KEGG   Cupriavidus metallidurans: Rmet_0088
Entry
Rmet_0088         CDS       T00351                                 
Symbol
metH
Name
(GenBank) methionine synthase, cobalamine dependent
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
rme  Cupriavidus metallidurans
Pathway
rme00270  Cysteine and methionine metabolism
rme00450  Selenocompound metabolism
rme00670  One carbon pool by folate
rme01100  Metabolic pathways
rme01110  Biosynthesis of secondary metabolites
rme01230  Biosynthesis of amino acids
rme04980  Cobalamin transport and metabolism
Brite
KEGG Orthology (KO) [BR:rme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Rmet_0088 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Rmet_0088 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Rmet_0088 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    Rmet_0088 (metH)
Enzymes [BR:rme01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Rmet_0088 (metH)
SSDB
Motif
Pfam: Met_synt_B12 Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ABF06974
UniProt: Q1LSA2
Position
94333..97080
AA seq 915 aa
MSQQNLPPRPMRLSGLEPFTIDDDTLFVNVGERTNVTGSKAFARMILNGQFDEALAVARQ
QVENGAQIIDINMDEAMLDSKAAMVRFLNLIASEPDIARVPIMIDSSKWDVIEAGLRCVQ
GKAVVNSISLKEGEEQFRHHATQIRRYGAASVVMAFDEKGQADTFERKTEICKRSYDFLV
NEVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEATRWIKQNLPYAKVSGGVSNVSFSF
RGNDVVREAIHTVFLYHAIAAGMDMGIVNAGQLGVYDQLDPELRERVEDVVLNRRDDATD
RLLEIADRFKGGGTKREENLAWRGTPEQPVPVGDRLAHALVHGITTFIVEDTEEVRQQIA
ARGGRPIEVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPFIEEEKRLV
AEAGGDVRARGKIVIATVKGDVHDIGKNIVSVVLQCNNFEVVNMGVMVPCNEILARAKVE
GADIVGLSGLITPSLEEMAYVASEMQRDDYFRVKKIPLLIGGATTSRVHTAVKIAPNYEG
PVVYVPDASRSVSVASNLLSDEGAAKYLDELKSDYDRIRTQHANKKATPMVSLAQARANK
TPIDWSAYVPPKPKFIGRRVFRNYDLSELANYIDWGPFFQTWDLAGKFPDILNDEIVGES
ARRVFSDGKSMLARLIQGRWLTANGVMALLPANTVNDDDVEIYTDESRSKVALTWNNLRQ
QSERPVVDGVRRPNRCLADFIAPKSSGVADYIGLFAVTAGIGVDKKEAQFEADHDDYSAI
MLKALADRLAEAFAECLHERVRKDLWGYDAAESLNNDQLVAEAYRGIRPAPGYPACPEHT
VKAPMFAFLDAADIGMGITEGLAMTPAASVSGFYLSHPDSTYFSIGKIGQDQLDDMVARR
GEDRLTLERALAPNL
NT seq 2748 nt   +upstreamnt  +downstreamnt
atgagccagcaaaacctgcccccgcgtccgatgcgcctgtccggtctggagccgtttacg
atcgacgacgacacgctgttcgtcaacgttggcgagcgtaccaacgtcaccggttcgaag
gcattcgcgcgcatgatcctgaacggccagttcgacgaagccctggcggtggcccgccag
caggtggagaacggcgcgcagatcatcgacatcaacatggacgaggcgatgctcgattcg
aaggcggcgatggtgcgcttcctgaatctgatcgcatctgagccggacatcgcgcgcgtg
ccgatcatgatcgattcgtcgaagtgggacgtgatcgaggcgggcctgcgctgtgtgcag
ggcaaggccgtggtgaactcgatctcgctcaaggaaggtgaggaacagtttcgccaccac
gccacgcagatccgccgttatggcgcggccagcgtggtgatggcattcgacgagaagggc
caggcggacacgttcgagcgcaagaccgagatctgcaagcgcagctacgacttcctcgtg
aacgaagtgggcttcccgcccgaggacatcatcttcgatccgaacatcttcgcggtggcc
accggtatcgaggagcacaacaactacgcggtggacttcatcgaagccacgcgctggatc
aagcagaacctgccgtacgccaaggtcagcggcggggtgtcgaacgtgtcgttctcgttc
cgcggcaacgacgtggtgcgcgaggcgatccacaccgtgttcctgtaccacgcgatcgcg
gcgggcatggacatgggcatcgtcaacgccggccagcttggcgtgtacgaccagctcgac
ccggaattgcgcgagcgcgtggaagacgtggtgctgaaccgtcgcgacgacgccaccgat
cgcctgctggagatcgccgaccgcttcaagggcggtggcacgaagcgggaagagaacctg
gcctggcgcggcacgcccgagcaaccggtgccggtgggcgatcgcctggcgcacgcgctg
gtgcacggcatcaccacgttcatcgtcgaggacaccgaggaagtgcgccagcagatcgcg
gcgcgcggtggccgtcccatcgaggtgatcgaggggccgctgatggatggcatgaacatc
gtcggcgacctgttcggcgcgggcaagatgttcctgccgcaagtggtgaagagcgcccgt
gtgatgaagcaggccgtggcgcatctgctgccgtttatcgaggaagaaaagcgcctggtg
gccgaggccggcggcgacgtgcgcgcgcgcggcaagatcgtgatcgccaccgtgaagggc
gacgtgcacgacatcggcaagaacatcgtgtcggtggtgctccagtgcaacaacttcgaa
gtggtcaacatgggcgtgatggtgccgtgcaacgagatcctggcgcgcgctaaggtcgag
ggcgcggacattgtcgggctgtccggcctgatcacgccgtcgctcgaggaaatggcctac
gttgcctcggagatgcagcgcgacgattacttccgcgtgaagaagattccgctgctgatc
ggcggcgccaccacatcgcgcgtgcataccgcggtcaagatcgcgccgaactatgaaggc
ccggtggtctacgtgcccgatgcctcgcgctctgtcagcgtggcgtcgaacctcttgtct
gacgaaggcgcggcgaagtatctggacgagctgaagtccgactacgaccgcattcgcacg
cagcacgccaacaagaaggccacgccgatggtgtcgctggcccaggcgcgcgccaacaag
acgccgatcgactggagcgcctatgtgccgccgaagccgaagttcatcggccgccgcgtg
ttccgcaactacgatctgtccgaactggccaactacatcgactggggcccgttcttccag
acctgggacctggccggcaaattcccggacatcctaaacgacgagatcgtcggcgaatcg
gcccgacgcgtcttctcggatggcaagagcatgctggctcgcctgatccagggacgctgg
ctgacggccaacggcgtgatggcgctgctgccggccaatacggtcaatgacgacgacgtc
gagatttataccgacgagtcgcgcagcaaggtcgcgctgacctggaacaacctgcgccag
cagagcgagcgtccggtggtggatggggtgcgtcgcccgaaccgttgcctggctgatttc
atcgcgccgaagtcgagcggcgtggccgactacattggcctgttcgcggtcacggccggg
atcggcgtggacaagaaggaggcgcagttcgaggccgaccacgacgactacagcgccatc
atgctcaaggcgctggccgatcgtctggccgaggcgttcgccgaatgcctgcacgagcgc
gtgcgcaaggatctctggggctacgacgccgcagagtcgctgaacaatgatcagctcgtc
gccgaggcgtatcgcggtattcgtccggcacccggctatccggcgtgcccggagcacacg
gtcaaggcgccgatgttcgcgttcctcgatgctgccgacatcggcatgggcattaccgag
gggctggccatgacgccggcggcatcggtgagcggcttctacctgtcgcatccggactcg
acctacttcagcattggcaagatcggccaggaccagctcgacgatatggtggcccgtcgc
ggcgaggaccgccttacgctcgagcgcgctctggcgccgaacctgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (30)   

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