KEGG   REACTION: R00311Help
Entry
R00311                      Reaction                               

Name
protoheme,NADPH---hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
Definition
Heme + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Biliverdin + CO + Fe2+ + 3 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Equation
C00032 + 3 C03024 + 3 C00007 <=> C00500 + C00237 + C14818 + 3 C03161 + 3 C00001
Comment
multi-step reaction
Reaction class
RC01270  C00032_C00500
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00510  heme oxygenase 1 [EC:1.14.14.18]
K21418  heme oxygenase 2 [EC:1.14.14.18]
Other DBs
RHEA: 21767

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