LOCUS       XP_016856778             775 aa            linear   PRI 05-OCT-2023
DEFINITION  aryl hydrocarbon receptor nuclear translocator isoform X2 [Homo
            sapiens].
ACCESSION   XP_016856778
VERSION     XP_016856778.1
DBLINK      BioProject: PRJNA168
DBSOURCE    REFSEQ: accession XM_017001289.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/02/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     Protein         1..775
                     /product="aryl hydrocarbon receptor nuclear translocator
                     isoform X2"
                     /calculated_mol_wt=85165
     Region          77..141
                     /region_name="bHLH-PAS_ARNT"
                     /note="basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS)
                     domain found in aryl hydrocarbon receptor nuclear
                     translocator (ARNT) and similar proteins; cd18947"
                     /db_xref="CDD:381517"
     Site            order(81..82,85..86,89,92..93,97,118..119)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381517"
     Site            order(96,99,102..103,120,123..124,127,129..131,133)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:381517"
     Region          154..260
                     /region_name="PAS"
                     /note="PAS fold; pfam00989"
                     /db_xref="CDD:395786"
     Region          348..448
                     /region_name="PAS_11"
                     /note="PAS domain; pfam14598"
                     /db_xref="CDD:434060"
     CDS             1..775
                     /gene="ARNT"
                     /gene_synonym="ARNT1; bHLHe2; HIF-1-beta; HIF-1beta;
                     HIF1-beta; HIF1B; HIF1BETA; TANGO"
                     /coded_by="XM_017001289.2:95..2422"
                     /db_xref="GeneID:405"
                     /db_xref="HGNC:HGNC:700"
                     /db_xref="MIM:126110"
ORIGIN      
        1 mtsdvpslgp aiasgnsgpg iqgggaivqr aikrrpgldf dddgegnskf lrcdddqmsn
       61 dkerfarsdd eqssadkerl arenhseier rrrnkmtayi telsdmvptc salarkpdkl
      121 tilrmavshm kslrgtgnts tdgsykpsfl tdqelkhlil eaadgflfiv scetgrvvyv
      181 sdsvtpvlnq pqsewfgstl ydqvhpddvd klreqlstse naltgrildl ktgtvkkegq
      241 qssmrmcmgs rrsficrmrc gsssvdpvsv nrlsfvrnrc rnglgsvkdg ephfvvvhct
      301 gyikawppad ddpeagqgsk fclvaigrlq vtsspnctdm snvcqptefi srhniegift
      361 fvdhrcvatv gyqpqellgk nivefchped qqllrdsfqq vvklkgqvls vmfrfrsknq
      421 ewlwmrtssf tfqnpysdei eyiictntnv knssqeprpt lsntiqrpql gptanlplem
      481 gsgqlaprqq qqqteldmvp grdglasynh sqvvqpvttt gpehskplek sdglfaqdrd
      541 prfseiyhni nadqskgiss stvpatqqlf sqgntfpptp rpaenfrnsg lappvtivqp
      601 sasagqmlaq isrhsnptqg atptwtpttr sgfsaqqvat qataktrtsq fgvgsfqtps
      661 sfssmslpga ptaspgaaay psltnrgsnf apetgqtagq fqtrtaegvg vwpqwqgqqp
      721 hhrsssseqh vqqppaqqpg qpevfqemls mlgdqsnsyn neefpdltmf ppfse
//