LOCUS       WP_011023758             805 aa            linear   BCT 29-JUN-2021
DEFINITION  CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
            [Methanosarcina acetivorans].
ACCESSION   WP_011023758
VERSION     WP_011023758.1
KEYWORDS    RefSeq.
SOURCE      Methanosarcina acetivorans
  ORGANISM  Methanosarcina acetivorans
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanosarcinales; Methanosarcinaceae; Methanosarcina.
REFERENCE   1  (residues 1 to 805)
  AUTHORS   Gencic,S., Duin,E.C. and Grahame,D.A.
  TITLE     Tight coupling of partial reactions in the acetyl-CoA
            decarbonylase/synthase (ACDS) multienzyme complex from
            Methanosarcina thermophila: acetyl C-C bond fragmentation at the a
            cluster promoted by protein conformational changes
  JOURNAL   J Biol Chem 285 (20), 15450-15463 (2010)
   PUBMED   20202935
REFERENCE   2  (residues 1 to 805)
  AUTHORS   Eggen,R.I., van Kranenburg,R., Vriesema,A.J., Geerling,A.C.,
            Verhagen,M.F., Hagen,W.R. and de Vos,W.M.
  TITLE     Carbon monoxide dehydrogenase from Methanosarcina frisia Go1.
            Characterization of the enzyme and the regulated expression of two
            operon-like cdh gene clusters
  JOURNAL   J Biol Chem 271 (24), 14256-14263 (1996)
   PUBMED   8662887
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00314.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Methanosarcina acetivorans"
                     /db_xref="taxon:2214"
     gene            1..805
                     /gene="cdhA"
     Protein         1..805
                     /product="CO dehydrogenase/acetyl-CoA synthase complex
                     subunit alpha"
                     /EC_number="1.2.7.4"
                     /GO_function="GO:0018492 - carbon-monoxide dehydrogenase
                     (acceptor) activity [Evidence IEA]"
                     /GO_process="GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=87824
     Region          1..801
                     /region_name="CdhA"
                     /note="CO dehydrogenase/acetyl-CoA synthase alpha subunit
                     [Energy production and conversion]; COG1152"
                     /db_xref="CDD:224074"
ORIGIN      
        1 msklttgsfs iedlesvqit innivgaake aaeekakelg pmgptamagl asyrswnlll
       61 ldryepvltp mcdqccycty gpcdlsgnkr gacgidmagq tgrefflrvi tgtachaahg
      121 rhlldhviev fgedlplnlg esnvltpnvt ictglspktl gecrapmeyv eeqltqllat
      181 ihagqesaei dydskalfsg sldhvgmevs diaqvsaydf pkadpeapli eigmgsidks
      241 kplivaighn vagvtyimdy meennltdkm eiaglcctaf dmtrykeadr rapyakivgs
      301 lakelkvirs gmpdvivvde qcvrgdvlse sqklkipvia snekimmglp drtdadvdsi
      361 veeiksgaip gcvmldydkl gelipkiaev mapirdaegi taiptdeefk vyidkcvkcg
      421 ecmlacpeel dipealeyaa kgsyeyleal hdvcigcrrc eqvckkeipi lnvlekaaqk
      481 siseekgwvr sgrgqasdae irkeglnlvm gttpgiiaii gcpnypagtk dvyliaeefl
      541 krnyllavsg csamdigmfk dedgktlyek ypgtfagggl lntgscvsna hisgaaekva
      601 gifaqrtlag nlaeiadytl nrvgacglaw gaysqkaasi gtgcniygip avlgphssky
      661 rraliaknyd eskwkvydgr dgsemtippa pefllttaet wqeaipmmak acirpsdnnm
      721 grsiklthwm elskkylgve pedwwkfvrn eadlplakre ellkrleaeh gweidwkrkk
      781 iisgpkikfd vsaqptnlkr lckea
//