LOCUS       XP_003144317            1028 aa            linear   INV 13-MAR-2017
DEFINITION  angiotensin-converting enzyme family protein [Loa loa].
ACCESSION   XP_003144317
VERSION     XP_003144317.1
DBLINK      BioProject: PRJNA60051
            BioSample: SAMN00103043
DBSOURCE    REFSEQ: accession XM_003144269.1
KEYWORDS    RefSeq.
SOURCE      Loa loa (African eye worm)
  ORGANISM  Loa loa
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
REFERENCE   1  (residues 1 to 1028)
  AUTHORS   Nutman,T.B., Fink,D.L., Russ,C., Young,S., Zeng,Q., Gargeya,S.,
            Alvarado,L., Berlin,A., Chapman,S.B., Chen,Z., Freedman,E.,
            Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R.,
            Heiman,D., Howarth,C., Mehta,T., Neiman,D., Pearson,M., Roberts,A.,
            Saif,S., Shea,T., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.,
            White,J., Yandava,C., Haas,B., Henn,M.R., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Loa loa
  JOURNAL   Unpublished
REFERENCE   2  (residues 1 to 1028)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2017) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 1028)
  AUTHORS   Nutman,T.B., Fink,D.L., Russ,C., Young,S., Zeng,Q., Gargeya,S.,
            Alvarado,L., Berlin,A., Chapman,S.B., Chen,Z., Freedman,E.,
            Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R.,
            Heiman,D., Howarth,C., Mehta,T., Neiman,D., Pearson,M., Roberts,A.,
            Saif,S., Shea,T., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.,
            White,J., Yandava,C., Haas,B., Henn,M.R., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2012) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to EFO19754.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Loa loa"
                     /db_xref="taxon:7209"
                     /chromosome="Unknown"
     Protein         1..1028
                     /product="angiotensin-converting enzyme family protein"
                     /calculated_mol_wt=115514
     Region          280..856
                     /region_name="M2_ACE"
                     /note="Peptidase family M2, angiotensin converting enzyme
                     (ACE); cd06461"
                     /db_xref="CDD:341055"
     Site            order(602,604..606,627,633..634,637,641,660..661,665,708,
                     762..764,770,772,775)
                     /site_type="active"
                     /db_xref="CDD:341055"
     Region          <900..928
                     /region_name="EB"
                     /note="EB module; pfam01683"
                     /db_xref="CDD:426381"
     CDS             1..1028
                     /locus_tag="LOAG_08740"
                     /coded_by="XM_003144269.1:1..3087"
                     /db_xref="GeneID:9946166"
ORIGIN      
        1 mirrtlllqq liisvvllrl haqhednssg qngsrkdtgi stlessltls rnsaiwptlm
       61 qstvndapii aaaeaknilr tysiakqptp lsklssqnhs tefsaqpnsk pepeqeivss
      121 ssfhptisks gfhhqpiltt takfakpfad gsshlamhsa qvpqltvhge dpqplpepna
      181 vkvsgaslmp syqnnafedd teqfddedds sadssrpgai dneaieelvn rflngddted
      241 gkeeklnkea lklinsskyw dlnnlqpens irdskkaqew mngyaveaqk vlrevalagw
      301 nyvtsvshlt kqlldeaeet lgkfvkstsk qakqfdtkai edeslkrqfe lllveginvl
      361 dendfneyne lqkliakaya etsvcetsna ticpyrvsdi vsiiahendg pkafrfwial
      421 realgpklvt sykrlielin kgaklngfpd ggamwrspye rfasrrekte qsdtvallqk
      481 lyqqinpfyk qlhayirrqi palyglanvs nltrdgpipa hllksiasdn wvafyrdtkp
      541 yqdedhlare vqenfqklny tvknmfkqty ktlkqlgfdk lpssfwtksi ftrtwskdml
      601 chppaaydmr dkhdyrikac ahlnlpdfel thkllvhiyh yymcrdqpll freatnpsll
      661 tavtnafain arnieylkmm klitsetgfs hskiinrlyl ealedfvklp fdfavdmwrf
      721 hifdgtstna twnsdwwqls elfqgikspv erkstdfdai afstiaqtha pamkhffayi
      781 mqfqilkalc pdttnlsngc mlernsvidk ikkvmalgss itwrealeii tgskevdasa
      841 mleyyqplis wleeqnakeh ayigwdgfgk pfeesevpkv resttstdsl seilsgsqfa
      901 fpggdcsngk eclldsvcqn dlceckegly tlkigntync vpgnpadagf gdghgglvig
      961 lhsiddnsiv aipepeehek qmkaepepel andkpgflpe qelkskgtsa siptltlvls
     1021 ltvlvvll
//