LOCUS       NP_001128347             426 aa            linear   PRI 28-DEC-2022
DEFINITION  tubulin epsilon and delta complex protein 1 isoform 1 [Homo
            sapiens].
ACCESSION   NP_001128347
VERSION     NP_001128347.1
DBSOURCE    REFSEQ: accession NM_001134875.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 426)
  AUTHORS   Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC,
            Han K, Li A, Hess GT, Bassik MC, Chen JK and Nachury MV.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
REFERENCE   2  (residues 1 to 426)
  AUTHORS   Filipuzzi I, Thomas JR, Pries V, Estoppey D, Salcius M, Studer C,
            Schirle M and Hoepfner D.
  TITLE     Direct Interaction of Chivosazole F with Actin Elicits Cell
            Responses Similar to Latrunculin A but Distinct from Chondramide
  JOURNAL   ACS Chem Biol 12 (9), 2264-2269 (2017)
   PUBMED   28796488
REFERENCE   3  (residues 1 to 426)
  AUTHORS   Behrends C, Sowa ME, Gygi SP and Harper JW.
  TITLE     Network organization of the human autophagy system
  JOURNAL   Nature 466 (7302), 68-76 (2010)
   PUBMED   20562859
REFERENCE   4  (residues 1 to 426)
  AUTHORS   DeGrado-Warren J, Dufford M, Chen J, Bartel PL, Shattuck D and
            Frech GC.
  TITLE     Construction and characterization of a normalized yeast two-hybrid
            library derived from a human protein-coding clone collection
  JOURNAL   Biotechniques 44 (2), 265-273 (2008)
   PUBMED   18330356
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928654.1 and AW236560.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.503928.1,
                                           SRR14038194.1475267.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.33"
     Protein         1..426
                     /product="tubulin epsilon and delta complex protein 1
                     isoform 1"
                     /note="uncharacterized protein C14orf80; tubulin epsilon
                     and delta complex protein 1"
                     /calculated_mol_wt=46901
     Region          90..262
                     /region_name="DUF4509"
                     /note="Domain of unknown function (DUF4509); pfam14970"
                     /db_xref="CDD:434359"
     CDS             1..426
                     /gene="TEDC1"
                     /gene_synonym="C14orf80"
                     /coded_by="NM_001134875.2:131..1411"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS45181.1"
                     /db_xref="GeneID:283643"
                     /db_xref="HGNC:HGNC:20127"
ORIGIN      
        1 mgrrrqrvdp aagaragalp eaiaalsrsl psgpspeifr rakfdrpeat salwqllfrv
       61 lsplpagnal aslalevqar lvksalcsqg yprlalaqlp edgsqgsrel llalswllar
      121 gpvpeqmlaq arvplgdemt vcqcealasp gppaphmeae gpvdvrhvqw lmgklrfrwr
      181 qlvssqqeqc allskihlyt rgchsdqsls hlsvteaeml rdpeggqqll rtlerenqrl
      241 eavlawrrse lvfwrwmdtv lgtcapevpa aasqptflpw vpergggeld lvvrelqale
      301 eelreaaerr raaweakagg cgrgpewsaa rrasreavek elgalqqcwe rdggpaqphg
      361 phrlvrredg aagdrdlraa vvirtlrsqe acleavlrrl qgqcrqelar lvgarpgliw
      421 ipppgr
//