KEGG   Roseburia hominis: RHOM_02230
Entry
RHOM_02230        CDS       T01621                                 
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
rho  Roseburia hominis
Pathway
rho00300  Lysine biosynthesis
rho00550  Peptidoglycan biosynthesis
rho01100  Metabolic pathways
rho01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:rho00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    RHOM_02230
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    RHOM_02230
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    RHOM_02230
Enzymes [BR:rho01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     RHOM_02230
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AEN95568
UniProt: G2T1S4
Position
483480..484910
AA seq 476 aa
MGAIMKNMTLEHIAQACGGTYIGEECDRKKEIQGAVIDSRLVGEGYLFIPIRGARVDGHD
FIPAVFEKGALAVLSEQRLEHPAGPYILVDSTEEAMKKIAAFYRRSLDIKVVGITGSVGK
TSTKEMIASVLSEKYRVLKTEGNLNNEIGLPLTIFKIREEHQVAVLEMGISEFGEMHRLA
EMAQPDICVITNIGLCHLENLITRDGILKAKTESFEHLAPDGIAVLNGDDDKLCDKKMVN
GRPAVFYGIGQEAKTAETETGSKRLAEKEVYATDVEAIGLEGTKAVIHTPEQQFEVVIPI
AGEHNVYNALAAVCVARRLGLDAEEMKLGIEHAHTIGGRSNLIRKNGITIIDDCYNANPV
SMMASIDVLSQAKGRKIAVLGDMGELGSEEKKLHGMVGTHFAGKKIDALFVTGTLAGEIA
EEARRVAPETRVYAEPDKEALEEALLEYRRPGDTILVKASHFMGFSEIVKKLEQPQ
NT seq 1431 nt   +upstreamnt  +downstreamnt
atgggagccattatgaaaaatatgacattggagcatatcgcgcaggcgtgcggcggtaca
tacatcggggaagaatgcgaccgcaaaaaggagattcagggggcggtgattgacagccgt
ctggtcggggagggatatctgtttattcccatccgcggagcgcgcgtcgacggacatgat
ttcattccggcggtttttgaaaagggagcgcttgccgtgctctccgagcagcggctcgag
catccggcaggaccgtatattctggttgactctacggaggaagccatgaagaagatcgcg
gcgttctaccgccgctcactcgacatcaaagtcgtggggatcacaggaagcgttggaaag
accagcacaaaagagatgattgcgtcggtgctctccgagaaataccgcgtgttaaagacc
gaggggaatctgaacaatgagattggacttccgctgacgatctttaagatccgggaggaa
catcaggtggcggtgctcgagatgggaatctctgagttcggtgagatgcaccgtcttgca
gagatggcacagccggatatctgcgtcattaccaatatcggcttatgtcatttggagaac
ctcatcacaagagacggcattttaaaggcgaagacggagagctttgagcatctggcaccg
gacgggatcgccgtattaaacggggatgacgataagctctgtgacaaaaagatggtgaat
ggcagaccggcggtgttctatggaatcggacaggaagcaaagacggcagagacagagacc
ggcagcaaacggctcgcggaaaaggaagtgtacgcgaccgatgtggaggcgatcggcctt
gagggaacgaaggcggtcattcacacgccggagcagcagtttgaggtggtgatcccgatt
gctggtgagcacaatgtatacaacgcgcttgcagcagtctgcgtggcaagacggctggga
cttgatgcggaggagatgaagcttggaattgagcatgcgcacacgattggcgggcggagt
aatctgatccggaaaaacggcatcacaattatcgacgactgctacaatgcgaatccggtg
tccatgatggcttccatagacgtgctgtcccaggcgaagggacgaaagattgccgtgctc
ggcgatatgggagaactcggcagtgaggaaaagaagctgcacggaatggtcggcacacac
tttgcggggaagaagatcgatgcgctgtttgtgaccggaacacttgcaggggagattgcg
gaggaggcgcggcgtgtagcgccggagaccagggtctatgcggaaccggacaaagaggcg
ctggaggaggcgctgctggagtaccgcagaccgggggataccattctggtaaaggcgtcc
cattttatgggattttcggagattgtgaaaaaattggaacagccacagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (50)   
   KEGG ORTHOLOGY (1)   
   RefGene (47)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (72)   

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