LOCUS       WP_023438619             434 aa            linear   BCT 10-OCT-2019
DEFINITION  phosphoenolpyruvate mutase [Clostridium tetani].
ACCESSION   WP_023438619
VERSION     WP_023438619.1
KEYWORDS    RefSeq.
SOURCE      Clostridium tetani
  ORGANISM  Clostridium tetani
            Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (residues 1 to 434)
  AUTHORS   Sarkar,M., Hamilton,C.J. and Fairlamb,A.H.
  TITLE     Properties of phosphoenolpyruvate mutase, the first enzyme in the
            aminoethylphosphonate biosynthetic pathway in Trypanosoma cruzi
  JOURNAL   J. Biol. Chem. 278 (25), 22703-22708 (2003)
   PUBMED   12672809
REFERENCE   2  (residues 1 to 434)
  AUTHORS   Coyne,M.J., Kalka-Moll,W., Tzianabos,A.O., Kasper,D.L. and
            Comstock,L.E.
  TITLE     Bacteroides fragilis NCTC9343 produces at least three distinct
            capsular polysaccharides: cloning, characterization, and
            reassignment of polysaccharide B and C biosynthesis loci
  JOURNAL   Infect. Immun. 68 (11), 6176-6181 (2000)
   PUBMED   11035722
REFERENCE   3  (residues 1 to 434)
  AUTHORS   Schwartz,D., Recktenwald,J., Pelzer,S. and Wohlleben,W.
  TITLE     Isolation and characterization of the PEP-phosphomutase and the
            phosphonopyruvate decarboxylase genes from the phosphinothricin
            tripeptide producer Streptomyces viridochromogenes Tu494
  JOURNAL   FEMS Microbiol. Lett. 163 (2), 149-157 (1998)
   PUBMED   9673017
REFERENCE   4  (residues 1 to 434)
  AUTHORS   Hidaka,T., Hidaka,M. and Seto,H.
  TITLE     Studies on the biosynthesis of bialaphos (SF-1293). 14. Nucleotide
            sequence of phosphoenolpyruvate phosphomutase gene isolated from a
            bialaphos producing organism, Streptomyces hygroscopicus, and its
            expression in Streptomyces lividans
  JOURNAL   J. Antibiot. 45 (12), 1977-1980 (1992)
   PUBMED   1337066
REFERENCE   5  (residues 1 to 434)
  AUTHORS   Seidel,H.M., Pompliano,D.L. and Knowles,J.R.
  TITLE     Phosphonate biosynthesis: molecular cloning of the gene for
            phosphoenolpyruvate mutase from Tetrahymena pyriformis and
            overexpression of the gene product in Escherichia coli
  JOURNAL   Biochemistry 31 (9), 2598-2608 (1992)
   PUBMED   1547241
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02320.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Clostridium tetani"
                     /db_xref="taxon:1513"
     gene            1..434
                     /gene="aepX"
     Protein         1..434
                     /product="phosphoenolpyruvate mutase"
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=49222
     Region          6..142
                     /region_name="cytidylyltransferase"
                     /note="cd02170"
                     /db_xref="CDD:173921"
     Site            order(12..15,19,21..22,25,40,44,48,75,81,94..95,97,111,
                     126..127,130)
                     /site_type="active"
                     /db_xref="CDD:173921"
     Region          153..434
                     /region_name="PEP_mutase"
                     /note="phosphoenolpyruvate mutase; TIGR02320"
                     /db_xref="CDD:274077"
ORIGIN      
        1 mnnkvtksvy acfstgvihe ghmkiineak kygdvivgvl sdeacvkfdr fpttqiedrv
       61 emferllevn kvviqkttsy rdvlnelkpd yvihgdnwks gpqsvirqev iemlkgwngq
      121 lieipytrnt nvkkvdditr eklampeyrr krlrqllklr pivkaievhn gitgliaekt
      181 vverngeldq fdamwisslc dstakgkpdi elvdmssrld tvndvmevtt kpiildgdtg
      241 glvehfvynv rtlermgvsa viiedktglk knslfgtevq qnqdtvenfc hkiseakeal
      301 rtdefmiiar ieslileqgm edalnrayay vnagadgimi hsrkkdptei fefcdkfrkt
      361 dkdtpivvvp tsfntvteee fithgvnivi yanqltrsaf pamqqtatki lechrakevd
      421 dnlmsikdii tlid
//