GenomeNet

Database: RefSeq
Entry: NP_013976
LinkDB: NP_013976
Original site: NP_013976 
LOCUS       NP_013976                585 aa            linear   PLN 04-APR-2018
DEFINITION  glutamate decarboxylase GAD1 [Saccharomyces cerevisiae S288C].
ACCESSION   NP_013976
VERSION     NP_013976.1
DBLINK      BioProject: PRJNA128
DBSOURCE    REFSEQ: accession NM_001182756.1
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (residues 1 to 585)
  AUTHORS   Bowman,S., Churcher,C., Badcock,K., Brown,D., Chillingworth,T.,
            Connor,R., Dedman,K., Devlin,K., Gentles,S., Hamlin,N., Hunt,S.,
            Jagels,K., Lye,G., Moule,S., Odell,C., Pearson,D., Rajandream,M.,
            Rice,P., Skelton,J., Walsh,S., Whitehead,S. and Barrell,B.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII
  JOURNAL   Nature 387 (6632 SUPPL), 90-93 (1997)
   PUBMED   9169872
REFERENCE   2  (residues 1 to 585)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (residues 1 to 585)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (residues 1 to 585)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   5  (residues 1 to 585)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   6  (residues 1 to 585)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to DAA10150.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-2-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..585
                     /organism="Saccharomyces cerevisiae S288C"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XIII"
     Protein         1..585
                     /product="glutamate decarboxylase GAD1"
                     /EC_number="4.1.1.15"
                     /calculated_mol_wt=65859
     Region          41..522
                     /region_name="Glu-decarb-GAD"
                     /note="glutamate decarboxylase; TIGR01788"
                     /db_xref="CDD:130848"
     Site            order(154..155,158,238,277,280,315,318)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:99742"
     Site            318
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99742"
     CDS             1..585
                     /gene="GAD1"
                     /locus_tag="YMR250W"
                     /coded_by="NM_001182756.1:1..1758"
                     /note="Glutamate decarboxylase; converts glutamate into
                     gamma-aminobutyric acid (GABA) during glutamate
                     catabolism; involved in response to oxidative stress"
                     /db_xref="GeneID:855291"
                     /db_xref="SGD:S000004862"
ORIGIN      
        1 mlhrhgskqk nfeniagkvv hdlaglqlls ndvqksavqs ghqgsnnmrd tssqgmanky
       61 svpkkglpad lsyqlihnel tldgnphlnl asfvntfttd qarklidenl tknladndey
      121 pqlieltqrc ismlaqlwha npdeepigca ttgsseaiml gglamkkrwe hrmknagkda
      181 skpniimssa cqvalekftr yfevecrlvp vshrshhmld peslwdyvde ntigcfvilg
      241 ttytghlenv ekvadvlsqi eakhpdwsnt dipihadgas ggfiipfgfe kehmkaygme
      301 rwgfnhprvv smntsghkfg lttpglgwvl wrdesllade lrfklkylgg veetfglnfs
      361 rpgfqvvhqy fnfvslghsg yrtqfqnslf varafsfell nssklpgcfe ivssihesie
      421 ndsapksvkd ywehpqaykp gvplvafkls kkfheeypev pqailssllr grgwiipnyp
      481 lpkatdgsde kevlrvvfrs emkldlaqll ivdiesiltk lihsyekvch hielaseqtp
      541 erkssfiyem llalaspqdd iptpdeiekk nklketttrn yrgtc
//
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