LOCUS       WP_013399386             907 aa            linear   BCT 29-MAR-2023
DEFINITION  sialidase family protein [Gardnerella vaginalis].
ACCESSION   WP_013399386
VERSION     WP_013399386.1
KEYWORDS    RefSeq.
SOURCE      Gardnerella vaginalis
  ORGANISM  Gardnerella vaginalis
            Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
            Bifidobacteriaceae; Gardnerella.
REFERENCE   1  (residues 1 to 907)
  AUTHORS   Taylor,G.
  TITLE     Sialidases: structures, biological significance and therapeutic
            potential
  JOURNAL   Curr Opin Struct Biol 6 (6), 830-837 (1996)
   PUBMED   8994884
REFERENCE   2  (residues 1 to 907)
  AUTHORS   Roggentin,P., Schauer,R., Hoyer,L.L. and Vimr,E.R.
  TITLE     The sialidase superfamily and its spread by horizontal gene
            transfer
  JOURNAL   Mol Microbiol 9 (5), 915-921 (1993)
   PUBMED   7934919
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10202570
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Gardnerella vaginalis"
                     /db_xref="taxon:2702"
     Protein         1..907
                     /product="sialidase family protein"
                     /EC_number="3.2.1.-"
                     /calculated_mol_wt=99625
     Region          391..844
                     /region_name="Sialidase_non-viral"
                     /note="Non-viral sialidases; cd15482"
                     /db_xref="CDD:271234"
     Region          404..456
                     /region_name="Sialidase propeller 1"
                     /note="Sialidase propeller 1 [structural motif]"
                     /db_xref="CDD:271234"
     Site            order(405,430,713,729,793,821,837)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:271234"
     Region          470..622
                     /region_name="Sialidase propeller 2"
                     /note="Sialidase propeller 2 [structural motif]"
                     /db_xref="CDD:271234"
     Region          633..687
                     /region_name="Sialidase propeller 3"
                     /note="Sialidase propeller 3 [structural motif]"
                     /db_xref="CDD:271234"
     Region          712..752
                     /region_name="Sialidase propeller 4"
                     /note="Sialidase propeller 4 [structural motif]"
                     /db_xref="CDD:271234"
     Region          762..814
                     /region_name="Sialidase propeller 5"
                     /note="Sialidase propeller 5 [structural motif]"
                     /db_xref="CDD:271234"
ORIGIN      
        1 merrstktts liediadikg sehtrfnhat ikitpsseik kysenesgin rkdkneeinq
       61 negiigfkfv ansdcdlldi kpaqkseasa qqehttpiik isikedapll saqnlledsa
      121 dangakeial qmedalgacd grehdfaity gsfgsrfyld gyqcfasatn lgpqrvsgka
      181 aevcaaqaes sqiydfyyss hlpnpeeian satqaqpdiw fagpticard ikrvscnssg
      241 tlhiqfrlrg pgqhgvlfaa gtvgtktnle ssekisvyag pegikitlid setciksvie
      301 aaasvddgew hdliiranrg aidiyvdgys eshnigqfwf anipelnavs igedlrgvrl
      361 mgeartggiy fsaltegqiq risrvkplvt talfdtgyag srsyripslv ktrmgtliag
      421 adqrtsvsnd apnhinfvir rstdggktwk plqtvinmpg knlgklgasa idscpildpa
      481 gkserinvli dlnpsgiglt ncktdvgvde cgrikmedrf grhyaalmdg saavklpcds
      541 sekecatkwl vfpdgsiknc dshndlrnns hsnqtcdsst wniwksqeia sesqplfaek
      601 tcyiaqiysd ddgktwsatr lidhmvkepw msfagvcpgn givirqsekh ygrilvpfyc
      661 sgkskshyss galisdddgk twsrgkmine grlingkivd patmqdddat ssetvfverk
      721 ngdilaffrn qnrsgcvgka ishdcgetws elifdtslpe ifsqpsatcf nsenadnadc
      781 iafanasqmm pyrgrgvvrf sydggktwak svcinpfhhv yqclsssnkr tlqllweret
      841 tgiyitaids nlwkqdnlqi dfksnaksln ntdldciknk intsekmkdl eegsltrter
      901 sqhgrdi
//