LOCUS WP_068554889 215 aa linear BCT 17-FEB-2025
DEFINITION helix-turn-helix transcriptional regulator [Thermotalea
metallivorans].
ACCESSION WP_068554889
VERSION WP_068554889.1
KEYWORDS RefSeq.
SOURCE Thermotalea metallivorans
ORGANISM Thermotalea metallivorans
Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
Thermotaleaceae; Thermotalea.
REFERENCE 1 (residues 1 to 215)
AUTHORS Stuffle,E.C., Johnson,M.S. and Watts,K.J.
TITLE PAS domains in bacterial signal transduction
JOURNAL Curr Opin Microbiol 61, 8-15 (2021)
PUBMED 33647528
REFERENCE 2 (residues 1 to 215)
AUTHORS Henry,J.T. and Crosson,S.
TITLE Ligand-binding PAS domains in a genomic, cellular, and structural
context
JOURNAL Annu Rev Microbiol 65, 261-286 (2011)
PUBMED 21663441
REFERENCE 3 (residues 1 to 215)
AUTHORS Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
TITLE The many faces of the helix-turn-helix domain: transcription
regulation and beyond
JOURNAL FEMS Microbiol Rev 29 (2), 231-262 (2005)
PUBMED 15808743
REFERENCE 4 (residues 1 to 215)
AUTHORS Hefti,M.H., Francoijs,K.J., de Vries,S.C., Dixon,R. and Vervoort,J.
TITLE The PAS fold. A redefinition of the PAS domain based upon
structural prediction
JOURNAL Eur J Biochem 271 (6), 1198-1208 (2004)
PUBMED 15009198
REFERENCE 5 (residues 1 to 215)
AUTHORS Rosinski,J.A. and Atchley,W.R.
TITLE Molecular evolution of helix-turn-helix proteins
JOURNAL J Mol Evol 49 (3), 301-309 (1999)
PUBMED 10473770
REFERENCE 6 (residues 1 to 215)
AUTHORS Taylor,B.L. and Zhulin,I.B.
TITLE PAS domains: internal sensors of oxygen, redox potential, and light
JOURNAL Microbiol Mol Biol Rev 63 (2), 479-506 (1999)
PUBMED 10357859
REFERENCE 7 (residues 1 to 215)
AUTHORS Ponting,C.P. and Aravind,L.
TITLE PAS: a multifunctional domain family comes to light
JOURNAL Curr Biol 7 (11), R674-R677 (1997)
PUBMED 9382818
REFERENCE 8 (residues 1 to 215)
AUTHORS Wintjens,R. and Rooman,M.
TITLE Structural classification of HTH DNA-binding domains and
protein-DNA interaction modes
JOURNAL J Mol Biol 262 (2), 294-313 (1996)
PUBMED 8831795
REFERENCE 9 (residues 1 to 215)
AUTHORS Brennan,R.G. and Matthews,B.W.
TITLE The helix-turn-helix DNA binding motif
JOURNAL J Biol Chem 264 (4), 1903-1906 (1989)
PUBMED 2644244
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: Conserved Domain (CDD)
Evidence Accession :: Domain architecture ID 11459460
Evidence Source :: NCBI SPARCLE
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..215
/organism="Thermotalea metallivorans"
/db_xref="taxon:520762"
Protein 1..215
/product="helix-turn-helix transcriptional regulator"
/GO_function="GO:0003677 - DNA binding [Evidence IEA]"
/GO_function="GO:0003700 - DNA-binding transcription
factor activity [Evidence IEA]"
/GO_function="GO:0005515 - protein binding [Evidence IEA]"
/GO_function="GO:0140110 - transcription regulator
activity [Evidence IEA]"
/GO_process="GO:0006355 - regulation of DNA-templated
transcription [Evidence IEA]"
/GO_process="GO:0007165 - signal transduction [Evidence
IEA]"
/calculated_mol_wt=23751
Region 1..212
/region_name="YheO"
/note="Predicted transcriptional regulator YheO, contains
PAS and DNA-binding HTH domains [Transcription]; COG2964"
/db_xref="CDD:442204"
ORIGIN
1 msneihpilk smipivegia ktfgkncevv lhdfknfqss iiaienghvt grslgspmte
61 vglqairkgn tndniinytg kstdgralks stmfikdene hvigclcinf dmselivaqn
121 aiqeltqtes kedvkqndyl tnsvndvlss ivsntleelg kpvaymskde kvnivkkldd
181 qgaflikgai dyvakvlcvs rytiynylde irvnk
//