GenomeNet

Database: RefSeq
Entry: XP_017346360
LinkDB: XP_017346360
Original site: XP_017346360 
LOCUS       XP_017346360            1538 aa            linear   VRT 09-MAR-2023
DEFINITION  rho GTPase-activating protein 35 [Ictalurus punctatus].
ACCESSION   XP_017346360
VERSION     XP_017346360.1
DBLINK      BioProject: PRJNA327588
DBSOURCE    REFSEQ: accession XM_017490871.3
KEYWORDS    RefSeq.
SOURCE      Ictalurus punctatus (channel catfish)
  ORGANISM  Ictalurus punctatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
            Ictaluridae; Ictalurus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_030432) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_001660625.3-RS_2023_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/03/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1538
                     /organism="Ictalurus punctatus"
                     /db_xref="taxon:7998"
                     /chromosome="17"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
                     /breed="USDA103"
                     /note="double haploid"
     Protein         1..1538
                     /product="rho GTPase-activating protein 35"
                     /calculated_mol_wt=173373
     Site            28..35
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206648"
     Site            order(30..36,98,199..200,202,228..230)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:206648"
     Site            66
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206648"
     Site            order(70,72..73)
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:206648"
     Site            order(94,96..98)
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:206648"
     Site            order(97..98,157..158)
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:206648"
     Region          <157..246
                     /region_name="P-loop_NTPase"
                     /note="P-loop containing Nucleoside Triphosphate
                     Hydrolases; cl38936"
                     /db_xref="CDD:453896"
     Site            199..202
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206648"
     Site            228..230
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206648"
     Region          260..339
                     /region_name="RhoGAP-FF1"
                     /note="p190-A and -B Rho GAPs FF domain; pfam16512"
                     /db_xref="CDD:435388"
     Region          430..482
                     /region_name="FF"
                     /note="Contains two conserved F residues; smart00441"
                     /db_xref="CDD:128718"
     Region          557..1267
                     /region_name="RhoGAP_pG1_pG2"
                     /note="p190RhoGAP, pG1 and pG2 domains; pfam19518"
                     /db_xref="CDD:437350"
     Region          1263..1447
                     /region_name="RhoGAP_p190"
                     /note="RhoGAP (GTPase-activator protein [GAP] for Rho-like
                     small GTPases) domain of p190-like proteins. p190, also
                     named RhoGAP5, plays a role in neuritogenesis and axon
                     branch stability. p190 shows a preference for Rho, over
                     Rac and Cdc42, and consists of an...; cd04373"
                     /db_xref="CDD:239838"
     Site            order(1300,1338,1342,1411,1414..1415,1438)
                     /site_type="other"
                     /note="putative GTPase interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:239838"
     Site            1300
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:239838"
     CDS             1..1538
                     /gene="arhgap35a"
                     /coded_by="XM_017490871.3:1072..5688"
                     /db_xref="GeneID:108277872"
ORIGIN      
        1 mmakkhdara ptynlvvvgl sgtekekgqc gvgksclcnr fvrpsaddfy ldhtsvlsts
       61 dfggrvvnnd hflfwgeasr pleegpecrm hvveqtefid dqtfqphrst alqpyikraa
      121 stklasaekl myfctdqlgl eqdfeqkqmp egkllvdgfl lcvdvsrgmn rnfddqmkfi
      181 snlynqlakt kkpvvlvltk cdegveryik dshtfalakk nlqvvetsar snvnvdlafl
      241 tlvqlidksr gkpkiipyfe alkqqsqqia sakdryewlv scivknhnet wpninrrmqt
      301 speykdyvfl egtskakklf qqhvhrlkqd hiekrrriyl stlpqalctl vpdldeidhl
      361 swsgvqkvle tkrgfsqwfv ilddtpwett phidnmeder ipqdlletpa aeviyeshle
      421 hlrnerkrae mrrefkeklv aspfvtpgkp weearsfimn eefyqwleep eyldmynkhq
      481 keiidqaked fqellleyse lfyelevdak pskekmgaiq evlgeeqrfk alqklqaerd
      541 alvlkhihfv yhptketcpn spycvdskie qilatrfptr yafdgtlksq ygegkvdrin
      601 lvilgkdgla relaneiram ctsddrytld gktyelalrp iegnvrlpvn sfhtptftph
      661 gclclynske slsyvvesie klrestigrr dnslallpms lllvtkrgvg sigdiggeta
      721 qsliiqgqqv agklqcayld paspgagyar nlnekqinqv lkslldvqrp lgslgssspp
      781 lpaprarfrd shaqqtsead lhvvmcimcg dtydvdqlls pflhsqhcrp sanlssgtsv
      841 lldltigsqr qtidlavlsy hstfslrksr lvhgyiavys akrkasletl caflcevqdi
      901 ipvqllavge tqaeltesev ardqlvegee laheiegrfs svvcgpggvv gglhridlfq
      961 pflkevvekr tiveathmyd nvaeacstne svhsprcgsp svpmldsedd vepsppcpiy
     1021 rddstlthgf kfsdlessdt fsviseistf esklnnkvpp qvrpkptvtf gkvslgsymd
     1081 hggnrrslps vtwppssdgg ydpsdysepv davpkprpte eeniysvphd stqgkiitir
     1141 nankshsngg gngsdseadn sslerrrnls tvgikprlyr drskrlgkfs nfrtsfigsd
     1201 delggppktk edemgiqkgd nslneecedp krnkilrslr rtgkktrpkp rqsiskqles
     1261 nyfgvplvnv vtaerpiplf iekciryiea tglstegiyr vsgnkaemes iqrqfdqdsn
     1321 ldlvekdfsv ntvagamksf fselpdplvp ynmqvelvea fkindreqrf ltmkdvlrrf
     1381 prenydvfky vishlnkvsq nsrvnlmtsd nlsicfwptl mrpdfttmda ltatrtyqti
     1441 ietfiyqcaf ffynqplvdt tsglpglpgs ptatlsstts msgsaysscy tpvqhvatpf
     1501 sqsqqspphs ppptpqspiq sllppmhphh tsteqhtl
//
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