LOCUS WP_003413395 449 aa linear BCT 06-NOV-2024
DEFINITION MULTISPECIES: 4-aminobutyrate--2-oxoglutarate transaminase
[Mycobacterium].
ACCESSION WP_003413395
VERSION WP_003413395.1
KEYWORDS RefSeq.
SOURCE Mycobacterium
ORGANISM Mycobacterium
Bacteria; Bacillati; Actinomycetota; Actinomycetes;
Mycobacteriales; Mycobacteriaceae.
REFERENCE 1 (residues 1 to 449)
AUTHORS Bruce,H., Nguyen Tuan,A., Mangas Sanchez,J., Leese,C., Hopwood,J.,
Hyde,R., Hart,S., Turkenburg,J.P. and Grogan,G.
TITLE Structures of a gamma-aminobutyrate (GABA) transaminase from the
s-triazine-degrading organism Arthrobacter aurescens TC1 in complex
with PLP and with its external aldimine PLP-GABA adduct
JOURNAL Acta Crystallogr Sect F Struct Biol Cryst Commun 68 (Pt 10),
1175-1180 (2012)
PUBMED 23027742
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: HMM
Evidence Accession :: TIGR00700.1
Evidence Source :: JCVI
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..449
/organism="Mycobacterium"
/db_xref="taxon:1763"
gene 1..449
/gene="gabT"
Protein 1..449
/product="4-aminobutyrate--2-oxoglutarate transaminase"
/EC_number="2.6.1.19"
/GO_function="GO:0030170 - pyridoxal phosphate binding
[Evidence IEA]"
/GO_process="GO:0009448 - gamma-aminobutyric acid
metabolic process [Evidence IEA]"
/calculated_mol_wt=46682
Region 1..449
/region_name="PRK06058"
/note="4-aminobutyrate--2-oxoglutarate transaminase"
/db_xref="CDD:235685"
Site order(125..127,153..154,156,229,262,264..265,294)
/site_type="active"
/note="inhibitor-cofactor binding pocket [active]"
/db_xref="CDD:99735"
Site order(126..127,153..154,229,262,265,294)
/site_type="other"
/note="pyridoxal 5'-phosphate binding site [chemical
binding]"
/db_xref="CDD:99735"
Site 294
/site_type="active"
/note="catalytic residue [active]"
/db_xref="CDD:99735"
ORIGIN
1 maslqqsrrl vteipgpasq althrraaav ssgvgvtlpv fvaragggiv edvdgnrlid
61 lgsgiavtti gnssprvvda vrtqvaefth tcfmvtpyeg yvavaeqlnr itpgsgpkrs
121 vlfnsgaeav enavkiarsy tgkpavvafd hayhgrtnlt maltaksmpy ksgfgpfape
181 iyraplsypy rdglldkqla tngelaaara igvidkqvga nnlaalviep iqgeggfivp
241 aegflpalld wcrknhvvfi adevqtgfar tgamfacehe gpdglepdli ctakgiadgl
301 plsavtgrae imnaphvggl ggtfggnpva caaalatiat iesdgliera rqierlvtdr
361 lttlqavddr igdvrgrgam iavelvksgt tepdaglter lataahaagv iiltcgmfgn
421 iirllpplti gdellsegld ivcailadl
//