LOCUS       XP_852399               2701 aa            linear   MAM 06-JAN-2021
DEFINITION  inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [Canis
            lupus familiaris].
ACCESSION   XP_852399
VERSION     XP_852399.2
DBLINK      BioProject: PRJNA12384
DBSOURCE    REFSEQ: accession XM_847306.6
KEYWORDS    RefSeq.
SOURCE      Canis lupus familiaris (dog)
  ORGANISM  Canis lupus familiaris
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
            Canis.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_006609.4) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 6, 2021 this sequence version replaced XP_852399.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Canis lupus familiaris Annotation
                                           Release 106
            Annotation Version          :: 106
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2701
                     /organism="Canis lupus familiaris"
                     /isolate="Tasha"
                     /sub_species="familiaris"
                     /db_xref="taxon:9615"
                     /chromosome="27"
                     /sex="female"
                     /breed="boxer"
     Protein         1..2701
                     /product="inositol 1,4,5-trisphosphate receptor type 2
                     isoform X1"
                     /calculated_mol_wt=307958
     Region          4..228
                     /region_name="Ins145_P3_rec"
                     /note="Inositol 1,4,5-trisphosphate/ryanodine receptor;
                     pfam08709"
                     /db_xref="CDD:430167"
     Region          232..432
                     /region_name="MIR"
                     /note="MIR domain; pfam02815"
                     /db_xref="CDD:397103"
     Region          475..670
                     /region_name="RYDR_ITPR"
                     /note="RIH domain; pfam01365"
                     /db_xref="CDD:426222"
     Region          1202..1344
                     /region_name="RYDR_ITPR"
                     /note="RIH domain; pfam01365"
                     /db_xref="CDD:426222"
     Region          1915..2022
                     /region_name="RIH_assoc"
                     /note="RyR and IP3R Homology associated; pfam08454"
                     /db_xref="CDD:430005"
     Region          2290..2552
                     /region_name="Ion_trans"
                     /note="Ion transport protein; pfam00520"
                     /db_xref="CDD:425730"
     CDS             1..2701
                     /gene="ITPR2"
                     /coded_by="XM_847306.6:96..8201"
                     /db_xref="GeneID:486628"
                     /db_xref="VGNC:VGNC:42158"
ORIGIN      
        1 msdkmssfly igdivslyae gsvngfistl glvddrcvvh peagdlanpp kkfrdclfkv
       61 cpmnrysaqk qywkakqakq gnhteaallk klqhaaeleq kqnesenkkl lgeivkysnv
      121 iqllhiksnk yltvnkrlpa lleknamrvs ldaagnegsw fyihpfwklr segdnivvgd
      181 kvvlmpvnag qplhasniel ldnpgckevn avncntswki tlfmkyssyr edvlkggdvv
      241 rlfhaeqekf ltcdeyekkq hiflrttlrq satsatsska lweievvhhd pcrggagqwn
      301 slfrfkhlat gnylaaelnp dyrdaqnegk nlrdgdlpts kkkrqageki mytlvsvphg
      361 ndiaslfeld attlqradcl vprnsyvrlr hlctntwvts tsipidtdee rpvmlkigtc
      421 qtkedkeafa ivsvplsevr dldfandank vlattvkkle ngtitqnerr fvtklledli
      481 ffvadvlnng qevldvvitk pnrerqklmr eqnilaqvfg ilkapfkeka gegsmlrled
      541 lgdqryapyk ymlrlcyrvl rhsqqdyrkn qeyiaknfcv mqsqigydil aedtitallh
      601 nnrkllekhi takeietfvs llrrnreprf ldylsdlcvs nttaipvtqe lickfmlspg
      661 nadiliqtkl vsmqvdnpme ssilsddidd eevwlywids nkephgkair hlaqeakegt
      721 kadlevltyy ryqlnlfarm cldrqylain qistqlsvdl ilrcvsdesl pfdlrasfcr
      781 lmlhmhvdrd pqesvvpvry arlwteiptk itiheydsit dssrndmkrk faltmefvee
      841 ylkevvnqpf pfgdkeknkl tfevvhlarn liyfgfysfs ellrltrtll aildivqapm
      901 ssyferlskf qdggnnvmrt ihgvgemmtq mvlsrgsifp msvpdiqpsi hpskqgspve
      961 hedvtvmdtk lkiieilqfi lsvrldyris ymlsiykkef gennentets angspdtllp
     1021 saivpdidei aaqaetmfag rkeknpvqld deggrtflrv lihlimhdyp pllsgalqll
     1081 fkhfsqraev lqafkqvqll vsnqdvdnyk qikadldqlr ltvekselwv eksssyenge
     1141 mgesqvkgge epieessils pvqdgtrkpq idsnksnnyr ivkeilirls klcvqnkkcr
     1201 nqhqrllknm gahsvvldll kipyekndek mnevmnlaht flqnfcrgnp qnqvllhkhl
     1261 nlfltpglle aetmrhifmn nyhlcneise rvvqhfvhci ethgrhveyl rflqtivkad
     1321 gkyvkkcqdm vmtelingge dvlifyndra sfpillhmmc serdrgdesg playhitlve
     1381 llaactegkn vyteikcnsl lplddivrvv thddcipevk iayvnfvnhc yvdtevemke
     1441 iytsnhiwkl fenflvdmar vcntttdrkh adtflekcvt esimnivsgf fnspfsdnst
     1501 slqthqpvfi qllqsafriy nctwpnpaqk ssvescirtl aevaknrgia ipvdldsqvn
     1561 tlflkshsnm vqraamgwrl sarsgprfke alggpawdyr niieklqdvv asleqqfspm
     1621 mqaefsvlvd vlyspellfp egsdarircg afmsklinht kklmekeekl cikilqtlre
     1681 mlekkdsfve egntlrkill nryfkgdygv gmnghlsgty cksaqgggsf sgqdsdkmgi
     1741 smsdiqclld kegaselvid vivntkndri fsegillgia lleggntqtq ysfyqqlheq
     1801 kksekffkvl ydrmkaaqke irstvtvnti dlgnkkrddd nelmtagprm rvrdsslllk
     1861 egmkgqltea ssatskayca yrremdpeid imcagseagh aeeksaeevt mspaiaimqp
     1921 ilrflqllce nhnrelqnfl rnqnnktnyn lvcetlqfld cicgsttggl gllglyinek
     1981 nvvlvnqtle slteycqgpc henqtciath esngidiiia lilndinplg kyrmdlvlql
     2041 knnaskllla imesrhdsen aerilfnmrp relvdvmkna ynqglecdhg ddeggddgvs
     2101 pkdvghniyi lahqlarhnk llqqmlkpgs dpddgdealk yyanhtaqie ivrhdrtmeq
     2161 ivfpvpnice yltreskfrv fntterdeqg skvndffqqt edlynemkwq kkirnnpalf
     2221 wfsrhislwg sisfnlavfi nlavalfypf gddgdegtls plfsvllwia vaictsmlff
     2281 fskpvgirpf lvsimlrsiy tiglgptlil lgaanlcnki vflvsfvgnr gtftrgyrav
     2341 ildmaflyhv ayvlvcmlgl fvheffysfl lfdlvyreet llnviksvtr ngrsiiltav
     2401 lalilvylfs iigflflkdd ftmevdrlkn rtpitgsnev ptmtltsmmg tckndncspt
     2461 ipasntadee yedgiertcd tllmcivtvl nqglrngggv gdvlrrpskd eplfaarvvy
     2521 dllfyfivii ivlnlifgvi idtfadlrse kqkkeeilkt tcficglerd kfdnktvsfe
     2581 ehiksehnmw hylyflvlvk vkdpteytgp esyvaqmive knldwfprmr amslvsnegd
     2641 seqneirnlq eklestmslv kqlsaqlael keqmteqrkn kqrlgflgsn tphvnhhmpp
     2701 h
//