GenomeNet

Database: RefSeq
Entry: XP_006497853
LinkDB: XP_006497853
Original site: XP_006497853 
LOCUS       XP_006497853             602 aa            linear   ROD 22-JUN-2016
DEFINITION  PREDICTED: prostaglandin G/H synthase 1 isoform X1 [Mus musculus].
ACCESSION   XP_006497853
VERSION     XP_006497853.1
DBLINK      BioProject: PRJNA169
DBSOURCE    REFSEQ: accession XM_006497790.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000068.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Mus musculus Annotation Release 106
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.1
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Mus musculus"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="2"
     Protein         1..602
                     /product="prostaglandin G/H synthase 1 isoform X1"
                     /calculated_mol_wt=68912
     Region          35..72
                     /region_name="EGF_CA"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; cd00054"
                     /db_xref="CDD:238011"
     Region          92..578
                     /region_name="prostaglandin_endoperoxide_synthase"
                     /note="Animal prostaglandin endoperoxide synthase and
                     related bacterial proteins; cd09816"
                     /db_xref="CDD:188648"
     Site            order(119,207,347,350..351,355,357,383,387,389,520,524,
                     528..529,532..533,536)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:188648"
     Site            order(127,129..131,138..142,144,231,321..325,328..329,332,
                     335..336,339,369..376,539..540,543..547,549..551,553..554)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:188648"
     Site            order(150,201,205,209,212..214,297,384,387..390,393,410,
                     446,448..449,452)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:188648"
     CDS             1..602
                     /gene="Ptgs1"
                     /gene_synonym="Cox-1; Cox-3; COX1; PGHS-1; Pghs1; PHS 1"
                     /coded_by="XM_006497790.3:1325..3133"
                     /db_xref="GeneID:19224"
                     /db_xref="MGI:MGI:97797"
ORIGIN      
        1 msrrslslwf plllllllpp tpsvlladpg vpspvnpccy ypcqnqgvcv rfgldnyqcd
       61 ctrtgysgpn ctipeiwtwl rnslrpspsf thfllthgyw lwefvnatfi revlmrlvlt
      121 vrsnlipspp tynsahdyis wesfsnvsyy trilpsvpkd cptpmgtkgk kqlpdvqlla
      181 qqlllrrefi papqgtnilf affaqhfthq ffktsgkmgp gftkalghgv dlghiygdnl
      241 erqyhlrlfk dgklkyqvld gevyppsveq asvlmryppg vpperqmavg qevfgllpgl
      301 mlfstiwlre hnrvcdllke ehptwddeql fqttrlilig etikivieey vqhlsgyflq
      361 lkfdpellfr aqfqyrnria mefnhlyhwh plmpnsfqvg sqeysyeqfl fntsmlvdyg
      421 vealvdafsr qragrigggr nfdyhvlhva vdvikesrem rlqpfneyrk rfglkpytsf
      481 qeltgekema aeleelygdi dalefypgll lekcqpnsif gesmiemgap fslkgllgnp
      541 icspeywkps tfggdvgfnl vntaslkklv clntktcpyv sfrvpdypgd dgsvlvrrst
      601 el
//
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