LOCUS       WP_073920157             462 aa            linear   BCT 24-DEC-2024
DEFINITION  helix-turn-helix domain-containing protein [Streptomyces sp.
            CB00455].
ACCESSION   WP_073920157
VERSION     WP_073920157.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CB00455
  ORGANISM  Streptomyces sp. CB00455
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (residues 1 to 462)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 462)
  AUTHORS   Aravind,L. and Koonin,E.V.
  TITLE     DNA-binding proteins and evolution of transcription regulation in
            the archaea
  JOURNAL   Nucleic Acids Res 27 (23), 4658-4670 (1999)
   PUBMED   10556324
REFERENCE   3  (residues 1 to 462)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 18528417
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Streptomyces sp. CB00455"
                     /db_xref="taxon:1703927"
     Protein         1..462
                     /product="helix-turn-helix domain-containing protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=48952
     Region          5..81
                     /region_name="HipB"
                     /note="Transcriptional regulator, contains XRE-family HTH
                     domain [Transcription]; COG1396"
                     /db_xref="CDD:441006"
     Region          52..>285
                     /region_name="Spy"
                     /note="Predicted O-linked N-acetylglucosamine transferase,
                     SPINDLY family [Posttranslational modification, protein
                     turnover, chaperones]; COG3914"
                     /db_xref="CDD:443119"
     Region          214..>427
                     /region_name="Spy"
                     /note="Predicted O-linked N-acetylglucosamine transferase,
                     SPINDLY family [Posttranslational modification, protein
                     turnover, chaperones]; COG3914"
                     /db_xref="CDD:443119"
     Region          320..348
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(321,324..325,328..329,331,360,363..364,367..368,
                     370..371,400,403..404,407..408,411)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          358..394
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          399..427
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
ORIGIN      
        1 maesqtlgsr irrlrreagl sqmdlagdnl spsyisllea gkrtpspevl eqiaarlgca
       61 peqllellap erhdtlqtdl ryaeislrng dpktaldtyt avrdkaaaag qdgirlsaey
      121 gvaqalehgg rleeaadryq alldhagygq sliprlavav alcrcyretg dlahaidlan
      181 atleearalr ltptvlgvel latlvglyce rgdlhraaal artaieeaeg iddrkalgaa
      241 ywnagvvahr ggasadalll leralaiyse gddaralsrl rnayasvlmq sesgdiaeak
      301 sqlvrsaetl adhgstvdma ycetalarac llesdprqae qharralell gsghrletar
      361 tllvlagaql qlgddaaaea gceraallle aseadrqaas awndlgelle rsgrteravw
      421 afrqslrclg qrssllpaag gqaaagsaag raraagpadr gr
//