KEGG   REACTION: R00226
Entry
R00226                      Reaction                               
Name
pyruvate:pyruvate acetaldehydetransferase (decarboxylating);
(S)-2-acetolactate pyruvate-lyase (carboxylating)
Definition
(S)-2-Acetolactate + CO2 <=> 2 Pyruvate
Equation
C06010 + C00011 <=> 2 C00022
Comment
TPP-dependent enzymatic reaction (R00014+R04672)
Reaction class
RC00106  C00022_C06010
Enzyme
2.2.1.6
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn00650  Butanoate metabolism
rn00660  C5-Branched dibasic acid metabolism
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.6
     R00226  (S)-2-Acetolactate + CO2 <=> 2 Pyruvate
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.2.1.6
   R00006  2-Acetolactate
    R00226  (S)-2-Acetolactate
Orthology
K01652  acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  acetolactate synthase I/III small subunit [EC:2.2.1.6]
K11258  acetolactate synthase II small subunit [EC:2.2.1.6]
Other DBs
RHEA: 25252

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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