhB"
/note="succinate dehydrogenase iron-sulfur subunit;
Reviewed; PRK05950"
/db_xref="CDD:235652"
Region 41..147
/region_name="Fer2_3"
/note="2Fe-2S iron-sulfur cluster binding domain;
pfam13085"
/db_xref="CDD:289830"
Site 51
/site_type="other"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine. {ECO:0000250|UniProtKB:Q9CQA3};
propagated from UniProtKB/Swiss-Prot (Q007T0.1)"
Site 55
/site_type="other"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine. {ECO:0000250|UniProtKB:Q9CQA3};
propagated from UniProtKB/Swiss-Prot (Q007T0.1)"
Site order(89..90,93,96,98..101)
/site_type="active"
/note="catalytic loop [active]"
/db_xref="CDD:238126"
Region 185..258
/region_name="Fer4_17"
/note="4Fe-4S dicluster domain; pfam13534"
/db_xref="CDD:290268"
CDS 1..280
/gene="SDHB"
/gene_synonym="Ip"
/coded_by="NM_001104953.1:1..843"
/db_xref="GeneID:414412"
ORIGIN
1 maavvavslk rwfpattlgg aclqacrgaq taaataprik kfaiyrwdpd ktgdkphmqt
61 yeidlnncgp mvldalikik neidstltfr rscregicgs camninggnt lactrridtn
121 ldkvskiypl phmyvikdlv pdlsnfyaqy ksiepylkkk desqegkqqy lqsieerekl
181 dglyecilca ccstscpsyw wngdkylgpa vlmqayrwmi dsrddfteer laklqdpfsl
241 yrchtimnct gtcpkglnpg kaiaeikkmm atykekkasa
//
