LOCUS NP_462547 324 aa linear CON 08-SEP-2022
DEFINITION 2-keto-D-gluconate reductase [Salmonella enterica subsp. enterica
serovar Typhimurium str. LT2].
ACCESSION NP_462547
VERSION NP_462547.1
DBLINK BioProject: PRJNA57799
BioSample: SAMN02604315
DBSOURCE REFSEQ: accession NC_003197.2
KEYWORDS RefSeq.
SOURCE Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
ORGANISM Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
Enterobacteriaceae; Salmonella.
REFERENCE 1 (residues 1 to 324)
AUTHORS McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
TITLE Complete genome sequence of Salmonella enterica serovar Typhimurium
LT2
JOURNAL Nature 413 (6858), 852-856 (2001)
PUBMED 11677609
REFERENCE 2 (residues 1 to 324)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (08-SEP-2022) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (residues 1 to 324)
AUTHORS McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
SanMiguel,P. and Csonka,L.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-2016) Department of Microbiology and Molecular
Genetics, University of California, Irvine, CA 92697, USA
REMARK Sequence update by submitter
REFERENCE 4 (residues 1 to 324)
CONSRTM The Salmonella typhimurium Genome Sequencing Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2001) Genome Sequencing Center, Department of
Genetics, Washington University School of Medicine, 4444 Forest
Park Boulevard, St. Louis, MO 63108, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence is identical to AAL22506.
Supported by NIH grant 5U 01 AI43283
Coding sequences below are predicted from manually evaluated
computer analysis, using similarity information and the programs;
GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
GeneMark; http://opal.biology.gatech.edu/GeneMark/
EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
and Pedro Romero and Peter Karp at EcoCyc;
http://ecocyc.PangeaSystems.com/ecocyc/
The analyses of ribosome binding sites and promoter binding sites
were kindly provided by Heladia Salgado, Julio Collado-Vides and
ReguonDB;
http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
This sequence was finished as follows unless otherwise noted: all
regions were double stranded, sequenced with an alternate
chemistries or covered by high quality data (i.e., phred quality >=
30); an attempt was made to resolve all sequencing problems, such
as compressions and repeats; all regions were covered by sequence
from more than one m13 subclone.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..324
/organism="Salmonella enterica subsp. enterica serovar
Typhimurium str. LT2"
/strain="LT2"
/serovar="Typhimurium"
/sub_species="enterica"
/culture_collection="ATCC:700720"
/culture_collection="SGSC:1412"
/type_material="type strain of Salmonella enterica"
/db_xref="taxon:99287"
/focus
Protein 1..324
/product="2-keto-D-gluconate reductase"
/calculated_mol_wt=35124
Region 1..323
/region_name="PRK15409"
/note="glyoxylate/hydroxypyruvate reductase GhrB"
/db_xref="CDD:185307"
Site order(9..10,12,52..53,73,101..102,105..106,108..109,112,
116,118,126,128,130,133..139,140..144,162..163,167..168,
266..267,275,281..287,289..292,294)
/site_type="other"
/note="dimerization interface [polypeptide binding]"
/db_xref="CDD:240626"
Site order(52,74..76,99,237,285,288)
/site_type="other"
/note="ligand binding site [chemical binding]"
/db_xref="CDD:240626"
Site order(75..76,103,152..156,175..177,180,207..209,213..214,
235..237,261..262,285,287..288)
/site_type="other"
/note="NADP binding site [chemical binding]"
/db_xref="CDD:240626"
CDS 1..324
/gene="yiaE"
/locus_tag="STM3646"
/coded_by="NC_003197.2:3833699..3834673"
/note="similar to E. coli putative dehydrogenase
(AAC76577.1); Blastp hit to AAC76577.1 (328 aa), 83%
identity in aa 5 - 327"
/transl_table=11
/db_xref="GeneID:1255170"
CONTIG join(WP_000804674.1:1..324)
ORIGIN
1 mkpsiilykt lpddllhrle ahftvtqvpn lhpetvaqha qafasaqgll gasetvnral
61 lekmpalraa stisvgydnv evdaltarki vlmhtpavlt etvadtvmal mlatarrvvd
121 vaervkagew tesigpawfg vdvhhktlgi vgmgrigmal aqrahfgftm pvlyharrrh
181 qeaedrfnar ycdldtllqe adfvcvilpl taetrhlfga tqfarmkssa ifinagrgpv
241 vdenaliaal qngeiyaagl dvfeqeplsv dspllnmsnv vavphigsat hetrynmmac
301 avdnlidalq gkiekncvnp qaag
//
