KEGG   Ralstonia mannitolilytica: TK49_18245
Entry
TK49_18245        CDS       T03778                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
rmn  Ralstonia mannitolilytica
Pathway
rmn00290  Valine, leucine and isoleucine biosynthesis
rmn00620  Pyruvate metabolism
rmn01100  Metabolic pathways
rmn01110  Biosynthesis of secondary metabolites
rmn01210  2-Oxocarboxylic acid metabolism
rmn01230  Biosynthesis of amino acids
Module
rmn_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:rmn00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    TK49_18245
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TK49_18245
Enzymes [BR:rmn01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     TK49_18245
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AJW46686
Position
2:353273..354985
AA seq 570 aa
MLKNPATKYRPFPAIALADRTWPNKTITRAPIWMSTDLRDGNQALFEPMNAERKMRMFKM
LVQIGFKEIEAAFPAASQTDFDFVRELIEGGHIPDGVAIEVLTQAREDLIRRTMESLRGA
KRAIIHVYNATAPVFRRTVFNTDREGVKRIAVQSAKLIREIAQTMPETQWTYQYSPEVFS
GTELDFALEVCNAVTEVWEPTPEHKIIFNLPATVEMATPNIYADQIEWMHRNLARRDSII
LSVHPHNDRGTAVAAAELAVMAGADRVEGCLFGNGERTGNVDLVTLALNLYSQGVDPGLD
FSHINDVARTCEDCTQLPVHPRHPYVGDLVFTAFSGSHQDAIKKGFAVQKPDAIWEMPYL
PIDPADVGRTYDSIIRVNSQSGKGGIAYLLESGYGVAMPRRLQVEFSSTVQKLTDESGRE
VTAADIWALFQQTYLRSDGAIGYVSHRLTEQEDGSQHIRLVVNIADREHICEGVGNGPLD
ALVHALSHVLTAPVSIHHYEERALGQGANADAIAFAEVAAPGVAGSVFGVGVDANLTTAS
IRAVVGGVNRLITHAGSGMLRSGKNEAQAA
NT seq 1713 nt   +upstreamnt  +downstreamnt
atgttgaagaaccccgccaccaagtaccgccccttccccgccatcgccctcgccgatcgc
acctggcccaacaagacgatcacccgtgccccgatctggatgagcacggacctgcgcgac
ggcaaccaggccttgttcgagcccatgaacgccgagcgcaagatgcgcatgttcaagatg
ctcgtgcagatcggcttcaaggaaatcgaagccgctttccccgctgcctcccaaaccgat
tttgattttgtccgcgagctgatcgagggcggacacatccctgacggcgtggccatcgaa
gtgctcacgcaggcccgcgaagacctgatccgccgcacgatggaatcgctgcgcggcgcc
aaacgcgccatcatccacgtctacaacgcgaccgcgccggtgttccgccgcacggtgttc
aacaccgaccgcgaaggcgtcaagcgcattgccgtgcaaagcgccaagctgatccgcgag
attgcgcagacgatgcccgagacgcagtggacgtatcagtacagccccgaagtcttcagc
ggcaccgagctggattttgcgctggaggtctgcaacgcggtgaccgaagtctgggagccg
acgcccgagcacaagatcatcttcaacctgcctgccacggtggagatggccacgccaaac
atctacgccgaccagatcgaatggatgcatcgcaacctggcgcgccgcgattcgatcatc
ctctccgtgcatccgcacaatgaccgcggcacggccgtggcagcggctgaactggcggtg
atggccggcgccgatcgcgtggaaggctgcctgttcggcaatggcgagcgcaccggcaac
gtggacctcgtcacactcgcgctgaacctgtattcgcaaggagtcgatccgggcctggat
ttttcgcacatcaacgacgtggcccgcacgtgcgaagactgcacgcagctgccggtgcat
ccgcgccatccgtacgtgggcgacctggtgttcacggcgttctcgggctcgcaccaggat
gcgatcaagaagggctttgccgtgcagaagcccgacgccatctgggaaatgccgtacctg
ccgatcgacccggccgacgtgggccgcacgtacgactcgatcattcgcgtgaacagccag
tcgggcaagggcgggatcgcatacctgctcgaatcgggctatggcgtggcgatgccgcgg
cgcctgcaggtggagttcagcagcaccgtgcagaagctgaccgacgaaagcggccgcgaa
gtgaccgccgccgacatctgggcactgttccagcagacgtatctgcgcagcgatggcgca
atcggctacgtgtcgcaccgcctgaccgagcaggaagacggcagccagcacatccgcctg
gtcgtcaacattgccgatcgtgagcacatctgcgaaggcgtgggcaacgggccgctggat
gcgctcgtgcatgcgctgtcgcacgtgctgacggcacccgtgtcgatccaccactatgaa
gaacgtgcactgggccaaggcgccaatgccgacgcgatcgctttcgcggaagtggcagcg
ccgggcgtggccggcagcgtgttcggcgtgggcgtggatgccaacctgaccaccgcgtcg
atccgcgcggtggtgggcggcgtcaaccggctgatcacccacgcgggcagcggcatgctg
cgcagcggcaagaacgaggcacaagccgcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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