LOCUS       WP_012395684             441 aa            linear   BCT 27-MAR-2023
DEFINITION  MULTISPECIES: homoserine dehydrogenase [Mycobacterium].
ACCESSION   WP_012395684
VERSION     WP_012395684.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium
  ORGANISM  Mycobacterium
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae.
REFERENCE   1  (residues 1 to 441)
  AUTHORS   Navratna,V., Reddy,G. and Gopal,B.
  TITLE     Structural basis for the catalytic mechanism of homoserine
            dehydrogenase
  JOURNAL   Acta Crystallogr D Biol Crystallogr 71 (Pt 5), 1216-1225 (2015)
   PUBMED   25945586
REFERENCE   2  (residues 1 to 441)
  AUTHORS   Thomas,D., Barbey,R. and Surdin-Kerjan,Y.
  TITLE     Evolutionary relationships between yeast and bacterial homoserine
            dehydrogenases
  JOURNAL   FEBS Lett 323 (3), 289-293 (1993)
   PUBMED   8500624
REFERENCE   3  (residues 1 to 441)
  AUTHORS   Parsot,C.
  TITLE     Evolution of biosynthetic pathways: a common ancestor for threonine
            synthase, threonine dehydratase and D-serine dehydratase
  JOURNAL   EMBO J 5 (11), 3013-3019 (1986)
   PUBMED   3098560
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11482218
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Mycobacterium"
                     /db_xref="taxon:1763"
     Protein         1..441
                     /product="homoserine dehydrogenase"
                     /EC_number="1.1.1.3"
                     /GO_function="GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=45610
     Region          6..437
                     /region_name="PRK06349"
                     /note="homoserine dehydrogenase; Provisional"
                     /db_xref="CDD:235783"
ORIGIN      
        1 msgdvkpvgv avlglgnvgs evvriieesa ddlaarvgap lvlrgvgvrr vaddrgvpid
       61 lltddieklv sredvdivve vmgpvepsrk ailtalehgk svvtankall ststgelaqa
      121 aesahvdlyf eaavagaipv irpltqslag dtvlrvagiv ngttnyilse mdstgadyak
      181 aladagalgy aeadptadve gfdaaakaai lasiafhtrv taddvyregi tkitpadfas
      241 aralgctikl lsicerlttd egqqrvsarv ypalvplshp latvngafna vvveaeaagr
      301 lmfygqgagg aptasavtgd lvmaarnrvl gsrgpresky aqlpvapmgf istryyvsmn
      361 vadkagvlsa vaaefakrdv siaevrqegv vdqdgqriga rivvvthlat daalsetvea
      421 ladldvvenv asvlrlegnd l
//