LOCUS       WP_004044270             307 aa            linear   BCT 29-MAR-2021
DEFINITION  sulfide-dependent adenosine diphosphate thiazole synthase
            [Haloferax volcanii].
ACCESSION   WP_004044270
VERSION     WP_004044270.1
KEYWORDS    RefSeq.
SOURCE      Haloferax volcanii
  ORGANISM  Haloferax volcanii
            Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria;
            Haloferacales; Haloferacaceae; Haloferax.
REFERENCE   1  (residues 1 to 307)
  AUTHORS   Zhang,X., Eser,B.E., Chanani,P.K., Begley,T.P. and Ealick,S.E.
  TITLE     Structural Basis for Iron-Mediated Sulfur Transfer in Archael and
            Yeast Thiazole Synthases
  JOURNAL   Biochemistry 55 (12), 1826-1838 (2016)
   PUBMED   26919468
REFERENCE   2  (residues 1 to 307)
  AUTHORS   Eser,B.E., Zhang,X., Chanani,P.K., Begley,T.P. and Ealick,S.E.
  TITLE     From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide
            Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis
  JOURNAL   J Am Chem Soc 138 (11), 3639-3642 (2016)
   PUBMED   26928142
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00292.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Haloferax volcanii"
                     /db_xref="taxon:2246"
     Protein         1..307
                     /product="sulfide-dependent adenosine diphosphate thiazole
                     synthase"
                     /EC_number="2.4.2.59"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=32293
     Region          2..291
                     /region_name="THI4"
                     /note="Archaeal ribulose 1,5-bisphosphate synthetase/yeast
                     thiazole synthase [Coenzyme transport and metabolism];
                     COG1635"
                     /db_xref="CDD:224550"
ORIGIN      
        1 msfdgftdat eaqvtraisd swmeefrert dtevivvggg psglvaakel aergvdvtiv
       61 eknnylgggf wlggflmnkv tvrdpaqrvl delgvpyees deaeglyvad gphacsalik
      121 aacdagakiq nmteftdvvl reddrvggiv mnwtpvhalp reltcvdpia vesdlvldat
      181 ghdavvlskl sergvldvng iehakehntg mdktadgeyg apghdspghd smwvseseds
      241 ivdatgvvhp gvvasgmava tahhlprmgp tfgamllsgr qaaqscldel grdapdvsis
      301 gpapadd
//