LOCUS NP_957204 661 aa linear VRT 29-MAR-2025
DEFINITION succinate dehydrogenase [ubiquinone] flavoprotein subunit,
mitochondrial precursor [Danio rerio].
ACCESSION NP_957204 XP_702394
VERSION NP_957204.1
DBSOURCE REFSEQ: accession NM_200910.1
KEYWORDS RefSeq.
SOURCE Danio rerio (zebrafish)
ORGANISM Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE 1 (residues 1 to 661)
AUTHORS Zhang,Y., Liu,Y., Qin,W., Zheng,S., Xiao,J., Xia,X., Yuan,X.,
Zeng,J., Shi,Y., Zhang,Y., Ma,H., Varshney,G.K., Fei,J.F. and
Liu,Y.
TITLE Cytosine base editors with increased PAM and deaminase motif
flexibility for gene editing in zebrafish
JOURNAL Nat Commun 15 (1), 9526 (2024)
PUBMED 39496611
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 661)
AUTHORS Wang,J.X., Zhang,Y.Y., Qian,Y.C., Qian,Y.F., Jin,A.H., Wang,M.,
Luo,Y., Qiao,F., Zhang,M.L., Chen,L.Q. and Du,Z.Y.
TITLE Inhibition of mitochondrial citrate shuttle alleviates metabolic
syndromes induced by high-fat diet
JOURNAL Am J Physiol Cell Physiol 327 (3), C737-C749 (2024)
PUBMED 39069827
REFERENCE 3 (residues 1 to 661)
AUTHORS Wen,W., Guo,C., Chen,Z., Yang,D., Zhu,D., Jing,Q., Zheng,L., Sun,C.
and Tang,C.
TITLE Regular exercise attenuates alcoholic myopathy in zebrafish by
modulating mitochondrial homeostasis
JOURNAL PLoS One 18 (11), e0294700 (2023)
PUBMED 38032938
REMARK Publication Status: Online-Only
REFERENCE 4 (residues 1 to 661)
AUTHORS Zou,Y.Y., Tang,X.B., Chen,Z.L., Liu,B., Zheng,L., Song,M.Y.,
Xiao,Q., Zhou,Z.Q., Peng,X.Y. and Tang,C.F.
TITLE Exercise intervention improves mitochondrial quality in
non-alcoholic fatty liver disease zebrafish
JOURNAL Front Endocrinol (Lausanne) 14, 1162485 (2023)
PUBMED 37284220
REMARK Publication Status: Online-Only
REFERENCE 5 (residues 1 to 661)
AUTHORS Petel Legare,V., Rampal,C.J., Gurberg,T.J.N., Aaltonen,M.J.,
Janer,A., Zinman,L., Shoubridge,E.A. and Armstrong,G.A.B.
TITLE Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an
ALS-like phenotype and Complex I deficiency independent of the
mitochondrial integrated stress response
JOURNAL Dev Neurobiol 83 (1-2), 54-69 (2023)
PUBMED 36799027
REFERENCE 6 (residues 1 to 661)
AUTHORS Tang,R., Dodd,A., Lai,D., McNabb,W.C. and Love,D.R.
TITLE Validation of zebrafish (Danio rerio) reference genes for
quantitative real-time RT-PCR normalization
JOURNAL Acta Biochim Biophys Sin (Shanghai) 39 (5), 384-390 (2007)
PUBMED 17492136
REFERENCE 7 (residues 1 to 661)
AUTHORS van der Meulen,T., Schipper,H., van den Boogaart,J.G.,
Huising,M.O., Kranenbarg,S. and van Leeuwen,J.L.
TITLE Endurance exercise differentially stimulates heart and axial muscle
development in zebrafish (Danio rerio)
JOURNAL Am J Physiol Regul Integr Comp Physiol 291 (4), R1040-R1048 (2006)
PUBMED 16966387
REFERENCE 8 (residues 1 to 661)
AUTHORS van der Meulen,T., Schipper,H., van Leeuwen,J.L. and Kranenbarg,S.
TITLE Effects of decreased muscle activity on developing axial
musculature in nicb107 mutant zebrafish (Danio rerio)
JOURNAL J Exp Biol 208 (Pt 19), 3675-3687 (2005)
PUBMED 16169945
REFERENCE 9 (residues 1 to 661)
AUTHORS Song,H.D., Sun,X.J., Deng,M., Zhang,G.W., Zhou,Y., Wu,X.Y.,
Sheng,Y., Chen,Y., Ruan,Z., Jiang,C.L., Fan,H.Y., Zon,L.I.,
Kanki,J.P., Liu,T.X., Look,A.T. and Chen,Z.
TITLE Hematopoietic gene expression profile in zebrafish kidney marrow
JOURNAL Proc Natl Acad Sci U S A 101 (46), 16240-16245 (2004)
PUBMED 15520368
REFERENCE 10 (residues 1 to 661)
AUTHORS Miranda,C.L., Collodi,P., Zhao,X., Barnes,D.W. and Buhler,D.R.
TITLE Regulation of cytochrome P450 expression in a novel liver cell line
from zebrafish (Brachydanio rerio)
JOURNAL Arch Biochem Biophys 305 (2), 320-327 (1993)
PUBMED 8373170
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from BC045885.1.
On Jul 6, 2005 this sequence version replaced XP_702394.1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC045885.1, BC164560.1 [ECO:0000332]
RNAseq introns :: mixed sample support SAMEA3505370,
SAMEA3505371 [ECO:0006172]
##Evidence-Data-END##
##RefSeq-Attributes-START##
gene product(s) localized to mito. :: inferred from homology
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..661
/organism="Danio rerio"
/strain="AB"
/db_xref="taxon:7955"
/chromosome="19"
/map="19"
Protein 1..661
/product="succinate dehydrogenase [ubiquinone]
flavoprotein subunit, mitochondrial precursor"
/EC_number="1.3.5.1"
/note="succinate dehydrogenase [ubiquinone] flavoprotein
subunit, mitochondrial; fp; flavoprotein subunit of
complex II; malate dehydrogenase [quinone] flavoprotein
subunit"
/calculated_mol_wt=67902
transit_peptide 1..39
/note="Mitochondrion.
/evidence=ECO:0000250|UniProtKB:Q0QF01; propagated from
UniProtKB/Swiss-Prot (Q7ZVF3.2)"
/calculated_mol_wt=4177
mat_peptide 41..661
/product="Succinate dehydrogenase [ubiquinone]
flavoprotein subunit, mitochondrial. /id=PRO_0000344985"
/note="propagated from UniProtKB/Swiss-Prot (Q7ZVF3.2)"
/calculated_mol_wt=67845
Region 45..661
/region_name="PTZ00139"
/note="Succinate dehydrogenase [ubiquinone] flavoprotein
subunit; Provisional"
/db_xref="CDD:240286"
CDS 1..661
/gene="sdha"
/gene_synonym="im:7141001; zgc:56051"
/coded_by="NM_200910.1:42..2027"
/db_xref="GeneID:393884"
/db_xref="ZFIN:ZDB-GENE-040426-874"
ORIGIN
1 maavcaasrv lgtkilssks lpavcqanrq lhfsiygkrg dakisdgvsn qypvvdhefd
61 avvvgaggag lraafglsea gfntacvtkl fptrshtvaa qgginaalgn meqddwrwhf
121 ydtvkgsdwl gdqdaihymt eqapaavvel enfgmpfsrt ddgkiyqraf ggqslkfgkg
181 gqahrcccva drtghsllht lygrslrydt syfveyfald llmedgeckg vialcmedgs
241 ihrfrakntv iatggygrtf fsctsahtst gdgnamvtra glpcqdlefv qfhptgiyga
301 gclitegcrg eggilinseg erfmeryapn akdlasrdvv srsmtieire grgvgpdkdh
361 vhlqlhhlpp qqlaarlpgi setamifagv dvtkepipvl ptvhynmggi ptnykgqvit
421 ykdgqdhvvp glyacgeagc asvhganrlg anslldlvvf gracaltiae idtpgeklsp
481 lkpnageasv anldkmryan gstrtseirl nmqktmqsha avfrtgdvlk egcvkmesvy
541 ksmdniktfd rgivwntdlv etlelqnlml navqtivsae arkesrgaha redfkdrvde
601 ydyskplqgq vkkpfeqhwr khtlsyvdpe tgkvtleyrp vidssldaed caaippairs
661 y
//
