LOCUS       XP_848685               1873 aa            linear   MAM 06-JAN-2021
DEFINITION  voltage-dependent L-type calcium channel subunit alpha-1S isoform
            X1 [Canis lupus familiaris].
ACCESSION   XP_848685
VERSION     XP_848685.4
DBLINK      BioProject: PRJNA12384
DBSOURCE    REFSEQ: accession XM_843592.7
KEYWORDS    RefSeq.
SOURCE      Canis lupus familiaris (dog)
  ORGANISM  Canis lupus familiaris
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
            Canis.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_006589.4) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 6, 2021 this sequence version replaced XP_848685.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Canis lupus familiaris Annotation
                                           Release 106
            Annotation Version          :: 106
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1873
                     /organism="Canis lupus familiaris"
                     /isolate="Tasha"
                     /sub_species="familiaris"
                     /db_xref="taxon:9615"
                     /chromosome="7"
                     /sex="female"
                     /breed="boxer"
     Protein         1..1873
                     /product="voltage-dependent L-type calcium channel subunit
                     alpha-1S isoform X1"
                     /calculated_mol_wt=212233
     Region          50..345
                     /region_name="Ion_trans"
                     /note="Ion transport protein; pfam00520"
                     /db_xref="CDD:425730"
     Region          431..672
                     /region_name="Ion_trans"
                     /note="Ion transport protein; pfam00520"
                     /db_xref="CDD:425730"
     Region          798..1075
                     /region_name="Ion_trans"
                     /note="Ion transport protein; pfam00520"
                     /db_xref="CDD:425730"
     Region          1117..1392
                     /region_name="Ion_trans"
                     /note="Ion transport protein; pfam00520"
                     /db_xref="CDD:425730"
     Region          1401..1454
                     /region_name="GPHH"
                     /note="Voltage-dependent L-type calcium channel,
                     IQ-associated; pfam16905"
                     /db_xref="CDD:435642"
     Region          1464..1536
                     /region_name="Ca_chan_IQ"
                     /note="Voltage gated calcium channel IQ domain; pfam08763"
                     /db_xref="CDD:430200"
     Region          1557..1833
                     /region_name="CAC1F_C"
                     /note="Voltage-gated calcium channel subunit alpha,
                     C-term; pfam16885"
                     /db_xref="CDD:435629"
     CDS             1..1873
                     /gene="CACNA1S"
                     /coded_by="XM_843592.7:94..5715"
                     /db_xref="GeneID:490244"
                     /db_xref="VGNC:VGNC:38640"
ORIGIN      
        1 mepsspqdeg lrkkqpkkpv peilprppra lfcltlqnpl rkacinivew kpfetiillt
       61 ifancvalav ylpmpeddnn tlnlglekle yfflivfsie aamkiiaygf lfhqdaylrs
      121 gwnvldfiiv flgvftvile qvnviqsnta pmsskgagld vkalrafrvl rplrlvsgvp
      181 slqvvlnsif kamlplfhia llvlfmviiy aiiglelfkg kmhktcyfig tdivatvene
      241 kpspcartgs grpctingse crggwpgpnh githfdnfgf smltvyqcit megwtdvlyw
      301 vndaignewp wiyfvtlill gsffilnlvl gvlsgeftke rekaksrgtf qklrekqqle
      361 edlrgymswi tqgevmdved lregklslde ggsdteslye ieglnkiiqf vrhwrqwnri
      421 frwkchdvik srvfywlvil vvalntlsia sehhnqplwl thlqdvanrv llalftveml
      481 mkmyglglrq yfmsifnrfd cfvvcsglle illvesgams plgisvlrci rllrifkitk
      541 ywtslsnlva sllnsirsia slllllflfi iifallgmql fggrydfedt evrrsnfdnf
      601 pqalisvfqv ltgedwnsmm ysgimayggp sypgvlvciy fiilfvcgny illnvflaia
      661 vdnlaeaesl tsaqkakaee rkrrkmskgl pdkseeeksv makkleqkpk gegipttakl
      721 kidefesnvn evkdpypsad fpgddeedep eipvsprprp laelqlkeka vpipeassff
      781 ifsptnkirv lchrivnatw ftnfillfil lssaalaaed piraesvrnq ilgyfdiaft
      841 svftveivlk mttygaflhk gsfcrnyfni ldllvvavsl ismglessti svvkilrvlr
      901 vlrplrainr akglkhvvqc vfvairtign ivlvttllqf mfacigvqlf kgkffscndl
      961 skmteqecrg yyyvykdgdp tqmelrprqw ihsdfhfdnv lsammslftv stfegwpqll
     1021 yqaidsyked mgpvynnrve maiffiiyii liaffmmnif vgfvivtfqe qgeteyknce
     1081 ldknqrqcvq yalkarplrc yipknpyqyq vwyvvtssyf eylmfaliml nticlgmqhy
     1141 nqseemnhis dilnvaftii ftlemvlklm afkargyfgd pwnvfdfliv igsiidvils
     1201 eidtflassg glyclgggcg nvdpdesari ssaffrlfrv mrlikllsra egvrtllwtf
     1261 iksfqalpyv allivmlffi yavigmqmfg kiamvdgtqi nrnnnfqtfp qavlllfrca
     1321 tgeawqeill acsygklcdp esdyapgeey tcgtnfayyy fisfymlcaf liinlfvavi
     1381 mdnfdyltrd wsilgphhld efkaiwaeyd peakgrikhl dvvtllrriq pplgfgkfcp
     1441 hrvackrlvg mnmplnsdgt vtfnatlfal vrtalkikte gnfeqaneel raiikkiwkr
     1501 tsmklldqvi ppigddevtv gkfyatfliq ehfrkfmkrq eeyygyrpkk dtiqiqaglr
     1561 tieeeaapei rrtisgdlta eeeleramve aameegifrr tgglfgqvdn flertnslpp
     1621 vmanqrplqf aeiemeeles pvfledfpqd prtnplaran tnnananvah dnsdhsnsqv
     1681 fssiryeref pgepeppaar ggalgqprrv lgphgrpcve klkgqrtqre mprpqaspap
     1741 cqcagperpl peerscpppg slpqgappsr rptesgcrcp tpatarlvre alvrggldtl
     1801 aadasfvmat gqaladacrm epedvevaat ellkkqespe grasalgrrs rgsslgsldl
     1861 hlgsretlvp prq
//