GenomeNet

Database: RefSeq
Entry: NP_593968
LinkDB: NP_593968
Original site: NP_593968 
LOCUS       NP_593968                334 aa            linear   PLN 03-APR-2018
DEFINITION  putative glyoxylate reductase [Schizosaccharomyces pombe].
ACCESSION   NP_593968
VERSION     NP_593968.1
DBLINK      BioProject: PRJNA127
            BioSample: SAMEA3138176
DBSOURCE    REFSEQ: accession NM_001019395.2
KEYWORDS    RefSeq.
SOURCE      Schizosaccharomyces pombe (fission yeast)
  ORGANISM  Schizosaccharomyces pombe
            Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
            Schizosaccharomycetes; Schizosaccharomycetales;
            Schizosaccharomycetaceae; Schizosaccharomyces.
REFERENCE   1  (residues 1 to 334)
  AUTHORS   Wood,V., Gwilliam,R., Rajandream,M.A., Lyne,M., Lyne,R.,
            Stewart,A., Sgouros,J., Peat,N., Hayles,J., Baker,S., Basham,D.,
            Bowman,S., Brooks,K., Brown,D., Brown,S., Chillingworth,T.,
            Churcher,C., Collins,M., Connor,R., Cronin,A., Davis,P.,
            Feltwell,T., Fraser,A., Gentles,S., Goble,A., Hamlin,N., Harris,D.,
            Hidalgo,J., Hodgson,G., Holroyd,S., Hornsby,T., Howarth,S.,
            Huckle,E.J., Hunt,S., Jagels,K., James,K., Jones,L., Jones,M.,
            Leather,S., McDonald,S., McLean,J., Mooney,P., Moule,S.,
            Mungall,K., Murphy,L., Niblett,D., Odell,C., Oliver,K., O'Neil,S.,
            Pearson,D., Quail,M.A., Rabbinowitsch,E., Rutherford,K., Rutter,S.,
            Saunders,D., Seeger,K., Sharp,S., Skelton,J., Simmonds,M.,
            Squares,R., Squares,S., Stevens,K., Taylor,K., Taylor,R.G.,
            Tivey,A., Walsh,S., Warren,T., Whitehead,S., Woodward,J.,
            Volckaert,G., Aert,R., Robben,J., Grymonprez,B., Weltjens,I.,
            Vanstreels,E., Rieger,M., Schafer,M., Muller-Auer,S., Gabel,C.,
            Fuchs,M., Dusterhoft,A., Fritzc,C., Holzer,E., Moestl,D.,
            Hilbert,H., Borzym,K., Langer,I., Beck,A., Lehrach,H.,
            Reinhardt,R., Pohl,T.M., Eger,P., Zimmermann,W., Wedler,H.,
            Wambutt,R., Purnelle,B., Goffeau,A., Cadieu,E., Dreano,S.,
            Gloux,S., Lelaure,V., Mottier,S., Galibert,F., Aves,S.J., Xiang,Z.,
            Hunt,C., Moore,K., Hurst,S.M., Lucas,M., Rochet,M., Gaillardin,C.,
            Tallada,V.A., Garzon,A., Thode,G., Daga,R.R., Cruzado,L.,
            Jimenez,J., Sanchez,M., del Rey,F., Benito,J., Dominguez,A.,
            Revuelta,J.L., Moreno,S., Armstrong,J., Forsburg,S.L., Cerutti,L.,
            Lowe,T., McCombie,W.R., Paulsen,I., Potashkin,J., Shpakovski,G.V.,
            Ussery,D., Barrell,B.G. and Nurse,P.
  TITLE     The genome sequence of Schizosaccharomyces pombe
  JOURNAL   Nature 415 (6874), 871-880 (2002)
   PUBMED   11859360
  REMARK    Erratum:[Nature 2003 Jan 2;421(6918):94. Cerrutti L [corrected to
            Cerutti L]]
REFERENCE   2  (residues 1 to 334)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 334)
  AUTHORS   Wood,V.
  CONSRTM   The Schizosaccharomyces pombe Genome Sequencing Consortium
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2007) European Schizosaccharomyces genome
            sequencing project, Sanger Institute, The Wellcome Trust Genome
            Campus, Hinxton, Cambridge CB10 1SA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CAA20140.
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Schizosaccharomyces pombe"
                     /strain="972h-"
                     /db_xref="taxon:4896"
                     /chromosome="I"
     Protein         1..334
                     /product="putative glyoxylate reductase"
                     /calculated_mol_wt=36570
     Region          6..318
                     /region_name="Mand_dh_like"
                     /note="D-Mandelate Dehydrogenase-like dehydrogenases;
                     cd12168"
                     /db_xref="CDD:240645"
     Region          15..329
                     /region_name="LdhA"
                     /note="Lactate dehydrogenase or related 2-hydroxyacid
                     dehydrogenase [Energy production and conversion, Coenzyme
                     transport and metabolism, General function prediction
                     only]; COG1052"
                     /db_xref="CDD:223980"
     Site            order(60,88..90,113,246,293)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:240645"
     Site            order(115..116,119,123,126..127,130,132..133,142,144,
                     147..148,152..155,157,173..174,177..178,272,275..277,283,
                     285,288..295,298..300,302)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:240645"
     Site            order(117,164..167,186..187,216..220,223,244..246,270,293,
                     295..296)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:240645"
     Site            order(246,275,293)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:240645"
     CDS             1..334
                     /locus_tag="SPACUNK4.10"
                     /coded_by="NM_001019395.2:277..1281"
                     /db_xref="EnsemblGenomes-Gn:SPACUNK4.10"
                     /db_xref="EnsemblGenomes-Tr:SPACUNK4.10.1"
                     /db_xref="GeneID:2542594"
                     /db_xref="GOA:O14075"
                     /db_xref="InterPro:IPR006139"
                     /db_xref="InterPro:IPR006140"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR029752"
                     /db_xref="InterPro:IPR029753"
                     /db_xref="PomBase:SPACUNK4.10"
                     /db_xref="PomBase:SPACUNK4.10.1"
ORIGIN      
        1 mtlsgkpaal lvgtlkhahk ewealgkyae lktysdgtre dflakcktef qnvkaicrty
       61 nskfymgifd keiidnlpps vkfichlgag yetvdvaact argiqvshvp kavddatadv
      121 giflmlgalr gfnqgifelh knnwnanckp shdpegktlg ilglggigkt makrarafdm
      181 kivyhnrtpl peeeaegaef vsfddllaks dvlslnlpln ahtrhiigkp efqkmkrgiv
      241 ivntargavm deaalveald egivysagld vfeeepkihp gllenekvil lphlgtnsle
      301 tqykmecavl mnvkngivnd slpnlvpeqr gdie
//
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