GenomeNet

Database: RefSeq
Entry: NP_957204
LinkDB: NP_957204
Original site: NP_957204 
LOCUS       NP_957204                661 aa            linear   VRT 02-DEC-2018
DEFINITION  succinate dehydrogenase [ubiquinone] flavoprotein subunit,
            mitochondrial precursor [Danio rerio].
ACCESSION   NP_957204 XP_702394
VERSION     NP_957204.1
DBSOURCE    REFSEQ: accession NM_200910.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Danio.
REFERENCE   1  (residues 1 to 661)
  AUTHORS   Cheng ZX, Chu X, Wang SN, Peng XX and Li H.
  TITLE     Six genes of ompA family shuffling for development of polyvalent
            vaccines against Vibrio alginolyticus and Edwardsiella tarda
  JOURNAL   Fish Shellfish Immunol. 75, 308-315 (2018)
   PUBMED   29438846
REFERENCE   2  (residues 1 to 661)
  AUTHORS   Van Houcke J, Bollaerts I, Geeraerts E, Davis B, Beckers A, Van
            Hove I, Lemmens K, De Groef L and Moons L.
  TITLE     Successful optic nerve regeneration in the senescent zebrafish
            despite age-related decline of cell intrinsic and extrinsic
            response processes
  JOURNAL   Neurobiol. Aging 60, 1-10 (2017)
   PUBMED   28917662
REFERENCE   3  (residues 1 to 661)
  AUTHORS   Yang Y, Liu W, Li D, Qian L, Fu B and Wang C.
  TITLE     Altered glycometabolism in zebrafish exposed to thifluzamide
  JOURNAL   Chemosphere 183, 89-96 (2017)
   PUBMED   28535465
REFERENCE   4  (residues 1 to 661)
  AUTHORS   Yang YJ, Wang Y, Li Z, Zhou L and Gui JF.
  TITLE     Sequential, Divergent, and Cooperative Requirements of Foxl2a and
            Foxl2b in Ovary Development and Maintenance of Zebrafish
  JOURNAL   Genetics 205 (4), 1551-1572 (2017)
   PUBMED   28193729
REFERENCE   5  (residues 1 to 661)
  AUTHORS   Chen WC, Wang Z, Missinato MA, Park DW, Long DW, Liu HJ, Zeng X,
            Yates NA, Kim K and Wang Y.
  TITLE     Decellularized zebrafish cardiac extracellular matrix induces
            mammalian heart regeneration
  JOURNAL   Sci Adv 2 (11), e1600844 (2016)
   PUBMED   28138518
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 661)
  AUTHORS   Tang R, Dodd A, Lai D, McNabb WC and Love DR.
  TITLE     Validation of zebrafish (Danio rerio) reference genes for
            quantitative real-time RT-PCR normalization
  JOURNAL   Acta Biochim. Biophys. Sin. (Shanghai) 39 (5), 384-390 (2007)
   PUBMED   17492136
REFERENCE   7  (residues 1 to 661)
  AUTHORS   van der Meulen T, Schipper H, van den Boogaart JG, Huising MO,
            Kranenbarg S and van Leeuwen JL.
  TITLE     Endurance exercise differentially stimulates heart and axial muscle
            development in zebrafish (Danio rerio)
  JOURNAL   Am. J. Physiol. Regul. Integr. Comp. Physiol. 291 (4), R1040-R1048
            (2006)
   PUBMED   16966387
REFERENCE   8  (residues 1 to 661)
  AUTHORS   van der Meulen T, Schipper H, van Leeuwen JL and Kranenbarg S.
  TITLE     Effects of decreased muscle activity on developing axial
            musculature in nicb107 mutant zebrafish (Danio rerio)
  JOURNAL   J. Exp. Biol. 208 (Pt 19), 3675-3687 (2005)
   PUBMED   16169945
REFERENCE   9  (residues 1 to 661)
  AUTHORS   Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y,
            Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT and
            Chen Z.
  TITLE     Hematopoietic gene expression profile in zebrafish kidney marrow
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (46), 16240-16245 (2004)
   PUBMED   15520368
REFERENCE   10 (residues 1 to 661)
  AUTHORS   Miranda CL, Collodi P, Zhao X, Barnes DW and Buhler DR.
  TITLE     Regulation of cytochrome P450 expression in a novel liver cell line
            from zebrafish (Brachydanio rerio)
  JOURNAL   Arch. Biochem. Biophys. 305 (2), 320-327 (1993)
   PUBMED   8373170
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC045885.1.
            On Jul 6, 2005 this sequence version replaced XP_702394.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC045885.1, BC164560.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Danio rerio"
                     /strain="AB"
                     /db_xref="taxon:7955"
                     /chromosome="19"
                     /map="19"
     Protein         1..661
                     /product="succinate dehydrogenase [ubiquinone]
                     flavoprotein subunit, mitochondrial precursor"
                     /EC_number="1.3.5.1"
                     /note="succinate dehydrogenase [ubiquinone] flavoprotein
                     subunit, mitochondrial; fp; flavoprotein subunit of
                     complex II"
                     /calculated_mol_wt=67902
     transit_peptide 1..39
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Mitochondrion. {ECO:0000250|UniProtKB:Q0QF01};
                     propagated from UniProtKB/Swiss-Prot (Q7ZVF3.2)"
                     /calculated_mol_wt=4177
     mat_peptide     41..661
                     /product="Succinate dehydrogenase [ubiquinone]
                     flavoprotein subunit, mitochondrial"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7ZVF3.2)"
                     /calculated_mol_wt=67845
     Region          45..661
                     /region_name="PTZ00139"
                     /note="Succinate dehydrogenase [ubiquinone] flavoprotein
                     subunit; Provisional"
                     /db_xref="CDD:240286"
     Region          82..468
                     /region_name="NADB_Rossmann"
                     /note="Rossmann-fold NAD(P)(+)-binding proteins; cl21454"
                     /db_xref="CDD:304358"
     Site            96
                     /site_type="modified"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Tele-8alpha-FAD histidine.
                     {ECO:0000250|UniProtKB:Q9YHT1}; propagated from
                     UniProtKB/Swiss-Prot (Q7ZVF3.2)"
     Region          510..661
                     /region_name="Succ_DH_flav_C"
                     /note="Fumarate reductase flavoprotein C-term; pfam02910"
                     /db_xref="CDD:280980"
     CDS             1..661
                     /gene="sdha"
                     /gene_synonym="im:7141001; zgc:56051"
                     /coded_by="NM_200910.1:42..2027"
                     /db_xref="GeneID:393884"
                     /db_xref="ZFIN:ZDB-GENE-040426-874"
ORIGIN      
        1 maavcaasrv lgtkilssks lpavcqanrq lhfsiygkrg dakisdgvsn qypvvdhefd
       61 avvvgaggag lraafglsea gfntacvtkl fptrshtvaa qgginaalgn meqddwrwhf
      121 ydtvkgsdwl gdqdaihymt eqapaavvel enfgmpfsrt ddgkiyqraf ggqslkfgkg
      181 gqahrcccva drtghsllht lygrslrydt syfveyfald llmedgeckg vialcmedgs
      241 ihrfrakntv iatggygrtf fsctsahtst gdgnamvtra glpcqdlefv qfhptgiyga
      301 gclitegcrg eggilinseg erfmeryapn akdlasrdvv srsmtieire grgvgpdkdh
      361 vhlqlhhlpp qqlaarlpgi setamifagv dvtkepipvl ptvhynmggi ptnykgqvit
      421 ykdgqdhvvp glyacgeagc asvhganrlg anslldlvvf gracaltiae idtpgeklsp
      481 lkpnageasv anldkmryan gstrtseirl nmqktmqsha avfrtgdvlk egcvkmesvy
      541 ksmdniktfd rgivwntdlv etlelqnlml navqtivsae arkesrgaha redfkdrvde
      601 ydyskplqgq vkkpfeqhwr khtlsyvdpe tgkvtleyrp vidssldaed caaippairs
      661 y
//
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