LOCUS       WP_000177947            1024 aa            linear   BCT 24-FEB-2020
DEFINITION  beta-galactosidase [Escherichia coli].
ACCESSION   WP_000177947
VERSION     WP_000177947.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 1024)
  AUTHORS   Juers,D.H., Heightman,T.D., Vasella,A., McCarter,J.D.,
            Mackenzie,L., Withers,S.G. and Matthews,B.W.
  TITLE     A structural view of the action of Escherichia coli (lacZ)
            beta-galactosidase
  JOURNAL   Biochemistry 40 (49), 14781-14794 (2001)
   PUBMED   11732897
REFERENCE   2  (residues 1 to 1024)
  AUTHORS   Juers,D.H., Jacobson,R.H., Wigley,D., Zhang,X.J., Huber,R.E.,
            Tronrud,D.E. and Matthews,B.W.
  TITLE     High resolution refinement of beta-galactosidase in a new crystal
            form reveals multiple metal-binding sites and provides a structural
            basis for alpha-complementation
  JOURNAL   Protein Sci. 9 (9), 1685-1699 (2000)
   PUBMED   11045615
REFERENCE   3  (residues 1 to 1024)
  AUTHORS   CRAVEN,G.R., STEERS,E. Jr. and ANFINSEN,C.B.
  TITLE     PURIFICATION, COMPOSITION, AND MOLECULAR WEIGHT OF THE
            BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12
  JOURNAL   J. Biol. Chem. 240, 2468-2477 (1965)
   PUBMED   14304855
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011221
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..1024
                     /gene="lacZ"
     Protein         1..1024
                     /product="beta-galactosidase"
                     /EC_number="3.2.1.23"
                     /calculated_mol_wt=116260
     Region          1..1024
                     /region_name="lacZ"
                     /note="beta-galactosidase; PRK09525"
                     /db_xref="CDD:236548"
ORIGIN      
        1 mtmitdslav vlqrrdwenp gvtqlnrlaa hppfaswrns eeartnrpsq qlrslngewq
       61 fvwfpapeav peswlecdlp dadtvvvpsn wqmhgydapi ytnvtypitv nppfvptenp
      121 tgcysltfnv deswlqegqt riifdgvnsa fhlwcngrwv gygqdsrlls efdlsaflra
      181 genrlavmvl rwsdgsyled qdmwrmsgif rdvsllhkpt tqisdfhvat lfnddfsrav
      241 leaevqmyge lrdelrvtvs lwqgetqvas gtapfggeii derggyadrv tlglnvenpk
      301 lwsaeipniy ravvelhtad gtlieaeacd vgfrevrien gllllngkpl lirgvnrheh
      361 hplhgqvmde qtmvqdillm kqnnfnavrc shypnhplwy tlcdryglyv vdeaniethg
      421 mvpmnrltdd prwlpamser vtrmvqrdrn hpsviiwslg nesghganhd alyrwiksvd
      481 psrpvqyegg gadtsatdii cpmyarvded qpfpavpkws ikkwlslpge mrplilceya
      541 hamgnslggf akywqafrqy prlqggfvwd lvdqslikyd engnpwsayg gdfgdtpndr
      601 qfcmnglvfa drtphpalte akhqqqffqf rlsgrtievt seylfhhsdn ellhwtvald
      661 gkplasgevp ldvapqgkqv ielpelprle stgqlwltvh vvqpnataws eaghisawqq
      721 wrlaenlsvt lpsaphaipq lttsetdfci eldnkrwqfn rqsgflsqmw igdkkqlltp
      781 lrdqftrapl dndigvseat ridpnawver wkaaghyqae aallqctadt ladavlittv
      841 hawqhqgktl fisrktyrid gsgqmaitvd vevasdtphp arigltcqla qvaervnwlg
      901 lgpqenypdr ltaacfdrwd lplsdmytpy vfpsenglrc gtrelnygph qwrgdfqfni
      961 srysqqqlme tshrhllhae egtwlnidgf hmgiggddsw spsvsaefql sagryhyqlv
     1021 wcqk
//