KEGG   REACTION: R00352
Entry
R00352                      Reaction                               
Name
acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
Definition
ATP + Citrate + CoA <=> ADP + Orthophosphate + Acetyl-CoA + Oxaloacetate
Equation
Comment
multi-step reaction (see R01322+R00354)
Reaction class
RC00002  C00002_C00008
RC00004  C00010_C00024
RC00067  C00036_C00158
Enzyme
Pathway
rn00020  Citrate cycle (TCA cycle)
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00173  Reductive citrate cycle (Arnon-Buchanan cycle)
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.8
     R00352  ATP + Citrate + CoA <=> ADP + Orthophosphate + Acetyl-CoA + Oxaloacetate
Overall reaction [br08210.html]
 Carbon fixation
  R00352
Orthology
K01648  ATP citrate (pro-S)-lyase [EC:2.3.3.8]
K15230  ATP-citrate lyase alpha-subunit [EC:2.3.3.8]
K15231  ATP-citrate lyase beta-subunit [EC:2.3.3.8]
Other DBs
RHEA: 21163

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