GenomeNet

Database: RefSeq
Entry: NP_274656
LinkDB: NP_274656
Original site: NP_274656 
LOCUS       NP_274656                352 aa            linear   CON 03-AUG-2016
DEFINITION  alanine racemase [Neisseria meningitidis MC58].
ACCESSION   NP_274656
VERSION     NP_274656.1
DBLINK      BioProject: PRJNA57817
            Assembly: GCF_000008805.1
DBSOURCE    REFSEQ: accession NC_003112.2
KEYWORDS    RefSeq.
SOURCE      Neisseria meningitidis MC58
  ORGANISM  Neisseria meningitidis MC58
            Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (residues 1 to 352)
  AUTHORS   Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C.,
            Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Peden,J.F.,
            Dodson,R.J., Nelson,W.C., Gwinn,M.L., DeBoy,R., Peterson,J.D.,
            Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D.,
            Dougherty,B.A., Mason,T., Ciecko,A., Parksey,D.S., Blair,E.,
            Cittone,H., Clark,E.B., Cotton,M.D., Utterback,T.R., Khouri,H.,
            Qin,H., Vamathevan,J., Gill,J., Scarlato,V., Masignani,V.,
            Pizza,M., Grandi,G., Sun,L., Smith,H.O., Fraser,C.M., Moxon,E.R.,
            Rappuoli,R. and Venter,J.C.
  TITLE     Complete genome sequence of Neisseria meningitidis serogroup B
            strain MC58
  JOURNAL   Science 287 (5459), 1809-1815 (2000)
   PUBMED   10710307
REFERENCE   2  (residues 1 to 352)
  AUTHORS   Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C.,
            Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Ciecko,A.,
            Peden,J.F., Dodson,R.J., Nelson,W.C., Gwinn,M.L., Peterson,J.D.,
            Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D.,
            Dougherty,B.A., Mason,T.M., Parksey,D.S., Blair,E., Cittone,H.,
            Clark,E.B., Cotton,M.D., Utterback,T.R., Khouri,H.M., Qin,H.,
            Vamathevan,J., Gill,J., Scarlato,V., Masignani,V., DeBoy,R.T.,
            Pizza,M., Grandi,G., Sun,L., Smith,H.O., Fraser,C.M., Moxon,E.R.,
            Rappuoli,R. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2005) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Sequence update by submitter
REFERENCE   3  (residues 1 to 352)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (residues 1 to 352)
  AUTHORS   Tettelin,H., Saunders,N.J., Heidelberg,J., Jeffries,A.C.,
            Nelson,K.E., Eisen,J.A., Ketchum,K.A., Hood,D.W., Ciecko,A.,
            Peden,J.F., Dodson,R.J., Nelson,W.C., Gwinn,M.L., Peterson,J.D.,
            Hickey,E.K., Haft,D.H., Salzberg,S.L., White,O., Fleischmann,R.D.,
            Dougherty,B.A., Mason,T.M., Parksey,D.S., Blair,E., Cittone,H.,
            Clark,E.B., Cotton,M.D., Utterback,T.R., Khouri,H.M., Qin,H.,
            Vamathevan,J., Gill,J., Scarlato,V., Masignani,V., DeBoy,R.T.,
            Pizza,M., Grandi,G., Sun,L., Smith,H.O., Fraser,C.M., Moxon,E.R.,
            Rappuoli,R. and Venter,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2000) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AAF42000.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Neisseria meningitidis MC58"
                     /strain="MC58"
                     /db_xref="taxon:122586"
                     /serogroup="B"
     Protein         1..352
                     /product="alanine racemase"
                     /EC_number="5.1.1.1"
                     /calculated_mol_wt=38689
     Region          3..351
                     /region_name="PLPDE_III_AR_proteobact"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzymes, Proteobacterial Alanine Racemases; cd06827"
                     /db_xref="CDD:143500"
     Site            order(31,33,37,78,122,129,156,158,192..194,208..211,337)
                     /site_type="active"
                     /db_xref="CDD:143500"
     Site            order(31,33,37,78,158,192..193,208,210..211,337)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]"
                     /db_xref="CDD:143500"
     Site            order(33,37,129,158,337)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:143500"
     Site            order(33,250)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143500"
     Site            order(237,240,246..247,249..251,264,269,275,297,299,335,
                     337..338,343,345)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143500"
     CDS             1..352
                     /gene="alr"
                     /locus_tag="NMB1651"
                     /coded_by="NC_003112.2:1718540..1719598"
                     /note="identified by similarity to EGAD:154434; match to
                     protein family HMM PF00842; match to protein family HMM
                     PF01168; match to protein family HMM TIGR00492"
                     /transl_table=11
                     /db_xref="GeneID:903465"
CONTIG      join(WP_002224993.1:1..352)
ORIGIN      
        1 mrplnvqirl gnlrhnyril kemhggklla vvkadayghg avrcafalad ladgfavati
       61 degirlresg ithpivlleg vfeaseyeav eqyslwpavg nqwqlealli rhwkktvkvw
      121 lkmdsgmhrt gffphdyasa yaalkqseyv dsivkfshfs cadepesgmt eiqmeafdlg
      181 teglegeesl ansaailnvp earrdwgrag lalygispfg ggddrlkpvm rlstrifger
      241 vlqphspigy gatfytskst rvgliacgya dgyprrapsn spvavdgklt rvigrvsmdm
      301 mtieldasqe glghevelwg dtvnintvae aagtipyelm cnikrakfty ie
//
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