LOCUS       WP_007047423             268 aa            linear   BCT 14-JUN-2025
DEFINITION  MULTISPECIES: helix-turn-helix domain-containing protein
            [Clostridia].
ACCESSION   WP_007047423
VERSION     WP_007047423.1
KEYWORDS    RefSeq.
SOURCE      Clostridia
  ORGANISM  Clostridia
            Bacteria; Bacillati; Bacillota.
REFERENCE   1  (residues 1 to 268)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 268)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
REFERENCE   3  (residues 1 to 268)
  AUTHORS   Brennan,R.G. and Matthews,B.W.
  TITLE     The helix-turn-helix DNA binding motif
  JOURNAL   J Biol Chem 264 (4), 1903-1906 (1989)
   PUBMED   2644244
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10054599
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Clostridia"
                     /db_xref="taxon:186801"
     Protein         1..268
                     /product="helix-turn-helix domain-containing protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=30873
     Region          4..73
                     /region_name="HipB"
                     /note="Transcriptional regulator, contains XRE-family HTH
                     domain [Transcription]; COG1396"
                     /db_xref="CDD:441006"
     Region          <179..259
                     /region_name="DNA_ligase_A_N"
                     /note="DNA ligase N terminus; pfam04675"
                     /db_xref="CDD:461387"
ORIGIN      
        1 mkgatsiqer lwelrkdkgl nleelskltg isksalgsye kedfkeinhg nlitladfyg
       61 vsvdyllcrt enkeqintpl telhlndemv allksgrinn rllcelathk dfikfladie
      121 iyvdgiatmq iqnlnalvdt vrheiieryr pgeddphlkv lqaahisdde yfshmvlddl
      181 nliirdires hkkdsesapq ttvadelken leavenfkgs rleklamlyc kqlginyknl
      241 seeefrwlir ilqkskkmgt pisqrkkw
//