GenomeNet

Database: RefSeq
Entry: XP_005265410
LinkDB: XP_005265410
Original site: XP_005265410 
LOCUS       XP_005265410            1416 aa            linear   PRI 26-MAR-2018
DEFINITION  receptor-type tyrosine-protein phosphatase gamma isoform X4 [Homo
            sapiens].
ACCESSION   XP_005265410
VERSION     XP_005265410.1
DBLINK      BioProject: PRJNA168
DBSOURCE    REFSEQ: accession XM_005265353.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Homo sapiens Annotation Release 109
            Annotation Version          :: 109
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     Protein         1..1416
                     /product="receptor-type tyrosine-protein phosphatase gamma
                     isoform X4"
                     /calculated_mol_wt=158640
     variation       1
                     /replace="i"
                     /db_xref="dbSNP:907192750"
     variation       2
                     /replace="q"
                     /db_xref="dbSNP:1313122480"
     variation       2
                     /replace="r"
                     /db_xref="dbSNP:781512274"
     variation       2
                     /replace="w"
                     /db_xref="dbSNP:757376169"
     variation       3
                     /replace="s"
                     /db_xref="dbSNP:754819414"
     variation       3
                     /replace="w"
                     /db_xref="dbSNP:753513295"
     variation       5
                     /replace="l"
                     /db_xref="dbSNP:1272065009"
     variation       5
                     /replace="l"
                     /db_xref="dbSNP:748070493"
     variation       5
                     /replace="p"
                     /db_xref="dbSNP:778628550"
     variation       6
                     /replace="e"
                     /db_xref="dbSNP:777239607"
     variation       6
                     /replace="q"
                     /db_xref="dbSNP:1230773127"
     variation       7
                     /replace="l"
                     /db_xref="dbSNP:770448137"
     variation       7
                     /replace="p"
                     /db_xref="dbSNP:1422650252"
     variation       7
                     /replace="s"
                     /db_xref="dbSNP:746543678"
     variation       8
                     /replace="y"
                     /db_xref="dbSNP:1015595407"
     variation       9
                     /replace="s"
                     /db_xref="dbSNP:776348805"
     variation       10
                     /replace="-"
                     /db_xref="dbSNP:779010394"
     variation       10
                     /replace="c"
                     /db_xref="dbSNP:1467205022"
     variation       11
                     /replace="f"
                     /db_xref="dbSNP:745565612"
     variation       11
                     /replace="t"
                     /db_xref="dbSNP:963262600"
     variation       12
                     /replace="l"
                     /db_xref="dbSNP:770192844"
     variation       13
                     /replace="l"
                     /db_xref="dbSNP:1449005789"
     variation       14
                     /replace="l"
                     /db_xref="dbSNP:763532615"
     variation       14
                     /replace="l"
                     /db_xref="dbSNP:77802872"
     variation       14
                     /replace="p"
                     /db_xref="dbSNP:1381071275"
     variation       15
                     /replace="n"
                     /db_xref="dbSNP:764724150"
     variation       16
                     /replace="i"
                     /db_xref="dbSNP:375586923"
     variation       16
                     /replace="n"
                     /db_xref="dbSNP:761960149"
     variation       16
                     /replace="v"
                     /db_xref="dbSNP:774536606"
     Region          17..272
                     /region_name="PLN02179"
                     /note="carbonic anhydrase"
                     /db_xref="CDD:177835"
     variation       17
                     /replace="a"
                     /db_xref="dbSNP:140017853"
     variation       17
                     /replace="i"
                     /db_xref="dbSNP:1231014002"
     variation       17
                     /replace="t"
                     /db_xref="dbSNP:556669186"
     variation       18
                     /replace="g"
                     /db_xref="dbSNP:868456918"
     variation       18
                     /replace="i"
                     /db_xref="dbSNP:764982198"
     variation       19
                     /replace="f"
                     /db_xref="dbSNP:1484860890"
     variation       19
                     /replace="s"
                     /db_xref="dbSNP:149847925"
     variation       20
                     /replace="l"
                     /db_xref="dbSNP:758281367"
     variation       20
                     /replace="v"
                     /db_xref="dbSNP:1479071038"
     variation       21
                     /replace="f"
                     /db_xref="dbSNP:146419543"
     variation       21
                     /replace="p"
                     /db_xref="dbSNP:746435697"
     variation       22
                     /replace="l"
                     /db_xref="dbSNP:756803785"
     variation       22
                     /replace="q"
                     /db_xref="dbSNP:780635320"
     variation       22
                     /replace="y"
                     /db_xref="dbSNP:924986196"
     variation       23
                     /replace="y"
                     /db_xref="dbSNP:1170625687"
     variation       24
                     /replace="a"
                     /db_xref="dbSNP:745504638"
     variation       24
                     /replace="v"
                     /db_xref="dbSNP:936574527"
     variation       25
                     /replace="m"
                     /db_xref="dbSNP:1192366180"
     variation       26
                     /replace="c"
                     /db_xref="dbSNP:142428806"
     variation       27
                     /replace="f"
                     /db_xref="dbSNP:1312235605"
     variation       28
                     /replace="a"
                     /db_xref="dbSNP:1437512391"
     variation       28
                     /replace="p"
                     /db_xref="dbSNP:775949428"
     variation       29
                     /replace="a"
                     /db_xref="dbSNP:201950893"
     variation       29
                     /replace="e"
                     /db_xref="dbSNP:200002839"
     variation       29
                     /replace="t"
                     /db_xref="dbSNP:2365955"
     variation       31
                     /replace="i"
                     /db_xref="dbSNP:367661472"
     variation       34
                     /replace="h"
                     /db_xref="dbSNP:759811510"
     variation       34
                     /replace="y"
                     /db_xref="dbSNP:763846414"
     variation       35
                     /replace="a"
                     /db_xref="dbSNP:761762238"
     variation       35
                     /replace="i"
                     /db_xref="dbSNP:751360182"
     variation       36
                     /replace="v"
                     /db_xref="dbSNP:749884853"
     variation       37
                     /replace="a"
                     /db_xref="dbSNP:1203691421"
     variation       37
                     /replace="t"
                     /db_xref="dbSNP:1274346788"
     variation       37
                     /replace="v"
                     /db_xref="dbSNP:755701148"
     variation       38
                     /replace="l"
                     /db_xref="dbSNP:1344895197"
     variation       39
                     /replace="h"
                     /db_xref="dbSNP:753540838"
     variation       39
                     /replace="r"
                     /db_xref="dbSNP:779771989"
     variation       40
                     /replace="k"
                     /db_xref="dbSNP:754714757"
     variation       41
                     /replace="n"
                     /db_xref="dbSNP:371539304"
     variation       42
                     /replace="g"
                     /db_xref="dbSNP:1279293276"
     variation       42
                     /replace="s"
                     /db_xref="dbSNP:772588126"
     variation       43
                     /replace="h"
                     /db_xref="dbSNP:112845451"
     variation       43
                     /replace="y"
                     /db_xref="dbSNP:1014864174"
     variation       44
                     /replace="d"
                     /db_xref="dbSNP:200922257"
     variation       44
                     /replace="s"
                     /db_xref="dbSNP:747031451"
     variation       45
                     /replace="n"
                     /db_xref="dbSNP:776732483"
     variation       45
                     /replace="s"
                     /db_xref="dbSNP:546223591"
     variation       46
                     /replace="a"
                     /db_xref="dbSNP:147819655"
     variation       46
                     /replace="e"
                     /db_xref="dbSNP:1362950993"
     variation       46
                     /replace="s"
                     /db_xref="dbSNP:1179424376"
     variation       48
                     /replace="h"
                     /db_xref="dbSNP:761521271"
     variation       50
                     /replace="c"
                     /db_xref="dbSNP:1045085660"
     variation       50
                     /replace="h"
                     /db_xref="dbSNP:1460443941"
     variation       50
                     /replace="r"
                     /db_xref="dbSNP:898187112"
     variation       51
                     /replace="g"
                     /db_xref="dbSNP:767434065"
     variation       52
                     /replace="c"
                     /db_xref="dbSNP:750318678"
     variation       52
                     /replace="h"
                     /db_xref="dbSNP:760765025"
     variation       53
                     /replace="e"
                     /db_xref="dbSNP:1328614298"
     variation       54
                     /replace="s"
                     /db_xref="dbSNP:1341446197"
     variation       55
                     /replace="s"
                     /db_xref="dbSNP:1417231357"
     variation       56
                     /replace="d"
                     /db_xref="dbSNP:1366792081"
     variation       56
                     /replace="g"
                     /db_xref="dbSNP:150368253"
     variation       57
                     /replace="n"
                     /db_xref="dbSNP:753443145"
     variation       58
                     /replace="l"
                     /db_xref="dbSNP:376043244"
     variation       58
                     /replace="p"
                     /db_xref="dbSNP:77715924"
     variation       58
                     /replace="t"
                     /db_xref="dbSNP:549855202"
     variation       59
                     /replace="h"
                     /db_xref="dbSNP:1337711053"
     variation       60
                     /replace="r"
                     /db_xref="dbSNP:1468683681"
     variation       61
                     /replace="a"
                     /db_xref="dbSNP:1249637984"
     variation       61
                     /replace="v"
                     /db_xref="dbSNP:529043825"
     variation       62
                     /replace="y"
                     /db_xref="dbSNP:1442773933"
     variation       63
                     /replace="p"
                     /db_xref="dbSNP:1190039714"
     variation       65
                     /replace="a"
                     /db_xref="dbSNP:1441255692"
     variation       65
                     /replace="g"
                     /db_xref="dbSNP:777179928"
     variation       66
                     /replace="c"
                     /db_xref="dbSNP:760184818"
     Region          67..319
                     /region_name="alpha_CARP_receptor_like"
                     /note="Carbonic anhydrase alpha related protein,
                     receptor_like subfamily. Carbonic anhydrase related
                     proteins (CARPs) are sequence similar to carbonic
                     anhydrases. Carbonic anhydrases are zinc-containing
                     enzymes that catalyze the reversible hydration of
                     carbon...; cd03122"
                     /db_xref="CDD:239396"
     variation       67
                     /replace="a"
                     /db_xref="dbSNP:1369295758"
     variation       68
                     /replace="s"
                     /db_xref="dbSNP:1275172893"
     variation       69
                     /replace="e"
                     /db_xref="dbSNP:1280453485"
     variation       69
                     /replace="q"
                     /db_xref="dbSNP:548690736"
     variation       70
                     /replace="d"
                     /db_xref="dbSNP:752873025"
     variation       70
                     /replace="h"
                     /db_xref="dbSNP:138626992"
     variation       72
                     /replace="i"
                     /db_xref="dbSNP:762482513"
     variation       73
                     /replace="m"
                     /db_xref="dbSNP:182010071"
     variation       73
                     /replace="s"
                     /db_xref="dbSNP:764381582"
     variation       73
                     /replace="t"
                     /db_xref="dbSNP:187568366"
     variation       74
                     /replace="s"
                     /db_xref="dbSNP:1215837232"
     variation       75
                     /replace="g"
                     /db_xref="dbSNP:779782866"
     variation       75
                     /replace="i"
                     /db_xref="dbSNP:1034440786"
     variation       75
                     /replace="s"
                     /db_xref="dbSNP:1197924162"
     variation       76
                     /replace="i"
                     /db_xref="dbSNP:749221166"
     variation       77
                     /replace="i"
                     /db_xref="dbSNP:754961930"
     variation       77
                     /replace="s"
                     /db_xref="dbSNP:1228815831"
     variation       79
                     /replace="g"
                     /db_xref="dbSNP:778350039"
     variation       79
                     /replace="w"
                     /db_xref="dbSNP:960375424"
     variation       80
                     /replace="d"
                     /db_xref="dbSNP:771641444"
     variation       80
                     /replace="s"
                     /db_xref="dbSNP:533936687"
     variation       81
                     /replace="c"
                     /db_xref="dbSNP:1391863290"
     variation       81
                     /replace="h"
                     /db_xref="dbSNP:148761591"
     variation       82
                     /replace="q"
                     /db_xref="dbSNP:746695290"
     variation       85
                     /replace="l"
                     /db_xref="dbSNP:1337894893"
     variation       86
                     /replace="t"
                     /db_xref="dbSNP:776898840"
     variation       86
                     /replace="v"
                     /db_xref="dbSNP:369148891"
     variation       87
                     /replace="n"
                     /db_xref="dbSNP:760096756"
     variation       88
                     /replace="i"
                     /db_xref="dbSNP:765867701"
     variation       89
                     /replace="f"
                     /db_xref="dbSNP:201787131"
     variation       90
                     /replace="e"
                     /db_xref="dbSNP:1271291122"
     variation       92
                     /replace="h"
                     /db_xref="dbSNP:62620047"
     variation       93
                     /replace="a"
                     /db_xref="dbSNP:765996492"
     variation       94
                     /replace="c"
                     /db_xref="dbSNP:764140516"
     variation       94
                     /replace="h"
                     /db_xref="dbSNP:751803837"
     variation       95
                     /replace="a"
                     /db_xref="dbSNP:916309143"
     variation       95
                     /replace="f"
                     /db_xref="dbSNP:141896316"
     variation       96
                     /replace="a"
                     /db_xref="dbSNP:1475465846"
     variation       99
                     /replace="n"
                     /db_xref="dbSNP:866137873"
     variation       100
                     /replace="p"
                     /db_xref="dbSNP:1189460089"
     variation       100
                     /replace="q"
                     /db_xref="dbSNP:754875077"
     variation       100
                     /replace="r"
                     /db_xref="dbSNP:753659640"
     variation       101
                     /replace="d"
                     /db_xref="dbSNP:1399137792"
     variation       101
                     /replace="k"
                     /db_xref="dbSNP:1488842070"
     variation       101
                     /replace="v"
                     /db_xref="dbSNP:1168118799"
     variation       103
                     /replace="q"
                     /db_xref="dbSNP:1316053208"
     variation       104
                     /replace="l"
                     /db_xref="dbSNP:778822401"
     variation       105
                     /replace="n"
                     /db_xref="dbSNP:747596109"
     variation       107
                     /replace="f"
                     /db_xref="dbSNP:757888445"
     variation       107
                     /replace="l"
                     /db_xref="dbSNP:1370704506"
     variation       108
                     /replace="g"
                     /db_xref="dbSNP:867286501"
     variation       108
                     /replace="n"
                     /db_xref="dbSNP:1417094798"
     variation       109
                     /replace="d"
                     /db_xref="dbSNP:201085188"
     variation       109
                     /replace="s"
                     /db_xref="dbSNP:746640868"
     variation       110
                     /replace="g"
                     /db_xref="dbSNP:1253261995"
     variation       111
                     /replace="c"
                     /db_xref="dbSNP:1193880383"
     variation       111
                     /replace="p"
                     /db_xref="dbSNP:770537874"
     variation       113
                     /replace="k"
                     /db_xref="dbSNP:1231794514"
     variation       115
                     /replace="t"
                     /db_xref="dbSNP:781571322"
     variation       116
                     /replace="*"
                     /db_xref="dbSNP:1485961197"
     variation       117
                     /replace="r"
                     /db_xref="dbSNP:746266399"
     variation       118
                     /replace="r"
                     /db_xref="dbSNP:1254847076"
     variation       119
                     /replace="n"
                     /db_xref="dbSNP:370416021"
     variation       120
                     /replace="r"
                     /db_xref="dbSNP:897108624"
     variation       121
                     /replace="r"
                     /db_xref="dbSNP:1189542511"
     variation       122
                     /replace="*"
                     /db_xref="dbSNP:1392567337"
     variation       122
                     /replace="k"
                     /db_xref="dbSNP:1193502740"
     variation       123
                     /replace="k"
                     /db_xref="dbSNP:1422649186"
     variation       124
                     /replace="v"
                     /db_xref="dbSNP:761799368"
     variation       125
                     /replace="d"
                     /db_xref="dbSNP:773413749"
     variation       125
                     /replace="t"
                     /db_xref="dbSNP:772283947"
     variation       126
                     /replace="v"
                     /db_xref="dbSNP:140777402"
     variation       128
                     /replace="m"
                     /db_xref="dbSNP:1262040776"
     variation       130
                     /replace="d"
                     /db_xref="dbSNP:189356599"
     variation       131
                     /replace="a"
                     /db_xref="dbSNP:370339396"
     variation       131
                     /replace="n"
                     /db_xref="dbSNP:752539487"
     variation       132
                     /replace="c"
                     /db_xref="dbSNP:373590197"
     variation       135
                     /replace="r"
                     /db_xref="dbSNP:1192162450"
     variation       138
                     /replace="v"
                     /db_xref="dbSNP:780914955"
     variation       139
                     /replace="l"
                     /db_xref="dbSNP:1474978049"
     variation       139
                     /replace="p"
                     /db_xref="dbSNP:750068236"
     variation       140
                     /replace="l"
                     /db_xref="dbSNP:755877507"
     variation       141
                     /replace="g"
                     /db_xref="dbSNP:1456744412"
     variation       141
                     /replace="s"
                     /db_xref="dbSNP:1161897370"
     variation       141
                     /replace="v"
                     /db_xref="dbSNP:1362184918"
     variation       141
                     /replace="w"
                     /db_xref="dbSNP:766805370"
     variation       143
                     /replace="l"
                     /db_xref="dbSNP:1396985553"
     variation       143
                     /replace="y"
                     /db_xref="dbSNP:1165690037"
     variation       144
                     /replace="e"
                     /db_xref="dbSNP:780514305"
     variation       145
                     /replace="a"
                     /db_xref="dbSNP:1195295995"
     variation       145
                     /replace="s"
                     /db_xref="dbSNP:749642322"
     variation       146
                     /replace="e"
                     /db_xref="dbSNP:908850824"
     variation       146
                     /replace="k"
                     /db_xref="dbSNP:1366630957"
     variation       148
                     /replace="m"
                     /db_xref="dbSNP:755442122"
     variation       148
                     /replace="v"
                     /db_xref="dbSNP:140851159"
     variation       149
                     /replace="a"
                     /db_xref="dbSNP:748752255"
     variation       149
                     /replace="e"
                     /db_xref="dbSNP:1227269518"
     variation       152
                     /replace="*"
                     /db_xref="dbSNP:1273206285"
     variation       152
                     /replace="c"
                     /db_xref="dbSNP:1336499876"
     variation       153
                     /replace="g"
                     /db_xref="dbSNP:867441157"
     variation       153
                     /replace="s"
                     /db_xref="dbSNP:772137991"
     variation       154
                     /replace="y"
                     /db_xref="dbSNP:553923548"
     variation       155
                     /replace="t"
                     /db_xref="dbSNP:747211567"
     variation       156
                     /replace="s"
                     /db_xref="dbSNP:201734186"
     variation       157
                     /replace="v"
                     /db_xref="dbSNP:757115800"
     variation       158
                     /replace="p"
                     /db_xref="dbSNP:771166810"
     variation       158
                     /replace="s"
                     /db_xref="dbSNP:775226099"
     variation       159
                     /replace="a"
                     /db_xref="dbSNP:371488686"
     variation       159
                     /replace="p"
                     /db_xref="dbSNP:758480466"
     variation       159
                     /replace="v"
                     /db_xref="dbSNP:367774512"
     variation       160
                     /replace="a"
                     /db_xref="dbSNP:1164323504"
     variation       160
                     /replace="g"
                     /db_xref="dbSNP:1038831841"
     variation       164
                     /replace="n"
                     /db_xref="dbSNP:774150743"
     variation       164
                     /replace="s"
                     /db_xref="dbSNP:761849753"
     variation       165
                     /replace="v"
                     /db_xref="dbSNP:374973218"
     variation       166
                     /replace="h"
                     /db_xref="dbSNP:1348571652"
     variation       166
                     /replace="s"
                     /db_xref="dbSNP:372067576"
     variation       169
                     /replace="g"
                     /db_xref="dbSNP:755784901"
     variation       170
                     /replace="s"
                     /db_xref="dbSNP:1169421615"
     variation       170
                     /replace="v"
                     /db_xref="dbSNP:766130550"
     variation       172
                     /replace="a"
                     /db_xref="dbSNP:754169873"
     variation       172
                     /replace="i"
                     /db_xref="dbSNP:1226305258"
     variation       174
                     /replace="i"
                     /db_xref="dbSNP:1173896251"
     variation       174
                     /replace="t"
                     /db_xref="dbSNP:1186894265"
     variation       176
                     /replace="m"
                     /db_xref="dbSNP:1388140984"
     variation       178
                     /replace="l"
                     /db_xref="dbSNP:781371391"
     variation       181
                     /replace="p"
                     /db_xref="dbSNP:144683833"
     variation       181
                     /replace="s"
                     /db_xref="dbSNP:746053568"
     variation       182
                     /replace="g"
                     /db_xref="dbSNP:778530372"
     variation       183
                     /replace="e"
                     /db_xref="dbSNP:747958857"
     variation       185
                     /replace="d"
                     /db_xref="dbSNP:1345263463"
     variation       188
                     /replace="e"
                     /db_xref="dbSNP:772073947"
     variation       188
                     /replace="h"
                     /db_xref="dbSNP:773265177"
     variation       189
                     /replace="i"
                     /db_xref="dbSNP:770352433"
     variation       189
                     /replace="t"
                     /db_xref="dbSNP:535933860"
     variation       190
                     /replace="s"
                     /db_xref="dbSNP:866875275"
     variation       191
                     /replace="v"
                     /db_xref="dbSNP:373688958"
     variation       192
                     /replace="f"
                     /db_xref="dbSNP:148863663"
     variation       194
                     /replace="n"
                     /db_xref="dbSNP:1219156015"
     variation       195
                     /replace="k"
                     /db_xref="dbSNP:764974968"
     variation       196
                     /replace="i"
                     /db_xref="dbSNP:377604908"
     variation       196
                     /replace="l"
                     /db_xref="dbSNP:752939187"
     variation       197
                     /replace="i"
                     /db_xref="dbSNP:374241237"
     variation       198
                     /replace="g"
                     /db_xref="dbSNP:1469036653"
     variation       198
                     /replace="r"
                     /db_xref="dbSNP:1226700841"
     variation       199
                     /replace="g"
                     /db_xref="dbSNP:1012434793"
     variation       199
                     /replace="t"
                     /db_xref="dbSNP:750545987"
     variation       200
                     /replace="l"
                     /db_xref="dbSNP:756221008"
     variation       201
                     /replace="a"
                     /db_xref="dbSNP:780333241"
     variation       202
                     /replace="v"
                     /db_xref="dbSNP:749574861"
     variation       203
                     /replace="l"
                     /db_xref="dbSNP:1381823174"
     variation       206
                     /replace="i"
                     /db_xref="dbSNP:1408465065"
     variation       206
                     /replace="v"
                     /db_xref="dbSNP:1019199980"
     variation       207
                     /replace="-"
                     /db_xref="dbSNP:1287882119"
     variation       207
                     /replace="t"
                     /db_xref="dbSNP:754085336"
     variation       208
                     /replace="l"
                     /db_xref="dbSNP:61757808"
     variation       208
                     /replace="p"
                     /db_xref="dbSNP:533835628"
     variation       209
                     /replace="t"
                     /db_xref="dbSNP:779981819"
     variation       211
                     /replace="n"
                     /db_xref="dbSNP:746834721"
     variation       211
                     /replace="s"
                     /db_xref="dbSNP:777665676"
     variation       211
                     /replace="y"
                     /db_xref="dbSNP:1432319436"
     variation       212
                     /replace="c"
                     /db_xref="dbSNP:757076816"
     variation       213
                     /replace="a"
                     /db_xref="dbSNP:895609830"
     variation       215
                     /replace="e"
                     /db_xref="dbSNP:1250496640"
     variation       215
                     /replace="g"
                     /db_xref="dbSNP:140916981"
     variation       215
                     /replace="h"
                     /db_xref="dbSNP:200790873"
     variation       217
                     /replace="i"
                     /db_xref="dbSNP:371016927"
     variation       217
                     /replace="v"
                     /db_xref="dbSNP:769343658"
     variation       218
                     /replace="i"
                     /db_xref="dbSNP:145318908"
     variation       219
                     /replace="h"
                     /db_xref="dbSNP:149393059"
     variation       219
                     /replace="r"
                     /db_xref="dbSNP:768326759"
     variation       219
                     /replace="y"
                     /db_xref="dbSNP:968467831"
     variation       220
                     /replace="a"
                     /db_xref="dbSNP:188991589"
     variation       220
                     /replace="g"
                     /db_xref="dbSNP:180851782"
     variation       220
                     /replace="r"
                     /db_xref="dbSNP:762248211"
     variation       222
                     /replace="k"
                     /db_xref="dbSNP:144784343"
     variation       224
                     /replace="i"
                     /db_xref="dbSNP:766549529"
     variation       224
                     /replace="v"
                     /db_xref="dbSNP:753995594"
     variation       227
                     /replace="p"
                     /db_xref="dbSNP:1290478392"
     variation       228
                     /replace="d"
                     /db_xref="dbSNP:1205395178"
     variation       230
                     /replace="v"
                     /db_xref="dbSNP:1249533096"
     variation       231
                     /replace="n"
                     /db_xref="dbSNP:1463225452"
     variation       232
                     /replace="s"
                     /db_xref="dbSNP:1244622049"
     variation       233
                     /replace="l"
                     /db_xref="dbSNP:371886900"
     variation       233
                     /replace="p"
                     /db_xref="dbSNP:540239293"
     variation       234
                     /replace="e"
                     /db_xref="dbSNP:776788449"
     variation       234
                     /replace="h"
                     /db_xref="dbSNP:1254016406"
     variation       235
                     /replace="a"
                     /db_xref="dbSNP:759703682"
     variation       236
                     /replace="f"
                     /db_xref="dbSNP:776285819"
     variation       237
                     /replace="i"
                     /db_xref="dbSNP:200434651"
     variation       238
                     /replace="f"
                     /db_xref="dbSNP:1027544316"
     variation       239
                     /replace="g"
                     /db_xref="dbSNP:767293119"
     variation       239
                     /replace="q"
                     /db_xref="dbSNP:755977831"
     variation       239
                     /replace="r"
                     /db_xref="dbSNP:779979544"
     variation       241
                     /replace="f"
                     /db_xref="dbSNP:753827434"
     variation       242
                     /replace="l"
                     /db_xref="dbSNP:1368024774"
     variation       243
                     /replace="p"
                     /db_xref="dbSNP:1388496513"
     variation       245
                     /replace="f"
                     /db_xref="dbSNP:577302571"
     variation       245
                     /replace="t"
                     /db_xref="dbSNP:368477619"
     variation       246
                     /replace="l"
                     /db_xref="dbSNP:747817897"
     variation       246
                     /replace="m"
                     /db_xref="dbSNP:1447283842"
     variation       247
                     /replace="s"
                     /db_xref="dbSNP:200806155"
     variation       250
                     /replace="c"
                     /db_xref="dbSNP:1326720096"
     variation       251
                     /replace="q"
                     /db_xref="dbSNP:921686524"
     variation       251
                     /replace="r"
                     /db_xref="dbSNP:946861469"
     variation       255
                     /replace="s"
                     /db_xref="dbSNP:1266456887"
     variation       256
                     /replace="l"
                     /db_xref="dbSNP:376821615"
     variation       257
                     /replace="i"
                     /db_xref="dbSNP:747341353"
     variation       257
                     /replace="p"
                     /db_xref="dbSNP:1208394697"
     variation       257
                     /replace="t"
                     /db_xref="dbSNP:771507978"
     variation       258
                     /replace="a"
                     /db_xref="dbSNP:777267158"
     variation       258
                     /replace="i"
                     /db_xref="dbSNP:1409838361"
     variation       258
                     /replace="t"
                     /db_xref="dbSNP:760188470"
     variation       260
                     /replace="p"
                     /db_xref="dbSNP:544685091"
     variation       260
                     /replace="s"
                     /db_xref="dbSNP:1436111108"
     variation       262
                     /replace="s"
                     /db_xref="dbSNP:1350292124"
     variation       263
                     /replace="k"
                     /db_xref="dbSNP:563123759"
     variation       266
                     /replace="e"
                     /db_xref="dbSNP:1459276811"
     variation       268
                     /replace="l"
                     /db_xref="dbSNP:147249332"
     variation       268
                     /replace="m"
                     /db_xref="dbSNP:1056462608"
     variation       269
                     /replace="a"
                     /db_xref="dbSNP:775454102"
     variation       269
                     /replace="i"
                     /db_xref="dbSNP:1330863902"
     variation       271
                     /replace="q"
                     /db_xref="dbSNP:764224575"
     variation       271
                     /replace="w"
                     /db_xref="dbSNP:368783424"
     variation       273
                     /replace="a"
                     /db_xref="dbSNP:750173117"
     variation       273
                     /replace="p"
                     /db_xref="dbSNP:371752893"
     variation       274
                     /replace="i"
                     /db_xref="dbSNP:181919998"
     variation       275
                     /replace="p"
                     /db_xref="dbSNP:201974785"
     variation       277
                     /replace="c"
                     /db_xref="dbSNP:1006607746"
     variation       278
                     /replace="*"
                     /db_xref="dbSNP:1323100472"
     variation       279
                     /replace="l"
                     /db_xref="dbSNP:1219838950"
     variation       281
                     /replace="f"
                     /db_xref="dbSNP:749870410"
     variation       283
                     /replace="s"
                     /db_xref="dbSNP:1342159175"
     variation       285
                     /replace="y"
                     /db_xref="dbSNP:768583792"
     variation       287
                     /replace="v"
                     /db_xref="dbSNP:774537313"
     variation       288
                     /replace="f"
                     /db_xref="dbSNP:866132859"
     variation       290
                     /replace="t"
                     /db_xref="dbSNP:748317629"
     variation       292
                     /replace="l"
                     /db_xref="dbSNP:1420710637"
     variation       294
                     /replace="d"
                     /db_xref="dbSNP:772315604"
     variation       295
                     /replace="h"
                     /db_xref="dbSNP:1269036541"
     variation       296
                     /replace="v"
                     /db_xref="dbSNP:1466378724"
     variation       298
                     /replace="s"
                     /db_xref="dbSNP:376642650"
     variation       300
                     /replace="e"
                     /db_xref="dbSNP:759343615"
     variation       301
                     /replace="y"
                     /db_xref="dbSNP:911872298"
     variation       303
                     /replace="g"
                     /db_xref="dbSNP:879190600"
     variation       304
                     /replace="i"
                     /db_xref="dbSNP:1195960021"
     variation       304
                     /replace="n"
                     /db_xref="dbSNP:765140931"
     variation       306
                     /replace="l"
                     /db_xref="dbSNP:1426710891"
     variation       307
                     /replace="r"
                     /db_xref="dbSNP:775286532"
     variation       308
                     /replace="p"
                     /db_xref="dbSNP:968489028"
     variation       308
                     /replace="s"
                     /db_xref="dbSNP:762988412"
     variation       310
                     /replace="k"
                     /db_xref="dbSNP:763492567"
     variation       310
                     /replace="q"
                     /db_xref="dbSNP:1319033562"
     variation       311
                     /replace="c"
                     /db_xref="dbSNP:762084994"
     variation       311
                     /replace="h"
                     /db_xref="dbSNP:1437859583"
     variation       311
                     /replace="r"
                     /db_xref="dbSNP:1277154900"
     variation       313
                     /replace="r"
                     /db_xref="dbSNP:566567864"
     variation       313
                     /replace="y"
                     /db_xref="dbSNP:1335361683"
     variation       314
                     /replace="n"
                     /db_xref="dbSNP:1285954023"
     variation       318
                     /replace="f"
                     /db_xref="dbSNP:750158140"
     variation       318
                     /replace="t"
                     /db_xref="dbSNP:1218737553"
     variation       319
                     /replace="k"
                     /db_xref="dbSNP:756429269"
     variation       320
                     /replace="s"
                     /db_xref="dbSNP:144721591"
     variation       321
                     /replace="a"
                     /db_xref="dbSNP:750527745"
     variation       321
                     /replace="t"
                     /db_xref="dbSNP:150839810"
     variation       322
                     /replace="i"
                     /db_xref="dbSNP:755528856"
     variation       323
                     /replace="c"
                     /db_xref="dbSNP:142366357"
     variation       323
                     /replace="h"
                     /db_xref="dbSNP:537743302"
     variation       325
                     /replace="a"
                     /db_xref="dbSNP:773413822"
     variation       326
                     /replace="c"
                     /db_xref="dbSNP:1397314871"
     variation       328
                     /replace="h"
                     /db_xref="dbSNP:747299296"
     variation       328
                     /replace="n"
                     /db_xref="dbSNP:1198071830"
     variation       329
                     /replace="g"
                     /db_xref="dbSNP:1453690040"
     variation       329
                     /replace="n"
                     /db_xref="dbSNP:1473398406"
     variation       330
                     /replace="i"
                     /db_xref="dbSNP:143449511"
     variation       335
                     /replace="r"
                     /db_xref="dbSNP:1181940749"
     variation       337
                     /replace="p"
                     /db_xref="dbSNP:556935985"
     variation       339
                     /replace="e"
                     /db_xref="dbSNP:1250797509"
     variation       340
                     /replace="t"
                     /db_xref="dbSNP:768642495"
     variation       342
                     /replace="a"
                     /db_xref="dbSNP:1325879945"
     variation       343
                     /replace="p"
                     /db_xref="dbSNP:1207698718"
     variation       344
                     /replace="e"
                     /db_xref="dbSNP:773939523"
     Region          348..438
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     variation       348
                     /replace="s"
                     /db_xref="dbSNP:1189159791"
     variation       349
                     /replace="p"
                     /db_xref="dbSNP:1216901433"
     variation       351
                     /replace="i"
                     /db_xref="dbSNP:1444433906"
     variation       351
                     /replace="t"
                     /db_xref="dbSNP:765661275"
     variation       353
                     /replace="v"
                     /db_xref="dbSNP:753172956"
     variation       354
                     /replace="k"
                     /db_xref="dbSNP:375736857"
     variation       355
                     /replace="l"
                     /db_xref="dbSNP:1428309272"
     variation       357
                     /replace="a"
                     /db_xref="dbSNP:777783028"
     variation       361
                     /replace="a"
                     /db_xref="dbSNP:1332809719"
     variation       361
                     /replace="m"
                     /db_xref="dbSNP:751693280"
     variation       361
                     /replace="t"
                     /db_xref="dbSNP:757361968"
     variation       362
                     /replace="t"
                     /db_xref="dbSNP:952319612"
     variation       362
                     /replace="v"
                     /db_xref="dbSNP:781461101"
     variation       364
                     /replace="k"
                     /db_xref="dbSNP:1283328961"
     variation       366
                     /replace="p"
                     /db_xref="dbSNP:370371012"
     variation       370
                     /replace="l"
                     /db_xref="dbSNP:746143640"
     variation       370
                     /replace="p"
                     /db_xref="dbSNP:768539358"
     variation       373
                     /replace="f"
                     /db_xref="dbSNP:778897296"
     variation       374
                     /replace="y"
                     /db_xref="dbSNP:1225140225"
     variation       375
                     /replace="q"
                     /db_xref="dbSNP:1345064339"
     variation       375
                     /replace="r"
                     /db_xref="dbSNP:748044908"
     variation       376
                     /replace="p"
                     /db_xref="dbSNP:1201629274"
     variation       378
                     /replace="v"
                     /db_xref="dbSNP:772164088"
     variation       379
                     /replace="v"
                     /db_xref="dbSNP:1460555759"
     variation       380
                     /replace="n"
                     /db_xref="dbSNP:146672455"
     variation       381
                     /replace="y"
                     /db_xref="dbSNP:1250284578"
     variation       383
                     /replace="f"
                     /db_xref="dbSNP:746545159"
     variation       383
                     /replace="i"
                     /db_xref="dbSNP:770407382"
     variation       384
                     /replace="s"
                     /db_xref="dbSNP:1476626107"
     variation       385
                     /replace="y"
                     /db_xref="dbSNP:987460374"
     variation       386
                     /replace="i"
                     /db_xref="dbSNP:776346428"
     variation       386
                     /replace="s"
                     /db_xref="dbSNP:1268344812"
     variation       387
                     /replace="*"
                     /db_xref="dbSNP:1203628794"
     variation       388
                     /replace="s"
                     /db_xref="dbSNP:1170837148"
     variation       392
                     /replace="a"
                     /db_xref="dbSNP:759230918"
     variation       392
                     /replace="d"
                     /db_xref="dbSNP:113199298"
     variation       393
                     /replace="k"
                     /db_xref="dbSNP:763411756"
     variation       397
                     /replace="a"
                     /db_xref="dbSNP:1390532391"
     variation       397
                     /replace="m"
                     /db_xref="dbSNP:764590925"
     variation       397
                     /replace="t"
                     /db_xref="dbSNP:752062365"
     variation       398
                     /replace="l"
                     /db_xref="dbSNP:1214787191"
     variation       398
                     /replace="y"
                     /db_xref="dbSNP:138456939"
     variation       400
                     /replace="q"
                     /db_xref="dbSNP:750635968"
     variation       401
                     /replace="h"
                     /db_xref="dbSNP:1312605619"
     variation       402
                     /replace="n"
                     /db_xref="dbSNP:756424064"
     variation       402
                     /replace="s"
                     /db_xref="dbSNP:943364988"
     variation       403
                     /replace="d"
                     /db_xref="dbSNP:747958982"
     variation       403
                     /replace="g"
                     /db_xref="dbSNP:778807385"
     variation       403
                     /replace="n"
                     /db_xref="dbSNP:1208950374"
     variation       404
                     /replace="q"
                     /db_xref="dbSNP:1204870252"
     variation       405
                     /replace="e"
                     /db_xref="dbSNP:777757156"
     variation       405
                     /replace="h"
                     /db_xref="dbSNP:535321914"
     variation       409
                     /replace="i"
                     /db_xref="dbSNP:1409918741"
     variation       410
                     /replace="i"
                     /db_xref="dbSNP:777472818"
     variation       410
                     /replace="v"
                     /db_xref="dbSNP:758267170"
     variation       411
                     /replace="g"
                     /db_xref="dbSNP:746947603"
     variation       411
                     /replace="s"
                     /db_xref="dbSNP:1345876101"
     variation       412
                     /replace="h"
                     /db_xref="dbSNP:7650104"
     variation       412
                     /replace="r"
                     /db_xref="dbSNP:757164566"
     variation       413
                     /replace="v"
                     /db_xref="dbSNP:745387716"
     variation       414
                     /replace="*"
                     /db_xref="dbSNP:201240036"
     variation       415
                     /replace="p"
                     /db_xref="dbSNP:574073526"
     variation       415
                     /replace="r"
                     /db_xref="dbSNP:1343421705"
     variation       415
                     /replace="r"
                     /db_xref="dbSNP:1425382589"
     variation       416
                     /replace="g"
                     /db_xref="dbSNP:1257896535"
     variation       416
                     /replace="h"
                     /db_xref="dbSNP:748977953"
     variation       417
                     /replace="c"
                     /db_xref="dbSNP:1182641936"
     variation       417
                     /replace="r"
                     /db_xref="dbSNP:1425357262"
     variation       417
                     /replace="t"
                     /db_xref="dbSNP:1256642965"
     variation       421
                     /replace="l"
                     /db_xref="dbSNP:1181462732"
     variation       422
                     /replace="*"
                     /db_xref="dbSNP:769041418"
     variation       422
                     /replace="q"
                     /db_xref="dbSNP:372589382"
     variation       425
                     /replace="a"
                     /db_xref="dbSNP:61754215"
     variation       426
                     /replace="a"
                     /db_xref="dbSNP:1232394839"
     variation       426
                     /replace="l"
                     /db_xref="dbSNP:139041779"
     variation       428
                     /replace="q"
                     /db_xref="dbSNP:760822212"
     variation       428
                     /replace="w"
                     /db_xref="dbSNP:773365125"
     variation       429
                     /replace="n"
                     /db_xref="dbSNP:112710255"
     variation       429
                     /replace="s"
                     /db_xref="dbSNP:766635448"
     variation       430
                     /replace="n"
                     /db_xref="dbSNP:1450927100"
     variation       431
                     /replace="t"
                     /db_xref="dbSNP:759728947"
     Site            order(432..433,435..436)
                     /site_type="other"
                     /note="Cytokine receptor motif"
                     /db_xref="CDD:238020"
     variation       432
                     /replace="h"
                     /db_xref="dbSNP:890069022"
     variation       433
                     /replace="s"
                     /db_xref="dbSNP:763904315"
     variation       434
                     /replace="n"
                     /db_xref="dbSNP:751343662"
     variation       437
                     /replace="e"
                     /db_xref="dbSNP:1306960794"
     variation       437
                     /replace="h"
                     /db_xref="dbSNP:757153708"
     variation       438
                     /replace="m"
                     /db_xref="dbSNP:1033010129"
     variation       438
                     /replace="t"
                     /db_xref="dbSNP:781007376"
     variation       439
                     /replace="t"
                     /db_xref="dbSNP:1337089959"
     variation       440
                     /replace="l"
                     /db_xref="dbSNP:750425500"
     variation       442
                     /replace="h"
                     /db_xref="dbSNP:1401828882"
     variation       445
                     /replace="i"
                     /db_xref="dbSNP:1175225196"
     variation       445
                     /replace="t"
                     /db_xref="dbSNP:141885416"
     variation       446
                     /replace="t"
                     /db_xref="dbSNP:747899530"
     variation       447
                     /replace="r"
                     /db_xref="dbSNP:1316597203"
     variation       451
                     /replace="g"
                     /db_xref="dbSNP:890073836"
     variation       452
                     /replace="i"
                     /db_xref="dbSNP:758662228"
     variation       457
                     /replace="t"
                     /db_xref="dbSNP:944186579"
     variation       459
                     /replace="a"
                     /db_xref="dbSNP:1343688171"
     variation       459
                     /replace="m"
                     /db_xref="dbSNP:1042286400"
     variation       460
                     /replace="s"
                     /db_xref="dbSNP:1179183316"
     variation       461
                     /replace="i"
                     /db_xref="dbSNP:1347071910"
     variation       462
                     /replace="a"
                     /db_xref="dbSNP:757781094"
     variation       462
                     /replace="v"
                     /db_xref="dbSNP:747382591"
     variation       465
                     /replace="t"
                     /db_xref="dbSNP:1226567079"
     variation       465
                     /replace="v"
                     /db_xref="dbSNP:771434998"
     variation       466
                     /replace="c"
                     /db_xref="dbSNP:1383934168"
     variation       467
                     /replace="s"
                     /db_xref="dbSNP:781761603"
     variation       468
                     /replace="a"
                     /db_xref="dbSNP:769737875"
     variation       468
                     /replace="t"
                     /db_xref="dbSNP:746456916"
     variation       469
                     /replace="n"
                     /db_xref="dbSNP:371587393"
     variation       471
                     /replace="a"
                     /db_xref="dbSNP:1408474321"
     variation       472
                     /replace="p"
                     /db_xref="dbSNP:924797132"
     variation       473
                     /replace="v"
                     /db_xref="dbSNP:1328473195"
     variation       475
                     /replace="s"
                     /db_xref="dbSNP:775660224"
     variation       476
                     /replace="e"
                     /db_xref="dbSNP:1397991550"
     variation       476
                     /replace="g"
                     /db_xref="dbSNP:749430943"
     variation       477
                     /replace="f"
                     /db_xref="dbSNP:1316884430"
     variation       479
                     /replace="t"
                     /db_xref="dbSNP:1380566146"
     variation       481
                     /replace="a"
                     /db_xref="dbSNP:1277056618"
     variation       481
                     /replace="m"
                     /db_xref="dbSNP:376270678"
     variation       481
                     /replace="t"
                     /db_xref="dbSNP:544886184"
     variation       482
                     /replace="f"
                     /db_xref="dbSNP:1340897636"
     variation       483
                     /replace="c"
                     /db_xref="dbSNP:772929056"
     variation       485
                     /replace="n"
                     /db_xref="dbSNP:760447015"
     variation       486
                     /replace="l"
                     /db_xref="dbSNP:1442565821"
     variation       487
                     /replace="f"
                     /db_xref="dbSNP:1206045799"
     variation       489
                     /replace="l"
                     /db_xref="dbSNP:1444617292"
     variation       489
                     /replace="v"
                     /db_xref="dbSNP:1241673598"
     variation       490
                     /replace="l"
                     /db_xref="dbSNP:766226519"
     variation       491
                     /replace="a"
                     /db_xref="dbSNP:776399924"
     variation       492
                     /replace="v"
                     /db_xref="dbSNP:759569483"
     variation       493
                     /replace="t"
                     /db_xref="dbSNP:139904686"
     variation       494
                     /replace="i"
                     /db_xref="dbSNP:1057402875"
     variation       494
                     /replace="t"
                     /db_xref="dbSNP:1471070659"
     variation       497
                     /replace="v"
                     /db_xref="dbSNP:752287431"
     variation       499
                     /replace="s"
                     /db_xref="dbSNP:369588967"
     variation       502
                     /replace="g"
                     /db_xref="dbSNP:763853413"
     variation       505
                     /replace="a"
                     /db_xref="dbSNP:777192729"
     variation       509
                     /replace="l"
                     /db_xref="dbSNP:1296232401"
     variation       509
                     /replace="s"
                     /db_xref="dbSNP:373719298"
     variation       510
                     /replace="l"
                     /db_xref="dbSNP:757694918"
     variation       512
                     /replace="s"
                     /db_xref="dbSNP:781655266"
     variation       513
                     /replace="g"
                     /db_xref="dbSNP:750844339"
     variation       514
                     /replace="m"
                     /db_xref="dbSNP:756672469"
     variation       514
                     /replace="t"
                     /db_xref="dbSNP:376410542"
     variation       515
                     /replace="l"
                     /db_xref="dbSNP:369741263"
     variation       516
                     /replace="l"
                     /db_xref="dbSNP:1026457341"
     variation       517
                     /replace="a"
                     /db_xref="dbSNP:759038682"
     variation       517
                     /replace="t"
                     /db_xref="dbSNP:768781211"
     variation       518
                     /replace="s"
                     /db_xref="dbSNP:764776482"
     variation       518
                     /replace="v"
                     /db_xref="dbSNP:770692808"
     variation       519
                     /replace="l"
                     /db_xref="dbSNP:759353043"
     variation       519
                     /replace="l"
                     /db_xref="dbSNP:776508202"
     variation       520
                     /replace="g"
                     /db_xref="dbSNP:899152171"
     variation       521
                     /replace="f"
                     /db_xref="dbSNP:1428795599"
     variation       522
                     /replace="g"
                     /db_xref="dbSNP:139400616"
     variation       522
                     /replace="s"
                     /db_xref="dbSNP:1469110914"
     variation       523
                     /replace="g"
                     /db_xref="dbSNP:762543664"
     variation       523
                     /replace="s"
                     /db_xref="dbSNP:149885804"
     variation       525
                     /replace="d"
                     /db_xref="dbSNP:1380449542"
     variation       525
                     /replace="g"
                     /db_xref="dbSNP:777567761"
     variation       526
                     /replace="v"
                     /db_xref="dbSNP:1317086230"
     variation       527
                     /replace="s"
                     /db_xref="dbSNP:1345564935"
     variation       528
                     /replace="f"
                     /db_xref="dbSNP:763767189"
     variation       530
                     /replace="s"
                     /db_xref="dbSNP:1246737827"
     variation       531
                     /replace="a"
                     /db_xref="dbSNP:749009439"
     variation       531
                     /replace="g"
                     /db_xref="dbSNP:558967944"
     variation       532
                     /replace="a"
                     /db_xref="dbSNP:1211934929"
     variation       533
                     /replace="m"
                     /db_xref="dbSNP:1322324810"
     variation       535
                     /replace="a"
                     /db_xref="dbSNP:577368934"
     variation       536
                     /replace="m"
                     /db_xref="dbSNP:149063170"
     variation       536
                     /replace="t"
                     /db_xref="dbSNP:750801038"
     variation       537
                     /replace="c"
                     /db_xref="dbSNP:1205025610"
     variation       537
                     /replace="h"
                     /db_xref="dbSNP:372963270"
     variation       538
                     /replace="l"
                     /db_xref="dbSNP:1490866661"
     variation       539
                     /replace="a"
                     /db_xref="dbSNP:780597070"
     variation       539
                     /replace="l"
                     /db_xref="dbSNP:754408710"
     variation       539
                     /replace="p"
                     /db_xref="dbSNP:151090262"
     variation       540
                     /replace="a"
                     /db_xref="dbSNP:562881996"
     variation       540
                     /replace="m"
                     /db_xref="dbSNP:779012226"
     variation       540
                     /replace="t"
                     /db_xref="dbSNP:574774597"
     variation       541
                     /replace="a"
                     /db_xref="dbSNP:139395417"
     variation       542
                     /replace="t"
                     /db_xref="dbSNP:772371930"
     variation       543
                     /replace="a"
                     /db_xref="dbSNP:1366063291"
     variation       543
                     /replace="l"
                     /db_xref="dbSNP:559917459"
     variation       544
                     /replace="a"
                     /db_xref="dbSNP:143296465"
     variation       544
                     /replace="t"
                     /db_xref="dbSNP:1300672905"
     variation       544
                     /replace="v"
                     /db_xref="dbSNP:1344548288"
     variation       545
                     /replace="n"
                     /db_xref="dbSNP:1318363516"
     variation       545
                     /replace="s"
                     /db_xref="dbSNP:1309655450"
     variation       546
                     /replace="m"
                     /db_xref="dbSNP:1334385199"
     variation       548
                     /replace="a"
                     /db_xref="dbSNP:376371489"
     variation       548
                     /replace="e"
                     /db_xref="dbSNP:775496767"
     variation       548
                     /replace="t"
                     /db_xref="dbSNP:769538641"
     variation       549
                     /replace="t"
                     /db_xref="dbSNP:905525520"
     variation       550
                     /replace="r"
                     /db_xref="dbSNP:1021320278"
     variation       551
                     /replace="p"
                     /db_xref="dbSNP:1467963955"
     variation       551
                     /replace="s"
                     /db_xref="dbSNP:768229463"
     variation       552
                     /replace="d"
                     /db_xref="dbSNP:1481112447"
     variation       553
                     /replace="p"
                     /db_xref="dbSNP:1248643655"
     variation       553
                     /replace="v"
                     /db_xref="dbSNP:1179141540"
     variation       554
                     /replace="d"
                     /db_xref="dbSNP:192743559"
     variation       555
                     /replace="i"
                     /db_xref="dbSNP:138124307"
     variation       555
                     /replace="srvlat"
                     /db_xref="dbSNP:1364191143"
     variation       555
                     /replace="t"
                     /db_xref="dbSNP:763898172"
     variation       556
                     /replace="i"
                     /db_xref="dbSNP:761487116"
     variation       556
                     /replace="t"
                     /db_xref="dbSNP:1445505864"
     variation       557
                     /replace="g"
                     /db_xref="dbSNP:968772526"
     variation       558
                     /replace="g"
                     /db_xref="dbSNP:564162806"
     variation       559
                     /replace="f"
                     /db_xref="dbSNP:1364374805"
     variation       561
                     /replace="y"
                     /db_xref="dbSNP:201820508"
     variation       562
                     /replace="s"
                     /db_xref="dbSNP:1299548121"
     variation       563
                     /replace="r"
                     /db_xref="dbSNP:1393796295"
     variation       564
                     /replace="l"
                     /db_xref="dbSNP:761095761"
     variation       564
                     /replace="p"
                     /db_xref="dbSNP:766693477"
     Region          <565..622
                     /region_name="Prothymosin"
                     /note="Prothymosin/parathymosin family; pfam03247"
                     /db_xref="CDD:281265"
     variation       565
                     /replace="g"
                     /db_xref="dbSNP:549991785"
     variation       565
                     /replace="h"
                     /db_xref="dbSNP:754318982"
     variation       566
                     /replace="d"
                     /db_xref="dbSNP:938838750"
     variation       567
                     /replace="d"
                     /db_xref="dbSNP:1206659548"
     variation       567
                     /replace="y"
                     /db_xref="dbSNP:1308188232"
     variation       568
                     /replace="l"
                     /db_xref="dbSNP:201733832"
     variation       568
                     /replace="s"
                     /db_xref="dbSNP:746918640"
     variation       569
                     /replace="l"
                     /db_xref="dbSNP:1243516167"
     variation       569
                     /replace="p"
                     /db_xref="dbSNP:1197852003"
     variation       571
                     /replace="t"
                     /db_xref="dbSNP:1446411750"
     variation       572
                     /replace="k"
                     /db_xref="dbSNP:1181709051"
     variation       573
                     /replace="d"
                     /db_xref="dbSNP:866522804"
     variation       573
                     /replace="n"
                     /db_xref="dbSNP:1384479604"
     variation       574
                     /replace="d"
                     /db_xref="dbSNP:1006713640"
     variation       574
                     /replace="g"
                     /db_xref="dbSNP:747265374"
     variation       574
                     /replace="s"
                     /db_xref="dbSNP:2292245"
     variation       575
                     /replace="*"
                     /db_xref="dbSNP:755909193"
     variation       575
                     /replace="e"
                     /db_xref="dbSNP:1474492320"
     variation       577
                     /replace="t"
                     /db_xref="dbSNP:780045758"
     variation       578
                     /replace="a"
                     /db_xref="dbSNP:768717099"
     variation       578
                     /replace="e"
                     /db_xref="dbSNP:773937538"
     variation       578
                     /replace="k"
                     /db_xref="dbSNP:749195922"
     variation       579
                     /replace="g"
                     /db_xref="dbSNP:141789888"
     variation       579
                     /replace="k"
                     /db_xref="dbSNP:1217701258"
     variation       583
                     /replace="n"
                     /db_xref="dbSNP:1216408597"
     variation       584
                     /replace="d"
                     /db_xref="dbSNP:376415455"
     variation       584
                     /replace="k"
                     /db_xref="dbSNP:373792754"
     variation       585
                     /replace="r"
                     /db_xref="dbSNP:772888720"
     variation       586
                     /replace="s"
                     /db_xref="dbSNP:200673288"
     variation       587
                     /replace="k"
                     /db_xref="dbSNP:766714894"
     variation       588
                     /replace="s"
                     /db_xref="dbSNP:1201477016"
     variation       591
                     /replace="g"
                     /db_xref="dbSNP:1281301009"
     variation       591
                     /replace="r"
                     /db_xref="dbSNP:777013014"
     variation       592
                     /replace="e"
                     /db_xref="dbSNP:1008934401"
     variation       593
                     /replace="p"
                     /db_xref="dbSNP:759970992"
     variation       593
                     /replace="w"
                     /db_xref="dbSNP:1187818912"
     variation       594
                     /replace="g"
                     /db_xref="dbSNP:899652686"
     variation       595
                     /replace="h"
                     /db_xref="dbSNP:765747440"
     variation       596
                     /replace="k"
                     /db_xref="dbSNP:369979250"
     variation       597
                     /replace="e"
                     /db_xref="dbSNP:1430914942"
     variation       597
                     /replace="k"
                     /db_xref="dbSNP:1359497383"
     variation       598
                     /replace="n"
                     /db_xref="dbSNP:758505732"
     variation       599
                     /replace="r"
                     /db_xref="dbSNP:1457528823"
     variation       601
                     /replace="-"
                     /db_xref="dbSNP:938330862"
     variation       601
                     /replace="e"
                     /db_xref="dbSNP:1056768622"
     variation       603
                     /replace="s"
                     /db_xref="dbSNP:142654692"
     variation       604
                     /replace="k"
                     /db_xref="dbSNP:1433488876"
     variation       606
                     /replace="k"
                     /db_xref="dbSNP:1361397973"
     variation       607
                     /replace="-"
                     /db_xref="dbSNP:756808522"
     variation       608
                     /replace="e"
                     /db_xref="dbSNP:1405579139"
     variation       608
                     /replace="r"
                     /db_xref="dbSNP:1285444177"
     variation       610
                     /replace="e"
                     /db_xref="dbSNP:1321591429"
     variation       610
                     /replace="g"
                     /db_xref="dbSNP:751787277"
     variation       611
                     /replace="l"
                     /db_xref="dbSNP:372453824"
     variation       612
                     /replace="i"
                     /db_xref="dbSNP:749104748"
     variation       613
                     /replace="h"
                     /db_xref="dbSNP:150936656"
     variation       614
                     /replace="p"
                     /db_xref="dbSNP:375771680"
     variation       615
                     /replace="a"
                     /db_xref="dbSNP:771587112"
     variation       615
                     /replace="t"
                     /db_xref="dbSNP:1319580183"
     variation       615
                     /replace="v"
                     /db_xref="dbSNP:748075001"
     variation       616
                     /replace="k"
                     /db_xref="dbSNP:534149617"
     variation       618
                     /replace="q"
                     /db_xref="dbSNP:370618193"
     variation       618
                     /replace="r"
                     /db_xref="dbSNP:558829542"
     variation       618
                     /replace="w"
                     /db_xref="dbSNP:746634839"
     variation       619
                     /replace="k"
                     /db_xref="dbSNP:1346527410"
     variation       621
                     /replace="m"
                     /db_xref="dbSNP:759881134"
     variation       621
                     /replace="t"
                     /db_xref="dbSNP:770214603"
     variation       622
                     /replace="e"
                     /db_xref="dbSNP:570913535"
     variation       625
                     /replace="p"
                     /db_xref="dbSNP:1425385355"
     variation       625
                     /replace="t"
                     /db_xref="dbSNP:868706225"
     variation       626
                     /replace="a"
                     /db_xref="dbSNP:1305025457"
     variation       626
                     /replace="t"
                     /db_xref="dbSNP:1343931422"
     variation       627
                     /replace="a"
                     /db_xref="dbSNP:372086949"
     variation       627
                     /replace="h"
                     /db_xref="dbSNP:1274065240"
     variation       628
                     /replace="a"
                     /db_xref="dbSNP:764187290"
     variation       628
                     /replace="l"
                     /db_xref="dbSNP:751593508"
     variation       628
                     /replace="s"
                     /db_xref="dbSNP:762034027"
     variation       629
                     /replace="t"
                     /db_xref="dbSNP:1352814264"
     variation       630
                     /replace="a"
                     /db_xref="dbSNP:767835013"
     variation       630
                     /replace="p"
                     /db_xref="dbSNP:1293307352"
     variation       631
                     /replace="n"
                     /db_xref="dbSNP:143827266"
     variation       632
                     /replace="s"
                     /db_xref="dbSNP:1197684972"
     variation       634
                     /replace="a"
                     /db_xref="dbSNP:556314095"
     variation       634
                     /replace="t"
                     /db_xref="dbSNP:1233047752"
     variation       635
                     /replace="g"
                     /db_xref="dbSNP:1380294442"
     variation       635
                     /replace="k"
                     /db_xref="dbSNP:377266213"
     variation       638
                     /replace="y"
                     /db_xref="dbSNP:752630823"
     variation       639
                     /replace="*"
                     /db_xref="dbSNP:1243705083"
     variation       639
                     /replace="r"
                     /db_xref="dbSNP:9870460"
     variation       640
                     /replace="s"
                     /db_xref="dbSNP:1363754586"
     variation       641
                     /replace="v"
                     /db_xref="dbSNP:1404794997"
     variation       642
                     /replace="l"
                     /db_xref="dbSNP:1356441306"
     variation       642
                     /replace="s"
                     /db_xref="dbSNP:777272139"
     variation       643
                     /replace="g"
                     /db_xref="dbSNP:1444121461"
     variation       644
                     /replace="r"
                     /db_xref="dbSNP:370839444"
     variation       644
                     /replace="y"
                     /db_xref="dbSNP:149011628"
     variation       645
                     /replace="k"
                     /db_xref="dbSNP:1246594955"
     variation       646
                     /replace="*"
                     /db_xref="dbSNP:1316588621"
     variation       646
                     /replace="r"
                     /db_xref="dbSNP:770486552"
     variation       647
                     /replace="h"
                     /db_xref="dbSNP:542134871"
     variation       648
                     /replace="h"
                     /db_xref="dbSNP:770126442"
     variation       648
                     /replace="r"
                     /db_xref="dbSNP:1332007642"
     variation       649
                     /replace="a"
                     /db_xref="dbSNP:199980261"
     variation       649
                     /replace="i"
                     /db_xref="dbSNP:763479986"
     variation       650
                     /replace="a"
                     /db_xref="dbSNP:774976952"
     variation       650
                     /replace="t"
                     /db_xref="dbSNP:769053896"
     variation       651
                     /replace="f"
                     /db_xref="dbSNP:761975908"
     variation       655
                     /replace="e"
                     /db_xref="dbSNP:140914977"
     variation       655
                     /replace="h"
                     /db_xref="dbSNP:1286692839"
     variation       655
                     /replace="r"
                     /db_xref="dbSNP:760998633"
     variation       656
                     /replace="m"
                     /db_xref="dbSNP:375592915"
     variation       656
                     /replace="t"
                     /db_xref="dbSNP:17634074"
     variation       657
                     /replace="a"
                     /db_xref="dbSNP:370534593"
     variation       657
                     /replace="g"
                     /db_xref="dbSNP:758300826"
     variation       657
                     /replace="s"
                     /db_xref="dbSNP:938407998"
     variation       658
                     /replace="e"
                     /db_xref="dbSNP:751582799"
     variation       658
                     /replace="r"
                     /db_xref="dbSNP:185135949"
     variation       659
                     /replace="k"
                     /db_xref="dbSNP:756731987"
     variation       660
                     /replace="r"
                     /db_xref="dbSNP:780734306"
     variation       662
                     /replace="a"
                     /db_xref="dbSNP:745476190"
     variation       662
                     /replace="t"
                     /db_xref="dbSNP:1338636038"
     variation       662
                     /replace="v"
                     /db_xref="dbSNP:865998414"
     variation       663
                     /replace="s"
                     /db_xref="dbSNP:769470149"
     variation       666
                     /replace="l"
                     /db_xref="dbSNP:114711614"
     variation       666
                     /replace="p"
                     /db_xref="dbSNP:749600695"
     variation       667
                     /replace="d"
                     /db_xref="dbSNP:774685431"
     variation       667
                     /replace="n"
                     /db_xref="dbSNP:769127105"
     variation       668
                     /replace="p"
                     /db_xref="dbSNP:748713152"
     variation       669
                     /replace="d"
                     /db_xref="dbSNP:773455165"
     variation       669
                     /replace="n"
                     /db_xref="dbSNP:149537126"
     variation       670
                     /replace="i"
                     /db_xref="dbSNP:1442351334"
     variation       671
                     /replace="g"
                     /db_xref="dbSNP:1194070424"
     variation       672
                     /replace="i"
                     /db_xref="dbSNP:760912149"
     variation       673
                     /replace="s"
                     /db_xref="dbSNP:1474573057"
     variation       674
                     /replace="i"
                     /db_xref="dbSNP:766524191"
     variation       676
                     /replace="v"
                     /db_xref="dbSNP:1430188274"
     variation       677
                     /replace="l"
                     /db_xref="dbSNP:377217452"
     variation       677
                     /replace="s"
                     /db_xref="dbSNP:776971532"
     variation       678
                     /replace="l"
                     /db_xref="dbSNP:763990193"
     variation       678
                     /replace="p"
                     /db_xref="dbSNP:751479834"
     variation       678
                     /replace="t"
                     /db_xref="dbSNP:1400052895"
     variation       679
                     /replace="t"
                     /db_xref="dbSNP:561879723"
     variation       680
                     /replace="s"
                     /db_xref="dbSNP:766977146"
     variation       683
                     /replace="k"
                     /db_xref="dbSNP:1277199407"
     variation       684
                     /replace="q"
                     /db_xref="dbSNP:997571527"
     variation       685
                     /replace="c"
                     /db_xref="dbSNP:1323720931"
     variation       685
                     /replace="y"
                     /db_xref="dbSNP:1225814845"
     variation       686
                     /replace="a"
                     /db_xref="dbSNP:1206205974"
     variation       686
                     /replace="g"
                     /db_xref="dbSNP:375290064"
     variation       686
                     /replace="t"
                     /db_xref="dbSNP:749942817"
     variation       687
                     /replace="r"
                     /db_xref="dbSNP:755675267"
     variation       691
                     /replace="e"
                     /db_xref="dbSNP:779565881"
     variation       691
                     /replace="m"
                     /db_xref="dbSNP:749006063"
     variation       692
                     /replace="g"
                     /db_xref="dbSNP:1487754734"
     variation       693
                     /replace="p"
                     /db_xref="dbSNP:201045391"
     variation       694
                     /replace="*"
                     /db_xref="dbSNP:748623403"
     variation       696
                     /replace="p"
                     /db_xref="dbSNP:1255295995"
     variation       697
                     /replace="c"
                     /db_xref="dbSNP:1481533929"
     variation       697
                     /replace="s"
                     /db_xref="dbSNP:1422842312"
     variation       698
                     /replace="e"
                     /db_xref="dbSNP:1201378578"
     variation       698
                     /replace="k"
                     /db_xref="dbSNP:773369390"
     variation       699
                     /replace="n"
                     /db_xref="dbSNP:747074079"
     variation       700
                     /replace="p"
                     /db_xref="dbSNP:1010272533"
     variation       700
                     /replace="r"
                     /db_xref="dbSNP:771110561"
     variation       701
                     /replace="t"
                     /db_xref="dbSNP:1386973409"
     variation       701
                     /replace="v"
                     /db_xref="dbSNP:144097791"
     variation       702
                     /replace="s"
                     /db_xref="dbSNP:920763669"
     variation       703
                     /replace="c"
                     /db_xref="dbSNP:1417328865"
     variation       703
                     /replace="h"
                     /db_xref="dbSNP:147345951"
     variation       703
                     /replace="r"
                     /db_xref="dbSNP:371158794"
     variation       704
                     /replace="r"
                     /db_xref="dbSNP:565961396"
     variation       705
                     /replace="d"
                     /db_xref="dbSNP:1443257095"
     variation       705
                     /replace="y"
                     /db_xref="dbSNP:750425296"
     variation       706
                     /replace="q"
                     /db_xref="dbSNP:753382729"
     variation       706
                     /replace="r"
                     /db_xref="dbSNP:527722149"
     variation       706
                     /replace="r"
                     /db_xref="dbSNP:755543733"
     variation       707
                     /replace="l"
                     /db_xref="dbSNP:1263394229"
     variation       708
                     /replace="s"
                     /db_xref="dbSNP:1195610540"
     variation       709
                     /replace="a"
                     /db_xref="dbSNP:188968913"
     variation       710
                     /replace="d"
                     /db_xref="dbSNP:944687033"
     variation       712
                     /replace="k"
                     /db_xref="dbSNP:779078391"
     variation       714
                     /replace="t"
                     /db_xref="dbSNP:748535428"
     variation       716
                     /replace="v"
                     /db_xref="dbSNP:758892699"
     variation       719
                     /replace="a"
                     /db_xref="dbSNP:771802509"
     variation       719
                     /replace="v"
                     /db_xref="dbSNP:139598050"
     variation       720
                     /replace="e"
                     /db_xref="dbSNP:1308356820"
     variation       720
                     /replace="g"
                     /db_xref="dbSNP:1312081657"
     variation       721
                     /replace="e"
                     /db_xref="dbSNP:1229850295"
     variation       722
                     /replace="t"
                     /db_xref="dbSNP:869306841"
     variation       723
                     /replace="t"
                     /db_xref="dbSNP:1256352434"
     variation       724
                     /replace="f"
                     /db_xref="dbSNP:773021074"
     variation       727
                     /replace="v"
                     /db_xref="dbSNP:147936383"
     variation       729
                     /replace="c"
                     /db_xref="dbSNP:770912567"
     variation       729
                     /replace="h"
                     /db_xref="dbSNP:544447280"
     variation       731
                     /replace="a"
                     /db_xref="dbSNP:759084202"
     variation       732
                     /replace="p"
                     /db_xref="dbSNP:764881823"
     variation       732
                     /replace="s"
                     /db_xref="dbSNP:267599923"
     variation       733
                     /replace="r"
                     /db_xref="dbSNP:752376773"
     variation       734
                     /replace="k"
                     /db_xref="dbSNP:1055688775"
     variation       735
                     /replace="l"
                     /db_xref="dbSNP:368331411"
     variation       737
                     /replace="r"
                     /db_xref="dbSNP:1227717081"
     variation       738
                     /replace="i"
                     /db_xref="dbSNP:1465434017"
     variation       739
                     /replace="i"
                     /db_xref="dbSNP:764516051"
     variation       742
                     /replace="i"
                     /db_xref="dbSNP:757650773"
     variation       742
                     /replace="t"
                     /db_xref="dbSNP:751960907"
     variation       744
                     /replace="v"
                     /db_xref="dbSNP:1446435610"
     variation       745
                     /replace="a"
                     /db_xref="dbSNP:563098089"
     variation       745
                     /replace="s"
                     /db_xref="dbSNP:1035737603"
     variation       746
                     /replace="a"
                     /db_xref="dbSNP:371119194"
     variation       746
                     /replace="t"
                     /db_xref="dbSNP:1332316958"
     variation       746
                     /replace="v"
                     /db_xref="dbSNP:780126620"
     variation       748
                     /replace="s"
                     /db_xref="dbSNP:1383946725"
     variation       748
                     /replace="t"
                     /db_xref="dbSNP:749468913"
     variation       749
                     /replace="f"
                     /db_xref="dbSNP:376160752"
     variation       750
                     /replace="l"
                     /db_xref="dbSNP:777373171"
     variation       750
                     /replace="v"
                     /db_xref="dbSNP:150064339"
     variation       751
                     /replace="f"
                     /db_xref="dbSNP:145016700"
     variation       752
                     /replace="v"
                     /db_xref="dbSNP:919959614"
     variation       753
                     /replace="i"
                     /db_xref="dbSNP:1255286324"
     variation       753
                     /replace="v"
                     /db_xref="dbSNP:776600575"
     variation       754
                     /replace="f"
                     /db_xref="dbSNP:569625974"
     variation       755
                     /replace="v"
                     /db_xref="dbSNP:769381581"
     variation       756
                     /replace="s"
                     /db_xref="dbSNP:775174393"
     variation       758
                     /replace="m"
                     /db_xref="dbSNP:1477284894"
     variation       759
                     /replace="l"
                     /db_xref="dbSNP:537359013"
     variation       760
                     /replace="i"
                     /db_xref="dbSNP:763857433"
     variation       762
                     /replace="r"
                     /db_xref="dbSNP:985370289"
     variation       764
                     /replace="k"
                     /db_xref="dbSNP:1202738525"
     variation       765
                     /replace="c"
                     /db_xref="dbSNP:1277064197"
     variation       765
                     /replace="y"
                     /db_xref="dbSNP:913593338"
     variation       767
                     /replace="h"
                     /db_xref="dbSNP:755945049"
     variation       769
                     /replace="v"
                     /db_xref="dbSNP:1193907254"
     variation       770
                     /replace="l"
                     /db_xref="dbSNP:780013182"
     variation       772
                     /replace="y"
                     /db_xref="dbSNP:141754618"
     variation       773
                     /replace="v"
                     /db_xref="dbSNP:76001191"
     variation       774
                     /replace="*"
                     /db_xref="dbSNP:1422619781"
     variation       775
                     /replace="e"
                     /db_xref="dbSNP:1478203908"
     variation       776
                     /replace="s"
                     /db_xref="dbSNP:1174258586"
     variation       777
                     /replace="i"
                     /db_xref="dbSNP:1399890439"
     variation       777
                     /replace="s"
                     /db_xref="dbSNP:1413474883"
     variation       779
                     /replace="s"
                     /db_xref="dbSNP:778426588"
     variation       780
                     /replace="l"
                     /db_xref="dbSNP:777372586"
     variation       780
                     /replace="r"
                     /db_xref="dbSNP:1284884442"
     variation       780
                     /replace="r"
                     /db_xref="dbSNP:747596725"
     variation       781
                     /replace="l"
                     /db_xref="dbSNP:1277138337"
     variation       782
                     /replace="f"
                     /db_xref="dbSNP:746713297"
     variation       782
                     /replace="v"
                     /db_xref="dbSNP:771236544"
     variation       783
                     /replace="r"
                     /db_xref="dbSNP:757797762"
     variation       784
                     /replace="d"
                     /db_xref="dbSNP:777357131"
     variation       784
                     /replace="k"
                     /db_xref="dbSNP:969539204"
     variation       784
                     /replace="s"
                     /db_xref="dbSNP:1344923990"
     variation       785
                     /replace="g"
                     /db_xref="dbSNP:1235846070"
     variation       786
                     /replace="g"
                     /db_xref="dbSNP:1435089215"
     variation       786
                     /replace="n"
                     /db_xref="dbSNP:1205855425"
     variation       787
                     /replace="i"
                     /db_xref="dbSNP:1352882"
     variation       787
                     /replace="t"
                     /db_xref="dbSNP:1421985286"
     variation       788
                     /replace="l"
                     /db_xref="dbSNP:1193371233"
     variation       788
                     /replace="s"
                     /db_xref="dbSNP:760022654"
     variation       789
                     /replace="i"
                     /db_xref="dbSNP:1209278907"
     variation       789
                     /replace="l"
                     /db_xref="dbSNP:770219135"
     variation       790
                     /replace="-"
                     /db_xref="dbSNP:1365411613"
     variation       792
                     /replace="v"
                     /db_xref="dbSNP:776124375"
     variation       793
                     /replace="l"
                     /db_xref="dbSNP:538902396"
     variation       793
                     /replace="p"
                     /db_xref="dbSNP:1200723021"
     variation       794
                     /replace="g"
                     /db_xref="dbSNP:1157524558"
     variation       794
                     /replace="n"
                     /db_xref="dbSNP:1375915929"
     variation       795
                     /replace="e"
                     /db_xref="dbSNP:1368745139"
     variation       796
                     /replace="i"
                     /db_xref="dbSNP:548221148"
     variation       796
                     /replace="k"
                     /db_xref="dbSNP:1459104836"
     variation       798
                     /replace="p"
                     /db_xref="dbSNP:375366467"
     variation       799
                     /replace="s"
                     /db_xref="dbSNP:993503700"
     variation       800
                     /replace="p"
                     /db_xref="dbSNP:762065735"
     variation       800
                     /replace="t"
                     /db_xref="dbSNP:1333954965"
     variation       801
                     /replace="f"
                     /db_xref="dbSNP:1279990571"
     variation       801
                     /replace="v"
                     /db_xref="dbSNP:767836750"
     variation       803
                     /replace="e"
                     /db_xref="dbSNP:773548210"
     variation       803
                     /replace="h"
                     /db_xref="dbSNP:757504918"
     variation       803
                     /replace="r"
                     /db_xref="dbSNP:201604042"
     variation       804
                     /replace="f"
                     /db_xref="dbSNP:1242919892"
     variation       805
                     /replace="f"
                     /db_xref="dbSNP:1403669311"
     variation       807
                     /replace="h"
                     /db_xref="dbSNP:1265032458"
     variation       808
                     /replace="i"
                     /db_xref="dbSNP:138568998"
     variation       808
                     /replace="s"
                     /db_xref="dbSNP:765128415"
     variation       808
                     /replace="v"
                     /db_xref="dbSNP:1217454558"
     variation       809
                     /replace="s"
                     /db_xref="dbSNP:72878145"
     variation       812
                     /replace="c"
                     /db_xref="dbSNP:751085237"
     variation       812
                     /replace="y"
                     /db_xref="dbSNP:781622967"
     variation       815
                     /replace="i"
                     /db_xref="dbSNP:756821576"
     variation       815
                     /replace="k"
                     /db_xref="dbSNP:570891194"
     variation       816
                     /replace="h"
                     /db_xref="dbSNP:538463283"
     variation       817
                     /replace="y"
                     /db_xref="dbSNP:556748617"
     Region          818..1089
                     /region_name="PTPc"
                     /note="Protein tyrosine phosphatase, catalytic domain;
                     smart00194"
                     /db_xref="CDD:214550"
     variation       818
                     /replace="g"
                     /db_xref="dbSNP:749688474"
     variation       818
                     /replace="r"
                     /db_xref="dbSNP:1466527868"
     variation       818
                     /replace="v"
                     /db_xref="dbSNP:1412107685"
     variation       819
                     /replace="f"
                     /db_xref="dbSNP:1398798295"
     variation       821
                     /replace="g"
                     /db_xref="dbSNP:769297593"
     variation       821
                     /replace="k"
                     /db_xref="dbSNP:1465533579"
     variation       823
                     /replace="s"
                     /db_xref="dbSNP:775053702"
     variation       826
                     /replace="-"
                     /db_xref="dbSNP:753317909"
     variation       826
                     /replace="a"
                     /db_xref="dbSNP:866407677"
     variation       826
                     /replace="i"
                     /db_xref="dbSNP:1402049795"
     variation       828
                     /replace="c"
                     /db_xref="dbSNP:780222251"
     variation       828
                     /replace="h"
                     /db_xref="dbSNP:561653746"
     variation       829
                     /replace="c"
                     /db_xref="dbSNP:779529850"
     variation       829
                     /replace="r"
                     /db_xref="dbSNP:755457953"
     variation       830
                     /replace="s"
                     /db_xref="dbSNP:369989465"
     variation       831
                     /replace="t"
                     /db_xref="dbSNP:990260018"
     variation       832
                     /replace="n"
                     /db_xref="dbSNP:772229285"
     variation       833
                     /replace="r"
                     /db_xref="dbSNP:141106066"
     variation       833
                     /replace="v"
                     /db_xref="dbSNP:777940130"
     variation       834
                     /replace="s"
                     /db_xref="dbSNP:747134653"
     variation       835
                     /replace="f"
                     /db_xref="dbSNP:146787787"
     variation       836
                     /replace="a"
                     /db_xref="dbSNP:776777876"
     variation       836
                     /replace="t"
                     /db_xref="dbSNP:769164807"
     variation       837
                     /replace="t"
                     /db_xref="dbSNP:1427937327"
     variation       837
                     /replace="v"
                     /db_xref="dbSNP:1431924650"
     variation       838
                     /replace="e"
                     /db_xref="dbSNP:768482375"
     variation       839
                     /replace="y"
                     /db_xref="dbSNP:1381039545"
     variation       841
                     /replace="s"
                     /db_xref="dbSNP:774939402"
     variation       843
                     /replace="l"
                     /db_xref="dbSNP:1296600003"
     variation       844
                     /replace="a"
                     /db_xref="dbSNP:1429836077"
     variation       844
                     /replace="k"
                     /db_xref="dbSNP:1360123939"
     Region          847..1089
                     /region_name="PTPc"
                     /note="Protein tyrosine phosphatases (PTP) catalyze the
                     dephosphorylation of phosphotyrosine peptides; they
                     regulate phosphotyrosine levels in signal transduction
                     pathways. The depth of the active site cleft renders the
                     enzyme specific for phosphorylated Tyr...; cd00047"
                     /db_xref="CDD:238006"
     variation       847
                     /replace="q"
                     /db_xref="dbSNP:1329093214"
     variation       848
                     /replace="t"
                     /db_xref="dbSNP:761765590"
     variation       849
                     /replace="h"
                     /db_xref="dbSNP:1337330092"
     variation       849
                     /replace="n"
                     /db_xref="dbSNP:145287841"
     variation       851
                     /replace="*"
                     /db_xref="dbSNP:1217436136"
     variation       851
                     /replace="h"
                     /db_xref="dbSNP:1382713099"
     variation       852
                     /replace="m"
                     /db_xref="dbSNP:560538325"
     variation       852
                     /replace="v"
                     /db_xref="dbSNP:749958580"
     variation       853
                     /replace="h"
                     /db_xref="dbSNP:760158363"
     variation       853
                     /replace="s"
                     /db_xref="dbSNP:373482559"
     variation       856
                     /replace="v"
                     /db_xref="dbSNP:1241596850"
     variation       857
                     /replace="f"
                     /db_xref="dbSNP:760198568"
     variation       857
                     /replace="h"
                     /db_xref="dbSNP:556570148"
     variation       857
                     /replace="y"
                     /db_xref="dbSNP:1311635157"
     variation       859
                     /replace="y"
                     /db_xref="dbSNP:765854984"
     variation       860
                     /replace="g"
                     /db_xref="dbSNP:149158341"
     variation       860
                     /replace="n"
                     /db_xref="dbSNP:1388647049"
     variation       866
                     /replace="h"
                     /db_xref="dbSNP:753126519"
     variation       866
                     /replace="s"
                     /db_xref="dbSNP:759292865"
     variation       867
                     /replace="-"
                     /db_xref="dbSNP:1461000109"
     variation       867
                     /replace="l"
                     /db_xref="dbSNP:1467094762"
     variation       867
                     /replace="s"
                     /db_xref="dbSNP:1326726248"
     variation       868
                     /replace="s"
                     /db_xref="dbSNP:199631360"
     variation       869
                     /replace="r"
                     /db_xref="dbSNP:758748337"
     variation       870
                     /replace="n"
                     /db_xref="dbSNP:764659539"
     variation       870
                     /replace="r"
                     /db_xref="dbSNP:1285603386"
     variation       872
                     /replace="s"
                     /db_xref="dbSNP:370108297"
     variation       873
                     /replace="m"
                     /db_xref="dbSNP:752048163"
     variation       873
                     /replace="n"
                     /db_xref="dbSNP:757340112"
     variation       875
                     /replace="s"
                     /db_xref="dbSNP:781276396"
     variation       876
                     /replace="e"
                     /db_xref="dbSNP:1272850764"
     variation       876
                     /replace="n"
                     /db_xref="dbSNP:200045412"
     variation       878
                     /replace="i"
                     /db_xref="dbSNP:1212331392"
     variation       878
                     /replace="v"
                     /db_xref="dbSNP:1443077220"
     variation       879
                     /replace="n"
                     /db_xref="dbSNP:61754216"
     variation       881
                     /replace="d"
                     /db_xref="dbSNP:1325038488"
     variation       883
                     /replace="i"
                     /db_xref="dbSNP:747929817"
     variation       884
                     /replace="-"
                     /db_xref="dbSNP:778645613"
     variation       884
                     /replace="d"
                     /db_xref="dbSNP:562571992"
     variation       884
                     /replace="g"
                     /db_xref="dbSNP:1187008638"
     variation       884
                     /replace="h"
                     /db_xref="dbSNP:1176133299"
     variation       886
                     /replace="c"
                     /db_xref="dbSNP:1332218905"
     variation       887
                     /replace="s"
                     /db_xref="dbSNP:146998290"
     variation       889
                     /replace="v"
                     /db_xref="dbSNP:1301819403"
     variation       890
                     /replace="n"
                     /db_xref="dbSNP:1347263829"
     variation       890
                     /replace="t"
                     /db_xref="dbSNP:1312902791"
     variation       891
                     /replace="a"
                     /db_xref="dbSNP:756229616"
     variation       891
                     /replace="t"
                     /db_xref="dbSNP:750484232"
     variation       892
                     /replace="f"
                     /db_xref="dbSNP:780253886"
     variation       893
                     /replace="t"
                     /db_xref="dbSNP:1260809858"
     variation       893
                     /replace="v"
                     /db_xref="dbSNP:749533253"
     variation       894
                     /replace="g"
                     /db_xref="dbSNP:1451915749"
     variation       895
                     /replace="t"
                     /db_xref="dbSNP:758155993"
     variation       896
                     /replace="*"
                     /db_xref="dbSNP:1474365706"
     variation       896
                     /replace="h"
                     /db_xref="dbSNP:1250987327"
     variation       898
                     /replace="p"
                     /db_xref="dbSNP:1453337781"
     variation       899
                     /replace="l"
                     /db_xref="dbSNP:746925271"
     variation       900
                     /replace="k"
                     /db_xref="dbSNP:201105086"
     variation       903
                     /replace="l"
                     /db_xref="dbSNP:776757908"
     variation       905
                     /replace="d"
                     /db_xref="dbSNP:138952511"
     variation       906
                     /replace="l"
                     /db_xref="dbSNP:147139816"
     variation       907
                     /replace="s"
                     /db_xref="dbSNP:139531452"
     variation       908
                     /replace="k"
                     /db_xref="dbSNP:1407377338"
     variation       908
                     /replace="r"
                     /db_xref="dbSNP:775266617"
     variation       909
                     /replace="t"
                     /db_xref="dbSNP:1324479089"
     variation       910
                     /replace="i"
                     /db_xref="dbSNP:1370907616"
     variation       910
                     /replace="v"
                     /db_xref="dbSNP:1161448846"
     variation       912
                     /replace="d"
                     /db_xref="dbSNP:768996041"
     variation       912
                     /replace="g"
                     /db_xref="dbSNP:1447692221"
     variation       913
                     /replace="e"
                     /db_xref="dbSNP:748515917"
     variation       915
                     /replace="s"
                     /db_xref="dbSNP:1189834312"
     variation       917
                     /replace="i"
                     /db_xref="dbSNP:767985325"
     variation       917
                     /replace="t"
                     /db_xref="dbSNP:762291087"
     variation       918
                     /replace="i"
                     /db_xref="dbSNP:1272989730"
     variation       919
                     /replace="h"
                     /db_xref="dbSNP:1438091311"
     variation       920
                     /replace="l"
                     /db_xref="dbSNP:1356789172"
     variation       920
                     /replace="t"
                     /db_xref="dbSNP:1237856610"
     variation       921
                     /replace="f"
                     /db_xref="dbSNP:1215328140"
     variation       922
                     /replace="m"
                     /db_xref="dbSNP:1271256949"
     variation       922
                     /replace="t"
                     /db_xref="dbSNP:557054933"
     variation       924
                     /replace="f"
                     /db_xref="dbSNP:973587462"
     variation       925
                     /replace="l"
                     /db_xref="dbSNP:760733357"
     variation       925
                     /replace="v"
                     /db_xref="dbSNP:766463548"
     variation       927
                     /replace="t"
                     /db_xref="dbSNP:754027035"
     variation       930
                     /replace="q"
                     /db_xref="dbSNP:1303476542"
     variation       930
                     /replace="r"
                     /db_xref="dbSNP:1028368537"
     variation       930
                     /replace="r"
                     /db_xref="dbSNP:757929199"
     variation       933
                     /replace="h"
                     /db_xref="dbSNP:765346594"
     variation       935
                     /replace="y"
                     /db_xref="dbSNP:371427951"
     variation       936
                     /replace="s"
                     /db_xref="dbSNP:1433179926"
     variation       937
                     /replace="p"
                     /db_xref="dbSNP:1312450207"
     variation       938
                     /replace="a"
                     /db_xref="dbSNP:1354596223"
     variation       938
                     /replace="i"
                     /db_xref="dbSNP:767871302"
     variation       938
                     /replace="t"
                     /db_xref="dbSNP:978454224"
     variation       939
                     /replace="g"
                     /db_xref="dbSNP:1297722074"
     variation       942
                     /replace="d"
                     /db_xref="dbSNP:757104154"
     variation       942
                     /replace="k"
                     /db_xref="dbSNP:1305682965"
     variation       943
                     /replace="e"
                     /db_xref="dbSNP:781145753"
     variation       943
                     /replace="k"
                     /db_xref="dbSNP:1296472162"
     variation       944
                     /replace="y"
                     /db_xref="dbSNP:1486336529"
     variation       948
                     /replace="t"
                     /db_xref="dbSNP:145097172"
     variation       950
                     /replace="m"
                     /db_xref="dbSNP:201115216"
     variation       950
                     /replace="t"
                     /db_xref="dbSNP:143908630"
     variation       951
                     /replace="l"
                     /db_xref="dbSNP:988937771"
     variation       952
                     /replace="k"
                     /db_xref="dbSNP:748720691"
     variation       952
                     /replace="r"
                     /db_xref="dbSNP:1418049297"
     variation       954
                     /replace="r"
                     /db_xref="dbSNP:1428408763"
     variation       955
                     /replace="q"
                     /db_xref="dbSNP:917515083"
     variation       957
                     /replace="r"
                     /db_xref="dbSNP:1177374965"
     variation       959
                     /replace="c"
                     /db_xref="dbSNP:566944160"
     variation       960
                     /replace="y"
                     /db_xref="dbSNP:747814396"
     variation       961
                     /replace="n"
                     /db_xref="dbSNP:1335953469"
     variation       961
                     /replace="p"
                     /db_xref="dbSNP:750853728"
     variation       961
                     /replace="t"
                     /db_xref="dbSNP:1476171059"
     variation       963
                     /replace="c"
                     /db_xref="dbSNP:772358512"
     variation       963
                     /replace="h"
                     /db_xref="dbSNP:773599761"
     variation       964
                     /replace="c"
                     /db_xref="dbSNP:747467108"
     variation       964
                     /replace="h"
                     /db_xref="dbSNP:771320696"
     variation       967
                     /replace="i"
                     /db_xref="dbSNP:139755568"
     variation       967
                     /replace="v"
                     /db_xref="dbSNP:1485858671"
     variation       969
                     /replace="y"
                     /db_xref="dbSNP:759529074"
     variation       970
                     /replace="i"
                     /db_xref="dbSNP:765414225"
     variation       972
                     /replace="e"
                     /db_xref="dbSNP:1349419709"
     variation       972
                     /replace="v"
                     /db_xref="dbSNP:763270072"
     variation       975
                     /replace="c"
                     /db_xref="dbSNP:1471174952"
     variation       982
                     /replace="a"
                     /db_xref="dbSNP:763215260"
     variation       983
                     /replace="-"
                     /db_xref="dbSNP:759534887"
     variation       983
                     /replace="h"
                     /db_xref="dbSNP:764384969"
     variation       984
                     /replace="q"
                     /db_xref="dbSNP:955517142"
     variation       986
                     /replace="q"
                     /db_xref="dbSNP:774785758"
     variation       987
                     /replace="r"
                     /db_xref="dbSNP:1459838328"
     variation       988
                     /replace="a"
                     /db_xref="dbSNP:1400407660"
     variation       988
                     /replace="i"
                     /db_xref="dbSNP:1325083115"
     variation       989
                     /replace="v"
                     /db_xref="dbSNP:760536348"
     variation       990
                     /replace="s"
                     /db_xref="dbSNP:766212078"
     variation       991
                     /replace="k"
                     /db_xref="dbSNP:753654008"
     variation       993
                     /replace="h"
                     /db_xref="dbSNP:1035893377"
     variation       994
                     /replace="y"
                     /db_xref="dbSNP:754976006"
     variation       996
                     /replace="e"
                     /db_xref="dbSNP:151031619"
     variation       997
                     /replace="r"
                     /db_xref="dbSNP:1333081792"
     variation       998
                     /replace="s"
                     /db_xref="dbSNP:752181711"
     Site            order(999,1030..1031,1034,1037..1038)
                     /site_type="active"
                     /db_xref="CDD:238006"
     variation       999
                     /replace="d"
                     /db_xref="dbSNP:777397652"
     variation       999
                     /replace="v"
                     /db_xref="dbSNP:757944074"
     variation       1000
                     /replace="i"
                     /db_xref="dbSNP:1472150314"
     variation       1000
                     /replace="t"
                     /db_xref="dbSNP:1016170246"
     variation       1001
                     /replace="g"
                     /db_xref="dbSNP:1232566528"
     variation       1001
                     /replace="r"
                     /db_xref="dbSNP:1202524817"
     variation       1003
                     /replace="p"
                     /db_xref="dbSNP:963079180"
     variation       1003
                     /replace="t"
                     /db_xref="dbSNP:1316676757"
     variation       1004
                     /replace="e"
                     /db_xref="dbSNP:1419800212"
     variation       1004
                     /replace="k"
                     /db_xref="dbSNP:751271092"
     variation       1005
                     /replace="h"
                     /db_xref="dbSNP:1219251468"
     variation       1006
                     /replace="a"
                     /db_xref="dbSNP:1474065513"
     variation       1007
                     /replace="v"
                     /db_xref="dbSNP:757504779"
     variation       1008
                     /replace="s"
                     /db_xref="dbSNP:1420124322"
     variation       1009
                     /replace="l"
                     /db_xref="dbSNP:1411217619"
     variation       1010
                     /replace="l"
                     /db_xref="dbSNP:1246183120"
     variation       1010
                     /replace="l"
                     /db_xref="dbSNP:968046324"
     variation       1010
                     /replace="p"
                     /db_xref="dbSNP:913861646"
     variation       1011
                     /replace="s"
                     /db_xref="dbSNP:373945707"
     variation       1012
                     /replace="f"
                     /db_xref="dbSNP:746317242"
     variation       1013
                     /replace="l"
                     /db_xref="dbSNP:770354333"
     variation       1013
                     /replace="v"
                     /db_xref="dbSNP:979316747"
     variation       1015
                     /replace="r"
                     /db_xref="dbSNP:749343865"
     variation       1017
                     /replace="l"
                     /db_xref="dbSNP:768919412"
     variation       1020
                     /replace="q"
                     /db_xref="dbSNP:150212631"
     variation       1020
                     /replace="r"
                     /db_xref="dbSNP:770595135"
     variation       1020
                     /replace="w"
                     /db_xref="dbSNP:774661298"
     variation       1021
                     /replace="v"
                     /db_xref="dbSNP:146981409"
     variation       1022
                     /replace="s"
                     /db_xref="dbSNP:987673426"
     variation       1023
                     /replace="a"
                     /db_xref="dbSNP:371664428"
     variation       1024
                     /replace="m"
                     /db_xref="dbSNP:759300125"
     variation       1024
                     /replace="t"
                     /db_xref="dbSNP:1213298533"
     variation       1025
                     /replace="g"
                     /db_xref="dbSNP:1255599331"
     variation       1026
                     /replace="l"
                     /db_xref="dbSNP:1456476738"
     variation       1027
                     /replace="l"
                     /db_xref="dbSNP:758025953"
     variation       1027
                     /replace="v"
                     /db_xref="dbSNP:1484601331"
     variation       1028
                     /replace="v"
                     /db_xref="dbSNP:765127741"
     variation       1029
                     /replace="v"
                     /db_xref="dbSNP:1242673849"
     variation       1030
                     /replace="h"
                     /db_xref="dbSNP:1161167542"
     variation       1030
                     /replace="r"
                     /db_xref="dbSNP:1476337922"
     variation       1031
                     /replace="g"
                     /db_xref="dbSNP:1431645854"
     variation       1031
                     /replace="w"
                     /db_xref="dbSNP:752698918"
     variation       1032
                     /replace="t"
                     /db_xref="dbSNP:1424804575"
     variation       1035
                     /replace="m"
                     /db_xref="dbSNP:762879857"
     variation       1039
                     /replace="d"
                     /db_xref="dbSNP:1240065134"
     variation       1040
                     /replace="i"
                     /db_xref="dbSNP:1480877811"
     variation       1041
                     /replace="c"
                     /db_xref="dbSNP:751100016"
     variation       1041
                     /replace="h"
                     /db_xref="dbSNP:763554450"
     variation       1042
                     /replace="i"
                     /db_xref="dbSNP:1468845694"
     variation       1042
                     /replace="t"
                     /db_xref="dbSNP:767162414"
     variation       1042
                     /replace="v"
                     /db_xref="dbSNP:138240632"
     variation       1043
                     /replace="l"
                     /db_xref="dbSNP:750106141"
     variation       1045
                     /replace="d"
                     /db_xref="dbSNP:756493450"
     variation       1047
                     /replace="i"
                     /db_xref="dbSNP:900207886"
     variation       1051
                     /replace="i"
                     /db_xref="dbSNP:766859182"
     variation       1052
                     /replace="n"
                     /db_xref="dbSNP:754359256"
     variation       1053
                     /replace="d"
                     /db_xref="dbSNP:759422076"
     variation       1053
                     /replace="h"
                     /db_xref="dbSNP:755567278"
     variation       1056
                     /replace="i"
                     /db_xref="dbSNP:1293721306"
     variation       1058
                     /replace="n"
                     /db_xref="dbSNP:779613788"
     variation       1059
                     /replace="f"
                     /db_xref="dbSNP:148186037"
     variation       1062
                     /replace="i"
                     /db_xref="dbSNP:758474776"
     variation       1063
                     /replace="l"
                     /db_xref="dbSNP:1324418037"
     variation       1063
                     /replace="v"
                     /db_xref="dbSNP:1463493022"
     variation       1065
                     /replace="h"
                     /db_xref="dbSNP:1399201079"
     variation       1065
                     /replace="r"
                     /db_xref="dbSNP:778044422"
     variation       1066
                     /replace="i"
                     /db_xref="dbSNP:375991892"
     variation       1066
                     /replace="v"
                     /db_xref="dbSNP:1292326797"
     variation       1067
                     /replace="r"
                     /db_xref="dbSNP:369150727"
     variation       1069
                     /replace="q"
                     /db_xref="dbSNP:371762103"
     variation       1069
                     /replace="r"
                     /db_xref="dbSNP:902225435"
     variation       1070
                     /replace="c"
                     /db_xref="dbSNP:775293677"
     variation       1070
                     /replace="h"
                     /db_xref="dbSNP:749173201"
     variation       1071
                     /replace="k"
                     /db_xref="dbSNP:1271133768"
     variation       1071
                     /replace="k"
                     /db_xref="dbSNP:775840687"
     variation       1072
                     /replace="c"
                     /db_xref="dbSNP:768556193"
     variation       1073
                     /replace="f"
                     /db_xref="dbSNP:774193514"
     variation       1073
                     /replace="l"
                     /db_xref="dbSNP:1252278315"
     variation       1074
                     /replace="i"
                     /db_xref="dbSNP:1435693144"
     variation       1074
                     /replace="v"
                     /db_xref="dbSNP:1419173085"
     variation       1075
                     /replace="h"
                     /db_xref="dbSNP:761377913"
     variation       1076
                     /replace="s"
                     /db_xref="dbSNP:1419069398"
     variation       1076
                     /replace="t"
                     /db_xref="dbSNP:1476351263"
     variation       1077
                     /replace="k"
                     /db_xref="dbSNP:868037976"
     variation       1079
                     /replace="h"
                     /db_xref="dbSNP:1194598195"
     variation       1079
                     /replace="r"
                     /db_xref="dbSNP:1416433318"
     variation       1083
                     /replace="i"
                     /db_xref="dbSNP:201571277"
     variation       1083
                     /replace="t"
                     /db_xref="dbSNP:766099984"
     variation       1085
                     /replace="n"
                     /db_xref="dbSNP:776496028"
     variation       1086
                     /replace="t"
                     /db_xref="dbSNP:369631162"
     variation       1088
                     /replace="l"
                     /db_xref="dbSNP:1297549575"
     variation       1090
                     /replace="g"
                     /db_xref="dbSNP:1227005967"
     variation       1090
                     /replace="s"
                     /db_xref="dbSNP:759966063"
     variation       1093
                     /replace="v"
                     /db_xref="dbSNP:1284342952"
     variation       1094
                     /replace="k"
                     /db_xref="dbSNP:753180827"
     variation       1094
                     /replace="t"
                     /db_xref="dbSNP:765533974"
     variation       1097
                     /replace="e"
                     /db_xref="dbSNP:1345574389"
     variation       1097
                     /replace="q"
                     /db_xref="dbSNP:764183198"
     variation       1098
                     /replace="l"
                     /db_xref="dbSNP:373896623"
     variation       1098
                     /replace="v"
                     /db_xref="dbSNP:1486361184"
     variation       1099
                     /replace="p"
                     /db_xref="dbSNP:1188818418"
     variation       1099
                     /replace="s"
                     /db_xref="dbSNP:1260246047"
     variation       1101
                     /replace="h"
                     /db_xref="dbSNP:141205324"
     variation       1102
                     /replace="h"
                     /db_xref="dbSNP:781385998"
     variation       1102
                     /replace="r"
                     /db_xref="dbSNP:1372879255"
     variation       1104
                     /replace="h"
                     /db_xref="dbSNP:1397170715"
     variation       1105
                     /replace="n"
                     /db_xref="dbSNP:142191522"
     variation       1106
                     /replace="c"
                     /db_xref="dbSNP:754739666"
     variation       1108
                     /replace="n"
                     /db_xref="dbSNP:778608184"
     variation       1109
                     /replace="g"
                     /db_xref="dbSNP:995982487"
     variation       1109
                     /replace="s"
                     /db_xref="dbSNP:1267132116"
     variation       1110
                     /replace="i"
                     /db_xref="dbSNP:748071937"
     variation       1110
                     /replace="v"
                     /db_xref="dbSNP:1454066103"
     variation       1112
                     /replace="t"
                     /db_xref="dbSNP:377021023"
     variation       1113
                     /replace="p"
                     /db_xref="dbSNP:199720172"
     variation       1113
                     /replace="q"
                     /db_xref="dbSNP:1433760861"
     variation       1115
                     /replace="a"
                     /db_xref="dbSNP:146357666"
     variation       1115
                     /replace="l"
                     /db_xref="dbSNP:1372492634"
     variation       1115
                     /replace="v"
                     /db_xref="dbSNP:776366074"
     variation       1116
                     /replace="e"
                     /db_xref="dbSNP:564946145"
     variation       1116
                     /replace="r"
                     /db_xref="dbSNP:968271861"
     variation       1117
                     /replace="a"
                     /db_xref="dbSNP:770154100"
     variation       1118
                     /replace="k"
                     /db_xref="dbSNP:550927520"
     variation       1120
                     /replace="q"
                     /db_xref="dbSNP:1214811110"
     Region          1121..1379
                     /region_name="PTPc"
                     /note="Protein tyrosine phosphatase, catalytic domain;
                     smart00194"
                     /db_xref="CDD:214550"
     variation       1121
                     /replace="l"
                     /db_xref="dbSNP:368033168"
     variation       1126
                     /replace="k"
                     /db_xref="dbSNP:1190841325"
     variation       1126
                     /replace="m"
                     /db_xref="dbSNP:763422985"
     variation       1127
                     /replace="l"
                     /db_xref="dbSNP:745466795"
     variation       1127
                     /replace="l"
                     /db_xref="dbSNP:780878264"
     variation       1128
                     /replace="a"
                     /db_xref="dbSNP:548790891"
     variation       1129
                     /replace="i"
                     /db_xref="dbSNP:917227252"
     variation       1131
                     /replace="s"
                     /db_xref="dbSNP:1271080628"
     variation       1131
                     /replace="y"
                     /db_xref="dbSNP:775246963"
     variation       1134
                     /replace="k"
                     /db_xref="dbSNP:763219717"
     variation       1135
                     /replace="y"
                     /db_xref="dbSNP:769118812"
     variation       1139
                     /replace="f"
                     /db_xref="dbSNP:774780103"
     variation       1140
                     /replace="i"
                     /db_xref="dbSNP:762309679"
     variation       1141
                     /replace="d"
                     /db_xref="dbSNP:767539324"
     variation       1143
                     /replace="k"
                     /db_xref="dbSNP:370307478"
     variation       1143
                     /replace="t"
                     /db_xref="dbSNP:760853361"
     variation       1144
                     /replace="e"
                     /db_xref="dbSNP:374009338"
     variation       1144
                     /replace="k"
                     /db_xref="dbSNP:1217919993"
     variation       1145
                     /replace="f"
                     /db_xref="dbSNP:1333287106"
     Region          1148..1379
                     /region_name="PTPc"
                     /note="Protein tyrosine phosphatases (PTP) catalyze the
                     dephosphorylation of phosphotyrosine peptides; they
                     regulate phosphotyrosine levels in signal transduction
                     pathways. The depth of the active site cleft renders the
                     enzyme specific for phosphorylated Tyr...; cd00047"
                     /db_xref="CDD:238006"
     variation       1148
                     /replace="d"
                     /db_xref="dbSNP:199721492"
     variation       1148
                     /replace="q"
                     /db_xref="dbSNP:754147699"
     variation       1149
                     /replace="q"
                     /db_xref="dbSNP:763986586"
     variation       1150
                     /replace="k"
                     /db_xref="dbSNP:1251348049"
     variation       1150
                     /replace="s"
                     /db_xref="dbSNP:751501561"
     variation       1151
                     /replace="r"
                     /db_xref="dbSNP:757280326"
     variation       1152
                     /replace="s"
                     /db_xref="dbSNP:781327739"
     variation       1153
                     /replace="s"
                     /db_xref="dbSNP:145207689"
     variation       1154
                     /replace="s"
                     /db_xref="dbSNP:1259590327"
     variation       1155
                     /replace="a"
                     /db_xref="dbSNP:1471783348"
     variation       1157
                     /replace="a"
                     /db_xref="dbSNP:1011607661"
     variation       1158
                     /replace="f"
                     /db_xref="dbSNP:1288015840"
     variation       1159
                     /replace="a"
                     /db_xref="dbSNP:1301446202"
     variation       1159
                     /replace="e"
                     /db_xref="dbSNP:757157623"
     variation       1160
                     /replace="c"
                     /db_xref="dbSNP:759368265"
     variation       1160
                     /replace="h"
                     /db_xref="dbSNP:148705310"
     variation       1161
                     /replace="g"
                     /db_xref="dbSNP:779618365"
     variation       1161
                     /replace="s"
                     /db_xref="dbSNP:755517164"
     variation       1162
                     /replace="l"
                     /db_xref="dbSNP:141644107"
     variation       1164
                     /replace="g"
                     /db_xref="dbSNP:111929965"
     variation       1165
                     /replace="p"
                     /db_xref="dbSNP:754605649"
     variation       1165
                     /replace="v"
                     /db_xref="dbSNP:1454290562"
     variation       1166
                     /replace="e"
                     /db_xref="dbSNP:1375571598"
     variation       1167
                     /replace="l"
                     /db_xref="dbSNP:1001815270"
     variation       1168
                     /replace="f"
                     /db_xref="dbSNP:1159487184"
     variation       1168
                     /replace="l"
                     /db_xref="dbSNP:1477930902"
     variation       1171
                     /replace="t"
                     /db_xref="dbSNP:778581057"
     variation       1172
                     /replace="k"
                     /db_xref="dbSNP:1175315827"
     variation       1173
                     /replace="e"
                     /db_xref="dbSNP:1456144659"
     variation       1174
                     /replace="a"
                     /db_xref="dbSNP:1320392281"
     variation       1175
                     /replace="d"
                     /db_xref="dbSNP:748511741"
     variation       1176
                     /replace="y"
                     /db_xref="dbSNP:772484275"
     variation       1177
                     /replace="m"
                     /db_xref="dbSNP:773535242"
     variation       1177
                     /replace="t"
                     /db_xref="dbSNP:867091015"
     variation       1179
                     /replace="a"
                     /db_xref="dbSNP:747557011"
     variation       1180
                     /replace="f"
                     /db_xref="dbSNP:770877356"
     variation       1181
                     /replace="c"
                     /db_xref="dbSNP:375459395"
     variation       1183
                     /replace="t"
                     /db_xref="dbSNP:1242428575"
     variation       1183
                     /replace="v"
                     /db_xref="dbSNP:1485506890"
     variation       1186
                     /replace="l"
                     /db_xref="dbSNP:1262099019"
     variation       1188
                     /replace="t"
                     /db_xref="dbSNP:1002196000"
     variation       1190
                     /replace="a"
                     /db_xref="dbSNP:770056517"
     variation       1191
                     /replace="c"
                     /db_xref="dbSNP:775794018"
     variation       1191
                     /replace="f"
                     /db_xref="dbSNP:1030356907"
     variation       1192
                     /replace="l"
                     /db_xref="dbSNP:763268118"
     variation       1193
                     /replace="m"
                     /db_xref="dbSNP:1482316642"
     variation       1193
                     /replace="v"
                     /db_xref="dbSNP:771721629"
     variation       1195
                     /replace="r"
                     /db_xref="dbSNP:1181871959"
     variation       1198
                     /replace="l"
                     /db_xref="dbSNP:760430428"
     variation       1198
                     /replace="v"
                     /db_xref="dbSNP:773079610"
     variation       1199
                     /replace="a"
                     /db_xref="dbSNP:766338559"
     variation       1199
                     /replace="q"
                     /db_xref="dbSNP:1462507935"
     variation       1199
                     /replace="r"
                     /db_xref="dbSNP:1258885986"
     variation       1202
                     /replace="m"
                     /db_xref="dbSNP:78612108"
     variation       1202
                     /replace="t"
                     /db_xref="dbSNP:753782144"
     variation       1204
                     /replace="d"
                     /db_xref="dbSNP:1368916817"
     variation       1204
                     /replace="i"
                     /db_xref="dbSNP:781122814"
     variation       1207
                     /replace="*"
                     /db_xref="dbSNP:758989740"
     variation       1207
                     /replace="q"
                     /db_xref="dbSNP:764733284"
     variation       1207
                     /replace="r"
                     /db_xref="dbSNP:752308436"
     variation       1209
                     /replace="i"
                     /db_xref="dbSNP:1416405453"
     variation       1212
                     /replace="q"
                     /db_xref="dbSNP:777338296"
     variation       1212
                     /replace="r"
                     /db_xref="dbSNP:147611132"
     variation       1213
                     /replace="d"
                     /db_xref="dbSNP:1339427844"
     variation       1213
                     /replace="n"
                     /db_xref="dbSNP:375386090"
     variation       1214
                     /replace="t"
                     /db_xref="dbSNP:1276384821"
     variation       1214
                     /replace="v"
                     /db_xref="dbSNP:757628272"
     variation       1216
                     /replace="f"
                     /db_xref="dbSNP:781715107"
     variation       1216
                     /replace="i"
                     /db_xref="dbSNP:746387018"
     variation       1217
                     /replace="m"
                     /db_xref="dbSNP:1199256228"
     variation       1217
                     /replace="t"
                     /db_xref="dbSNP:372467538"
     variation       1218
                     /replace="a"
                     /db_xref="dbSNP:1429241156"
     variation       1218
                     /replace="i"
                     /db_xref="dbSNP:769924756"
     variation       1219
                     /replace="l"
                     /db_xref="dbSNP:780309717"
     variation       1220
                     /replace="c"
                     /db_xref="dbSNP:747871576"
     variation       1221
                     /replace="p"
                     /db_xref="dbSNP:749470447"
     variation       1222
                     /replace="e"
                     /db_xref="dbSNP:768894209"
     variation       1223
                     /replace="r"
                     /db_xref="dbSNP:1406840550"
     variation       1225
                     /replace="c"
                     /db_xref="dbSNP:1474688526"
     variation       1225
                     /replace="n"
                     /db_xref="dbSNP:774507310"
     variation       1226
                     /replace="l"
                     /db_xref="dbSNP:1372974425"
     variation       1227
                     /replace="t"
                     /db_xref="dbSNP:749376552"
     variation       1230
                     /replace="e"
                     /db_xref="dbSNP:755073309"
     variation       1232
                     /replace="m"
                     /db_xref="dbSNP:1328663246"
     variation       1233
                     /replace="y"
                     /db_xref="dbSNP:965910959"
     variation       1235
                     /replace="r"
                     /db_xref="dbSNP:1487640623"
     variation       1235
                     /replace="s"
                     /db_xref="dbSNP:1248721171"
     variation       1237
                     /replace="*"
                     /db_xref="dbSNP:1190788252"
     variation       1237
                     /replace="q"
                     /db_xref="dbSNP:1266408780"
     variation       1238
                     /replace="a"
                     /db_xref="dbSNP:779142973"
     variation       1239
                     /replace="d"
                     /db_xref="dbSNP:1161352190"
     variation       1239
                     /replace="q"
                     /db_xref="dbSNP:978828599"
     variation       1240
                     /replace="s"
                     /db_xref="dbSNP:186734218"
     variation       1241
                     /replace="r"
                     /db_xref="dbSNP:1188884777"
     variation       1242
                     /replace="n"
                     /db_xref="dbSNP:1456297877"
     variation       1242
                     /replace="t"
                     /db_xref="dbSNP:541883131"
     variation       1243
                     /replace="r"
                     /db_xref="dbSNP:1189838103"
     variation       1244
                     /replace="k"
                     /db_xref="dbSNP:1239629138"
     variation       1244
                     /replace="v"
                     /db_xref="dbSNP:1468878314"
     variation       1245
                     /replace="a"
                     /db_xref="dbSNP:1351079405"
     variation       1245
                     /replace="d"
                     /db_xref="dbSNP:201725005"
     variation       1246
                     /replace="c"
                     /db_xref="dbSNP:936487175"
     variation       1247
                     /replace="s"
                     /db_xref="dbSNP:748005942"
     variation       1247
                     /replace="t"
                     /db_xref="dbSNP:776434402"
     variation       1248
                     /replace="i"
                     /db_xref="dbSNP:143489755"
     variation       1249
                     /replace="a"
                     /db_xref="dbSNP:1170862933"
     variation       1251
                     /replace="i"
                     /db_xref="dbSNP:1422047604"
     variation       1252
                     /replace="i"
                     /db_xref="dbSNP:1412062121"
     variation       1253
                     /replace="q"
                     /db_xref="dbSNP:892352709"
     variation       1253
                     /replace="r"
                     /db_xref="dbSNP:1287050407"
     variation       1254
                     /replace="d"
                     /db_xref="dbSNP:1213685387"
     variation       1254
                     /replace="g"
                     /db_xref="dbSNP:1171275719"
     variation       1257
                     /replace="c"
                     /db_xref="dbSNP:1350384895"
     variation       1257
                     /replace="p"
                     /db_xref="dbSNP:1374293936"
     variation       1259
                     /replace="f"
                     /db_xref="dbSNP:769685847"
     variation       1260
                     /replace="s"
                     /db_xref="dbSNP:775471664"
     variation       1263
                     /replace="*"
                     /db_xref="dbSNP:1319929928"
     variation       1264
                     /replace="i"
                     /db_xref="dbSNP:762511464"
     variation       1265
                     /replace="n"
                     /db_xref="dbSNP:763525495"
     variation       1266
                     /replace="s"
                     /db_xref="dbSNP:761400587"
     variation       1267
                     /replace="q"
                     /db_xref="dbSNP:949085314"
     variation       1267
                     /replace="y"
                     /db_xref="dbSNP:1210182962"
     variation       1268
                     /replace="d"
                     /db_xref="dbSNP:750792096"
     variation       1268
                     /replace="g"
                     /db_xref="dbSNP:767941223"
     variation       1269
                     /replace="f"
                     /db_xref="dbSNP:1415349405"
     variation       1269
                     /replace="v"
                     /db_xref="dbSNP:756616317"
     variation       1273
                     /replace="a"
                     /db_xref="dbSNP:150154324"
     variation       1274
                     /replace="a"
                     /db_xref="dbSNP:754317935"
     variation       1274
                     /replace="t"
                     /db_xref="dbSNP:755022934"
     variation       1276
                     /replace="d"
                     /db_xref="dbSNP:200904986"
     variation       1276
                     /replace="v"
                     /db_xref="dbSNP:1403084073"
     variation       1278
                     /replace="y"
                     /db_xref="dbSNP:761066176"
     variation       1279
                     /replace="l"
                     /db_xref="dbSNP:766859118"
     variation       1279
                     /replace="v"
                     /db_xref="dbSNP:13093888"
     variation       1280
                     /replace="s"
                     /db_xref="dbSNP:947365732"
     variation       1283
                     /replace="q"
                     /db_xref="dbSNP:1297131154"
     variation       1283
                     /replace="w"
                     /db_xref="dbSNP:754335459"
     variation       1284
                     /replace="h"
                     /db_xref="dbSNP:373444676"
     variation       1285
                     /replace="f"
                     /db_xref="dbSNP:759984644"
     variation       1286
                     /replace="e"
                     /db_xref="dbSNP:1219559048"
     variation       1286
                     /replace="q"
                     /db_xref="dbSNP:765823872"
     variation       1290
                     /replace="g"
                     /db_xref="dbSNP:754488669"
     Site            order(1292,1321..1322,1325,1328..1329)
                     /site_type="active"
                     /db_xref="CDD:238006"
     variation       1296
                     /replace="p"
                     /db_xref="dbSNP:1209283402"
     variation       1297
                     /replace="l"
                     /db_xref="dbSNP:375595940"
     variation       1299
                     /replace="n"
                     /db_xref="dbSNP:777957147"
     variation       1304
                     /replace="t"
                     /db_xref="dbSNP:199516750"
     variation       1305
                     /replace="n"
                     /db_xref="dbSNP:755840341"
     variation       1305
                     /replace="s"
                     /db_xref="dbSNP:1389163788"
     variation       1306
                     /replace="d"
                     /db_xref="dbSNP:749196641"
     variation       1306
                     /replace="i"
                     /db_xref="dbSNP:1174651225"
     variation       1307
                     /replace="m"
                     /db_xref="dbSNP:1347214138"
     variation       1307
                     /replace="t"
                     /db_xref="dbSNP:1057000154"
     variation       1309
                     /replace="d"
                     /db_xref="dbSNP:768453026"
     variation       1311
                     /replace="a"
                     /db_xref="dbSNP:747600729"
     variation       1311
                     /replace="g"
                     /db_xref="dbSNP:778947846"
     variation       1311
                     /replace="t"
                     /db_xref="dbSNP:1262000147"
     variation       1313
                     /replace="a"
                     /db_xref="dbSNP:909586512"
     variation       1313
                     /replace="i"
                     /db_xref="dbSNP:1320195327"
     variation       1313
                     /replace="t"
                     /db_xref="dbSNP:1216951703"
     variation       1315
                     /replace="p"
                     /db_xref="dbSNP:1331880698"
     variation       1316
                     /replace="a"
                     /db_xref="dbSNP:1275853216"
     variation       1316
                     /replace="r"
                     /db_xref="dbSNP:771724485"
     variation       1317
                     /replace="p"
                     /db_xref="dbSNP:1199413316"
     variation       1317
                     /replace="s"
                     /db_xref="dbSNP:1276426897"
     variation       1318
                     /replace="a"
                     /db_xref="dbSNP:199914909"
     variation       1320
                     /replace="a"
                     /db_xref="dbSNP:1218586522"
     variation       1321
                     /replace="l"
                     /db_xref="dbSNP:760439915"
     variation       1323
                     /replace="*"
                     /db_xref="dbSNP:1276551330"
     variation       1324
                     /replace="d"
                     /db_xref="dbSNP:1470113352"
     variation       1324
                     /replace="f"
                     /db_xref="dbSNP:1390250091"
     variation       1324
                     /replace="f"
                     /db_xref="dbSNP:1423822222"
     variation       1326
                     /replace="e"
                     /db_xref="dbSNP:866423509"
     variation       1326
                     /replace="t"
                     /db_xref="dbSNP:770205364"
     variation       1327
                     /replace="l"
                     /db_xref="dbSNP:944937579"
     variation       1330
                     /replace="a"
                     /db_xref="dbSNP:775791317"
     variation       1331
                     /replace="i"
                     /db_xref="dbSNP:1306188038"
     variation       1332
                     /replace="l"
                     /db_xref="dbSNP:1340624853"
     variation       1333
                     /replace="g"
                     /db_xref="dbSNP:763478913"
     variation       1334
                     /replace="a"
                     /db_xref="dbSNP:764111540"
     variation       1335
                     /replace="f"
                     /db_xref="dbSNP:1358317554"
     variation       1336
                     /replace="a"
                     /db_xref="dbSNP:137949763"
     variation       1336
                     /replace="i"
                     /db_xref="dbSNP:1003440716"
     variation       1338
                     /replace="l"
                     /db_xref="dbSNP:1248473597"
     variation       1338
                     /replace="l"
                     /db_xref="dbSNP:750648237"
     variation       1338
                     /replace="p"
                     /db_xref="dbSNP:921921872"
     variation       1339
                     /replace="-"
                     /db_xref="dbSNP:1460043397"
     variation       1339
                     /replace="y"
                     /db_xref="dbSNP:1367462842"
     variation       1340
                     /replace="q"
                     /db_xref="dbSNP:1276677729"
     variation       1342
                     /replace="l"
                     /db_xref="dbSNP:1482243638"
     variation       1343
                     /replace="k"
                     /db_xref="dbSNP:761920763"
     variation       1344
                     /replace="k"
                     /db_xref="dbSNP:750672575"
     variation       1344
                     /replace="s"
                     /db_xref="dbSNP:767626921"
     variation       1346
                     /replace="n"
                     /db_xref="dbSNP:1185481162"
     variation       1348
                     /replace="e"
                     /db_xref="dbSNP:754665050"
     variation       1348
                     /replace="m"
                     /db_xref="dbSNP:1036215311"
     variation       1350
                     /replace="g"
                     /db_xref="dbSNP:1204929114"
     variation       1351
                     /replace="l"
                     /db_xref="dbSNP:1170657477"
     variation       1352
                     /replace="r"
                     /db_xref="dbSNP:1391847194"
     variation       1354
                     /replace="v"
                     /db_xref="dbSNP:568752438"
     variation       1355
                     /replace="r"
                     /db_xref="dbSNP:1444452935"
     variation       1356
                     /replace="*"
                     /db_xref="dbSNP:747014614"
     variation       1357
                     /replace="i"
                     /db_xref="dbSNP:994602312"
     variation       1358
                     /replace="l"
                     /db_xref="dbSNP:1338295621"
     variation       1358
                     /replace="s"
                     /db_xref="dbSNP:1427575715"
     variation       1359
                     /replace="h"
                     /db_xref="dbSNP:1229894039"
     variation       1360
                     /replace="i"
                     /db_xref="dbSNP:1380012137"
     variation       1360
                     /replace="t"
                     /db_xref="dbSNP:1297580951"
     variation       1361
                     /replace="k"
                     /db_xref="dbSNP:1402800582"
     variation       1362
                     /replace="p"
                     /db_xref="dbSNP:752633898"
     variation       1362
                     /replace="r"
                     /db_xref="dbSNP:1195413336"
     variation       1362
                     /replace="s"
                     /db_xref="dbSNP:765112298"
     variation       1365
                     /replace="l"
                     /db_xref="dbSNP:758392435"
     variation       1366
                     /replace="r"
                     /db_xref="dbSNP:768919829"
     variation       1367
                     /replace="d"
                     /db_xref="dbSNP:946862042"
     variation       1367
                     /replace="v"
                     /db_xref="dbSNP:529439194"
     variation       1368
                     /replace="i"
                     /db_xref="dbSNP:1027776935"
     variation       1368
                     /replace="l"
                     /db_xref="dbSNP:777901092"
     variation       1368
                     /replace="t"
                     /db_xref="dbSNP:1448720687"
     variation       1369
                     /replace="a"
                     /db_xref="dbSNP:1428471307"
     variation       1369
                     /replace="q"
                     /db_xref="dbSNP:1164922176"
     variation       1370
                     /replace="*"
                     /db_xref="dbSNP:773319452"
     variation       1371
                     /replace="y"
                     /db_xref="dbSNP:760713322"
     variation       1374
                     /replace="v"
                     /db_xref="dbSNP:375535957"
     variation       1375
                     /replace="f"
                     /db_xref="dbSNP:771184154"
     variation       1375
                     /replace="y"
                     /db_xref="dbSNP:1293693363"
     variation       1378
                     /replace="r"
                     /db_xref="dbSNP:1131834"
     variation       1382
                     /replace="i"
                     /db_xref="dbSNP:1451612243"
     variation       1383
                     /replace="n"
                     /db_xref="dbSNP:1370264818"
     variation       1384
                     /replace="t"
                     /db_xref="dbSNP:777054582"
     variation       1385
                     /replace="k"
                     /db_xref="dbSNP:762780719"
     variation       1387
                     /replace="h"
                     /db_xref="dbSNP:763984144"
     variation       1389
                     /replace="s"
                     /db_xref="dbSNP:751499683"
     variation       1390
                     /replace="c"
                     /db_xref="dbSNP:761829442"
     variation       1391
                     /replace="l"
                     /db_xref="dbSNP:1316357445"
     variation       1391
                     /replace="s"
                     /db_xref="dbSNP:1267015282"
     variation       1393
                     /replace="r"
                     /db_xref="dbSNP:1222656665"
     variation       1393
                     /replace="t"
                     /db_xref="dbSNP:767399917"
     variation       1394
                     /replace="e"
                     /db_xref="dbSNP:1227001417"
     variation       1397
                     /replace="n"
                     /db_xref="dbSNP:1489361338"
     variation       1398
                     /replace="g"
                     /db_xref="dbSNP:529320349"
     variation       1400
                     /replace="a"
                     /db_xref="dbSNP:1044336778"
     variation       1401
                     /replace="v"
                     /db_xref="dbSNP:1219944923"
     variation       1402
                     /replace="s"
                     /db_xref="dbSNP:142437746"
     variation       1404
                     /replace="d"
                     /db_xref="dbSNP:779666926"
     variation       1406
                     /replace="a"
                     /db_xref="dbSNP:753500682"
     variation       1406
                     /replace="s"
                     /db_xref="dbSNP:1405181385"
     variation       1407
                     /replace="h"
                     /db_xref="dbSNP:892732121"
     variation       1409
                     /replace="a"
                     /db_xref="dbSNP:779272681"
     variation       1409
                     /replace="g"
                     /db_xref="dbSNP:755297530"
     variation       1412
                     /replace="v"
                     /db_xref="dbSNP:748512117"
     variation       1413
                     /replace="e"
                     /db_xref="dbSNP:1456017826"
     variation       1416
                     /replace="v*"
                     /db_xref="dbSNP:1302961337"
     CDS             1..1416
                     /gene="PTPRG"
                     /gene_synonym="HPTPG; PTPG; R-PTP-GAMMA; RPTPG"
                     /coded_by="XM_005265353.3:378..4628"
                     /db_xref="GeneID:5793"
                     /db_xref="HGNC:HGNC:9671"
                     /db_xref="MIM:176886"
ORIGIN      
        1 mrrllepcww ilflkitssv lhyvvcfpal tegyvgalhe nrhgsavqir rrkasgdpyw
       61 aysgaygpeh wvtssvscgg rhqspidild qyarvgeeyq elqldgfdne ssnktwmknt
      121 gktvaillkd dyfvsgaglp grfkaekvef hwghsngsag sehsingrrf pvemqiffyn
      181 pddfdsfqta isenriigam aiffqvsprd nsaldpiihg lkgvvhheke tfldpfvlrd
      241 llpaslgsyy rytgslttpp cseivewivf rrpvpisyhq leafysiftt eqqdhvksve
      301 ylrnnfrpqq rlhdrvvsks avrdswnhdm tdflenplgt easkvcsspp ihmkvqplnq
      361 talqvswsqp etiyhppimn ymisyswtkn edekektftk dsdkdlkati shvspdslyl
      421 frvqavcrnd mrsdfsqtml fqanttrifq gtrivktgvp taspassadm apissgsstw
      481 tssgipfsfv smatgmgpss sgsqatvasv vtstllaglg fggggissfp stvwptrlpt
      541 aasaskqaar pvlatteala spgpdgdssp tkdgegteeg ekdeksesed gereheedge
      601 kdsekkeksg vthaaeernq tepsptpssp nrtaegghqt ipgheqdhta vptdqtggrr
      661 dagpgldpdm vtstqvppta teeqyagsdp krpempskkp msrgdrfsed srfitvnpae
      721 kntsgmisrp apgrmewiip livvsaltfv clilliavlv ywrkcfqtah fyvedssspr
      781 vvpnesipii pipddmeaip vkqfvkhige lysnnqhgfs edfeevqrct admnitaehs
      841 nhpenkhknr yinilaydhs rvklrplpgk dskhsdyina nyvdgynkak ayiatqgplk
      901 stfedfwrmi weqntgiivm itnlvekgrr kcdqywpten seeygniivt lkstkihacy
      961 tvrrfsirnt kvkkgqkgnp kgrqnervvi qyhytqwpdm gvpeyalpvl tfvrrssaar
     1021 mpetgpvlvh csagvgrtgt yividsmlqq ikdkstvnvl gflkhirtqr nylvqteeqy
     1081 ifihdallea ilgketevss nqlhsyvnsi lipgvggktr lekqfklvtq cnakyvecfs
     1141 aqkecnkekn rnssvvpser arvglaplpg mkgtdyinas yimgyyrsne fiitqhplph
     1201 ttkdfwrmiw dhnaqiivml pdnqslaede fvywpsrees mnceaftvtl iskdrlclsn
     1261 eeqiiihdfi leatqddyvl evrhfqcpkw pnpdapisst felinvikee altrdgptiv
     1321 hdeygavsag mlcalttlsq qlenenavdv fqvakminlm rpgvftdieq yqfiykamls
     1381 lvstkengng pmtvdkngav liadesdpae smeslv
//
DBGET integrated database retrieval system