LOCUS NP_010484 479 aa linear PLN 15-SEP-2023
DEFINITION protein-lysine N-methyltransferase [Saccharomyces cerevisiae
S288C].
ACCESSION NP_010484
VERSION NP_010484.1
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001180506.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 479)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 479)
AUTHORS Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
JOURNAL Nature 387 (6632 SUPPL), 75-78 (1997)
PUBMED 9169867
REFERENCE 3 (residues 1 to 479)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 4 (residues 1 to 479)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (14-SEP-2023) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 479)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2015) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 479)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2013) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 7 (residues 1 to 479)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 8 (residues 1 to 479)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 9 (residues 1 to 479)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA12041.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..479
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="IV"
Protein 1..479
/product="protein-lysine N-methyltransferase"
/calculated_mol_wt=55819
Region 20..340
/region_name="SET_SETD4"
/note="SET domain found in SET domain-containing protein 4
(SETD4) and similar proteins; cd19177"
/db_xref="CDD:380954"
Site order(33..34,246..247,271..276,324,336,338)
/site_type="other"
/note="putative SAM binding site"
/db_xref="CDD:380954"
Site order(33..34,52,244..249,271..275,285,322..325)
/site_type="active"
/note="putative active site [active]"
/db_xref="CDD:380954"
CDS 1..479
/gene="RKM2"
/locus_tag="YDR198C"
/coded_by="NM_001180506.1:1..1440"
/experiment="EXISTENCE:direct assay:GO:0016279
protein-lysine N-methyltransferase activity
[PMID:17005568]"
/experiment="EXISTENCE:direct assay:GO:0018026
peptidyl-lysine monomethylation [PMID:17005568]"
/experiment="EXISTENCE:mutant phenotype:GO:0018023
peptidyl-lysine trimethylation [PMID:17005568]"
/note="Ribosomal protein lysine methyltransferase;
responsible for trimethylation of the lysine residue at
position 3 of Rpl12Ap and Rpl12Bp"
/db_xref="GeneID:851779"
/db_xref="SGD:S000002606"
ORIGIN
1 megkvdvllt wlkksdkfyi apnisicesp etgrgivlsh gsirkndiiv svpsskqlnf
61 htilyhiskf nkelnipgit idrkpinyed niieaenkaw adpryglyse lskefllsls
121 sfqlvsfyil venfllpkwt hneiysdwkp ffdvwpsmee lrsipaiwnc dpnsryhsli
181 eylpaasrkh marisglvre dwetisevvl kwneiygsls ctknsdkfts delfslfvhv
241 yfiinsrcly akiplkieds psnftlvpyv dfmnhicesd lhcypqlspq lrsegeniig
301 igqftircgd hlydnineel flnygahsnd fllneygfvv dgnkwnyldi sdeiielidd
361 dkkevktfll ehdywgdyti netdisyrif valnyyvtrd errvrkfieg yisedyfkpk
421 issvlkellv sltakytktl seltekvsnl ennlclqnli tiykgyikil tqhlqdlqs
//
