LOCUS NP_389083 650 aa linear CON 12-FEB-2021
DEFINITION phosphotransferase system (PTS) mannose-specific enzyme IIBCA
component [Bacillus subtilis subsp. subtilis str. 168].
ACCESSION NP_389083
VERSION NP_389083.2
DBLINK BioProject: PRJNA76
BioSample: SAMEA3138188
DBSOURCE REFSEQ: accession NC_000964.3
KEYWORDS RefSeq.
SOURCE Bacillus subtilis subsp. subtilis str. 168
ORGANISM Bacillus subtilis subsp. subtilis str. 168
Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE 1
AUTHORS Borriss,R., Danchin,A., Harwood,C.R., Medigue,C., Rocha,E.P.C.,
Sekowska,A. and Vallenet,D.
TITLE Bacillus subtilis, the model Gram-positive bacterium: 20 years of
annotation refinement
JOURNAL Microb Biotechnol 11 (1), 3-17 (2018)
PUBMED 29280348
REFERENCE 2 (residues 1 to 650)
AUTHORS Belda,E., Sekowska,A., Le Fevre,F., Morgat,A., Mornico,D.,
Ouzounis,C., Vallenet,D., Medigue,C. and Danchin,A.
TITLE An updated metabolic view of the Bacillus subtilis 168 genome
JOURNAL Microbiology (Reading, Engl.) 159 (Pt 4), 757-770 (2013)
PUBMED 23429746
REFERENCE 3 (residues 1 to 650)
AUTHORS Barbe,V., Cruveiller,S., Kunst,F., Lenoble,P., Meurice,G.,
Sekowska,A., Vallenet,D., Wang,T., Moszer,I., Medigue,C. and
Danchin,A.
TITLE From a consortium sequence to a unified sequence: the Bacillus
subtilis 168 reference genome a decade later
JOURNAL Microbiology (Reading, Engl.) 155 (Pt 6), 1758-1775 (2009)
PUBMED 19383706
REFERENCE 4 (residues 1 to 650)
AUTHORS Kunst,F., Ogasawara,N., Moszer,I., Albertini,A.M., Alloni,G.,
Azevedo,V., Bertero,M.G., Bessieres,P., Bolotin,A., Borchert,S.,
Borriss,R., Boursier,L., Brans,A., Braun,M., Brignell,S.C.,
Bron,S., Brouillet,S., Bruschi,C.V., Caldwell,B., Capuano,V.,
Carter,N.M., Choi,S.K., Cordani,J.J., Connerton,I.F.,
Cummings,N.J., Daniel,R.A., Denziot,F., Devine,K.M., Dusterhoft,A.,
Ehrlich,S.D., Emmerson,P.T., Entian,K.D., Errington,J., Fabret,C.,
Ferrari,E., Foulger,D., Fritz,C., Fujita,M., Fujita,Y., Fuma,S.,
Galizzi,A., Galleron,N., Ghim,S.Y., Glaser,P., Goffeau,A.,
Golightly,E.J., Grandi,G., Guiseppi,G., Guy,B.J., Haga,K.,
Haiech,J., Harwood,C.R., Henaut,A., Hilbert,H., Holsappel,S.,
Hosono,S., Hullo,M.F., Itaya,M., Jones,L., Joris,B., Karamata,D.,
Kasahara,Y., Klaerr-Blanchard,M., Klein,C., Kobayashi,Y.,
Koetter,P., Koningstein,G., Krogh,S., Kumano,M., Kurita,K.,
Lapidus,A., Lardinois,S., Lauber,J., Lazarevic,V., Lee,S.M.,
Levine,A., Liu,H., Masuda,S., Mauel,C., Medigue,C., Medina,N.,
Mellado,R.P., Mizuno,M., Moestl,D., Nakai,S., Noback,M., Noone,D.,
O'Reilly,M., Ogawa,K., Ogiwara,A., Oudega,B., Park,S.H., Parro,V.,
Pohl,T.M., Portelle,D., Porwollik,S., Prescott,A.M., Presecan,E.,
Pujic,P., Purnelle,B., Rapoport,G., Rey,M., Reynolds,S., Rieger,M.,
Rivolta,C., Rocha,E., Roche,B., Rose,M., Sadaie,Y., Sato,T.,
Scanlan,E., Schleich,S., Schroeter,R., Scoffone,F., Sekiguchi,J.,
Sekowska,A., Seror,S.J., Serror,P., Shin,B.S., Soldo,B.,
Sorokin,A., Tacconi,E., Takagi,T., Takahashi,H., Takemaru,K.,
Takeuchi,M., Tamakoshi,A., Tanaka,T., Terpstra,P., Togoni,A.,
Tosato,V., Uchiyama,S., Vandebol,M., Vannier,F., Vassarotti,A.,
Viari,A., Wambutt,R., Wedler,H., Weitzenegger,T., Winters,P.,
Wipat,A., Yamamoto,H., Yamane,K., Yasumoto,K., Yata,K., Yoshida,K.,
Yoshikawa,H.F., Zumstein,E., Yoshikawa,H. and Danchin,A.
TITLE The complete genome sequence of the gram-positive bacterium
Bacillus subtilis
JOURNAL Nature 390 (6657), 249-256 (1997)
PUBMED 9384377
REFERENCE 5 (residues 1 to 650)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2018) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 6 (residues 1 to 650)
AUTHORS Genoscope -,C.E.A.
CONSRTM AMAbiotics and Genoscope
TITLE Direct Submission
JOURNAL Submitted (24-JAN-2013) A. Danchin, AMAbiotics, Bldg G1, 2, rue
Gaston Cremieux, 91000 EVRY antoine.danchin@normalesup.org Bldg G1
Genoscope / CEA (Commissariat a l'energie atomique et aux energies
alternatives): BP 191 91006 EVRY cedex - FRANCE (E-mail:
seqref@genoscope.cns.fr - Web: www.genoscope.cns.fr)
REFERENCE 7 (residues 1 to 650)
AUTHORS Genoscope -,C.E.A.
CONSRTM Institut Pasteur and Genoscope
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2009) Genoscope - Centre National de Sequencage :
BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr
- Web : www.genoscope.cns.fr)
REFERENCE 8 (residues 1 to 650)
AUTHORS Kunst,F., Ogasawara,N., Yoshikawa,H. and Danchin,A.
TITLE Direct Submission
JOURNAL Submitted (18-NOV-1997) I. Moszer, A. Danchin, Genetique des
Genomes Bacteriens, Institut Pasteur, 28 rue du Docteur Roux, 75724
Paris Cedex 15, FRANCE. E-mail: moszer@pasteur.fr,
antoine.danchin@normalesup.org Phone: +33 (0)1 45 68 84 41, Fax:
+33 (0)1 45 68 89 48
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to CAB13058.
On Aug 12, 2009 this sequence version replaced NP_389083.1.
On or before Mar 17, 2009 this sequence version replaced
gi:32468687, gi:32468690, gi:32468695, gi:32468704, gi:32468715,
gi:32468723, gi:32468738, gi:32468743, gi:32468745, gi:32468758,
gi:32468767, gi:32468778, gi:32468787, gi:32468796, gi:32468802,
gi:32468809, gi:32468813, gi:32468825, gi:32468830, gi:32468833,
gi:32468840, gi:38680335.
Annotation results relative to BLAST similarities, COG
assignations, enzymatic function prediction (PRIAM software), TMHMM
and SignalP predictions, and synteny conservation (Syntonizer
software) are available in the MicroScope annotation platform
http://www.genoscope.cns.fr/agc/microscope.
The large cluster comprising the i, h and g rDNA regions could not
be properly resolved, we therefore incorporated the original
sequence of rRNAihg in the final assembly.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..650
/organism="Bacillus subtilis subsp. subtilis str. 168"
/strain="168"
/sub_species="subtilis"
/type_material="type strain of Bacillus subtilis"
/db_xref="taxon:224308"
Protein 1..650
/product="phosphotransferase system (PTS) mannose-specific
enzyme IIBCA component"
/EC_number="2.7.1.191"
/function="16.1: Circulate"
/function="16.11: Scavenge (Catabolism)"
/calculated_mol_wt=68895
Region 1..120
/region_name="FrwB"
/note="Phosphotransferase system fructose-specific
component IIB [Carbohydrate transport and metabolism];
COG1445"
/db_xref="CDD:224362"
Region 123..463
/region_name="FrwC"
/note="Phosphotransferase system, fructose-specific IIC
component [Carbohydrate transport and metabolism];
COG1299"
/db_xref="CDD:224218"
Region 501..650
/region_name="PtsN"
/note="Phosphotransferase system
mannitol/fructose-specific IIA domain (Ntr-type)
[Carbohydrate transport and metabolism, Signal
transduction mechanisms]; COG1762"
/db_xref="CDD:224676"
CDS 1..650
/gene="manP"
/locus_tag="BSU_12010"
/old_locus_tag="BSU12010"
/coded_by="NC_000964.3:1272725..1274677"
/experiment="publication(s) with functional evidences,
PMID:10627040, 10960106, 23551403"
/note="Evidence 1a: Function from experimental evidences
in the studied strain; PubMedId: 10627040, 10960106,
23551403; Product type t: transporter"
/transl_table=11
/db_xref="EnsemblGenomes-Gn:BSU12010"
/db_xref="EnsemblGenomes-Tr:CAB13058"
/db_xref="GOA:O31645"
/db_xref="InterPro:IPR002178"
/db_xref="InterPro:IPR003352"
/db_xref="InterPro:IPR003353"
/db_xref="InterPro:IPR003501"
/db_xref="InterPro:IPR004715"
/db_xref="InterPro:IPR006327"
/db_xref="InterPro:IPR013011"
/db_xref="InterPro:IPR013014"
/db_xref="InterPro:IPR016152"
/db_xref="InterPro:IPR036095"
/db_xref="PDB:2R48"
/db_xref="SubtiList:BG13176"
/db_xref="UniProtKB/Swiss-Prot:O31645"
/db_xref="GeneID:936437"
CONTIG join(WP_003245781.1:1..650)
ORIGIN
1 mkllaitscp ngiahtymaa enlqkaadrl gvsikvetqg gigvenklte eeireadaii
61 iaadrsvnkd rfigkkllsv gvqdgirkpe eliqkalngd ipvyrsatks esgnhqekkq
121 npiyrhlmng vsfmvpfivv gglliavalt lggektpkgl vipddsfwkt ieqigsasfs
181 fmipilagyi aysiadkpgl vpgmiggyia atgsfydsas gagflggiia gflagyaalw
241 ikklkvpkai qpimpiiiip vfaslivgla fvfligapva qifasltvwl agmkgsssil
301 lalilgamis fdmggpvnkv aflfgsamig egnyeimgpi avaicippig lgiatflgkr
361 kfeasqremg kaaftmglfg itegaipfaa qdplrvipsi magsmtgsvi amignvgdrv
421 ahggpivavl gavdhvlmff iaviagslvt alfvnvlkkd itaspvlset aptsapseaa
481 aaneikqpiq sqkaemsefk kltdiispel iepnlsgets ddiideliqk lsrrgallse
541 sgfkqailnr eqqgttaigm niaiphgkse avrepsvafg ikrsgvdwns ldgseaklif
601 miavpkesgg nqhlkilqml srklmddnyr erllsvqtte eayklleeie
//