LOCUS       WP_031039417             259 aa            linear   BCT 13-DEC-2021
DEFINITION  MULTISPECIES: exodeoxyribonuclease III [Streptomyces].
ACCESSION   WP_031039417
VERSION     WP_031039417.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces
  ORGANISM  Streptomyces
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae.
REFERENCE   1  (residues 1 to 259)
  AUTHORS   Mathieu,A., O'Rourke,E.J. and Radicella,J.P.
  TITLE     Helicobacter pylori genes involved in avoidance of mutations
            induced by 8-oxoguanine
  JOURNAL   J Bacteriol 188 (21), 7464-7469 (2006)
   PUBMED   16936028
REFERENCE   2  (residues 1 to 259)
  AUTHORS   Georg,J., Schomacher,L., Chong,J.P., Majernik,A.I., Raabe,M.,
            Urlaub,H., Muller,S., Ciirdaeva,E., Kramer,W. and Fritz,H.J.
  TITLE     The Methanothermobacter thermautotrophicus ExoIII homologue Mth212
            is a DNA uridine endonuclease
  JOURNAL   Nucleic Acids Res 34 (18), 5325-5336 (2006)
   PUBMED   17012282
REFERENCE   3  (residues 1 to 259)
  AUTHORS   Shida,T., Ogawa,T., Ogasawara,N. and Sekiguchi,J.
  TITLE     Characterization of Bacillus subtilis ExoA protein: a
            multifunctional DNA-repair enzyme similar to the Escherichia coli
            exonuclease III
  JOURNAL   Biosci Biotechnol Biochem 63 (9), 1528-1534 (1999)
   PUBMED   10540738
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00633.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Streptomyces"
                     /db_xref="taxon:1883"
     Protein         1..259
                     /product="exodeoxyribonuclease III"
                     /calculated_mol_wt=28211
     Region          1..257
                     /region_name="ExoIII-like_AP-endo"
                     /note="Escherichia coli exonuclease III (ExoIII) and
                     Neisseria meningitides NExo-like subfamily of the ExoIII
                     family purinic/apyrimidinic (AP) endonucleases; cd09086"
                     /db_xref="CDD:197320"
     Site            order(7,34,108,111,149,151,250)
                     /site_type="other"
                     /note="putative phosphate binding site [ion binding]"
                     /db_xref="CDD:197320"
     Site            order(7,34,108,149,151,220,249..250)
                     /site_type="active"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197320"
     Site            order(9..10,12..14,34,60..61,108,111,113,119,149,151,203,
                     206..207,217,219..220,246..247,250)
                     /site_type="active"
                     /db_xref="CDD:197320"
     Site            order(9,34,249..250)
                     /site_type="metal-binding"
                     /note="metal binding site A [ion binding]"
                     /db_xref="CDD:197320"
     Site            order(9..10,12..14,60..61,108,111,113,119,206..207,
                     246..247)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:197320"
     Site            order(108,111,149,151,203,217,219,250)
                     /site_type="other"
                     /note="putative AP binding site [nucleotide binding]"
                     /db_xref="CDD:197320"
     Site            order(108,149,151,250)
                     /site_type="other"
                     /note="putative metal binding site B [ion binding]"
                     /db_xref="CDD:197320"
ORIGIN      
        1 mriatwnvns itarlprlla wlestgtdvl clqeakvaee qfpfdqlrea gyeaavhatg
       61 rwngvavisr vgledvvkgl pgdpgydgap epraisatcg parvwsvyvp ngrevdhphy
      121 ayklqwfeal kaavagdaag srpfavlgdy nvaptdddvf dvaafeglth vtpaeraala
      181 alreaglsdv vprplkydhp ftywdyrqlg fpknrgmrid lvygnesfak avtdayvdre
      241 erkgkgasdh apvvvdldv
//